iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107690

Ensembl Protein ID

EEB05557

UniProt Accession

B6JW06; B6JW06_SCHJY

Genbank Protein ID

EEB05557.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

KE651166

Gene Name

SJAG_00573

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_00573	EEB05557	EEB05557

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-73	245.6	232	546

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflld 101
           +GlkN+g+tCYmNS+LQ+L++++ +r+ +++     ++ +n ++p+ +++ +lq++f +l +++++ vs++el++++++ +  f++++q+D+qEf ++l d
   Q: 232  VGLKNQGATCYMNSLLQSLYFTNVFRRTVFT-----IPTQN-DSPTDSVAYALQRCFYNL-QHESEPVSTTELTQSFGWNS--FDSFMQHDVQEFNRVLQD 323
           6******************************.....55554.68999*************.9999*************655..99**************** PP
   S: 102  qleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeeleg 202
           +le+++                          k +  +s ++d+F g++ks ikc + d +ssr e+f+d++l+v+g +     +l++++++  + e+l+g
   Q: 324  NLEKKM--------------------------KGTPVDSALNDIFVGKIKSYIKCIDVDYESSRVEDFWDVQLNVKGMK-----NLEESFRDAIQVETLTG 393
           ******..........................7899*******************************************.....9**************** PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknek 303
           +nkyy e   ++q+a k + ++++P+vL l+LkRf ++  +++  kin++ efple+dl+p+++++ +k+ e++ Y L++v+vH G l++GHY+a++k + 
   Q: 394  DNKYYAEGH-GLQDAHKGMLFESFPDVLQLQLKRFDYDMMRDMMVKINDRHEFPLEIDLEPYLSESADKS-ESHVYALHGVLVHGGDLHGGHYYALIKPTA 492
           *****9986.79*****************************************************77665.7**************************976 PP
   S: 304  gk.WllfdDskVtevkeeevleetg...................staYvlfYkr 337
           ++ W++fdD++Vt  + +evle++                     +aY+l+Y r
   Q: 493  DSgWFKFDDDRVTRATLKEVLEDNFggeakvrhknyignpfkrfMNAYMLVYFR 546
           667*******************8879**************************66 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MDANDKHESE QPSLESSGME LDESSEAALR ADDFDEIYNT LVDEQPELEE ETHGHYTWLI 60
ENWDQLEEKV YSPIFTIGET NWRILLFPKG CNQGEYTSVF LEYLAPAKVA MIEQAEAEKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCACCAAG TCAACCCTCA GCTTGTCCTT AACCTACTGT TAACCAGCAC AATTGACAGA 60
GACAGAGACT ATTTGCTTAG GCAGTAAGTG ATATACGAGT TATTTAGCCA ATTTACGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF14533--USP7_C2
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000791	Aegilops tauschii	38.87	2.00e-128	451.00
IUUC-Aml-002408	Ailuropoda melanoleuca	33.09	4.00e-146	510.00
IUUC-Atr-003067	Amborella trichopoda	34.23	1.00e-116	412.00
IUUC-Apl-003558	Anas platyrhynchos	33.33	9.00e-155	539.00
IUUC-Aca-004518	Anolis carolinensis	31.77	2.00e-147	514.00
IUUC-Aly-006453	Arabidopsis lyrata	34.79	4.00e-151	527.00
IUUC-Ath-006591	Arabidopsis thaliana	35.25	2.00e-148	518.00
IUUC-Ago-007849	Ashbya gossypii	36.83	0.00e+00	652.00
IUUC-Acl-008327	Aspergillus clavatus	40.89	0.00e+00	826.00
IUUC-Afl-008491	Aspergillus flavus	41.44	0.00e+00	820.00
IUUC-Afu-008804	Aspergillus fumigatus	41.70	0.00e+00	803.00
IUUC-Ani-009257	Aspergillus nidulans	31.66	1.00e-39	158.00
IUUC-Ang-009776	Aspergillus niger	41.18	0.00e+00	816.00
IUUC-Aor-009998	Aspergillus oryzae	40.83	0.00e+00	792.00
IUUC-Ate-010428	Aspergillus terreus	41.38	0.00e+00	827.00
IUUC-Ame-010903	Astyanax mexicanus	31.96	4.00e-149	520.00
IUUC-Bgr-012132	Blumeria graminis	38.24	0.00e+00	764.00
IUUC-Bta-013192	Bos taurus	32.94	8.00e-147	512.00
IUUC-Bci-013924	Botrytis cinerea	40.78	0.00e+00	809.00
IUUC-Bdi-014329	Brachypodium distachyon	35.47	3.00e-148	517.00
IUUC-Bol-016114	Brassica oleracea	34.49	3.00e-147	514.00
IUUC-Bra-016714	Brassica rapa	34.36	2.00e-146	511.00
IUUC-Cel-018219	Caenorhabditis elegans	42.08	8.00e-96	343.00
IUUC-Cja-019006	Callithrix jacchus	32.75	6.00e-147	513.00
IUUC-Cfa-020361	Canis familiaris	32.85	3.00e-146	511.00
IUUC-Cpo-022320	Cavia porcellus	33.18	5.00e-146	509.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	42.37	2.00e-101	360.00
IUUC-Csa-024050	Chlorocebus sabaeus	32.85	4.00e-146	510.00
IUUC-Cho-024434	Choloepus hoffmanni	29.56	7.00e-78	283.00
IUUC-Cin-025689	Ciona intestinalis	31.69	4.00e-145	506.00
IUUC-Csv-025963	Ciona savignyi	31.65	8.00e-140	489.00
IUUC-Cgl-026650	Colletotrichum gloeosporioides	39.48	0.00e+00	784.00
IUUC-Cne-026968	Cryptococcus neoformans	39.98	0.00e+00	828.00
IUUC-Cme-027103	Cyanidioschyzon merolae	36.44	1.00e-113	402.00
IUUC-Dre-028510	Danio rerio	32.30	5.00e-151	526.00
IUUC-Dno-029696	Dasypus novemcinctus	33.18	7.00e-145	506.00
IUUC-Dor-030611	Dipodomys ordii	48.21	5.00e-71	260.00
IUUC-Dse-031433	Dothistroma septosporum	38.36	0.00e+00	759.00
IUUC-Dme-031583	Drosophila melanogaster	31.92	4.00e-130	457.00
IUUC-Ete-033191	Echinops telfairi	32.54	5.00e-140	490.00
IUUC-Eca-034122	Equus caballus	33.27	4.00e-147	513.00
IUUC-Eeu-035292	Erinaceus europaeus	34.69	1.00e-58	219.00
IUUC-Fca-036377	Felis catus	32.85	1.00e-146	512.00
IUUC-Fal-036964	Ficedula albicollis	33.07	3.00e-156	544.00
IUUC-Fox-037695	Fusarium oxysporum	39.24	0.00e+00	781.00
IUUC-Fso-038084	Fusarium solani	40.16	0.00e+00	776.00
IUUC-Gmo-038644	Gadus morhua	32.38	8.00e-151	526.00
IUUC-Ggr-040029	Gaeumannomyces graminis	39.37	0.00e+00	774.00
IUUC-Gga-040944	Gallus gallus	33.30	7.00e-156	542.00
IUUC-Gac-041740	Gasterosteus aculeatus	32.55	4.00e-152	530.00
IUUC-Gma-044078	Glycine max	35.28	6.00e-153	533.00
IUUC-Ggo-044947	Gorilla gorilla	33.09	6.00e-146	509.00
IUUC-Hsa-046278	Homo sapiens	33.09	6.00e-146	509.00
IUUC-Hvu-047749	Hordeum vulgare	35.81	1.00e-136	478.00
IUUC-Itr-047904	Ictidomys tridecemlineatus	34.63	3.00e-138	484.00
IUUC-Kpa-049121	Komagataella pastoris	46.68	7.00e-169	586.00
IUUC-Lch-049847	Latimeria chalumnae	33.39	3.00e-155	540.00
IUUC-Lpe-051543	Leersia perrieri	34.41	2.00e-143	501.00
IUUC-Loc-052234	Lepisosteus oculatus	39.03	3.00e-129	454.00
IUUC-Lma-053169	Leptosphaeria maculans	39.16	0.00e+00	803.00
IUUC-Laf-053566	Loxodonta africana	33.18	4.00e-146	510.00
IUUC-Mcc-055549	Macaca mulatta	32.85	5.00e-146	509.00
IUUC-Meu-056887	Macropus eugenii	25.70	1.00e-54	206.00
IUUC-Mor-057149	Magnaporthe oryzae	39.77	0.00e+00	773.00
IUUC-Mpo-057536	Magnaporthe poae	39.64	0.00e+00	773.00
IUUC-Mtr-058630	Medicago truncatula	34.63	6.00e-148	516.00
IUUC-Mla-058899	Melampsora laricipopulina	39.38	0.00e+00	772.00
IUUC-Mga-060148	Meleagris gallopavo	33.30	7.00e-156	542.00
IUUC-Mvi-060207	Microbotryum violaceum	39.80	0.00e+00	800.00
IUUC-Mmr-060946	Microcebus murinus	32.85	1.00e-146	511.00
IUUC-Mdo-062079	Monodelphis domestica	33.63	4.00e-133	467.00
IUUC-Mmu-063678	Mus musculus	33.00	1.00e-144	505.00
IUUC-Mac-064786	Musa acuminata	34.88	3.00e-149	520.00
IUUC-Mpu-066744	Mustela putorius furo	32.76	3.00e-146	510.00
IUUC-Mlu-067949	Myotis lucifugus	32.94	1.00e-146	511.00
IUUC-Nfi-068342	Neosartorya fischeri	41.35	0.00e+00	798.00
IUUC-Ncr-068818	Neurospora crassa	40.12	0.00e+00	804.00
IUUC-Nle-070064	Nomascus leucogenys	33.09	6.00e-146	509.00
IUUC-Opr-071001	Ochotona princeps	33.17	8.00e-128	449.00
IUUC-Ont-072095	Oreochromis niloticus	32.20	2.00e-149	521.00
IUUC-Oan-073483	Ornithorhynchus anatinus	33.18	5.00e-145	506.00
IUUC-Ocu-073967	Oryctolagus cuniculus	32.85	1.00e-144	505.00
IUUC-Oba-075312	Oryza barthii	33.45	9.00e-137	479.00
IUUC-Obr-076857	Oryza brachyantha	34.78	1.00e-147	515.00
IUUC-Ogl-077038	Oryza glaberrima	34.66	1.00e-146	512.00
IUUC-Ogu-079038	Oryza glumaepatula	32.74	2.00e-135	474.00
IUUC-Oin-079513	Oryza indica	34.75	2.00e-138	485.00
IUUC-Olo-081067	Oryza longistaminata	33.21	1.00e-132	465.00
IUUC-Ome-081879	Oryza meridionalis	34.20	2.00e-138	485.00
IUUC-Oni-082978	Oryza nivara	32.12	5.00e-129	453.00
IUUC-Opu-083199	Oryza punctata	34.11	4.00e-140	490.00
IUUC-Oru-084739	Oryza rufipogon	32.53	3.00e-129	454.00
IUUC-Osa-085418	Oryza sativa	35.62	2.00e-135	474.00
IUUC-Ola-086640	Oryzias latipes	32.40	5.00e-150	523.00
IUUC-Olu-087874	Ostreococcus lucimarinus	30.99	3.00e-117	414.00
IUUC-Oga-089059	Otolemur garnettii	30.39	1.00e-121	428.00
IUUC-Oar-089710	Ovis aries	32.94	5.00e-147	513.00
IUUC-Ptr-091334	Pan troglodytes	33.09	6.00e-146	509.00
IUUC-Pan-091717	Papio anubis	33.09	1.00e-145	508.00
IUUC-Psi-093933	Pelodiscus sinensis	33.06	4.00e-154	537.00
IUUC-Pma-094648	Petromyzon marinus	32.89	3.00e-148	517.00
IUUC-Pno-095020	Phaeosphaeria nodorum	38.90	0.00e+00	743.00
IUUC-Ppa-095922	Physcomitrella patens	34.06	1.00e-148	518.00
IUUC-Pfo-096181	Poecilia formosa	32.38	1.00e-149	522.00
IUUC-Pab-098231	Pongo abelii	31.53	2.00e-132	464.00
IUUC-Pop-100083	Populus trichocarpa	35.14	3.00e-151	527.00
IUUC-Pca-100543	Procavia capensis	34.89	2.00e-87	315.00
IUUC-Ppe-101523	Prunus persica	35.00	4.00e-147	513.00
IUUC-Pva-102472	Pteropus vampyrus	32.85	1.00e-139	488.00
IUUC-Pgr-103463	Puccinia graminis	39.68	0.00e+00	768.00
IUUC-Ptt-103716	Puccinia triticina	39.58	0.00e+00	730.00
IUUC-Pte-104360	Pyrenophora teres	40.19	0.00e+00	759.00
IUUC-Pyt-104581	Pyrenophora triticirepentis	39.83	0.00e+00	754.00
IUUC-Rno-105816	Rattus norvegicus	33.09	8.00e-146	509.00
IUUC-Sce-106230	Saccharomyces cerevisiae	44.70	1.00e-156	545.00
IUUC-Sha-107439	Sarcophilus harrisii	32.58	6.00e-146	509.00
IUUC-Spo-108019	Schizosaccharomyces pombe	56.78	0.00e+00	1242.00
IUUC-Smo-109308	Selaginella moellendorffii	34.72	5.00e-147	513.00
IUUC-Sit-110367	Setaria italica	34.77	1.00e-151	528.00
IUUC-Sly-111008	Solanum lycopersicum	34.59	1.00e-145	509.00
IUUC-Stu-112387	Solanum tuberosum	35.53	5.00e-154	536.00
IUUC-Sar-113685	Sorex araneus	32.73	2.00e-144	504.00
IUUC-Sbi-114424	Sorghum bicolor	34.65	3.00e-144	504.00
IUUC-Sre-115156	Sporisorium reilianum	42.07	0.00e+00	843.00
IUUC-Ssc-116297	Sus scrofa	32.94	9.00e-147	512.00
IUUC-Tgu-116767	Taeniopygia guttata	32.93	6.00e-155	539.00
IUUC-Tru-118208	Takifugu rubripes	32.46	1.00e-151	528.00
IUUC-Tsy-119277	Tarsius syrichta	38.02	2.00e-63	236.00
IUUC-Tni-119890	Tetraodon nigroviridis	32.63	7.00e-151	526.00
IUUC-Tca-121630	Theobroma cacao	34.80	5.00e-150	523.00
IUUC-Tre-122169	Trichoderma reesei	39.38	0.00e+00	775.00
IUUC-Tvi-122600	Trichoderma virens	39.61	0.00e+00	792.00
IUUC-Tae-125264	Triticum aestivum	34.49	7.00e-148	516.00
IUUC-Tur-126287	Triticum urartu	32.75	9.00e-137	479.00
IUUC-Tme-127045	Tuber melanosporum	40.40	0.00e+00	836.00
IUUC-Tbe-127861	Tupaia belangeri	34.10	1.00e-51	196.00
IUUC-Ttr-129161	Tursiops truncatus	32.85	4.00e-144	503.00
IUUC-Uma-129535	Ustilago maydis	42.04	0.00e+00	851.00
IUUC-Vda-129708	Verticillium dahliae	40.26	0.00e+00	827.00
IUUC-Vpa-130141	Vicugna pacos	33.86	6.00e-54	204.00
IUUC-Vvi-131048	Vitis vinifera	34.79	3.00e-148	517.00
IUUC-Xtr-132073	Xenopus tropicalis	32.32	3.00e-148	517.00
IUUC-Xma-133949	Xiphophorus maculatus	32.47	2.00e-149	521.00
IUUC-Yli-134527	Yarrowia lipolytica	37.97	0.00e+00	737.00
IUUC-Zma-135855	Zea mays	35.26	4.00e-145	507.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence