iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027416

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 40

Genbank Nucleotide ID

CU571254

Gene Name

usp40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000071197.4	ENSDART00000105098.4	ENSDARP00000095869.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.60e-76	257.1	38	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +G+kN+g tCY+NS++Q+L+++pe+re l++  + +l   ++k++ +     +  +lq+lf++l+  +++  s+++l+++++++++e  
   Q: 38   CGIKNQGGTCYLNSLIQTLLFTPEFREELFHLGPDELGCLADKDKPEakvrVIPLELQRLFSHLLLVDEQTASTTDLTDSFGWTNNE-- 124
           7******************************77766654443222223344899*******************************98.. PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           ++ qqD+qE+ ++l+++le++l                           +++++sli++l++g+l +qi+c+ec  +s+r+e+fldl++
   Q: 125  EMGQQDVQELNRILFSALESSL--------------------------VDTSGSSLIHRLYHGTLVNQITCKECSYISERQEDFLDLTV 187
           **********************..........................7899************************************* PP
   S: 175  pvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           +v+g +      l+++L ++f++ee++eg+n y c+ c ++++a k+ kl+klP++L++ L Rf+f+ +++ r k + ++ fpl+++l+
   Q: 188  SVSGVS-----GLEEALwNMFVEEEMFEGNNLYRCSGCGQLVRAAKSAKLRKLPPFLTISLLRFNFDFTKCERYKETGSYVFPLTFNLR 271
           ******.....9*****9*********************************************************************** PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.................................................. 301
           pfc++++  + ++++YeL++v++H+G++ +GHY++y+k+                                                  
   Q: 272  PFCEQSNWPD-SEYSYELFSVIIHKGGCYGGHYHVYIKDidqlghweapeeeknvkmkvktqkqenkteerktesensletedplsvlt 359
           *****88776.59**************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 360  gilaqeeskcvlvdqlgqkllnkigtpwskkykkqygsiskflqshpevfmlisngtrvalkagvpteasppelvnstaadscpentep 448
           ***********************************************************************************999999 PP
   S: 302  ...........ekgkWllfdDskVtevkeeevleetg..staYvlfYkr 337
                      ++ +W+ ++Ds+Vt+++ ++++++ +  ++aY+lfY++
   Q: 449  etatagenedpDQCHWFDLNDSTVTAITVKDIEKQFQgkESAYMLFYRK 497
           999998776655666*******************9889*********98 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MFGDLFEEDG DGFSSAPGSG VKGRECEPPP PRGKIKLCGI KNQGGTCYLN SLIQTLLFTP 60
EFREELFHLG PDELGCLADK DKPEAKVRVI PLELQRLFSH LLLVDEQTAS TTDLTDSFGW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCAAGCAAA CATGGCTGCG TCCTAAAAAC ACAAATGGTT TTCTACTCAG ATTTCAGTTT 60
TCATTATTTG AAATCAAAGA AATTTAATTT TTCGAACGAG AGATTCGCGT TTAAAATATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:402834

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	49.42	0.00e+00	1083.00
IUUC-Apl-004105	Anas platyrhynchos	50.97	0.00e+00	1190.00
IUUC-Aca-004715	Anolis carolinensis	49.26	0.00e+00	1121.00
IUUC-Ame-011073	Astyanax mexicanus	63.03	0.00e+00	1446.00
IUUC-Bta-012487	Bos taurus	49.34	0.00e+00	1132.00
IUUC-Cja-018937	Callithrix jacchus	48.91	0.00e+00	1137.00
IUUC-Cfa-020645	Canis familiaris	40.86	4.00e-164	572.00
IUUC-Cpo-022160	Cavia porcellus	49.15	0.00e+00	1132.00
IUUC-Csa-023078	Chlorocebus sabaeus	48.91	0.00e+00	1150.00
IUUC-Cho-025013	Choloepus hoffmanni	75.40	7.00e-107	382.00
IUUC-Csv-026193	Ciona savignyi	56.71	9.00e-62	229.00
IUUC-Dno-029639	Dasypus novemcinctus	45.81	0.00e+00	896.00
IUUC-Dor-030624	Dipodomys ordii	65.61	9.00e-113	402.00
IUUC-Ete-032626	Echinops telfairi	38.67	4.00e-114	406.00
IUUC-Eca-034208	Equus caballus	49.45	0.00e+00	1145.00
IUUC-Fca-036006	Felis catus	64.29	1.00e-143	502.00
IUUC-Fal-036925	Ficedula albicollis	50.82	0.00e+00	1129.00
IUUC-Gmo-038597	Gadus morhua	61.11	0.00e+00	1314.00
IUUC-Gga-041171	Gallus gallus	50.08	0.00e+00	1169.00
IUUC-Gac-041362	Gasterosteus aculeatus	61.48	0.00e+00	1345.00
IUUC-Ggo-045069	Gorilla gorilla	47.64	0.00e+00	1016.00
IUUC-Hsa-046715	Homo sapiens	48.57	0.00e+00	1129.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	47.47	0.00e+00	1081.00
IUUC-Lch-050182	Latimeria chalumnae	48.69	0.00e+00	1047.00
IUUC-Loc-052705	Lepisosteus oculatus	61.32	0.00e+00	1502.00
IUUC-Laf-054132	Loxodonta africana	48.99	0.00e+00	1152.00
IUUC-Mcc-055734	Macaca mulatta	49.38	0.00e+00	1149.00
IUUC-Meu-056135	Macropus eugenii	77.06	4.00e-100	360.00
IUUC-Mga-060092	Meleagris gallopavo	50.39	0.00e+00	1154.00
IUUC-Mmr-061546	Microcebus murinus	46.18	0.00e+00	1048.00
IUUC-Mdo-061935	Monodelphis domestica	48.61	0.00e+00	1131.00
IUUC-Mmu-063630	Mus musculus	48.64	0.00e+00	1150.00
IUUC-Mpu-066579	Mustela putorius furo	48.43	0.00e+00	1152.00
IUUC-Mlu-068034	Myotis lucifugus	48.26	0.00e+00	1086.00
IUUC-Nle-069082	Nomascus leucogenys	44.28	0.00e+00	867.00
IUUC-Opr-070953	Ochotona princeps	40.50	4.00e-137	483.00
IUUC-Ont-072435	Oreochromis niloticus	63.47	0.00e+00	1550.00
IUUC-Oan-073339	Ornithorhynchus anatinus	49.77	0.00e+00	1145.00
IUUC-Ocu-073760	Oryctolagus cuniculus	49.77	0.00e+00	1138.00
IUUC-Ola-087015	Oryzias latipes	60.96	0.00e+00	1286.00
IUUC-Oga-088960	Otolemur garnettii	49.53	0.00e+00	1143.00
IUUC-Oar-089853	Ovis aries	49.03	0.00e+00	1140.00
IUUC-Ptr-091093	Pan troglodytes	48.57	0.00e+00	1126.00
IUUC-Pan-091962	Papio anubis	48.40	0.00e+00	1132.00
IUUC-Psi-093691	Pelodiscus sinensis	50.47	0.00e+00	1170.00
IUUC-Pma-094428	Petromyzon marinus	60.35	5.00e-86	311.00
IUUC-Pfo-096983	Poecilia formosa	62.55	0.00e+00	1429.00
IUUC-Pab-097860	Pongo abelii	47.88	0.00e+00	1030.00
IUUC-Pca-100514	Procavia capensis	51.88	3.00e-119	423.00
IUUC-Pva-102771	Pteropus vampyrus	47.58	0.00e+00	1034.00
IUUC-Rno-105405	Rattus norvegicus	48.44	0.00e+00	1143.00
IUUC-Sha-107376	Sarcophilus harrisii	49.63	0.00e+00	1095.00
IUUC-Ssc-115819	Sus scrofa	41.98	0.00e+00	663.00
IUUC-Tgu-117262	Taeniopygia guttata	50.69	0.00e+00	1189.00
IUUC-Tru-117601	Takifugu rubripes	61.25	0.00e+00	1493.00
IUUC-Tsy-118996	Tarsius syrichta	39.03	3.00e-154	539.00
IUUC-Tni-120682	Tetraodon nigroviridis	55.26	0.00e+00	655.00
IUUC-Tbe-127616	Tupaia belangeri	36.02	3.00e-95	343.00
IUUC-Ttr-129075	Tursiops truncatus	46.60	0.00e+00	1038.00
IUUC-Vpa-130108	Vicugna pacos	49.83	0.00e+00	1034.00
IUUC-Xtr-132623	Xenopus tropicalis	47.01	0.00e+00	1080.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence