iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132753

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 14

Genbank Nucleotide ID

AAMC01030423

Gene Name

klhl14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000020542.4	ENSXETT00000044377.3	ENSXETP00000044377.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.00e-13	49.4	50	114

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +Dv+l  +g++f++hk+vLa++S++F++lf+++   +   +  ++++ +   +r +l++lYt  ++
   Q: 50   CDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPGPRA-INNLVLQGCSSIGLRLVLEYLYTANVT 114
           9*****************************99999887.9**********************9876 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

LAIFLTRSIA QLHSRGAMSR SGDRTSTFDP SHSDNLLHGL NLLWRKQLFC DVTLTAQGQQ 60
FHCHKAVLAS CSQYFRSLFS SHPGPRAINN LVLQGCSSIG LRLVLEYLYT ANVTLSLDTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGGCCATCT TCCTTACTAG GTCCATAGCC CAGTTGCATT CAAGGGGCGC CATGTCCAGA 60
TCGGGGGACA GGACTTCAAC TTTTGACCCG AGCCATAGTG ACAATTTGCT GCATGGTCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030584--KLHL14
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005783--C:endoplasmic reticulum
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001196	Ailuropoda melanoleuca	84.18	3.00e-159	554.00
IUUC-Bta-012869	Bos taurus	89.82	0.00e+00	1101.00
IUUC-Cja-018731	Callithrix jacchus	91.42	0.00e+00	1106.00
IUUC-Cfa-020355	Canis familiaris	89.07	0.00e+00	1101.00
IUUC-Cpo-021612	Cavia porcellus	89.07	0.00e+00	1100.00
IUUC-Csa-023993	Chlorocebus sabaeus	89.07	0.00e+00	1100.00
IUUC-Dre-027629	Danio rerio	87.52	0.00e+00	1070.00
IUUC-Dno-029185	Dasypus novemcinctus	88.76	0.00e+00	1098.00
IUUC-Fca-036303	Felis catus	88.75	0.00e+00	1094.00
IUUC-Fal-037175	Ficedula albicollis	89.18	0.00e+00	1095.00
IUUC-Gmo-038807	Gadus morhua	86.94	0.00e+00	1040.00
IUUC-Gga-040750	Gallus gallus	90.07	0.00e+00	1098.00
IUUC-Gac-041372	Gasterosteus aculeatus	87.96	0.00e+00	1063.00
IUUC-Ggo-044702	Gorilla gorilla	89.31	0.00e+00	1076.00
IUUC-Hsa-046282	Homo sapiens	89.21	0.00e+00	1101.00
IUUC-Lch-049564	Latimeria chalumnae	91.35	0.00e+00	1100.00
IUUC-Loc-051831	Lepisosteus oculatus	90.26	0.00e+00	1098.00
IUUC-Laf-054353	Loxodonta africana	89.50	0.00e+00	1101.00
IUUC-Mcc-055080	Macaca mulatta	83.52	1.00e-159	555.00
IUUC-Meu-056733	Macropus eugenii	76.17	0.00e+00	751.00
IUUC-Mmr-061263	Microcebus murinus	89.39	0.00e+00	1103.00
IUUC-Mdo-061930	Monodelphis domestica	87.28	0.00e+00	862.00
IUUC-Mmu-064251	Mus musculus	88.92	0.00e+00	1100.00
IUUC-Mpu-066871	Mustela putorius furo	89.23	0.00e+00	1102.00
IUUC-Mlu-067725	Myotis lucifugus	82.33	0.00e+00	775.00
IUUC-Nle-069427	Nomascus leucogenys	88.92	0.00e+00	1100.00
IUUC-Ont-072429	Oreochromis niloticus	89.46	0.00e+00	1078.00
IUUC-Ocu-074635	Oryctolagus cuniculus	89.09	0.00e+00	1102.00
IUUC-Ola-086870	Oryzias latipes	89.13	0.00e+00	1075.00
IUUC-Oga-088397	Otolemur garnettii	89.09	0.00e+00	1102.00
IUUC-Oar-089280	Ovis aries	95.01	0.00e+00	1095.00
IUUC-Ptr-091356	Pan troglodytes	84.38	0.00e+00	1018.00
IUUC-Pan-092718	Papio anubis	89.07	0.00e+00	1100.00
IUUC-Psi-093970	Pelodiscus sinensis	89.09	0.00e+00	1036.00
IUUC-Pfo-096550	Poecilia formosa	89.32	0.00e+00	1073.00
IUUC-Pab-097802	Pongo abelii	88.42	0.00e+00	1090.00
IUUC-Pca-101125	Procavia capensis	84.08	0.00e+00	1019.00
IUUC-Pva-102888	Pteropus vampyrus	89.18	0.00e+00	1026.00
IUUC-Rno-105007	Rattus norvegicus	88.92	0.00e+00	1100.00
IUUC-Sar-113671	Sorex araneus	86.98	0.00e+00	1063.00
IUUC-Ssc-116060	Sus scrofa	89.09	0.00e+00	1102.00
IUUC-Tgu-116795	Taeniopygia guttata	80.78	0.00e+00	965.00
IUUC-Tru-118216	Takifugu rubripes	89.30	0.00e+00	1077.00
IUUC-Tsy-118816	Tarsius syrichta	94.06	4.00e-174	604.00
IUUC-Tni-120281	Tetraodon nigroviridis	92.49	0.00e+00	1039.00
IUUC-Tbe-128057	Tupaia belangeri	84.59	0.00e+00	1024.00
IUUC-Ttr-128618	Tursiops truncatus	78.86	0.00e+00	965.00
IUUC-Vpa-130468	Vicugna pacos	85.47	0.00e+00	670.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence