iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055707

Ensembl Protein ID

ENSMMUP00000030082.3

UniProt Accession

H9EV88; H9EV88_MACMU

Genbank Protein ID

AFE66297.1; AFH30084.1

Protein Name

Cirhin

Genbank Nucleotide ID

JSUE03026505; JU473280

Gene Name

CIRH1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000022841.3	ENSMMUT00000032153.3	ENSMMUP00000030082.3
ENSMMUG00000022841.3	ENSMMUT00000053804.1	ENSMMUP00000046476.1
ENSMMUG00000022841.3	ENSMMUT00000032154.3	ENSMMUP00000030083.3
ENSMMUG00000022841.3	ENSMMUT00000055428.1	ENSMMUP00000059363.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.10e-15	56.4	210	245
UBD/Beta-Prp	1.70e-42	146.7	33	321

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sdtllvsGsdDgtikvWDlrtgvllks 38
           + v+++af sd++++s    g+++ WD  tg+l+ks
   Q: 210  CIVWGVAFlSDGTVISVDSAGKVQFWDSATGTLVKS 245
           67999**9*99778888888**********999875 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheae..........................................vtav 58
           i+cv++ ++++ la++ +dgt++v++++   + +++  ghe+                                           ++++
   Q: 33   IRCVAYNNQSNRLAVSRTDGTVEVYNLSANYFQEKFfPGHESRatealcwaegqrlfsaglngeimeydlqalnikyavdvfggpIWSM 121
           89******************************999999999876555555555555555555555555555555555555555555555 PP
   S: 59   kfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........tlsghd 137
             sp+g+ l+ g eD+ +k++   +++ +  + + ++++++lsls++psg ++++Gs  ++i v+d+++g+ +++          s+++
   Q: 122  AVSPSGSQLLVGCEDGSVKLFqiTPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGS-IDYISVFDVKSGSAIHKmivdrqhmGVSKRK 209
           555555555555555555555333344444455555555555555555555555555.4455555555555555555333333223333 PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq.......tgec..vrt 217
            +v++v++ + +  ++s    ++v++Wd++tg+l++      + +v+s+++ ++  ++v g   gtv  ++l        +++    + 
   Q: 210  CIVWGVAFLS-DGTVISVDSAGKVQFWDSATGTLVKSHLI-ANADVQSIAVAEQEDSFVVGTAEGTVFHFQLVpvtsnssEKQWvrTKP 296
           3444444444.33444555555555555555555555544.555555555555555555555555555555555544433222222223 PP
   S: 218  lnghtdnvksvrfspnderlvsgssDg 244
           ++ ht  v+ v+ s   + l+sg+ D 
   Q: 297  FQHHTHDVRTVAHS--PTALISGGTDT 321
           55555555555555..55555555543 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

RSTSGAEPES ARARGAGAER GERREGERAA AGIRCVAYNN QSNRLAVSRT DGTVEVYNLS 60
ANYFQEKFFP GHESRATEAL CWAEGQRLFS AGLNGEIMEY DLQALNIKYA VDVFGGPIWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAGCACTT CCGGGGCAGA GCCTGAGAGC GCGCGCGCAC GTGGGGCCGG GGCGGAGAGA 60
GGCGAGCGCC GGGAAGGGGA GCGTGCGGCA GCTGGTGAGT TGGGGAAGGG GCGTGGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001161	Aegilops tauschii	25.12	3.00e-49	190.00
IUUC-Aml-001310	Ailuropoda melanoleuca	94.01	0.00e+00	1332.00
IUUC-Atr-003076	Amborella trichopoda	22.99	3.00e-33	137.00
IUUC-Apl-003367	Anas platyrhynchos	61.14	2.00e-60	224.00
IUUC-Aca-004429	Anolis carolinensis	60.53	4.00e-136	477.00
IUUC-Aly-006271	Arabidopsis lyrata	23.73	7.00e-42	166.00
IUUC-Ath-007331	Arabidopsis thaliana	25.00	9.00e-40	158.00
IUUC-Ago-007843	Ashbya gossypii	27.83	2.00e-36	147.00
IUUC-Acl-008229	Aspergillus clavatus	26.74	2.00e-36	148.00
IUUC-Afl-008438	Aspergillus flavus	26.10	7.00e-36	145.00
IUUC-Afu-008910	Aspergillus fumigatus	25.05	1.00e-34	141.00
IUUC-Ani-009321	Aspergillus nidulans	30.09	3.00e-36	147.00
IUUC-Ang-009592	Aspergillus niger	27.21	7.00e-38	152.00
IUUC-Aor-010220	Aspergillus oryzae	25.77	6.00e-36	146.00
IUUC-Ate-010317	Aspergillus terreus	25.41	2.00e-35	144.00
IUUC-Ame-010957	Astyanax mexicanus	52.91	0.00e+00	750.00
IUUC-Bgr-012057	Blumeria graminis	24.38	8.00e-32	132.00
IUUC-Bta-012473	Bos taurus	91.18	0.00e+00	1288.00
IUUC-Bdi-014203	Brachypodium distachyon	24.12	2.00e-42	167.00
IUUC-Bol-016163	Brassica oleracea	25.18	4.00e-48	186.00
IUUC-Bra-017482	Brassica rapa	24.36	9.00e-48	185.00
IUUC-Cja-019942	Callithrix jacchus	96.11	0.00e+00	1350.00
IUUC-Cfa-020549	Canis familiaris	93.53	0.00e+00	913.00
IUUC-Cpo-022088	Cavia porcellus	93.71	0.00e+00	1298.00
IUUC-Csa-023773	Chlorocebus sabaeus	99.10	0.00e+00	1388.00
IUUC-Cho-024302	Choloepus hoffmanni	92.09	0.00e+00	1088.00
IUUC-Cin-025384	Ciona intestinalis	33.87	5.00e-113	402.00
IUUC-Dre-027460	Danio rerio	51.72	0.00e+00	729.00
IUUC-Dno-029594	Dasypus novemcinctus	92.07	0.00e+00	1294.00
IUUC-Dor-030564	Dipodomys ordii	88.86	0.00e+00	814.00
IUUC-Dse-031179	Dothistroma septosporum	25.81	1.00e-33	138.00
IUUC-Dme-031603	Drosophila melanogaster	24.20	3.00e-51	196.00
IUUC-Ete-032655	Echinops telfairi	84.43	0.00e+00	1178.00
IUUC-Eca-033838	Equus caballus	93.56	0.00e+00	1317.00
IUUC-Eeu-034548	Erinaceus europaeus	88.77	0.00e+00	1242.00
IUUC-Fca-035715	Felis catus	94.16	0.00e+00	1330.00
IUUC-Fal-037394	Ficedula albicollis	58.57	0.00e+00	779.00
IUUC-Gmo-039235	Gadus morhua	47.31	0.00e+00	655.00
IUUC-Ggr-040043	Gaeumannomyces graminis	26.59	2.00e-29	124.00
IUUC-Gga-041172	Gallus gallus	61.34	0.00e+00	866.00
IUUC-Gac-042466	Gasterosteus aculeatus	52.69	0.00e+00	741.00
IUUC-Gma-044222	Glycine max	25.34	1.00e-41	164.00
IUUC-Ggo-045416	Gorilla gorilla	94.16	0.00e+00	1301.00
IUUC-Hsa-046115	Homo sapiens	97.90	0.00e+00	1366.00
IUUC-Hvu-047229	Hordeum vulgare	23.94	2.00e-43	171.00
IUUC-Itr-048015	Ictidomys tridecemlineatus	93.86	0.00e+00	1318.00
IUUC-Kpa-049370	Komagataella pastoris	20.58	3.00e-29	123.00
IUUC-Lch-050153	Latimeria chalumnae	58.59	0.00e+00	816.00
IUUC-Lpe-051220	Leersia perrieri	24.91	4.00e-47	183.00
IUUC-Loc-052617	Lepisosteus oculatus	53.55	0.00e+00	771.00
IUUC-Laf-053613	Loxodonta africana	90.42	0.00e+00	1270.00
IUUC-Meu-056800	Macropus eugenii	67.14	0.00e+00	805.00
IUUC-Mor-057245	Magnaporthe oryzae	27.00	3.00e-27	117.00
IUUC-Mpo-057446	Magnaporthe poae	27.93	8.00e-29	122.00
IUUC-Mtr-058748	Medicago truncatula	23.43	3.00e-43	170.00
IUUC-Mga-060018	Meleagris gallopavo	60.90	0.00e+00	826.00
IUUC-Mmr-061115	Microcebus murinus	94.91	0.00e+00	1310.00
IUUC-Mdo-062235	Monodelphis domestica	76.95	0.00e+00	1110.00
IUUC-Mmu-063158	Mus musculus	89.52	0.00e+00	1273.00
IUUC-Mac-065380	Musa acuminata	24.20	4.00e-50	193.00
IUUC-Mpu-065805	Mustela putorius furo	93.71	0.00e+00	1328.00
IUUC-Mlu-066951	Myotis lucifugus	91.47	0.00e+00	1290.00
IUUC-Nfi-068295	Neosartorya fischeri	25.77	1.00e-35	145.00
IUUC-Ncr-068880	Neurospora crassa	26.39	5.00e-35	143.00
IUUC-Nle-069657	Nomascus leucogenys	98.05	0.00e+00	1372.00
IUUC-Opr-070250	Ochotona princeps	90.87	0.00e+00	1271.00
IUUC-Ont-072642	Oreochromis niloticus	51.42	0.00e+00	694.00
IUUC-Ocu-074741	Oryctolagus cuniculus	93.71	0.00e+00	1316.00
IUUC-Oba-074974	Oryza barthii	24.66	5.00e-47	182.00
IUUC-Obr-076586	Oryza brachyantha	25.15	2.00e-44	173.00
IUUC-Ogl-077782	Oryza glaberrima	24.81	2.00e-50	194.00
IUUC-Ogu-078333	Oryza glumaepatula	24.97	3.00e-46	180.00
IUUC-Oin-079852	Oryza indica	23.93	2.00e-45	177.00
IUUC-Olo-080370	Oryza longistaminata	26.39	2.00e-41	164.00
IUUC-Ome-081442	Oryza meridionalis	23.54	3.00e-43	170.00
IUUC-Oni-082341	Oryza nivara	24.71	5.00e-45	176.00
IUUC-Opu-083824	Oryza punctata	23.52	2.00e-46	181.00
IUUC-Oru-084827	Oryza rufipogon	24.66	6.00e-47	182.00
IUUC-Osa-085742	Oryza sativa	23.93	1.00e-45	177.00
IUUC-Ola-086466	Oryzias latipes	53.12	0.00e+00	720.00
IUUC-Olu-087761	Ostreococcus lucimarinus	25.91	1.00e-49	191.00
IUUC-Oga-088721	Otolemur garnettii	84.34	0.00e+00	1147.00
IUUC-Oar-089532	Ovis aries	92.07	0.00e+00	1301.00
IUUC-Ptr-091604	Pan troglodytes	97.90	0.00e+00	1368.00
IUUC-Pan-092060	Papio anubis	98.92	0.00e+00	764.00
IUUC-Psi-093070	Pelodiscus sinensis	62.39	0.00e+00	847.00
IUUC-Pma-094201	Petromyzon marinus	48.39	4.00e-132	464.00
IUUC-Ppa-095599	Physcomitrella patens	28.53	1.00e-31	132.00
IUUC-Pfo-097207	Poecilia formosa	50.67	0.00e+00	696.00
IUUC-Pab-097746	Pongo abelii	97.90	0.00e+00	1368.00
IUUC-Pop-099669	Populus trichocarpa	24.69	1.00e-53	204.00
IUUC-Pca-100562	Procavia capensis	83.79	0.00e+00	953.00
IUUC-Ppe-101747	Prunus persica	24.09	7.00e-48	185.00
IUUC-Pva-103054	Pteropus vampyrus	93.11	0.00e+00	1321.00
IUUC-Pte-104064	Pyrenophora teres	25.06	2.00e-25	111.00
IUUC-Pyt-104595	Pyrenophora triticirepentis	25.93	2.00e-27	117.00
IUUC-Rno-105155	Rattus norvegicus	90.57	0.00e+00	1286.00
IUUC-Sce-106369	Saccharomyces cerevisiae	23.59	5.00e-40	159.00
IUUC-Sha-107149	Sarcophilus harrisii	76.05	0.00e+00	1098.00
IUUC-Sja-107777	Schizosaccharomyces japonicus	28.21	8.00e-61	228.00
IUUC-Spo-108372	Schizosaccharomyces pombe	29.10	7.00e-67	248.00
IUUC-Ssl-108650	Sclerotinia sclerotiorum	25.93	7.00e-37	149.00
IUUC-Smo-108851	Selaginella moellendorffii	23.54	3.00e-47	183.00
IUUC-Sit-110454	Setaria italica	25.00	3.00e-47	183.00
IUUC-Sly-111875	Solanum lycopersicum	24.69	1.00e-50	194.00
IUUC-Stu-112275	Solanum tuberosum	23.83	1.00e-44	174.00
IUUC-Sar-113254	Sorex araneus	77.50	0.00e+00	691.00
IUUC-Sbi-114624	Sorghum bicolor	24.92	9.00e-46	178.00
IUUC-Sre-114985	Sporisorium reilianum	20.89	1.00e-14	75.50
IUUC-Tgu-117407	Taeniopygia guttata	59.71	3.00e-139	488.00
IUUC-Tru-118733	Takifugu rubripes	47.46	0.00e+00	662.00
IUUC-Tsy-119213	Tarsius syrichta	84.52	0.00e+00	1068.00
IUUC-Tni-120894	Tetraodon nigroviridis	46.84	4.00e-89	321.00
IUUC-Tca-121606	Theobroma cacao	23.97	5.00e-43	169.00
IUUC-Tre-121958	Trichoderma reesei	25.70	2.00e-33	137.00
IUUC-Tvi-122290	Trichoderma virens	26.07	3.00e-34	140.00
IUUC-Tae-125538	Triticum aestivum	25.35	2.00e-48	187.00
IUUC-Tme-126995	Tuber melanosporum	24.88	5.00e-29	123.00
IUUC-Tbe-127605	Tupaia belangeri	89.08	7.00e-58	218.00
IUUC-Ttr-128720	Tursiops truncatus	91.77	0.00e+00	1290.00
IUUC-Uma-129564	Ustilago maydis	22.22	2.00e-13	71.60
IUUC-Vpa-130412	Vicugna pacos	92.98	3.00e-128	452.00
IUUC-Vvi-131256	Vitis vinifera	25.74	1.00e-48	188.00
IUUC-Xtr-131828	Xenopus tropicalis	54.17	0.00e+00	763.00
IUUC-Xma-133394	Xiphophorus maculatus	50.97	0.00e+00	700.00
IUUC-Yli-134565	Yarrowia lipolytica	28.22	1.00e-31	131.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence