iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tur-126070

Ensembl Protein ID

TRIUR3_35263-P1

UniProt Accession

M8AKS5; M8AKS5_TRIUA

Genbank Protein ID

EMS65635.1

Protein Name

NEDD8-activating enzyme E1 catalytic subunit

Genbank Nucleotide ID

KD041793

Gene Name

TRIUR3_35263

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIUR3_35263	TRIUR3_35263-T1	TRIUR3_35263-P1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.10e-60	205.3	82	223

Active Site

Position(s)	Description	Evidence
204	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 65   raedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlaldnrearrkvnrlclna.............rvpliesgtlGl 145
           r +dvgk+KAevaa+++ e+++ vn+++h ++i+++e e  F+++f+++vl+ld++ear ++n++ +                +p++++gt+G+
   Q: 82   RIQDVGKPKAEVAAKRVMERVSGVNIVPHFCRIEDKELE--FYNQFQIIVLGLDSIEARSYINSVACGFleydaddkpvqetVKPMVDGGTEGF 173
           779*********************************999..***************************9************99*********** PP
   S: 146  lGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewavlf 193
           +G++rvii+g t c +c+    ppq+++P+ctl+etp++a h+ie+a+l+
   Q: 174  KGHARVIIPGTTPCFECNIwlFPPQVKFPLCTLAETPRTAAHCIEYAHLI 223
           ***********************************************444 PP

Organism

Triticum urartu

Protein Sequence
(Fasta)

MERTTGSGGG AGATGAGAAL ARGGGMMQTG EGARSAAARS TPAAEWPSTH LSWMGLLPAM 60
TGVGGAWRDA GVAIGETERA VRIQDVGKPK AEVAAKRVME RVSGVNIVPH FCRIEDKELE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAGGA CCACCGGCTC CGGTGGCGGA GCCGGAGCGA CCGGTGCCGG CGCTGCATTG 60
GCCCGGGGCG GCGGCATGAT GCAGACAGGG GAGGGAGCTC GCAGTGCCGC CGCCAGATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	98.89	0.00e+00	712.00
IUUC-Aml-001578	Ailuropoda melanoleuca	45.20	5.00e-78	284.00
IUUC-Atr-002591	Amborella trichopoda	76.19	9.00e-158	548.00
IUUC-Apl-003671	Anas platyrhynchos	45.82	1.00e-78	286.00
IUUC-Aca-004749	Anolis carolinensis	45.20	2.00e-78	285.00
IUUC-Aly-005747	Arabidopsis lyrata	73.11	2.00e-149	520.00
IUUC-Ath-006623	Arabidopsis thaliana	72.91	7.00e-148	516.00
IUUC-Ago-007934	Ashbya gossypii	34.57	2.00e-35	142.00
IUUC-Acl-008047	Aspergillus clavatus	46.86	7.00e-82	296.00
IUUC-Afl-008615	Aspergillus flavus	37.20	6.00e-48	183.00
IUUC-Afu-008996	Aspergillus fumigatus	47.80	8.00e-75	273.00
IUUC-Ani-009281	Aspergillus nidulans	48.10	6.00e-68	250.00
IUUC-Ang-009539	Aspergillus niger	47.00	5.00e-72	263.00
IUUC-Aor-010151	Aspergillus oryzae	46.37	8.00e-70	256.00
IUUC-Ate-010502	Aspergillus terreus	48.26	5.00e-72	263.00
IUUC-Ame-011837	Astyanax mexicanus	44.27	2.00e-69	255.00
IUUC-Bgr-012068	Blumeria graminis	48.28	4.00e-74	270.00
IUUC-Bta-013003	Bos taurus	45.82	3.00e-79	288.00
IUUC-Bci-013983	Botrytis cinerea	49.84	5.00e-74	270.00
IUUC-Bdi-014429	Brachypodium distachyon	94.18	0.00e+00	679.00
IUUC-Bol-015813	Brassica oleracea	77.03	3.00e-157	546.00
IUUC-Bra-017260	Brassica rapa	75.63	7.00e-155	539.00
IUUC-Cel-018684	Caenorhabditis elegans	46.91	3.00e-78	284.00
IUUC-Cja-019200	Callithrix jacchus	45.99	4.00e-78	284.00
IUUC-Cfa-021038	Canis familiaris	45.82	5.00e-79	287.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	56.10	2.00e-106	377.00
IUUC-Csa-024079	Chlorocebus sabaeus	45.51	3.00e-79	288.00
IUUC-Cho-025052	Choloepus hoffmanni	39.32	1.00e-60	225.00
IUUC-Cin-025113	Ciona intestinalis	46.46	2.00e-71	261.00
IUUC-Csv-026231	Ciona savignyi	45.23	5.00e-77	280.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	47.80	2.00e-73	268.00
IUUC-Cne-026850	Cryptococcus neoformans	44.34	6.00e-66	243.00
IUUC-Cme-027275	Cyanidioschyzon merolae	35.74	1.00e-55	209.00
IUUC-Dre-028751	Danio rerio	44.48	3.00e-69	254.00
IUUC-Dno-029571	Dasypus novemcinctus	45.51	7.00e-78	283.00
IUUC-Dor-030395	Dipodomys ordii	46.69	1.00e-79	289.00
IUUC-Dse-031329	Dothistroma septosporum	42.61	2.00e-66	245.00
IUUC-Dme-031776	Drosophila melanogaster	46.44	4.00e-74	271.00
IUUC-Eca-034389	Equus caballus	45.82	2.00e-79	288.00
IUUC-Eeu-035152	Erinaceus europaeus	39.38	4.00e-57	214.00
IUUC-Fca-036032	Felis catus	45.82	4.00e-79	287.00
IUUC-Fal-037506	Ficedula albicollis	46.13	6.00e-80	290.00
IUUC-Fox-037871	Fusarium oxysporum	48.74	1.00e-72	266.00
IUUC-Fso-038350	Fusarium solani	48.74	2.00e-73	268.00
IUUC-Gmo-039647	Gadus morhua	45.23	3.00e-71	261.00
IUUC-Ggr-039859	Gaeumannomyces graminis	47.48	1.00e-71	262.00
IUUC-Gga-040843	Gallus gallus	44.58	6.00e-73	266.00
IUUC-Gac-042601	Gasterosteus aculeatus	45.34	6.00e-70	257.00
IUUC-Gma-042744	Glycine max	74.51	1.00e-154	538.00
IUUC-Ggo-044788	Gorilla gorilla	45.82	2.00e-79	288.00
IUUC-Hsa-045849	Homo sapiens	45.82	2.00e-79	288.00
IUUC-Hvu-047819	Hordeum vulgare	98.50	1.00e-148	518.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	45.82	1.00e-78	285.00
IUUC-Kpa-049393	Komagataella pastoris	49.40	1.00e-62	231.00
IUUC-Lch-049471	Latimeria chalumnae	44.72	1.00e-70	259.00
IUUC-Lpe-051297	Leersia perrieri	89.44	0.00e+00	684.00
IUUC-Loc-052910	Lepisosteus oculatus	45.40	3.00e-70	258.00
IUUC-Lma-053181	Leptosphaeria maculans	46.30	1.00e-72	266.00
IUUC-Laf-054314	Loxodonta africana	43.86	5.00e-77	280.00
IUUC-Mcc-054870	Macaca mulatta	45.82	2.00e-79	288.00
IUUC-Meu-056574	Macropus eugenii	39.29	2.00e-42	165.00
IUUC-Mor-056919	Magnaporthe oryzae	44.44	7.00e-72	263.00
IUUC-Mpo-057614	Magnaporthe poae	46.86	9.00e-66	243.00
IUUC-Mtr-058110	Medicago truncatula	75.63	5.00e-158	550.00
IUUC-Mla-058949	Melampsora laricipopulina	42.72	3.00e-63	234.00
IUUC-Mga-059455	Meleagris gallopavo	46.13	5.00e-79	287.00
IUUC-Mvi-060270	Microbotryum violaceum	42.70	2.00e-70	258.00
IUUC-Mmr-061155	Microcebus murinus	46.44	5.00e-80	290.00
IUUC-Mdo-062037	Monodelphis domestica	45.20	1.00e-77	282.00
IUUC-Mmu-063670	Mus musculus	45.82	3.00e-79	288.00
IUUC-Mac-064711	Musa acuminata	78.93	1.00e-155	541.00
IUUC-Mpu-066734	Mustela putorius furo	45.85	2.00e-79	288.00
IUUC-Mlu-067068	Myotis lucifugus	46.13	2.00e-79	288.00
IUUC-Nfi-068349	Neosartorya fischeri	47.80	7.00e-75	273.00
IUUC-Ncr-068626	Neurospora crassa	48.09	2.00e-68	252.00
IUUC-Nle-069366	Nomascus leucogenys	47.10	4.00e-72	264.00
IUUC-Opr-070993	Ochotona princeps	44.44	6.00e-29	120.00
IUUC-Ont-072196	Oreochromis niloticus	44.62	9.00e-69	253.00
IUUC-Oan-073511	Ornithorhynchus anatinus	45.03	2.00e-77	282.00
IUUC-Ocu-073773	Oryctolagus cuniculus	46.13	2.00e-79	288.00
IUUC-Oba-075726	Oryza barthii	79.26	5.00e-176	609.00
IUUC-Obr-076286	Oryza brachyantha	88.27	0.00e+00	673.00
IUUC-Ogu-078473	Oryza glumaepatula	79.26	3.00e-176	610.00
IUUC-Oin-079393	Oryza indica	88.55	0.00e+00	677.00
IUUC-Olo-080446	Oryza longistaminata	83.52	6.00e-180	622.00
IUUC-Ome-081737	Oryza meridionalis	83.71	1.00e-179	621.00
IUUC-Oni-082853	Oryza nivara	79.26	5.00e-176	609.00
IUUC-Opu-083590	Oryza punctata	87.71	0.00e+00	671.00
IUUC-Oru-084184	Oryza rufipogon	79.26	5.00e-176	609.00
IUUC-Osa-085402	Oryza sativa	88.55	0.00e+00	677.00
IUUC-Ola-086615	Oryzias latipes	46.44	4.00e-70	257.00
IUUC-Olu-087738	Ostreococcus lucimarinus	55.14	2.00e-101	361.00
IUUC-Oga-088101	Otolemur garnettii	45.82	3.00e-79	288.00
IUUC-Oar-090293	Ovis aries	45.12	3.00e-77	281.00
IUUC-Ptr-090503	Pan troglodytes	45.82	2.00e-79	288.00
IUUC-Pan-092477	Papio anubis	44.83	9.00e-75	273.00
IUUC-Psi-093442	Pelodiscus sinensis	46.75	2.00e-81	295.00
IUUC-Pma-094247	Petromyzon marinus	45.73	6.00e-69	253.00
IUUC-Pno-094780	Phaeosphaeria nodorum	45.99	2.00e-80	291.00
IUUC-Ppa-095961	Physcomitrella patens	60.67	1.00e-125	442.00
IUUC-Pfo-096846	Poecilia formosa	46.37	1.00e-71	262.00
IUUC-Pab-098060	Pongo abelii	45.51	4.00e-71	261.00
IUUC-Pop-099914	Populus trichocarpa	78.09	6.00e-161	559.00
IUUC-Pca-100500	Procavia capensis	41.92	1.00e-69	256.00
IUUC-Ppe-102008	Prunus persica	77.59	2.00e-161	560.00
IUUC-Pgr-103666	Puccinia graminis	42.59	1.00e-68	252.00
IUUC-Ptt-103901	Puccinia triticina	43.04	9.00e-68	250.00
IUUC-Pte-104198	Pyrenophora teres	45.68	1.00e-71	262.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	45.37	4.00e-70	257.00
IUUC-Rno-105446	Rattus norvegicus	45.82	3.00e-79	287.00
IUUC-Sce-106355	Saccharomyces cerevisiae	34.51	6.00e-39	153.00
IUUC-Sha-106664	Sarcophilus harrisii	44.27	5.00e-76	277.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	37.69	2.00e-62	231.00
IUUC-Spo-108345	Schizosaccharomyces pombe	35.93	5.00e-61	227.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	46.71	1.00e-62	232.00
IUUC-Smo-109098	Selaginella moellendorffii	58.12	4.00e-126	443.00
IUUC-Sit-109724	Setaria italica	92.24	0.00e+00	662.00
IUUC-Sly-110916	Solanum lycopersicum	76.12	3.00e-157	546.00
IUUC-Stu-112236	Solanum tuberosum	76.40	1.00e-157	548.00
IUUC-Sar-113044	Sorex araneus	45.20	1.00e-77	282.00
IUUC-Sbi-114276	Sorghum bicolor	90.86	0.00e+00	660.00
IUUC-Sre-114963	Sporisorium reilianum	44.79	4.00e-71	260.00
IUUC-Ssc-116301	Sus scrofa	45.12	4.00e-77	281.00
IUUC-Tgu-117265	Taeniopygia guttata	46.13	9.00e-80	289.00
IUUC-Tru-117526	Takifugu rubripes	46.79	1.00e-70	259.00
IUUC-Tsy-119483	Tarsius syrichta	45.82	8.00e-79	286.00
IUUC-Tni-120363	Tetraodon nigroviridis	46.15	4.00e-72	264.00
IUUC-Tca-121731	Theobroma cacao	76.97	7.00e-163	565.00
IUUC-Tre-122221	Trichoderma reesei	48.43	4.00e-73	267.00
IUUC-Tvi-122352	Trichoderma virens	47.48	5.00e-72	263.00
IUUC-Tae-123213	Triticum aestivum	100.00	0.00e+00	717.00
IUUC-Tme-127199	Tuber melanosporum	48.73	2.00e-77	281.00
IUUC-Tbe-128076	Tupaia belangeri	45.51	1.00e-78	286.00
IUUC-Uma-129638	Ustilago maydis	45.40	1.00e-69	255.00
IUUC-Vda-129963	Verticillium dahliae	47.80	6.00e-72	263.00
IUUC-Vpa-130637	Vicugna pacos	38.70	1.00e-57	216.00
IUUC-Vvi-131613	Vitis vinifera	78.15	9.00e-164	568.00
IUUC-Xtr-132924	Xenopus tropicalis	44.62	7.00e-68	250.00
IUUC-Xma-134209	Xiphophorus maculatus	46.13	6.00e-72	263.00
IUUC-Yli-134365	Yarrowia lipolytica	47.40	1.00e-71	263.00
IUUC-Zma-135941	Zea mays	80.89	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence