iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000014601.1	ENSSHAT00000017322.1	ENSSHAP00000017179.1
ENSSHAG00000014601.1	ENSSHAT00000017323.1	ENSSHAP00000017180.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-42	140.1	511	543
UBD/Beta-Prp	1.60e-67	228.0	271	568

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d  l++s+s D++++vWD+r
   Q: 511  GHTDNITSLTFsPDsSLIASASMDNSVRVWDIR 543
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl...................................lrslsgheaevtavkfspdgki 66
           ++   +spd++lla+g++++++k+w+++++kl                                   ++ l gh ++v++++f +d++ 
   Q: 271  LNTAEISPDNKLLAAGFDNSCVKLWSLRSKKLksephqvdisrirlacdvldeevneeeddddmgteMKILRGHCGPVYSTRFLSDSSG 359
           5667889********************************************************************************** PP
   S: 67   lvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsG 155
           l+++seD+ i+ wdl +++ ++ ++gh + v++l++sp + +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++G
   Q: 360  LLSCSEDMSIRYWDLGSFTNTVLYRGHAYPVWDLDISPCSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATG 447
           ****************************************************************.************************ PP
   S: 156  slDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDg 244
           s+D+tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+
   Q: 448  STDKTVRLWSTQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLIASASMDN 535
           *********************9.****************************************************************** PP
   S: 245  siriWdlrsgdllktlqlhnssvisvavlsfgd 277
           s+r+Wd+r+  ++    ++ s ++ v + ++++
   Q: 536  SVRVWDIRNTYCNAPADGSSSELVGVYTGQMSN 568
           *****9999999988888886666666633333 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYVDSEGPLK QGLRLSQTPE EMAANLTVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNMVQN GLKSTVDSFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATTTTGTG TGTATATGAT TTGAGTGCTA ATTAGAATCT GTTCCAGTCA GGAAAAATAA 60
AAGGCTTAAT TCAAACCAGT AATAGTTATT CCTTGTTAAT AGTTCTAATG AAAGTCTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	93.92	0.00e+00	1077.00
IUUC-Apl-003636	Anas platyrhynchos	93.43	0.00e+00	1130.00
IUUC-Aca-004229	Anolis carolinensis	92.91	0.00e+00	1097.00
IUUC-Ame-010599	Astyanax mexicanus	67.71	0.00e+00	836.00
IUUC-Bta-013404	Bos taurus	89.53	0.00e+00	1025.00
IUUC-Cja-019643	Callithrix jacchus	94.09	0.00e+00	1082.00
IUUC-Cfa-020913	Canis familiaris	94.09	0.00e+00	1080.00
IUUC-Cpo-021777	Cavia porcellus	92.06	0.00e+00	1054.00
IUUC-Csa-024184	Chlorocebus sabaeus	94.09	0.00e+00	1084.00
IUUC-Cho-024638	Choloepus hoffmanni	94.59	0.00e+00	1071.00
IUUC-Cin-025618	Ciona intestinalis	34.95	1.00e-88	320.00
IUUC-Csv-025874	Ciona savignyi	33.49	2.00e-85	310.00
IUUC-Dre-028817	Danio rerio	67.60	0.00e+00	822.00
IUUC-Dno-029969	Dasypus novemcinctus	85.47	0.00e+00	1015.00
IUUC-Dor-031117	Dipodomys ordii	91.72	0.00e+00	1077.00
IUUC-Ete-032712	Echinops telfairi	86.49	0.00e+00	966.00
IUUC-Eca-033742	Equus caballus	94.09	0.00e+00	1080.00
IUUC-Eeu-035096	Erinaceus europaeus	92.40	0.00e+00	1095.00
IUUC-Fca-035769	Felis catus	93.27	0.00e+00	1099.00
IUUC-Fal-036645	Ficedula albicollis	93.20	0.00e+00	1067.00
IUUC-Gmo-038636	Gadus morhua	65.17	0.00e+00	795.00
IUUC-Gga-040144	Gallus gallus	93.07	0.00e+00	1099.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.95	0.00e+00	825.00
IUUC-Ggo-044568	Gorilla gorilla	94.26	0.00e+00	1083.00
IUUC-Hsa-046178	Homo sapiens	94.26	0.00e+00	1083.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	86.15	0.00e+00	1047.00
IUUC-Lch-050501	Latimeria chalumnae	79.33	0.00e+00	885.00
IUUC-Loc-052895	Lepisosteus oculatus	81.67	0.00e+00	641.00
IUUC-Laf-053950	Loxodonta africana	91.05	0.00e+00	1051.00
IUUC-Mcc-055450	Macaca mulatta	94.09	0.00e+00	1080.00
IUUC-Meu-056182	Macropus eugenii	91.89	0.00e+00	1056.00
IUUC-Mga-059619	Meleagris gallopavo	93.24	0.00e+00	1103.00
IUUC-Mmr-061074	Microcebus murinus	93.10	0.00e+00	1088.00
IUUC-Mdo-062307	Monodelphis domestica	97.31	0.00e+00	930.00
IUUC-Mmu-063226	Mus musculus	90.54	0.00e+00	1037.00
IUUC-Mpu-066016	Mustela putorius furo	93.58	0.00e+00	1068.00
IUUC-Mlu-067257	Myotis lucifugus	86.71	0.00e+00	1068.00
IUUC-Nle-070139	Nomascus leucogenys	94.43	0.00e+00	1085.00
IUUC-Opr-070243	Ochotona princeps	89.86	0.00e+00	1059.00
IUUC-Ont-072686	Oreochromis niloticus	68.66	0.00e+00	845.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.40	0.00e+00	841.00
IUUC-Ocu-074525	Oryctolagus cuniculus	93.24	0.00e+00	1094.00
IUUC-Ola-086524	Oryzias latipes	68.66	0.00e+00	863.00
IUUC-Oga-088540	Otolemur garnettii	93.58	0.00e+00	1076.00
IUUC-Oar-089793	Ovis aries	86.66	0.00e+00	963.00
IUUC-Ptr-091154	Pan troglodytes	94.26	0.00e+00	1083.00
IUUC-Pan-092759	Papio anubis	94.09	0.00e+00	1080.00
IUUC-Psi-094008	Pelodiscus sinensis	91.22	0.00e+00	1090.00
IUUC-Pma-094593	Petromyzon marinus	45.67	1.00e-133	469.00
IUUC-Pfo-097409	Poecilia formosa	67.05	0.00e+00	818.00
IUUC-Pab-097946	Pongo abelii	82.94	0.00e+00	930.00
IUUC-Pca-100727	Procavia capensis	87.16	0.00e+00	977.00
IUUC-Pva-103211	Pteropus vampyrus	82.26	0.00e+00	993.00
IUUC-Ptt-103995	Puccinia triticina	44.04	3.00e-69	256.00
IUUC-Rno-105236	Rattus norvegicus	91.22	0.00e+00	1035.00
IUUC-Sar-113381	Sorex araneus	93.92	0.00e+00	1110.00
IUUC-Ssc-116421	Sus scrofa	91.22	0.00e+00	1105.00
IUUC-Tgu-117143	Taeniopygia guttata	93.92	0.00e+00	1135.00
IUUC-Tru-118680	Takifugu rubripes	67.54	0.00e+00	853.00
IUUC-Tsy-119622	Tarsius syrichta	78.72	0.00e+00	825.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.38	0.00e+00	847.00
IUUC-Tbe-127656	Tupaia belangeri	89.77	4.00e-81	295.00
IUUC-Ttr-129171	Tursiops truncatus	90.54	0.00e+00	1042.00
IUUC-Xtr-132241	Xenopus tropicalis	81.28	0.00e+00	961.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence