iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afl-008674

Ensembl Protein ID

EED53276

UniProt Accession

B8N857; B8N857_ASPFN

Genbank Protein ID

EED53276.1

Protein Name

Ubiquitin-like activating enzyme (UbaB), putative

Genbank Nucleotide ID

EQ963475

Gene Name

AFLA_106510

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AFLA_106510	EED53276	EED53276

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.10e-103	345.6	16	422

Active Site

Position(s)	Description	Evidence
176	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 14   eklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVv 114
           ++lk+++vllvGagg+GcEllKnL l+G+g+i+++D dt+++snlnrqFLfr e+++ksKA va+e ++++ p+ ++ea++ +i++   ++ +f +fdvV+
   Q: 16   RRLKESRVLLVGAGGIGCELLKNLLLSGFGEIHIIDLDTIDLSNLNRQFLFRFEHIKKSKALVAKEVAQKFQPSAKLEAYHANIKDSRFNVDWFATFDVVF 116
           79****************************************************************************************99********* PP
   S: 115  laldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa..vlfnklleeeageeevlekldse 213
           +aldn++arr+vnr+cl+a+vpliesgt+G+ Gqv+vi kg tecy+c+ ++  k++P+ct+++tp+++ h+i+wa  +lf +l+++++ e+ +l+ +   
   Q: 117  NALDNLDARRHVNRMCLAADVPLIESGTTGFNGQVQVIKKGQTECYDCNSKEVPKSFPVCTIRSTPSQPIHCIVWAksYLFPELFGTSEDETPELDST--- 214
           ******************************************************************************99999998776666555532... PP
   S: 214  ekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv....................sfcsnaealq........vp 286
             e++ +++   + ++  ++++  +e  +++   + +   k ++k f+ di + +++++++                             +          
   Q: 215  --EDVNNAE---EIANLRKEAQALKE--IRESMGSPEFAHKVFTKVFKEDIDRLRGMEDMWkmrkapepldfekiqeetstI--------EptiscndqKV 300
           ..3333333...22222222222222..3333334444478999*****************666665555444333333332........03333333355 PP
   S: 287  ekvekdeevvkasap...........lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlraeslgiepkldddlikeiagniipaiattnavv 376
           ++ ++d  v+k+s             l+  l++l    +k++ kp  l f+kdd + +d+vta anlra+ +giep  +++++k++agniipaiattna+ 
   Q: 301  WTLAEDLVVFKDSVIlltdiyrsldrLSKRLKTLLDT-TKSDVKP-ILVFDKDDVDTLDFVTASANLRATIFGIEP-KSKFDTKQMAGNIIPAIATTNAMT 398
           8888888777777768888777753322222222222.2333344.699***************************.************************ PP
   S: 377  gGlaaqEviKvvsgkfeplknffl 400
           +Gl++++++Kv++ ++ + k +fl
   Q: 399  AGLCVLQAFKVLKDDYAHAKMIFL 422
           ****************99998886 PP

Organism

Aspergillus flavus

Protein Sequence
(Fasta)

MPRDTYSKRS LGTLSRRLKE SRVLLVGAGG IGCELLKNLL LSGFGEIHII DLDTIDLSNL 60
NRQFLFRFEH IKKSKALVAK EVAQKFQPSA KLEAYHANIK DSRFNVDWFA TFDVVFNALD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGCGAG ACACCTACTC CAAGCGCTCG CTCGGGACCT TGTCCAGACG CTTAAAAGAG 60
GTATTCAATT CTTCTGGCCC TGAATGTGTG CTTATTCTTA TGTTAGAAGC TAATTAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR019572--UBA_E1_Cys
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF10585--UBA_e1_thiolCys

Gene Ontology

GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

KEGG

afv:AFLA_106510

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	43.62	5.00e-108	383.00
IUUC-Aml-001662	Ailuropoda melanoleuca	42.25	6.00e-104	369.00
IUUC-Atr-002636	Amborella trichopoda	43.54	9.00e-107	379.00
IUUC-Apl-003369	Anas platyrhynchos	40.07	8.00e-97	345.00
IUUC-Aca-004490	Anolis carolinensis	43.87	6.00e-89	319.00
IUUC-Aly-006359	Arabidopsis lyrata	41.42	3.00e-100	357.00
IUUC-Ath-007667	Arabidopsis thaliana	42.16	6.00e-105	372.00
IUUC-Ago-007844	Ashbya gossypii	41.31	7.00e-101	359.00
IUUC-Acl-008270	Aspergillus clavatus	81.44	0.00e+00	972.00
IUUC-Afu-008883	Aspergillus fumigatus	78.02	0.00e+00	982.00
IUUC-Ani-009500	Aspergillus nidulans	74.56	0.00e+00	943.00
IUUC-Ang-009535	Aspergillus niger	79.74	0.00e+00	999.00
IUUC-Aor-010223	Aspergillus oryzae	97.53	0.00e+00	1206.00
IUUC-Ate-010282	Aspergillus terreus	75.04	0.00e+00	897.00
IUUC-Ame-011736	Astyanax mexicanus	44.49	6.00e-111	392.00
IUUC-Bgr-012166	Blumeria graminis	54.42	2.00e-179	620.00
IUUC-Bta-012589	Bos taurus	42.36	2.00e-105	374.00
IUUC-Bci-013802	Botrytis cinerea	62.07	0.00e+00	683.00
IUUC-Bdi-014697	Brachypodium distachyon	43.10	1.00e-106	378.00
IUUC-Bol-016315	Brassica oleracea	41.74	2.00e-105	374.00
IUUC-Bra-017009	Brassica rapa	41.93	1.00e-105	375.00
IUUC-Cel-018708	Caenorhabditis elegans	36.91	1.00e-100	358.00
IUUC-Cja-019120	Callithrix jacchus	41.99	2.00e-104	370.00
IUUC-Cfa-021061	Canis familiaris	42.17	1.00e-104	372.00
IUUC-Cpo-021842	Cavia porcellus	42.16	6.00e-105	372.00
IUUC-Csa-024104	Chlorocebus sabaeus	41.71	2.00e-104	370.00
IUUC-Cho-024332	Choloepus hoffmanni	43.30	4.00e-89	320.00
IUUC-Cin-025363	Ciona intestinalis	41.30	8.00e-100	355.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	58.94	4.00e-177	612.00
IUUC-Cne-026888	Cryptococcus neoformans	41.79	6.00e-109	386.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.90	2.00e-59	221.00
IUUC-Dre-028420	Danio rerio	42.93	4.00e-112	396.00
IUUC-Dno-030041	Dasypus novemcinctus	42.55	3.00e-105	374.00
IUUC-Dse-031504	Dothistroma septosporum	48.91	2.00e-159	554.00
IUUC-Dme-031771	Drosophila melanogaster	65.31	9.00e-67	246.00
IUUC-Ete-033037	Echinops telfairi	40.22	6.00e-92	329.00
IUUC-Eca-033774	Equus caballus	42.31	9.00e-98	348.00
IUUC-Eeu-035074	Erinaceus europaeus	36.28	1.00e-57	215.00
IUUC-Fca-036508	Felis catus	42.37	2.00e-98	351.00
IUUC-Fal-036813	Ficedula albicollis	41.67	1.00e-99	355.00
IUUC-Fox-038056	Fusarium oxysporum	54.74	0.00e+00	640.00
IUUC-Fso-038223	Fusarium solani	55.40	9.00e-180	621.00
IUUC-Gmo-038526	Gadus morhua	41.83	3.00e-96	343.00
IUUC-Ggr-039767	Gaeumannomyces graminis	58.93	7.00e-167	578.00
IUUC-Gga-040981	Gallus gallus	41.06	2.00e-99	354.00
IUUC-Gac-041437	Gasterosteus aculeatus	45.25	5.00e-109	386.00
IUUC-Gma-043041	Glycine max	42.24	1.00e-110	391.00
IUUC-Ggo-045358	Gorilla gorilla	43.31	9.00e-101	358.00
IUUC-Hsa-046068	Homo sapiens	41.71	2.00e-104	370.00
IUUC-Hvu-047646	Hordeum vulgare	43.28	2.00e-106	378.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	42.46	2.00e-105	374.00
IUUC-Kpa-049301	Komagataella pastoris	60.40	8.00e-46	176.00
IUUC-Lch-049565	Latimeria chalumnae	44.17	1.00e-113	401.00
IUUC-Lpe-050884	Leersia perrieri	43.64	3.00e-107	380.00
IUUC-Loc-052493	Lepisosteus oculatus	43.55	5.00e-113	399.00
IUUC-Lma-053117	Leptosphaeria maculans	61.17	0.00e+00	656.00
IUUC-Laf-054518	Loxodonta africana	42.60	3.00e-105	373.00
IUUC-Mcc-055334	Macaca mulatta	41.71	1.00e-104	372.00
IUUC-Mor-057137	Magnaporthe oryzae	58.83	3.00e-152	530.00
IUUC-Mpo-057449	Magnaporthe poae	57.77	1.00e-169	588.00
IUUC-Mtr-058045	Medicago truncatula	42.04	3.00e-112	397.00
IUUC-Mla-058864	Melampsora laricipopulina	47.69	8.00e-99	352.00
IUUC-Mga-059422	Meleagris gallopavo	38.08	6.00e-77	280.00
IUUC-Mvi-060536	Microbotryum violaceum	48.38	3.00e-123	434.00
IUUC-Mmr-061161	Microcebus murinus	42.21	2.00e-103	368.00
IUUC-Mdo-061802	Monodelphis domestica	42.86	2.00e-105	374.00
IUUC-Mmu-064357	Mus musculus	42.86	7.00e-110	389.00
IUUC-Mac-065475	Musa acuminata	41.10	1.00e-105	375.00
IUUC-Mpu-066895	Mustela putorius furo	43.02	1.00e-104	372.00
IUUC-Mlu-067862	Myotis lucifugus	42.02	2.00e-106	378.00
IUUC-Nfi-068385	Neosartorya fischeri	80.13	0.00e+00	1007.00
IUUC-Ncr-068885	Neurospora crassa	59.83	0.00e+00	658.00
IUUC-Nle-069524	Nomascus leucogenys	41.76	1.00e-103	368.00
IUUC-Opr-071038	Ochotona princeps	43.39	4.00e-112	396.00
IUUC-Ont-071719	Oreochromis niloticus	42.76	4.00e-113	399.00
IUUC-Oan-072877	Ornithorhynchus anatinus	41.29	9.00e-97	345.00
IUUC-Ocu-074080	Oryctolagus cuniculus	42.64	6.00e-105	373.00
IUUC-Oba-075936	Oryza barthii	43.22	7.00e-107	379.00
IUUC-Obr-076841	Oryza brachyantha	43.43	6.00e-107	379.00
IUUC-Ogl-077686	Oryza glaberrima	42.89	5.00e-108	383.00
IUUC-Ogu-078597	Oryza glumaepatula	41.89	4.00e-104	370.00
IUUC-Oin-079791	Oryza indica	43.22	7.00e-107	379.00
IUUC-Olo-081009	Oryza longistaminata	43.22	7.00e-107	379.00
IUUC-Ome-081327	Oryza meridionalis	39.53	8.00e-100	355.00
IUUC-Oni-082334	Oryza nivara	42.15	1.00e-104	371.00
IUUC-Opu-083447	Oryza punctata	43.43	2.00e-107	380.00
IUUC-Oru-084977	Oryza rufipogon	43.22	7.00e-107	379.00
IUUC-Osa-086160	Oryza sativa	47.07	3.00e-101	360.00
IUUC-Ola-087415	Oryzias latipes	42.43	7.00e-109	385.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.04	1.00e-103	368.00
IUUC-Oga-088434	Otolemur garnettii	42.18	1.00e-104	371.00
IUUC-Oar-089872	Ovis aries	41.63	6.00e-98	349.00
IUUC-Ptr-091212	Pan troglodytes	41.71	2.00e-104	370.00
IUUC-Pan-092708	Papio anubis	64.71	3.00e-64	237.00
IUUC-Psi-093703	Pelodiscus sinensis	41.17	6.00e-98	349.00
IUUC-Pno-094953	Phaeosphaeria nodorum	58.23	0.00e+00	657.00
IUUC-Ppa-095963	Physcomitrella patens	44.95	2.00e-103	368.00
IUUC-Pfo-097515	Poecilia formosa	47.81	7.00e-110	389.00
IUUC-Pab-097951	Pongo abelii	39.35	9.00e-79	285.00
IUUC-Pop-099703	Populus trichocarpa	38.55	4.00e-95	340.00
IUUC-Pca-100426	Procavia capensis	43.28	4.00e-106	376.00
IUUC-Ppe-101152	Prunus persica	42.64	1.00e-111	395.00
IUUC-Pva-102792	Pteropus vampyrus	40.74	7.00e-96	342.00
IUUC-Pgr-103592	Puccinia graminis	40.30	4.00e-119	420.00
IUUC-Ptt-103805	Puccinia triticina	40.11	3.00e-99	353.00
IUUC-Pte-104215	Pyrenophora teres	58.42	0.00e+00	714.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	58.21	0.00e+00	721.00
IUUC-Rno-106117	Rattus norvegicus	39.63	1.00e-110	391.00
IUUC-Sce-106177	Saccharomyces cerevisiae	42.70	4.00e-100	357.00
IUUC-Sha-107006	Sarcophilus harrisii	42.70	2.00e-105	374.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	49.32	1.00e-145	508.00
IUUC-Spo-108020	Schizosaccharomyces pombe	50.36	4.00e-137	479.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	55.93	0.00e+00	687.00
IUUC-Smo-109264	Selaginella moellendorffii	42.01	6.00e-98	349.00
IUUC-Sit-110581	Setaria italica	42.00	2.00e-107	381.00
IUUC-Sly-111870	Solanum lycopersicum	41.08	9.00e-107	379.00
IUUC-Stu-112283	Solanum tuberosum	41.53	3.00e-107	380.00
IUUC-Sar-113432	Sorex araneus	59.54	7.00e-42	163.00
IUUC-Sbi-114075	Sorghum bicolor	41.86	3.00e-107	380.00
IUUC-Sre-114926	Sporisorium reilianum	47.54	9.00e-124	435.00
IUUC-Ssc-116281	Sus scrofa	64.71	2.00e-63	233.00
IUUC-Tgu-117247	Taeniopygia guttata	42.31	4.00e-100	356.00
IUUC-Tru-118075	Takifugu rubripes	41.47	1.00e-99	355.00
IUUC-Tsy-119398	Tarsius syrichta	63.71	1.00e-42	166.00
IUUC-Tni-120771	Tetraodon nigroviridis	37.81	2.00e-82	298.00
IUUC-Tca-121651	Theobroma cacao	42.72	6.00e-112	396.00
IUUC-Tre-122224	Trichoderma reesei	56.64	1.00e-167	581.00
IUUC-Tvi-122634	Trichoderma virens	58.27	2.00e-166	577.00
IUUC-Tae-123607	Triticum aestivum	43.40	3.00e-107	380.00
IUUC-Tur-126417	Triticum urartu	41.85	6.00e-108	382.00
IUUC-Tme-127016	Tuber melanosporum	58.06	1.00e-179	620.00
IUUC-Tbe-127678	Tupaia belangeri	63.71	2.00e-42	165.00
IUUC-Ttr-128598	Tursiops truncatus	40.70	2.00e-97	347.00
IUUC-Uma-129612	Ustilago maydis	45.60	4.00e-111	393.00
IUUC-Vda-129811	Verticillium dahliae	57.54	5.00e-166	575.00
IUUC-Vpa-130732	Vicugna pacos	35.78	1.00e-65	242.00
IUUC-Vvi-130832	Vitis vinifera	41.78	2.00e-104	370.00
IUUC-Xtr-132823	Xenopus tropicalis	43.68	1.00e-93	335.00
IUUC-Xma-133552	Xiphophorus maculatus	47.37	6.00e-109	386.00
IUUC-Yli-134666	Yarrowia lipolytica	45.94	3.00e-114	403.00
IUUC-Zma-135547	Zea mays	41.21	1.00e-107	382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence