iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068803

Ensembl Protein ID

ESA44150

UniProt Accession

V5IQU5; V5IQU5_NEUCR

Genbank Protein ID

ESA44150.1

Protein Name

Ubiquitin-conjugating enzyme E

Genbank Nucleotide ID

CM002236

Gene Name

NCU08345

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU08345	ESA44150	ESA44150

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.10e-48	162.7	26	160

Active Site

Position(s)	Description	Evidence
107	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesv 101
           Rl+ el++l+++p +g+sa p+ + +l  w+++i+GpedtpY+g +Fkl++efp +YP+ PP+v f t+i+hPnv+ +G++Cl+ilk  +kW++a++ ++v
   Q: 26   RLQTELMQLMTSPAPGVSAFPSADGNLLSWRATIEGPEDTPYAGLTFKLSFEFPANYPYAPPTVLFRTPIYHPNVDFSGRICLDILK--DKWTAAYNTQTV 124
           99************************************************************************************9..************ PP
   S: 102  llsiqsllaepnpesplneeaaellkknreeykkkv 137
           lls+qsll epn++spln eaael+ k+++ +k+kv
   Q: 125  LLSLQSLLGEPNNASPLNGEAAELWDKDPTLFKTKV 160
           *********************************998 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MGDIQNSAPT FGARKNIDPS QNAVKRLQTE LMQLMTSPAP GVSAFPSADG NLLSWRATIE 60
GPEDTPYAGL TFKLSFEFPA NYPYAPPTVL FRTPIYHPNV DFSGRICLDI LKDKWTAAYN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCCCTGAC AGCAACGCTC GGGCCCGTCA CGGTTGCTGG GGACCTTCCC GCGGTAACCT 60
AGTCAGCTGT GGGGTTATTG GAGGCTGGTT CGTTTCTGCA GTCGTGTAAA CATTGATATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0000209--P:protein polyubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

KEGG

ncr:NCU08345

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	60.56	7.00e-43	164.00
IUUC-Atr-002885	Amborella trichopoda	58.52	4.00e-44	169.00
IUUC-Aly-006086	Arabidopsis lyrata	54.81	3.00e-41	159.00
IUUC-Ath-006897	Arabidopsis thaliana	52.03	1.00e-41	160.00
IUUC-Acl-008223	Aspergillus clavatus	69.66	3.00e-64	235.00
IUUC-Afl-008675	Aspergillus flavus	70.29	2.00e-63	233.00
IUUC-Afu-008997	Aspergillus fumigatus	69.14	2.00e-63	233.00
IUUC-Ani-009470	Aspergillus nidulans	70.86	3.00e-64	235.00
IUUC-Ang-009648	Aspergillus niger	71.43	6.00e-65	237.00
IUUC-Aor-009977	Aspergillus oryzae	76.74	3.00e-52	195.00
IUUC-Ate-010318	Aspergillus terreus	69.66	3.00e-63	232.00
IUUC-Ame-011302	Astyanax mexicanus	54.05	3.00e-43	165.00
IUUC-Bta-013101	Bos taurus	57.69	7.00e-45	171.00
IUUC-Bci-013787	Botrytis cinerea	74.86	1.00e-74	270.00
IUUC-Bdi-014144	Brachypodium distachyon	58.91	9.00e-44	167.00
IUUC-Bol-015613	Brassica oleracea	52.70	2.00e-42	162.00
IUUC-Bra-017562	Brassica rapa	52.70	2.00e-42	162.00
IUUC-Cfa-020588	Canis familiaris	60.71	7.00e-44	167.00
IUUC-Cpo-021384	Cavia porcellus	57.69	8.00e-45	171.00
IUUC-Csa-023437	Chlorocebus sabaeus	57.96	1.00e-45	173.00
IUUC-Cho-024330	Choloepus hoffmanni	64.04	1.00e-37	146.00
IUUC-Csv-025933	Ciona savignyi	63.85	8.00e-45	171.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	77.97	2.00e-77	279.00
IUUC-Cme-027266	Cyanidioschyzon merolae	49.08	2.00e-39	153.00
IUUC-Dre-027375	Danio rerio	51.85	3.00e-44	169.00
IUUC-Dno-029921	Dasypus novemcinctus	58.57	6.00e-42	161.00
IUUC-Dor-030209	Dipodomys ordii	56.41	5.00e-43	164.00
IUUC-Dse-031516	Dothistroma septosporum	66.88	6.00e-59	218.00
IUUC-Dme-031942	Drosophila melanogaster	52.78	1.00e-42	164.00
IUUC-Eca-034073	Equus caballus	60.71	6.00e-44	167.00
IUUC-Eeu-034854	Erinaceus europaeus	63.27	4.00e-32	128.00
IUUC-Fca-035666	Felis catus	60.71	6.00e-44	167.00
IUUC-Fox-037793	Fusarium oxysporum	78.41	6.00e-78	281.00
IUUC-Fso-038151	Fusarium solani	80.00	1.00e-77	280.00
IUUC-Gmo-038894	Gadus morhua	60.94	2.00e-41	159.00
IUUC-Ggr-039730	Gaeumannomyces graminis	87.33	2.00e-67	246.00
IUUC-Gga-040537	Gallus gallus	55.38	3.00e-37	145.00
IUUC-Gac-041346	Gasterosteus aculeatus	58.21	2.00e-40	156.00
IUUC-Gma-043989	Glycine max	56.30	2.00e-42	162.00
IUUC-Ggo-045594	Gorilla gorilla	56.60	1.00e-43	166.00
IUUC-Hsa-046216	Homo sapiens	57.32	4.00e-45	171.00
IUUC-Hvu-047797	Hordeum vulgare	58.91	1.00e-43	167.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	60.71	6.00e-44	167.00
IUUC-Kpa-049294	Komagataella pastoris	57.32	2.00e-57	213.00
IUUC-Lch-049761	Latimeria chalumnae	50.00	2.00e-38	149.00
IUUC-Lpe-051089	Leersia perrieri	55.86	2.00e-43	166.00
IUUC-Loc-052297	Lepisosteus oculatus	61.60	6.00e-42	162.00
IUUC-Lma-053214	Leptosphaeria maculans	71.33	1.00e-58	216.00
IUUC-Laf-054468	Loxodonta africana	55.76	1.00e-44	170.00
IUUC-Mcc-055338	Macaca mulatta	57.96	1.00e-45	173.00
IUUC-Meu-056147	Macropus eugenii	56.41	5.00e-44	168.00
IUUC-Mor-057239	Magnaporthe oryzae	78.98	2.00e-77	279.00
IUUC-Mpo-057491	Magnaporthe poae	87.42	7.00e-78	280.00
IUUC-Mtr-058382	Medicago truncatula	55.56	1.00e-41	160.00
IUUC-Mla-058880	Melampsora laricipopulina	52.73	2.00e-46	176.00
IUUC-Mvi-060528	Microbotryum violaceum	50.00	9.00e-42	161.00
IUUC-Mmr-060747	Microcebus murinus	63.85	2.00e-42	162.00
IUUC-Mdo-062343	Monodelphis domestica	56.41	3.00e-44	169.00
IUUC-Mmu-063563	Mus musculus	57.69	7.00e-45	171.00
IUUC-Mac-064777	Musa acuminata	58.14	3.00e-44	169.00
IUUC-Mpu-066541	Mustela putorius furo	60.00	4.00e-43	165.00
IUUC-Mlu-067388	Myotis lucifugus	60.56	4.00e-43	165.00
IUUC-Nfi-068577	Neosartorya fischeri	69.10	4.00e-63	231.00
IUUC-Opr-070902	Ochotona princeps	60.00	2.00e-43	166.00
IUUC-Ont-071672	Oreochromis niloticus	59.70	2.00e-42	162.00
IUUC-Ocu-074566	Oryctolagus cuniculus	59.86	2.00e-43	166.00
IUUC-Oba-075538	Oryza barthii	60.17	5.00e-39	150.00
IUUC-Ogu-078467	Oryza glumaepatula	58.39	2.00e-44	169.00
IUUC-Oin-079533	Oryza indica	60.17	4.00e-39	151.00
IUUC-Olo-080673	Oryza longistaminata	60.17	4.00e-39	151.00
IUUC-Ome-081483	Oryza meridionalis	60.00	1.00e-43	167.00
IUUC-Oni-082321	Oryza nivara	58.39	2.00e-44	169.00
IUUC-Opu-083245	Oryza punctata	59.23	5.00e-43	165.00
IUUC-Oru-084641	Oryza rufipogon	55.17	7.00e-42	161.00
IUUC-Osa-085992	Oryza sativa	58.39	2.00e-44	169.00
IUUC-Ola-086807	Oryzias latipes	60.29	2.00e-44	169.00
IUUC-Olu-087834	Ostreococcus lucimarinus	56.12	3.00e-41	158.00
IUUC-Oga-089033	Otolemur garnettii	56.69	3.00e-44	168.00
IUUC-Oar-089542	Ovis aries	59.86	2.00e-42	163.00
IUUC-Ptr-091069	Pan troglodytes	57.32	4.00e-45	171.00
IUUC-Pan-092533	Papio anubis	57.23	5.00e-44	168.00
IUUC-Pma-094607	Petromyzon marinus	59.15	1.00e-39	154.00
IUUC-Pno-094829	Phaeosphaeria nodorum	72.34	6.00e-59	217.00
IUUC-Ppa-095861	Physcomitrella patens	55.10	1.00e-43	167.00
IUUC-Pfo-096836	Poecilia formosa	60.94	1.00e-42	163.00
IUUC-Pab-098707	Pongo abelii	57.32	4.00e-45	171.00
IUUC-Pop-099021	Populus trichocarpa	55.71	6.00e-44	167.00
IUUC-Pca-100661	Procavia capensis	57.69	5.00e-45	171.00
IUUC-Ppe-101289	Prunus persica	56.30	7.00e-43	164.00
IUUC-Pva-103235	Pteropus vampyrus	61.94	4.00e-41	158.00
IUUC-Pte-104292	Pyrenophora teres	73.05	4.00e-60	221.00
IUUC-Rno-105501	Rattus norvegicus	57.05	1.00e-44	170.00
IUUC-Sce-106133	Saccharomyces cerevisiae	60.16	9.00e-45	170.00
IUUC-Sha-107205	Sarcophilus harrisii	56.20	3.00e-39	152.00
IUUC-Sja-108009	Schizosaccharomyces japonicus	58.86	1.00e-58	216.00
IUUC-Spo-108136	Schizosaccharomyces pombe	58.38	1.00e-59	219.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	75.98	4.00e-75	271.00
IUUC-Smo-109459	Selaginella moellendorffii	56.85	1.00e-44	170.00
IUUC-Sit-110754	Setaria italica	58.46	9.00e-43	164.00
IUUC-Sly-111137	Solanum lycopersicum	57.94	1.00e-41	160.00
IUUC-Stu-112305	Solanum tuberosum	56.30	1.00e-42	163.00
IUUC-Sbi-114299	Sorghum bicolor	60.31	6.00e-44	168.00
IUUC-Ssc-115625	Sus scrofa	60.71	6.00e-44	167.00
IUUC-Tni-120070	Tetraodon nigroviridis	57.98	2.00e-37	145.00
IUUC-Tca-121158	Theobroma cacao	56.30	1.00e-42	163.00
IUUC-Tre-121973	Trichoderma reesei	79.55	2.00e-78	282.00
IUUC-Tvi-122496	Trichoderma virens	79.43	1.00e-77	280.00
IUUC-Tae-123596	Triticum aestivum	58.91	1.00e-43	167.00
IUUC-Tur-126818	Triticum urartu	59.38	3.00e-33	131.00
IUUC-Tme-127044	Tuber melanosporum	69.93	3.00e-56	208.00
IUUC-Ttr-128548	Tursiops truncatus	63.27	4.00e-32	128.00
IUUC-Vda-129840	Verticillium dahliae	76.57	3.00e-74	268.00
IUUC-Vvi-131685	Vitis vinifera	50.98	8.00e-43	164.00
IUUC-Xtr-132953	Xenopus tropicalis	53.33	5.00e-43	164.00
IUUC-Xma-134093	Xiphophorus maculatus	60.94	1.00e-42	163.00
IUUC-Yli-134548	Yarrowia lipolytica	56.02	6.00e-53	197.00
IUUC-Zma-135751	Zea mays	59.69	2.00e-43	168.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence