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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046451
Ensembl Protein ID ENSP00000377942.4
UniProt Accession Q96DX4; Q6UX21; Q8ND53; RSPRY_HUMAN
Genbank Protein ID BAB85558.1; AAQ88912.1; BAD18809.1; AAH13173.1; CAD39064.1
Protein Name RING finger and SPRY domain-containing protein 1
Genbank Nucleotide ID AB075852; AY358548; AK172845; BC013173; AL834402
Gene Name RSPRY1; KIAA1972; UNQ328/PRO444
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000159579.13 ENST00000394420.8 ENSP00000377942.4
ENSG00000159579.13 ENST00000561641.1 ENSP00000455367.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDHINTMenthaInWeb_IM
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
PHOSIDABioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 50.00 3.00e-137 485.00 IUUC-Cel-018326
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Homo sapiens
Protein Sequence
(Fasta)
MIVFGWAVFL ASRSLGQGLL LTLEEHIAHF LGTGGAATTM GNSCICRDDS GTDDSVDTQQ 60
QQAENSAVPT ADTRSQPRDP VRPPRRGRGP HEPRRKKQNV DGLVLDTLAV IRTLVDNDQE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046451|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGACTTGATT GGGCCATTCA CGCCTCAGGA TGAGGACTGG CCAGTCTGCG CCTGGAGGGC 60
GGGCCGGTCC CGCTGATCAC GTGACACGAT TTTTGAAAGG TGATTGGCTG TCAAGGAGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046451|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0242--Dwarfism
KW-0325--Glycoprotein
KW-0991--Mental retardation
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR016024--ARM-type_fold
IPR001870--B30.2/SPRY
IPR001370--BIR_rpt
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR001841--Znf_RING
PROSITE

PS50188--B302_SPRY
PS50089--ZF_RING_2
Pfam

PF00622--SPRY
SMART

SM00184--RING
SM00449--SPRY
Gene Ontology

GO:0005576--C:extracellular region
GO:0008270--F:zinc ion binding
KEGG hsa:89970
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002349 Ailuropoda melanoleuca 97.05 0.00e+00 1118.00
IUUC-Apl-003470 Anas platyrhynchos 86.63 0.00e+00 972.00
IUUC-Aca-005153 Anolis carolinensis 83.79 0.00e+00 928.00
IUUC-Ame-010885 Astyanax mexicanus 78.31 0.00e+00 838.00
IUUC-Bta-013096 Bos taurus 96.88 0.00e+00 1113.00
IUUC-Cel-018326 Caenorhabditis elegans 50.00 3.00e-136 479.00
IUUC-Cja-019829 Callithrix jacchus 99.31 0.00e+00 1135.00
IUUC-Cfa-020086 Canis familiaris 97.22 0.00e+00 1118.00
IUUC-Cpo-021296 Cavia porcellus 96.70 0.00e+00 1112.00
IUUC-Csa-023390 Chlorocebus sabaeus 99.48 0.00e+00 1137.00
IUUC-Cho-024722 Choloepus hoffmanni 89.54 0.00e+00 842.00
IUUC-Cin-025317 Ciona intestinalis 54.30 1.00e-146 513.00
IUUC-Csv-026376 Ciona savignyi 55.56 1.00e-132 466.00
IUUC-Dre-028463 Danio rerio 77.93 0.00e+00 858.00
IUUC-Dno-028922 Dasypus novemcinctus 96.70 0.00e+00 1108.00
IUUC-Dor-030223 Dipodomys ordii 95.83 0.00e+00 1083.00
IUUC-Ete-032348 Echinops telfairi 96.25 0.00e+00 870.00
IUUC-Eca-033567 Equus caballus 95.66 0.00e+00 1097.00
IUUC-Eeu-034988 Erinaceus europaeus 98.73 2.00e-146 512.00
IUUC-Fca-036016 Felis catus 97.40 0.00e+00 1119.00
IUUC-Fal-036945 Ficedula albicollis 86.63 0.00e+00 968.00
IUUC-Gmo-039352 Gadus morhua 75.17 0.00e+00 808.00
IUUC-Gga-040260 Gallus gallus 92.58 2.00e-139 488.00
IUUC-Gac-041492 Gasterosteus aculeatus 77.03 0.00e+00 839.00
IUUC-Ggo-045400 Gorilla gorilla 99.83 0.00e+00 1108.00
IUUC-Itr-048369 Ictidomys tridecemlineatus 96.35 0.00e+00 1112.00
IUUC-Lch-050072 Latimeria chalumnae 81.66 0.00e+00 907.00
IUUC-Loc-052918 Lepisosteus oculatus 80.31 0.00e+00 841.00
IUUC-Laf-053333 Loxodonta africana 96.35 0.00e+00 1092.00
IUUC-Mcc-055288 Macaca mulatta 99.48 0.00e+00 1137.00
IUUC-Meu-056506 Macropus eugenii 87.07 0.00e+00 777.00
IUUC-Mga-059857 Meleagris gallopavo 86.63 0.00e+00 968.00
IUUC-Mmr-061371 Microcebus murinus 97.74 0.00e+00 1117.00
IUUC-Mdo-062226 Monodelphis domestica 88.37 0.00e+00 981.00
IUUC-Mmu-063459 Mus musculus 96.70 0.00e+00 1095.00
IUUC-Mpu-065988 Mustela putorius furo 97.40 0.00e+00 1120.00
IUUC-Mlu-067249 Myotis lucifugus 96.35 0.00e+00 1109.00
IUUC-Nle-069879 Nomascus leucogenys 99.65 0.00e+00 1117.00
IUUC-Opr-070736 Ochotona princeps 70.77 0.00e+00 695.00
IUUC-Ont-072592 Oreochromis niloticus 78.21 0.00e+00 854.00
IUUC-Oan-073066 Ornithorhynchus anatinus 90.10 0.00e+00 723.00
IUUC-Ocu-074838 Oryctolagus cuniculus 92.53 0.00e+00 1042.00
IUUC-Ola-087340 Oryzias latipes 76.82 0.00e+00 850.00
IUUC-Oga-088478 Otolemur garnettii 91.35 0.00e+00 1033.00
IUUC-Oar-089877 Ovis aries 96.88 0.00e+00 1114.00
IUUC-Ptr-090721 Pan troglodytes 100.00 0.00e+00 1144.00
IUUC-Pan-091726 Papio anubis 99.31 0.00e+00 1135.00
IUUC-Psi-093743 Pelodiscus sinensis 85.53 0.00e+00 631.00
IUUC-Pma-094157 Petromyzon marinus 78.89 2.00e-167 581.00
IUUC-Pfo-097306 Poecilia formosa 81.93 0.00e+00 862.00
IUUC-Pab-098219 Pongo abelii 99.83 0.00e+00 1142.00
IUUC-Pca-100452 Procavia capensis 96.18 0.00e+00 1103.00
IUUC-Pva-102312 Pteropus vampyrus 97.05 0.00e+00 1113.00
IUUC-Rno-105587 Rattus norvegicus 96.54 0.00e+00 1097.00
IUUC-Sha-106659 Sarcophilus harrisii 89.24 0.00e+00 1001.00
IUUC-Sar-113171 Sorex araneus 79.96 0.00e+00 748.00
IUUC-Ssc-115976 Sus scrofa 97.40 0.00e+00 1122.00
IUUC-Tgu-116991 Taeniopygia guttata 86.98 0.00e+00 971.00
IUUC-Tru-118707 Takifugu rubripes 73.85 0.00e+00 844.00
IUUC-Tsy-119227 Tarsius syrichta 96.70 0.00e+00 1096.00
IUUC-Tni-120291 Tetraodon nigroviridis 76.18 0.00e+00 855.00
IUUC-Tbe-128008 Tupaia belangeri 74.29 5.00e-161 561.00
IUUC-Ttr-129268 Tursiops truncatus 95.14 0.00e+00 1091.00
IUUC-Vpa-130102 Vicugna pacos 96.88 0.00e+00 1110.00
IUUC-Xtr-132874 Xenopus tropicalis 80.14 0.00e+00 909.00
Created Date 25-Jun-2017

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