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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063533
UUCD1 version UUC-MuM-00656
Ensembl Protein ID ENSMUSP00000065643.6
UniProt Accession Q8BQM8; Q8BRL0; Q8R2W0; EMAL5_MOUSE
Genbank Protein ID BAC31743.1; BAC33148.1; AAH27154.1
Protein Name Echinoderm microtubule-associated protein-like 5
Genbank Nucleotide ID AC159193; AK047762; BC027154
Gene Name Eml5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000051166.9 ENSMUST00000065716.6 ENSMUSP00000065643.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 5.20e-58 191.5 1700 1732
UBD/Beta-Prp 1.40e-124 416.2 726 940
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htd.svtclaf.sd.tllvsGsdDgtikvWDlr 31
           H d ++++la  ++ ++++s++ Dgt+++WD+ 
   Q: 1700 HVDgPIWGLAThPSrDFFLSAAEDGTVRLWDIA 1732
           5553699999898889***************75 PP
   

   UBD/Beta-Prp
   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd +i vwd++t k l+ l   h+ ++ av+fs dgk l++++ D  +ti +wd ++g+ +++ +g
   Q: 726  HDDDILCLAIHPLKDYVATGqvGRDPSIHVWDTETIKPLSILkGYHQYGICAVDFSADGKRLASVGIDdsHTIVLWDWKKGEKLSVTRG 814
           4555566************95569******************5559******************99999******************** PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
            +d++  ++++p+  dkl++++  +  + w    g  + +       g++++ +c+v+  ++ + +sG+  + v +W  +  +l++t +
   Q: 815  SKDKIFVVKMNPYVpDKLITAG-IKHMKFWRRAGGGLIGKkgyvGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDVFLVKTVK 900
           ************9978888887.9999***99888888889998455677799************************..889******9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
             h+++v s+   +  k +v+g++dg v lwd + ++c++t+ 
   Q: 901  A-HDGPVFSMHALE--KGFVTGGKDGMVALWDDSFERCLKTYA 940
           8.********9888..67**********************996 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
 May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
Protein Sequence
(Fasta)
MAARSAPSCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFFRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTVSV LKDVHTHGIA CLAFDLDGQR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063533|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACTCAGCTGG GCTCGGGAGC GCGCGGCGCG GCTCCGCCGG GGCTGTGGAG GCGAGGTAGC 60
GGCTAGACCG GAGCGCCGCA GGTGACCCGG GCGGGGAGTC CGGTGCGCGG GGCGGGCGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063533|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005874--C:microtubule
GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding
KEGG mmu:319670
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002225 Ailuropoda melanoleuca 95.34 0.00e+00 3788.00
IUUC-Apl-003360 Anas platyrhynchos 90.03 0.00e+00 3511.00
IUUC-Ame-011681 Astyanax mexicanus 84.82 0.00e+00 3484.00
IUUC-Bta-012838 Bos taurus 95.25 0.00e+00 3831.00
IUUC-Cja-019068 Callithrix jacchus 95.75 0.00e+00 3829.00
IUUC-Cfa-020531 Canis familiaris 95.30 0.00e+00 3855.00
IUUC-Cpo-022304 Cavia porcellus 92.69 0.00e+00 3618.00
IUUC-Csa-023621 Chlorocebus sabaeus 94.88 0.00e+00 3477.00
IUUC-Cho-024944 Choloepus hoffmanni 75.49 0.00e+00 1459.00
IUUC-Dre-028772 Danio rerio 84.67 0.00e+00 3484.00
IUUC-Dno-030063 Dasypus novemcinctus 94.20 0.00e+00 3769.00
IUUC-Dor-030980 Dipodomys ordii 86.44 0.00e+00 1577.00
IUUC-Ete-032554 Echinops telfairi 92.84 0.00e+00 1047.00
IUUC-Eca-033909 Equus caballus 95.59 0.00e+00 3534.00
IUUC-Eeu-035180 Erinaceus europaeus 77.84 0.00e+00 1430.00
IUUC-Fal-037219 Ficedula albicollis 90.42 0.00e+00 3633.00
IUUC-Gmo-039146 Gadus morhua 80.33 0.00e+00 3283.00
IUUC-Gga-041095 Gallus gallus 89.82 0.00e+00 2616.00
IUUC-Gac-041341 Gasterosteus aculeatus 82.87 0.00e+00 3375.00
IUUC-Hsa-045997 Homo sapiens 95.80 0.00e+00 3829.00
IUUC-Lch-050306 Latimeria chalumnae 84.20 0.00e+00 3171.00
IUUC-Loc-052215 Lepisosteus oculatus 84.62 0.00e+00 3521.00
IUUC-Laf-054044 Loxodonta africana 94.04 0.00e+00 3788.00
IUUC-Mcc-054733 Macaca mulatta 95.90 0.00e+00 3828.00
IUUC-Mga-059666 Meleagris gallopavo 89.00 0.00e+00 3469.00
IUUC-Mmr-060995 Microcebus murinus 96.06 0.00e+00 3823.00
IUUC-Mdo-062482 Monodelphis domestica 92.11 0.00e+00 3732.00
IUUC-Mpu-066704 Mustela putorius furo 95.55 0.00e+00 3843.00
IUUC-Mlu-067592 Myotis lucifugus 95.04 0.00e+00 3796.00
IUUC-Nle-069911 Nomascus leucogenys 95.50 0.00e+00 3815.00
IUUC-Ont-071966 Oreochromis niloticus 84.55 0.00e+00 3484.00
IUUC-Ola-086738 Oryzias latipes 84.11 0.00e+00 3439.00
IUUC-Oga-088436 Otolemur garnettii 93.00 0.00e+00 3726.00
IUUC-Oar-090153 Ovis aries 94.79 0.00e+00 3679.00
IUUC-Ptr-091008 Pan troglodytes 95.50 0.00e+00 3807.00
IUUC-Pan-092404 Papio anubis 95.45 0.00e+00 3801.00
IUUC-Psi-093417 Pelodiscus sinensis 89.50 0.00e+00 3495.00
IUUC-Pfo-096073 Poecilia formosa 84.72 0.00e+00 3489.00
IUUC-Pab-097900 Pongo abelii 95.19 0.00e+00 3808.00
IUUC-Pva-102880 Pteropus vampyrus 91.27 0.00e+00 3477.00
IUUC-Rno-106084 Rattus norvegicus 98.48 0.00e+00 3929.00
IUUC-Sha-106974 Sarcophilus harrisii 92.23 0.00e+00 3726.00
IUUC-Ssc-116057 Sus scrofa 95.31 0.00e+00 3733.00
IUUC-Tru-118444 Takifugu rubripes 83.35 0.00e+00 3407.00
IUUC-Tsy-118941 Tarsius syrichta 83.59 0.00e+00 2793.00
IUUC-Tni-120683 Tetraodon nigroviridis 83.27 0.00e+00 3263.00
IUUC-Tbe-127467 Tupaia belangeri 87.23 0.00e+00 1816.00
IUUC-Ttr-129138 Tursiops truncatus 91.26 0.00e+00 3495.00
IUUC-Vpa-130083 Vicugna pacos 89.22 0.00e+00 3392.00
IUUC-Xtr-131835 Xenopus tropicalis 87.48 0.00e+00 3613.00
Created Date 25-Jun-2017

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