iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017476.3	ENSMMUT00000024572.3	ENSMMUP00000022999.3
ENSMMUG00000017476.3	ENSMMUT00000074967.1	ENSMMUP00000059683.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.90e-77	261.8	442	926

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgye 88
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf  l   +  ++    +++l+a +   + fs   
   Q: 442  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFGFLEhsQVIRTGWRGKNFLSASW--TPWFSPGT 519
           9*****************************.....4433....3579**********9973333455666677777665..566***** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqD++E+l++lld+l+ee      k+ ++ +++ k+++s + +e+++  +++ ++++F+g++ ++i cl c nvssree f+dlsl++p
   Q: 520  QQDCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSSPSLPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFP 603
           *******************.....678888888888889999999******************************************** PP
   S: 178  gkeetkke................................................................................. 185
             e +  +                                                                                 
   Q: 604  PPERCRRRrlgsvmrptgditaqellptasaqgpgrvgprrqrkhcitgdtpptsldiegldskeaggqssqeekverdeegkeegtek 692
           9998877799******************************************************************************* PP
   S: 186  ...................................................................slqdcLesftkeeelegenkyy 207
                                                                              s+ d+ + f ++e+l+ en+yy
   Q: 693  eeageeeeestrgeeereeeeeveekveketekeaeqekeedslgagshldatipsgeqmcgsegsrSVLDLVNYFLSPEKLTAENRYY 781
           ***************************************************************************************** PP
   S: 208  cekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHY 295
           ce+c ++q+aek ++l++ P++Lil L Rfsf+ ++++r+ki + +++pl L l     +        + Y+L++vvvHsG s++sGHY
   Q: 782  CESCASLQDAEKVVELSQGPRYLILTLLRFSFDLRTMRRRKILDDISIPLLLRLPLAGGR-------GQAYDLCSVVVHSGvSSESGHY 863
           *************************************************99999855555.......89******************** PP
   S: 296  vayvkn................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
           ++y+++                 +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 864  YCYAREgaarpapslgtadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 926
           ******99999999999999888999*******************999************985 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDKILEAVVT SSYPVSVKQG LVRRVLEAAR QPLEREQCLA LLALGARLYV GGAEELPRRV 60
GCQLLHVAGR HHPDVFAEFF SARRVLRLLQ GGAGPPGPRA LACVQLGLQL LPEGPAADEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCTTGGAGGC GGTGGTGACG TCGTCATACC CGGTCAGCGT GAAGCAGGGG 60
CTGGTTCGGC GCGTGCTGGA GGCGGCGCGG CAGCCTCTGG AGCGTGAGCA GTGCCTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	86.27	0.00e+00	951.00
IUUC-Apl-004121	Anas platyrhynchos	66.47	0.00e+00	875.00
IUUC-Bta-012545	Bos taurus	90.91	0.00e+00	1138.00
IUUC-Cja-019731	Callithrix jacchus	96.00	0.00e+00	1184.00
IUUC-Cfa-020095	Canis familiaris	93.03	0.00e+00	1151.00
IUUC-Cpo-021961	Cavia porcellus	91.72	0.00e+00	1137.00
IUUC-Csa-023167	Chlorocebus sabaeus	98.53	0.00e+00	1195.00
IUUC-Dno-029186	Dasypus novemcinctus	82.34	0.00e+00	824.00
IUUC-Dor-030538	Dipodomys ordii	96.06	0.00e+00	958.00
IUUC-Ete-032512	Echinops telfairi	88.93	3.00e-105	375.00
IUUC-Eca-033279	Equus caballus	94.72	0.00e+00	887.00
IUUC-Eeu-035120	Erinaceus europaeus	71.43	0.00e+00	825.00
IUUC-Fca-035969	Felis catus	90.69	0.00e+00	868.00
IUUC-Fal-037625	Ficedula albicollis	66.72	0.00e+00	878.00
IUUC-Gga-040767	Gallus gallus	66.07	0.00e+00	874.00
IUUC-Ggo-045323	Gorilla gorilla	96.20	0.00e+00	944.00
IUUC-Hsa-046124	Homo sapiens	97.16	0.00e+00	1166.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	92.71	0.00e+00	1126.00
IUUC-Laf-053999	Loxodonta africana	86.61	0.00e+00	1117.00
IUUC-Meu-056906	Macropus eugenii	74.19	0.00e+00	974.00
IUUC-Mga-059595	Meleagris gallopavo	69.74	0.00e+00	861.00
IUUC-Mmr-061720	Microcebus murinus	89.47	0.00e+00	1080.00
IUUC-Mdo-062167	Monodelphis domestica	73.59	0.00e+00	969.00
IUUC-Mmu-063298	Mus musculus	87.62	0.00e+00	1596.00
IUUC-Mpu-066195	Mustela putorius furo	92.27	0.00e+00	1134.00
IUUC-Mlu-067583	Myotis lucifugus	86.17	0.00e+00	758.00
IUUC-Opr-070454	Ochotona princeps	90.46	2.00e-159	556.00
IUUC-Ocu-074121	Oryctolagus cuniculus	85.26	0.00e+00	931.00
IUUC-Oga-088593	Otolemur garnettii	93.03	0.00e+00	1125.00
IUUC-Oar-090140	Ovis aries	90.31	0.00e+00	1120.00
IUUC-Pan-092168	Papio anubis	98.82	0.00e+00	1197.00
IUUC-Psi-093707	Pelodiscus sinensis	65.59	0.00e+00	879.00
IUUC-Pab-097614	Pongo abelii	96.74	0.00e+00	1167.00
IUUC-Pca-100683	Procavia capensis	86.48	0.00e+00	1091.00
IUUC-Pva-103146	Pteropus vampyrus	79.11	0.00e+00	999.00
IUUC-Rno-105061	Rattus norvegicus	87.33	0.00e+00	1570.00
IUUC-Sha-106686	Sarcophilus harrisii	71.70	0.00e+00	937.00
IUUC-Tgu-117024	Taeniopygia guttata	66.77	0.00e+00	881.00
IUUC-Tsy-119505	Tarsius syrichta	79.01	2.00e-163	569.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence