iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090293

Ensembl Protein ID

ENSOARP00000010829.1

UniProt Accession

W5PK58; W5PK58_SHEEP

Genbank Protein ID

ENSOARP00000010829

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01045008

Gene Name

UBA3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010086.1	ENSOART00000010987.1	ENSOARP00000010829.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.60e-95	319.8	76	270

Active Site

Position(s)	Description	Evidence
252	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 15   klksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnvea.....heesit 98
            l+++kvl++GagglGcEllKnL+l+G+++i+v+Dmdt++vsnlnrqFLfr++dvg++KAevaae+l+++ p++nv++     h ++i+
   Q: 76   LLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRIPNCNVVPypfdkHFNKIQ 164
           589************************************************************************98744444788888 PP
   S: 99   eleeeivFfkkfdvVvlaldnrearrkvnrlclna............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPf 173
           + +++  F+++f+++v++ld++ arr++n +++++             vpli++gt+G++G++rvi++g+t+c++c+   +ppq+++P+
   Q: 165  DFNDT--FYRQFHIIVCGLDSIIARRWINGMLISLlnyedgvldpssIVPLIDGGTEGFKGNARVILPGMTACIECTLelYPPQVNFPM 251
           88888..***************************9****************************************************** PP
   S: 174  ctlketpnaaehtiewavl 192
           ct++++p+ +eh+ie++++
   Q: 252  CTIASMPRLPEHCIEYVRI 270
           ****************933 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

VCSKRFLFFL VAYIFCSKAV YRIDWAVCSV QMAVDGGCGD TGDWEGRWNH VKKFLERSGP 60
FTHPDFEPST ESLQFLLDTC KVLVIGAGGL GCELLKNLAL SGFRQIHVID MDTIDVSNLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATGTTCTA AAAGGTTTGT AGATGGTATT GCCTACCTGT GATGTAATTA TAATCTAAAA 60
CTTTGATTGT GTTTAGTGGC AATAGAAGCC ACCTTATAGT CCTAAGAGAT TCTTTTTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0005634--C:nucleus
GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0007113--P:endomitotic cell cycle
GO:0045116--P:protein neddylation
GO:0051726--P:regulation of cell cycle

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	48.10	5.00e-79	288.00
IUUC-Aml-001578	Ailuropoda melanoleuca	97.54	0.00e+00	909.00
IUUC-Atr-002591	Amborella trichopoda	49.75	2.00e-89	322.00
IUUC-Apl-003671	Anas platyrhynchos	90.16	0.00e+00	853.00
IUUC-Aca-004749	Anolis carolinensis	90.05	0.00e+00	818.00
IUUC-Aly-005747	Arabidopsis lyrata	47.06	3.00e-95	342.00
IUUC-Ath-006623	Arabidopsis thaliana	47.30	4.00e-95	341.00
IUUC-Ago-007934	Ashbya gossypii	44.38	1.00e-71	263.00
IUUC-Acl-008047	Aspergillus clavatus	49.31	2.00e-120	425.00
IUUC-Afl-008615	Aspergillus flavus	43.76	6.00e-79	287.00
IUUC-Afu-008996	Aspergillus fumigatus	50.23	1.00e-113	402.00
IUUC-Ani-009281	Aspergillus nidulans	42.79	1.00e-82	300.00
IUUC-Ang-009539	Aspergillus niger	50.23	1.00e-110	393.00
IUUC-Aor-010151	Aspergillus oryzae	48.12	5.00e-109	387.00
IUUC-Ate-010502	Aspergillus terreus	50.47	2.00e-112	399.00
IUUC-Ame-011837	Astyanax mexicanus	85.27	0.00e+00	777.00
IUUC-Bgr-012068	Blumeria graminis	49.88	6.00e-112	397.00
IUUC-Bta-013003	Bos taurus	98.88	0.00e+00	912.00
IUUC-Bci-013983	Botrytis cinerea	53.13	2.00e-122	432.00
IUUC-Bdi-014429	Brachypodium distachyon	48.40	2.00e-86	312.00
IUUC-Bol-015813	Brassica oleracea	48.04	2.00e-87	316.00
IUUC-Bra-018023	Brassica rapa	47.30	2.00e-84	306.00
IUUC-Cel-018684	Caenorhabditis elegans	52.89	9.00e-127	446.00
IUUC-Cja-019200	Callithrix jacchus	97.10	0.00e+00	898.00
IUUC-Cfa-021038	Canis familiaris	98.43	0.00e+00	912.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	48.45	1.00e-105	376.00
IUUC-Csa-024079	Chlorocebus sabaeus	97.32	0.00e+00	907.00
IUUC-Cho-025052	Choloepus hoffmanni	90.16	0.00e+00	817.00
IUUC-Cin-025113	Ciona intestinalis	67.79	2.00e-179	621.00
IUUC-Csv-026231	Ciona savignyi	65.55	8.00e-179	619.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	50.80	5.00e-123	434.00
IUUC-Cne-026850	Cryptococcus neoformans	47.91	6.00e-107	380.00
IUUC-Cme-027275	Cyanidioschyzon merolae	36.27	3.00e-67	248.00
IUUC-Dre-028751	Danio rerio	85.04	0.00e+00	788.00
IUUC-Dno-029571	Dasypus novemcinctus	97.76	0.00e+00	906.00
IUUC-Dor-030395	Dipodomys ordii	95.97	0.00e+00	876.00
IUUC-Dse-031329	Dothistroma septosporum	45.45	5.00e-103	367.00
IUUC-Dme-031776	Drosophila melanogaster	63.53	3.00e-159	554.00
IUUC-Ete-032894	Echinops telfairi	75.43	1.00e-68	253.00
IUUC-Eca-034389	Equus caballus	98.21	0.00e+00	908.00
IUUC-Eeu-035152	Erinaceus europaeus	85.50	0.00e+00	684.00
IUUC-Fca-036032	Felis catus	97.99	0.00e+00	912.00
IUUC-Fal-037506	Ficedula albicollis	89.26	0.00e+00	847.00
IUUC-Fox-037871	Fusarium oxysporum	53.14	6.00e-109	387.00
IUUC-Fso-038350	Fusarium solani	51.49	1.00e-120	426.00
IUUC-Gmo-039246	Gadus morhua	82.59	0.00e+00	755.00
IUUC-Ggr-039859	Gaeumannomyces graminis	52.40	3.00e-118	418.00
IUUC-Gga-040843	Gallus gallus	88.39	0.00e+00	829.00
IUUC-Gac-042601	Gasterosteus aculeatus	83.71	0.00e+00	773.00
IUUC-Gma-042744	Glycine max	50.38	7.00e-87	314.00
IUUC-Ggo-044788	Gorilla gorilla	97.32	0.00e+00	900.00
IUUC-Hsa-045849	Homo sapiens	97.76	0.00e+00	908.00
IUUC-Hvu-047819	Hordeum vulgare	50.28	2.00e-80	292.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	97.32	0.00e+00	903.00
IUUC-Kpa-049393	Komagataella pastoris	53.59	6.00e-101	360.00
IUUC-Lch-049471	Latimeria chalumnae	89.96	0.00e+00	825.00
IUUC-Lpe-051297	Leersia perrieri	47.74	2.00e-95	343.00
IUUC-Loc-052910	Lepisosteus oculatus	87.50	0.00e+00	803.00
IUUC-Lma-053181	Leptosphaeria maculans	49.43	2.00e-119	422.00
IUUC-Laf-054314	Loxodonta africana	98.88	0.00e+00	923.00
IUUC-Mcc-054870	Macaca mulatta	97.76	0.00e+00	907.00
IUUC-Meu-056574	Macropus eugenii	79.02	6.00e-131	460.00
IUUC-Mor-056919	Magnaporthe oryzae	53.56	4.00e-122	431.00
IUUC-Mpo-057614	Magnaporthe poae	53.92	7.00e-113	400.00
IUUC-Mtr-058110	Medicago truncatula	50.13	2.00e-87	316.00
IUUC-Mla-058949	Melampsora laricipopulina	52.66	8.00e-116	410.00
IUUC-Mga-059455	Meleagris gallopavo	89.93	0.00e+00	848.00
IUUC-Mvi-060270	Microbotryum violaceum	50.34	1.00e-117	416.00
IUUC-Mmr-061155	Microcebus murinus	94.56	0.00e+00	849.00
IUUC-Mdo-062037	Monodelphis domestica	95.14	0.00e+00	853.00
IUUC-Mmu-063670	Mus musculus	97.53	0.00e+00	904.00
IUUC-Mac-064711	Musa acuminata	48.28	2.00e-85	309.00
IUUC-Mpu-066734	Mustela putorius furo	97.78	0.00e+00	905.00
IUUC-Mlu-067068	Myotis lucifugus	97.45	0.00e+00	870.00
IUUC-Nfi-068349	Neosartorya fischeri	49.88	5.00e-113	400.00
IUUC-Ncr-068626	Neurospora crassa	52.35	5.00e-106	377.00
IUUC-Nle-069366	Nomascus leucogenys	89.38	0.00e+00	811.00
IUUC-Opr-070993	Ochotona princeps	91.54	1.00e-67	250.00
IUUC-Ont-072196	Oreochromis niloticus	84.41	0.00e+00	765.00
IUUC-Oan-073511	Ornithorhynchus anatinus	92.62	0.00e+00	871.00
IUUC-Ocu-073773	Oryctolagus cuniculus	97.32	0.00e+00	906.00
IUUC-Oba-075726	Oryza barthii	44.26	7.00e-84	304.00
IUUC-Obr-076286	Oryza brachyantha	46.79	2.00e-92	332.00
IUUC-Ogu-078473	Oryza glumaepatula	44.26	7.00e-84	304.00
IUUC-Oin-079393	Oryza indica	48.89	8.00e-98	350.00
IUUC-Olo-080446	Oryza longistaminata	45.84	2.00e-87	316.00
IUUC-Ome-081737	Oryza meridionalis	46.44	3.00e-87	315.00
IUUC-Oni-082853	Oryza nivara	44.26	7.00e-84	304.00
IUUC-Opu-083590	Oryza punctata	47.98	3.00e-97	348.00
IUUC-Oru-084184	Oryza rufipogon	44.26	7.00e-84	304.00
IUUC-Osa-085402	Oryza sativa	48.89	8.00e-98	350.00
IUUC-Ola-086615	Oryzias latipes	78.08	0.00e+00	709.00
IUUC-Olu-087738	Ostreococcus lucimarinus	47.80	1.00e-91	330.00
IUUC-Oga-088101	Otolemur garnettii	97.32	0.00e+00	905.00
IUUC-Ptr-090503	Pan troglodytes	97.76	0.00e+00	908.00
IUUC-Pan-092477	Papio anubis	95.33	0.00e+00	877.00
IUUC-Psi-093442	Pelodiscus sinensis	90.36	0.00e+00	850.00
IUUC-Pma-094247	Petromyzon marinus	80.22	0.00e+00	766.00
IUUC-Pno-094780	Phaeosphaeria nodorum	49.00	4.00e-113	401.00
IUUC-Ppa-095338	Physcomitrella patens	48.71	6.00e-114	404.00
IUUC-Pfo-097137	Poecilia formosa	84.63	0.00e+00	769.00
IUUC-Pab-098060	Pongo abelii	97.32	0.00e+00	869.00
IUUC-Pop-099470	Populus trichocarpa	46.84	4.00e-92	331.00
IUUC-Pca-100500	Procavia capensis	81.88	0.00e+00	728.00
IUUC-Ppe-102008	Prunus persica	48.10	1.00e-83	303.00
IUUC-Pva-103095	Pteropus vampyrus	97.21	9.00e-126	443.00
IUUC-Pgr-103666	Puccinia graminis	50.23	1.00e-113	403.00
IUUC-Ptt-103901	Puccinia triticina	50.70	3.00e-116	412.00
IUUC-Pte-104198	Pyrenophora teres	48.43	9.00e-118	416.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	47.76	1.00e-115	409.00
IUUC-Rno-105446	Rattus norvegicus	97.53	0.00e+00	903.00
IUUC-Sce-106355	Saccharomyces cerevisiae	42.01	4.00e-69	254.00
IUUC-Sha-106664	Sarcophilus harrisii	95.14	0.00e+00	854.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	42.76	1.00e-97	350.00
IUUC-Spo-108345	Schizosaccharomyces pombe	43.03	3.00e-96	345.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	48.60	3.00e-105	375.00
IUUC-Smo-109133	Selaginella moellendorffii	49.18	1.00e-113	403.00
IUUC-Sit-109724	Setaria italica	46.55	5.00e-89	321.00
IUUC-Sly-110916	Solanum lycopersicum	47.97	5.00e-93	334.00
IUUC-Stu-112236	Solanum tuberosum	47.72	1.00e-92	333.00
IUUC-Sar-113044	Sorex araneus	97.30	0.00e+00	811.00
IUUC-Sbi-114276	Sorghum bicolor	48.77	5.00e-89	321.00
IUUC-Sre-114963	Sporisorium reilianum	51.61	3.00e-117	415.00
IUUC-Ssc-116301	Sus scrofa	99.11	0.00e+00	925.00
IUUC-Tgu-117265	Taeniopygia guttata	89.04	0.00e+00	845.00
IUUC-Tru-117526	Takifugu rubripes	83.52	0.00e+00	760.00
IUUC-Tsy-119483	Tarsius syrichta	96.66	0.00e+00	838.00
IUUC-Tni-120363	Tetraodon nigroviridis	85.19	0.00e+00	751.00
IUUC-Tca-121731	Theobroma cacao	48.51	8.00e-87	313.00
IUUC-Tre-122221	Trichoderma reesei	52.62	1.00e-109	389.00
IUUC-Tvi-122352	Trichoderma virens	50.92	1.00e-121	429.00
IUUC-Tae-123864	Triticum aestivum	47.74	4.00e-88	318.00
IUUC-Tur-126070	Triticum urartu	45.12	1.00e-68	253.00
IUUC-Tme-127199	Tuber melanosporum	50.26	7.00e-108	383.00
IUUC-Tbe-128076	Tupaia belangeri	97.32	0.00e+00	905.00
IUUC-Ttr-128695	Tursiops truncatus	82.10	0.00e+00	740.00
IUUC-Uma-129638	Ustilago maydis	50.92	6.00e-117	414.00
IUUC-Vda-129963	Verticillium dahliae	51.25	8.00e-113	400.00
IUUC-Vpa-130637	Vicugna pacos	90.60	0.00e+00	818.00
IUUC-Vvi-131613	Vitis vinifera	47.85	9.00e-83	300.00
IUUC-Xtr-132924	Xenopus tropicalis	88.86	0.00e+00	809.00
IUUC-Xma-133356	Xiphophorus maculatus	84.63	0.00e+00	769.00
IUUC-Yli-134365	Yarrowia lipolytica	51.52	4.00e-109	388.00
IUUC-Zma-135941	Zea mays	44.39	2.00e-83	303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence