iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116604

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01019632

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001286.1	ENSTGUT00000001336.1	ENSTGUP00000001323.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.90e-51	171.1	8	152

Active Site

Position(s)	Description	Evidence
98	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYegg..........vFkleiefpedYPfkPPkvkfltkifhPnvyenG 79
           Rl++++k+l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g          +Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G
   Q: 8    RLMRDFKRLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGklltfvsftgTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADG 95
           9**********************9.9*****************8633333333337********************************* PP
   S: 80   kvClsilkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Cl+il+  ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 96   SICLDILQ--NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 152
           *******9..**********************************************996 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MSTPARRRLM RDFKRLQEDP PVGVSGAPSE NNIMQWNAVI FGPEGTPFED GKLLTFVSFT 60
GTFKLVIEFS EEYPNKPPTV RFLSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGTTGTT TGTGCGGGCG CAGCGGGCGC GGGCGGGAGG CGGCGCCGCG GCTCCGCCAT 60
GTCCACCCCG GCGCGCCGCC GCCTCATGCG CGACTTCAAG AGGTGAGCGG GGCCCGCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002120	Ailuropoda melanoleuca	93.83	6.00e-86	308.00
IUUC-Apl-004063	Anas platyrhynchos	95.30	1.00e-80	290.00
IUUC-Aca-005001	Anolis carolinensis	93.21	1.00e-85	307.00
IUUC-Bta-012840	Bos taurus	93.83	6.00e-86	308.00
IUUC-Cja-019737	Callithrix jacchus	93.83	6.00e-86	308.00
IUUC-Cfa-020244	Canis familiaris	93.83	6.00e-86	308.00
IUUC-Cpo-022192	Cavia porcellus	93.83	6.00e-86	308.00
IUUC-Csa-023430	Chlorocebus sabaeus	93.83	6.00e-86	308.00
IUUC-Cho-024773	Choloepus hoffmanni	74.69	5.00e-63	232.00
IUUC-Dno-029661	Dasypus novemcinctus	93.83	6.00e-86	308.00
IUUC-Dor-030452	Dipodomys ordii	93.20	3.00e-76	276.00
IUUC-Ete-032595	Echinops telfairi	90.74	4.00e-83	299.00
IUUC-Eca-033377	Equus caballus	93.83	6.00e-86	308.00
IUUC-Fca-036336	Felis catus	93.83	6.00e-86	308.00
IUUC-Gga-040494	Gallus gallus	93.83	6.00e-86	308.00
IUUC-Hsa-046239	Homo sapiens	93.83	6.00e-86	308.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	93.83	6.00e-86	308.00
IUUC-Laf-053380	Loxodonta africana	93.83	6.00e-86	308.00
IUUC-Mcc-054819	Macaca mulatta	93.83	4.00e-86	309.00
IUUC-Mga-059863	Meleagris gallopavo	92.00	5.00e-77	278.00
IUUC-Mmr-060630	Microcebus murinus	93.83	6.00e-86	308.00
IUUC-Mdo-062676	Monodelphis domestica	93.83	6.00e-86	308.00
IUUC-Mmu-063491	Mus musculus	93.83	6.00e-86	308.00
IUUC-Mpu-065803	Mustela putorius furo	93.83	6.00e-86	308.00
IUUC-Mlu-067147	Myotis lucifugus	93.83	6.00e-86	308.00
IUUC-Nle-070105	Nomascus leucogenys	93.83	6.00e-86	308.00
IUUC-Opr-070935	Ochotona princeps	93.83	6.00e-86	308.00
IUUC-Oan-072706	Ornithorhynchus anatinus	88.68	2.00e-78	283.00
IUUC-Ocu-074130	Oryctolagus cuniculus	93.83	6.00e-86	308.00
IUUC-Oga-088836	Otolemur garnettii	93.83	6.00e-86	308.00
IUUC-Oar-090141	Ovis aries	93.83	6.00e-86	308.00
IUUC-Ptr-091453	Pan troglodytes	93.83	6.00e-86	308.00
IUUC-Pan-092511	Papio anubis	93.83	6.00e-86	308.00
IUUC-Psi-093968	Pelodiscus sinensis	93.21	1.00e-85	307.00
IUUC-Pab-098121	Pongo abelii	93.83	6.00e-86	308.00
IUUC-Rno-105772	Rattus norvegicus	93.83	3.00e-86	309.00
IUUC-Sha-107650	Sarcophilus harrisii	92.59	5.00e-84	301.00
IUUC-Sar-113429	Sorex araneus	93.83	6.00e-86	308.00
IUUC-Ssc-115257	Sus scrofa	91.98	8.00e-84	301.00
IUUC-Tsy-119000	Tarsius syrichta	93.83	6.00e-86	308.00
IUUC-Tbe-127921	Tupaia belangeri	91.98	2.00e-81	293.00
IUUC-Ttr-129121	Tursiops truncatus	93.83	6.00e-86	308.00
IUUC-Vpa-130570	Vicugna pacos	87.07	2.00e-69	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence