iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	9311911

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	0.082	11.9	177	207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf......kdgplvlpCgHvfhadCl 26
           C +C e++      ++  + l CgH+ h++Cl
   Q: 177  CTLCDEPIsnrrkgEK-IIELACGHLSHQECL 207
           8999777765555333.66688*********8 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Present with 1900 molecules/cell in log phase SD medium.

Protein Sequence
(Fasta)

MMETPTDNIV SPFHNFGSST QYSGTLSRTP NQIIELEKPS TLSPLSRGKK WTEKLARFQR 60
SSAKKKRFSP SPISSSTFSF SPKSRVTSSN SSGNEDGNLM NTPSTVSTDY LPQHPHRTSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGGAAA CTCCTACAGA CAATATAGTT TCCCCTTTTC ACAATTTTGG TAGCTCGACA 60
CAATATAGTG GTACCTTGTC GAGAACTCCC AACCAAATAA TAGAGCTAGA GAAGCCCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0589--Pheromone response
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR021651--Ste5_Fus-binding
IPR021106--Ste5_Fus3-bd_dom
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF11610--Ste5
PF12194--Ste5_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043332--C:mating projection tip
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005078--F:MAP-kinase scaffold activity
GO:0005546--F:phosphatidylinositol-4,5-bisphosphate binding
GO:0001403--P:invasive growth in response to glucose limitation
GO:0043409--P:negative regulation of MAPK cascade
GO:0000750--P:pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001934--P:positive regulation of protein phosphorylation
GO:0010525--P:regulation of transposition, RNA-mediated

KEGG

sce:YDR103W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001153	Aegilops tauschii	27.94	1.20e-02	33.10
IUUC-Ago-007778	Ashbya gossypii	34.98	4.00e-57	214.00
IUUC-Acl-008023	Aspergillus clavatus	30.23	3.00e-07	48.90
IUUC-Afu-008768	Aspergillus fumigatus	27.91	2.00e-06	46.60
IUUC-Ani-009160	Aspergillus nidulans	27.91	4.00e-07	48.90
IUUC-Bgr-012106	Blumeria graminis	37.21	1.00e-08	53.90
IUUC-Bci-013996	Botrytis cinerea	38.89	1.00e-07	50.40
IUUC-Cgl-026467	Colletotrichum gloeosporioides	32.56	3.00e-07	48.90
IUUC-Cne-026825	Cryptococcus neoformans	31.15	5.00e-04	38.90
IUUC-Dre-027550	Danio rerio	27.78	1.90e-02	32.70
IUUC-Dno-029720	Dasypus novemcinctus	42.86	7.00e-04	34.70
IUUC-Dse-031363	Dothistroma septosporum	41.03	3.00e-09	55.50
IUUC-Fso-038109	Fusarium solani	37.10	3.30e-02	32.00
IUUC-Ggr-040101	Gaeumannomyces graminis	38.89	7.00e-07	48.10
IUUC-Kpa-049193	Komagataella pastoris	33.77	1.00e-07	50.10
IUUC-Mor-056974	Magnaporthe oryzae	38.89	2.00e-07	50.10
IUUC-Mla-059003	Melampsora laricipopulina	39.39	2.90e-01	28.10
IUUC-Mmu-063144	Mus musculus	29.07	1.00e-04	40.00
IUUC-Ocu-073929	Oryctolagus cuniculus	26.81	3.00e-03	37.00
IUUC-Pno-094846	Phaeosphaeria nodorum	37.21	9.00e-08	50.10
IUUC-Ppe-101656	Prunus persica	26.96	3.00e-05	38.50
IUUC-Rno-105769	Rattus norvegicus	27.78	1.00e-03	36.60
IUUC-Sit-110693	Setaria italica	29.09	4.00e-04	37.40
IUUC-Sar-113116	Sorex araneus	27.59	2.00e-03	35.80
IUUC-Sbi-114879	Sorghum bicolor	28.30	5.00e-03	33.50
IUUC-Tca-121669	Theobroma cacao	23.64	8.00e-04	36.20
IUUC-Tre-122200	Trichoderma reesei	32.56	5.00e-07	48.10
IUUC-Tae-125630	Triticum aestivum	29.31	2.00e-05	42.00
IUUC-Tur-126185	Triticum urartu	25.22	6.00e-05	40.40
IUUC-Tme-127086	Tuber melanosporum	28.33	2.00e-07	49.70
IUUC-Tbe-128054	Tupaia belangeri	37.50	1.30e-02	32.70
IUUC-Vda-129681	Verticillium dahliae	30.77	9.00e-07	47.40
IUUC-Vpa-130826	Vicugna pacos	36.36	1.00e-02	33.50
IUUC-Vvi-131328	Vitis vinifera	27.16	9.00e-03	33.90
IUUC-Yli-134606	Yarrowia lipolytica	33.75	1.00e-06	46.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence