iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000004804.3	ENSCJAT00000009282.1	ENSCJAP00000008782.1
ENSCJAG00000004804.3	ENSCJAT00000009300.3	ENSCJAP00000008798.3
ENSCJAG00000004804.3	ENSCJAT00000062358.1	ENSCJAP00000044622.1
ENSCJAG00000004804.3	ENSCJAT00000053916.1	ENSCJAP00000042640.1
ENSCJAG00000004804.3	ENSCJAT00000009319.1	ENSCJAP00000008816.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-07	32.7	376	415

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 376  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 415
           99********.******************....555555.5****8 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MANSMNGRNP GGRGGNPRKG RILGIIDAIQ DAVGPPKQAA ADRRTVEKTW KLMDKVVRLC 60
QNPKLQLKNS PPYILDILPD TYQHLRLILS KYDDNQKLAQ LSENEYFKIY IDSLMKKSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAGCCCCA GACGGCTTTG GCTCCCGCTC CCGACGCTCA CGCCCACCTG CCACCCCCTT 60
ATTGGTTAGC TCCCTCGTGC CTTGCATCCC TTGTTCCATT TTCTTTCCCG TTTCCACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	88.24	0.00e+00	1499.00
IUUC-Apl-004148	Anas platyrhynchos	78.78	0.00e+00	1333.00
IUUC-Aca-005204	Anolis carolinensis	75.00	0.00e+00	1278.00
IUUC-Ame-011919	Astyanax mexicanus	78.17	0.00e+00	835.00
IUUC-Bta-013044	Bos taurus	88.54	0.00e+00	1510.00
IUUC-Cfa-021054	Canis familiaris	88.24	0.00e+00	1540.00
IUUC-Cpo-022514	Cavia porcellus	85.64	0.00e+00	1514.00
IUUC-Csa-024110	Chlorocebus sabaeus	89.95	0.00e+00	1559.00
IUUC-Cho-024886	Choloepus hoffmanni	71.09	0.00e+00	979.00
IUUC-Dre-027480	Danio rerio	84.80	0.00e+00	874.00
IUUC-Dno-028923	Dasypus novemcinctus	88.54	0.00e+00	1510.00
IUUC-Dor-031040	Dipodomys ordii	89.19	0.00e+00	805.00
IUUC-Ete-032406	Echinops telfairi	83.66	0.00e+00	1378.00
IUUC-Eca-033849	Equus caballus	87.63	0.00e+00	1524.00
IUUC-Fca-036224	Felis catus	87.54	0.00e+00	1512.00
IUUC-Fal-036860	Ficedula albicollis	96.13	0.00e+00	999.00
IUUC-Gga-040159	Gallus gallus	95.07	0.00e+00	1036.00
IUUC-Gac-042312	Gasterosteus aculeatus	83.30	0.00e+00	870.00
IUUC-Ggo-045175	Gorilla gorilla	87.74	0.00e+00	1509.00
IUUC-Hsa-046306	Homo sapiens	89.85	0.00e+00	1557.00
IUUC-Lch-049931	Latimeria chalumnae	59.79	0.00e+00	821.00
IUUC-Loc-052524	Lepisosteus oculatus	88.25	0.00e+00	900.00
IUUC-Laf-053635	Loxodonta africana	84.19	0.00e+00	1439.00
IUUC-Mcc-055536	Macaca mulatta	89.95	0.00e+00	1557.00
IUUC-Meu-056045	Macropus eugenii	71.71	0.00e+00	1140.00
IUUC-Mga-060177	Meleagris gallopavo	82.63	0.00e+00	991.00
IUUC-Mmr-061088	Microcebus murinus	89.25	0.00e+00	1542.00
IUUC-Mdo-062020	Monodelphis domestica	82.38	0.00e+00	1423.00
IUUC-Mmu-063114	Mus musculus	83.16	0.00e+00	1436.00
IUUC-Mpu-066632	Mustela putorius furo	88.95	0.00e+00	1548.00
IUUC-Mlu-067145	Myotis lucifugus	88.54	0.00e+00	1537.00
IUUC-Ont-072323	Oreochromis niloticus	84.04	0.00e+00	872.00
IUUC-Oan-073165	Ornithorhynchus anatinus	82.93	0.00e+00	1460.00
IUUC-Ocu-074723	Oryctolagus cuniculus	88.54	0.00e+00	1532.00
IUUC-Oga-088021	Otolemur garnettii	87.84	0.00e+00	1513.00
IUUC-Oar-089809	Ovis aries	88.34	0.00e+00	1510.00
IUUC-Ptr-090834	Pan troglodytes	89.85	0.00e+00	1557.00
IUUC-Pan-092225	Papio anubis	89.85	0.00e+00	1559.00
IUUC-Psi-093317	Pelodiscus sinensis	79.64	0.00e+00	1385.00
IUUC-Pma-094249	Petromyzon marinus	77.12	1.00e-125	442.00
IUUC-Pab-097595	Pongo abelii	89.85	0.00e+00	1556.00
IUUC-Pca-100844	Procavia capensis	71.70	0.00e+00	1156.00
IUUC-Pva-103216	Pteropus vampyrus	99.06	0.00e+00	1052.00
IUUC-Rno-105381	Rattus norvegicus	87.42	0.00e+00	1521.00
IUUC-Sha-107574	Sarcophilus harrisii	82.23	0.00e+00	1417.00
IUUC-Sar-113500	Sorex araneus	76.55	0.00e+00	1216.00
IUUC-Ssc-115856	Sus scrofa	86.67	0.00e+00	1293.00
IUUC-Tgu-116866	Taeniopygia guttata	95.26	0.00e+00	1006.00
IUUC-Tru-118579	Takifugu rubripes	85.83	0.00e+00	877.00
IUUC-Tsy-119167	Tarsius syrichta	76.79	0.00e+00	1264.00
IUUC-Tni-120788	Tetraodon nigroviridis	84.57	0.00e+00	885.00
IUUC-Tbe-127830	Tupaia belangeri	82.00	0.00e+00	1013.00
IUUC-Ttr-128631	Tursiops truncatus	89.25	0.00e+00	1551.00
IUUC-Vpa-130713	Vicugna pacos	86.54	0.00e+00	1308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence