iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021888

Ensembl Protein ID

ENSCPOP00000004479.2

UniProt Accession

H0V4E1; H0V4E1_CAVPO

Genbank Protein ID

ENSCPOP00000004479

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02051849

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004975.3	ENSCPOT00000005029.2	ENSCPOP00000004479.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-17	61.4	72	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 72   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 101
           8***********777*************** PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

LLAWRLLLRR EGGGRSIAKA AMRAVLTWRD KVEQCIYDLA FKPDGTQLIV AAGNRLLVYE 60
TSDGTLIQPL KGHKDTVYCV AYAKDGKRFA SGSADKSVII WTSKLEGILK YSHNDSIQCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTAGCGT GGCGTCTGTT GCTGAGGCGG GAAGGAGGAG GCCGAAGCAT AGCAAAAGCG 60
GCTATGAGGG CTGTGCTGAC GTGGAGAGAT AAAGTGGAGC AGTGGTGAGG AAAGGGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	85.82	0.00e+00	2176.00
IUUC-Apl-003504	Anas platyrhynchos	86.25	0.00e+00	2149.00
IUUC-Aca-004767	Anolis carolinensis	80.60	0.00e+00	2087.00
IUUC-Ame-011642	Astyanax mexicanus	64.55	0.00e+00	1616.00
IUUC-Bta-012969	Bos taurus	89.34	0.00e+00	1833.00
IUUC-Cel-018670	Caenorhabditis elegans	38.56	0.00e+00	906.00
IUUC-Cja-019249	Callithrix jacchus	83.30	0.00e+00	1686.00
IUUC-Cfa-020915	Canis familiaris	90.52	0.00e+00	1853.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	50.34	0.00e+00	1175.00
IUUC-Csa-023533	Chlorocebus sabaeus	87.80	0.00e+00	1784.00
IUUC-Cin-025121	Ciona intestinalis	60.30	0.00e+00	1553.00
IUUC-Csv-026240	Ciona savignyi	58.48	0.00e+00	1454.00
IUUC-Dno-029685	Dasypus novemcinctus	90.68	0.00e+00	2209.00
IUUC-Dme-032005	Drosophila melanogaster	24.89	8.00e-08	53.10
IUUC-Ete-032682	Echinops telfairi	81.25	0.00e+00	1638.00
IUUC-Eca-033831	Equus caballus	86.20	0.00e+00	2204.00
IUUC-Eeu-034919	Erinaceus europaeus	84.52	0.00e+00	984.00
IUUC-Fca-036559	Felis catus	76.24	0.00e+00	1882.00
IUUC-Fal-037340	Ficedula albicollis	85.08	0.00e+00	2102.00
IUUC-Gga-040595	Gallus gallus	86.11	0.00e+00	2161.00
IUUC-Ggo-045356	Gorilla gorilla	88.00	0.00e+00	1787.00
IUUC-Hsa-046135	Homo sapiens	88.10	0.00e+00	1787.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	80.41	0.00e+00	1745.00
IUUC-Lch-050183	Latimeria chalumnae	80.43	0.00e+00	1172.00
IUUC-Loc-052049	Lepisosteus oculatus	83.40	0.00e+00	2097.00
IUUC-Laf-053728	Loxodonta africana	77.92	0.00e+00	1930.00
IUUC-Mcc-054971	Macaca mulatta	88.10	0.00e+00	1785.00
IUUC-Meu-056446	Macropus eugenii	78.16	0.00e+00	2028.00
IUUC-Mga-059296	Meleagris gallopavo	71.23	0.00e+00	1758.00
IUUC-Mmr-061232	Microcebus murinus	88.71	0.00e+00	1801.00
IUUC-Mdo-062115	Monodelphis domestica	85.44	0.00e+00	2184.00
IUUC-Mmu-063664	Mus musculus	85.31	0.00e+00	2184.00
IUUC-Mpu-066136	Mustela putorius furo	86.12	0.00e+00	1783.00
IUUC-Mlu-068238	Myotis lucifugus	88.15	0.00e+00	1857.00
IUUC-Nle-069003	Nomascus leucogenys	84.62	0.00e+00	1676.00
IUUC-Ont-072080	Oreochromis niloticus	66.19	0.00e+00	1670.00
IUUC-Oan-072891	Ornithorhynchus anatinus	90.49	0.00e+00	954.00
IUUC-Ocu-074262	Oryctolagus cuniculus	82.57	0.00e+00	2046.00
IUUC-Ola-086538	Oryzias latipes	68.83	0.00e+00	1741.00
IUUC-Oga-088722	Otolemur garnettii	90.30	0.00e+00	1807.00
IUUC-Oar-089249	Ovis aries	89.83	0.00e+00	2187.00
IUUC-Ptr-090752	Pan troglodytes	88.00	0.00e+00	1783.00
IUUC-Pan-092472	Papio anubis	88.12	0.00e+00	1792.00
IUUC-Psi-093335	Pelodiscus sinensis	87.21	0.00e+00	2176.00
IUUC-Pma-094520	Petromyzon marinus	71.01	0.00e+00	1663.00
IUUC-Ppa-095600	Physcomitrella patens	61.06	8.00e-40	155.00
IUUC-Pfo-096526	Poecilia formosa	64.03	0.00e+00	1568.00
IUUC-Pab-098428	Pongo abelii	86.36	0.00e+00	1078.00
IUUC-Pca-100233	Procavia capensis	81.29	0.00e+00	731.00
IUUC-Pva-103064	Pteropus vampyrus	73.13	0.00e+00	1823.00
IUUC-Rno-105764	Rattus norvegicus	85.39	0.00e+00	2171.00
IUUC-Sha-106649	Sarcophilus harrisii	85.03	0.00e+00	2167.00
IUUC-Smo-109478	Selaginella moellendorffii	41.05	0.00e+00	915.00
IUUC-Tgu-116870	Taeniopygia guttata	80.92	0.00e+00	2014.00
IUUC-Tru-118661	Takifugu rubripes	70.02	0.00e+00	1813.00
IUUC-Tsy-119640	Tarsius syrichta	73.90	0.00e+00	639.00
IUUC-Tni-120812	Tetraodon nigroviridis	64.31	0.00e+00	1565.00
IUUC-Ttr-128862	Tursiops truncatus	89.31	0.00e+00	1867.00
IUUC-Vpa-130049	Vicugna pacos	74.78	3.00e-144	506.00
IUUC-Xtr-131914	Xenopus tropicalis	80.93	0.00e+00	2017.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence