iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000020027.18	ENSMUST00000139210.7	ENSMUSP00000121305.1
ENSMUSG00000020027.18	ENSMUST00000020215.15	ENSMUSP00000020215.9

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.60e-14	54.0	107	151

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ ++Lqh CRlaI++c+g+     i++LPLP +LkdYL+++++q
   Q: 107  TKPLYTSAPTLQHFCRLAINKCTGT-----IWGLPLPTRLKDYLEEYKFQ 151
           678999*******************.....8***************9886 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

XWYWGSMTVN EAKEKLKEAP EGTFLIRDSS HSDYLLTISV KTSAGPTNLR IEYQDGKFRL 60
DSIICVKSKL KQFDSVVHLI DYYVQMCKDK RTGPEAPRNG TVHLYLTKPL YTSAPTLQHF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGACCGAG GTGCTCAGCT GTTGCAGACA CAGGGGCAGG TACTGGTGGC TTAATAGGCA 60
TTGGCTGGGG ACTTCTCCTT GTTCCCGAGC ACCCCGAGGT GCAGGGTCAG AGGAGGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0035556--P:intracellular signal transduction
GO:0007595--P:lactation
GO:0060749--P:mammary gland alveolus development
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0040015--P:negative regulation of multicellular organism growth
GO:0045666--P:positive regulation of neuron differentiation
GO:0001558--P:regulation of cell growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-007106	Arabidopsis thaliana	35.59	4.00e-02	32.30
IUUC-Bra-017915	Brassica rapa	33.90	7.40e-02	31.60
IUUC-Dor-030447	Dipodomys ordii	97.33	5.00e-86	309.00
IUUC-Ogu-078951	Oryza glumaepatula	26.13	1.70e-01	30.80
IUUC-Oin-079476	Oryza indica	26.13	1.60e-01	30.80
IUUC-Oni-082613	Oryza nivara	26.13	1.60e-01	30.80
IUUC-Oru-085265	Oryza rufipogon	26.13	1.70e-01	30.80
IUUC-Tsy-119335	Tarsius syrichta	92.67	5.00e-83	299.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence