iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090729

UUCD1 version

UUC-PaT-00433

Ensembl Protein ID

ENSPTRP00000021390.5

UniProt Accession

H2QIS3; H2QIS3_PANTR

Genbank Protein ID

JAA07635.1; JAA20888.1; JAA24152.1; JAA41148.1

Protein Name

Speckle-type POZ protein-like

Genbank Nucleotide ID

AACZ03018554; GABF01001257; GABD01008948; GABE01003591

Gene Name

SPOPL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000012504.5	ENSPTRT00000023198.5	ENSPTRP00000021390.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.90e-29	99.5	200	266
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.30e-07	30.9	299	326

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D+ + v g+ef+ahk+vLaa+S+vF+a+f++e+eesk k++vei+d++pevf+++++F+Ytg++++ 
   Q: 200  TDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESK-KNRVEINDLDPEVFKEMMRFIYTGRAPNL 266
           7*************************************.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfil 28
           +eN+++ l +Adl+++++Lk +a+dfi+
   Q: 299  VENVADTLVLADLHSAEQLKAQAIDFIN 326
           79*************************7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSREPTPPLP GDMSTGPIAE SWCYTQVKVV KFSYMWTINN FSFCREEMGE VLKSSTFSSG 60
PSDKMKWCLR VNPKGLDDES KDYLSLYLLL VSCPKSEVRA KFKFSLLNAK REETKAMESQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGCTGGA GCCGGGGCTG GAGTCGTAAC TCGGAAGCCG GAGCCCAGAC GGGCCCGCGG 60
CGGGGGGGTG GGGGCTGCGC GGGGGCGGGA GTGGCGGAGG TGGCCGCCCC TGGCGGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB
PF00917--MATH

SMART

SM00225--BTB
SM00061--MATH

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0031397--P:negative regulation of protein ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

KEGG

ptr:460095

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000119	Aegilops tauschii	33.23	3.00e-42	165.00
IUUC-Aml-001309	Ailuropoda melanoleuca	98.47	0.00e+00	766.00
IUUC-Atr-002922	Amborella trichopoda	29.84	5.00e-42	164.00
IUUC-Apl-003864	Anas platyrhynchos	95.41	0.00e+00	764.00
IUUC-Aca-005320	Anolis carolinensis	92.86	0.00e+00	737.00
IUUC-Ath-007670	Arabidopsis thaliana	28.35	3.00e-38	152.00
IUUC-Ate-010494	Aspergillus terreus	36.36	2.00e-07	49.70
IUUC-Ame-011843	Astyanax mexicanus	90.31	0.00e+00	731.00
IUUC-Bta-013528	Bos taurus	93.11	0.00e+00	709.00
IUUC-Bol-015218	Brassica oleracea	30.51	5.00e-43	168.00
IUUC-Bra-016833	Brassica rapa	30.91	3.00e-43	169.00
IUUC-Cja-019227	Callithrix jacchus	96.43	0.00e+00	766.00
IUUC-Cfa-020990	Canis familiaris	98.72	0.00e+00	768.00
IUUC-Cpo-021660	Cavia porcellus	99.49	0.00e+00	815.00
IUUC-Csa-023569	Chlorocebus sabaeus	96.88	3.00e-162	563.00
IUUC-Cho-024732	Choloepus hoffmanni	87.76	0.00e+00	685.00
IUUC-Dre-027880	Danio rerio	91.07	0.00e+00	734.00
IUUC-Dno-029399	Dasypus novemcinctus	97.70	0.00e+00	778.00
IUUC-Dor-030177	Dipodomys ordii	86.70	0.00e+00	646.00
IUUC-Ete-032759	Echinops telfairi	90.82	0.00e+00	719.00
IUUC-Eca-033858	Equus caballus	98.98	0.00e+00	770.00
IUUC-Eeu-035156	Erinaceus europaeus	99.08	0.00e+00	670.00
IUUC-Fca-036500	Felis catus	98.72	0.00e+00	768.00
IUUC-Fal-037023	Ficedula albicollis	95.41	0.00e+00	764.00
IUUC-Fox-037845	Fusarium oxysporum	36.14	2.00e-10	58.90
IUUC-Gmo-038605	Gadus morhua	91.58	0.00e+00	737.00
IUUC-Gga-040204	Gallus gallus	95.41	0.00e+00	764.00
IUUC-Gac-042260	Gasterosteus aculeatus	91.84	0.00e+00	740.00
IUUC-Gma-043055	Glycine max	30.38	4.00e-43	168.00
IUUC-Ggo-045160	Gorilla gorilla	99.74	0.00e+00	816.00
IUUC-Hsa-045729	Homo sapiens	100.00	0.00e+00	817.00
IUUC-Hvu-047528	Hordeum vulgare	30.96	4.00e-40	158.00
IUUC-Itr-048153	Ictidomys tridecemlineatus	99.23	0.00e+00	815.00
IUUC-Lch-050036	Latimeria chalumnae	91.33	0.00e+00	706.00
IUUC-Lpe-050805	Leersia perrieri	31.34	1.00e-45	176.00
IUUC-Loc-052332	Lepisosteus oculatus	89.97	0.00e+00	722.00
IUUC-Lma-053180	Leptosphaeria maculans	20.86	7.00e-07	48.90
IUUC-Laf-053691	Loxodonta africana	97.45	0.00e+00	780.00
IUUC-Mcc-055808	Macaca mulatta	99.74	0.00e+00	816.00
IUUC-Mtr-058012	Medicago truncatula	30.35	4.00e-43	168.00
IUUC-Mga-059990	Meleagris gallopavo	95.41	0.00e+00	764.00
IUUC-Mmr-061748	Microcebus murinus	98.72	0.00e+00	810.00
IUUC-Mdo-062472	Monodelphis domestica	90.48	0.00e+00	681.00
IUUC-Mmu-063522	Mus musculus	96.43	0.00e+00	771.00
IUUC-Mac-064772	Musa acuminata	31.34	2.00e-42	166.00
IUUC-Mpu-065894	Mustela putorius furo	92.57	0.00e+00	751.00
IUUC-Mlu-067879	Myotis lucifugus	97.96	0.00e+00	763.00
IUUC-Nle-069115	Nomascus leucogenys	100.00	0.00e+00	817.00
IUUC-Ont-072569	Oreochromis niloticus	91.58	0.00e+00	737.00
IUUC-Oan-073449	Ornithorhynchus anatinus	92.86	0.00e+00	741.00
IUUC-Ocu-073817	Oryctolagus cuniculus	98.98	0.00e+00	813.00
IUUC-Oba-075042	Oryza barthii	33.04	4.00e-44	172.00
IUUC-Obr-076906	Oryza brachyantha	33.43	1.00e-38	153.00
IUUC-Ogl-077426	Oryza glaberrima	33.04	2.00e-44	172.00
IUUC-Ogu-078825	Oryza glumaepatula	31.62	4.00e-40	160.00
IUUC-Oin-079531	Oryza indica	33.63	3.00e-42	165.00
IUUC-Olo-080313	Oryza longistaminata	37.59	4.00e-39	155.00
IUUC-Ome-081371	Oryza meridionalis	32.83	3.00e-39	155.00
IUUC-Oni-082862	Oryza nivara	33.24	2.00e-42	167.00
IUUC-Opu-083831	Oryza punctata	31.81	8.00e-39	154.00
IUUC-Oru-084513	Oryza rufipogon	32.15	4.00e-34	139.00
IUUC-Osa-085702	Oryza sativa	33.04	9.00e-41	160.00
IUUC-Ola-086485	Oryzias latipes	90.08	0.00e+00	724.00
IUUC-Oga-087982	Otolemur garnettii	92.86	0.00e+00	728.00
IUUC-Oar-089667	Ovis aries	97.96	0.00e+00	761.00
IUUC-Pan-091988	Papio anubis	99.49	0.00e+00	815.00
IUUC-Psi-093103	Pelodiscus sinensis	95.66	0.00e+00	766.00
IUUC-Pno-094888	Phaeosphaeria nodorum	23.68	4.00e-05	42.70
IUUC-Pfo-096279	Poecilia formosa	83.21	0.00e+00	649.00
IUUC-Pab-098431	Pongo abelii	100.00	0.00e+00	817.00
IUUC-Pop-099010	Populus trichocarpa	30.11	1.00e-33	137.00
IUUC-Pca-100373	Procavia capensis	77.23	9.00e-136	476.00
IUUC-Ppe-101816	Prunus persica	30.08	6.00e-36	145.00
IUUC-Pva-102660	Pteropus vampyrus	98.72	0.00e+00	768.00
IUUC-Rno-105020	Rattus norvegicus	88.92	0.00e+00	727.00
IUUC-Sha-107038	Sarcophilus harrisii	95.41	0.00e+00	762.00
IUUC-Sit-110155	Setaria italica	35.11	1.00e-38	153.00
IUUC-Ssc-116199	Sus scrofa	93.88	0.00e+00	716.00
IUUC-Tgu-116755	Taeniopygia guttata	94.90	0.00e+00	754.00
IUUC-Tru-118288	Takifugu rubripes	89.03	0.00e+00	716.00
IUUC-Tni-119955	Tetraodon nigroviridis	88.83	0.00e+00	719.00
IUUC-Tre-122160	Trichoderma reesei	34.25	1.00e-10	60.10
IUUC-Tvi-122498	Trichoderma virens	31.19	1.00e-11	63.20
IUUC-Tae-123958	Triticum aestivum	33.23	3.00e-42	165.00
IUUC-Tur-126285	Triticum urartu	37.26	3.00e-42	165.00
IUUC-Ttr-129261	Tursiops truncatus	98.21	0.00e+00	764.00
IUUC-Vpa-130728	Vicugna pacos	98.53	0.00e+00	655.00
IUUC-Xtr-132576	Xenopus tropicalis	87.98	2.00e-178	618.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence