iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003705

Ensembl Protein ID

ENSAPLP00000000292.1

UniProt Accession

U3HZ72; U3HZ72_ANAPL

Genbank Protein ID

ENSAPLP00000000292

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ADON01142923

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000000882.1	ENSAPLT00000000860.1	ENSAPLP00000000292.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.40e-09	35.6	159	205

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 159  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 205
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

HSVEALKEID DVYEKYKSEN DPTQKKRLQQ HLQRALINSQ ELGDEKIQIV TQMLELVENR 60
ARQMETHSQC FQDLSENEKP LEKAKMESCQ PERSSRRPRR QRTSESRDLC HIANGIDDCD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTCTGTAG AAGCGCTAAA AGAAATAGAT GATGTCTATG AAAAATACAA GTCGGAAAAT 60
GATCCCACTC AGAAGAAACG CCTGCAGCAG CATCTTCAGC GTGCGTTAAT CAACAGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	81.78	1.00e-82	299.00
IUUC-Aca-004990	Anolis carolinensis	89.24	2.00e-91	328.00
IUUC-Bta-012721	Bos taurus	80.93	6.00e-82	296.00
IUUC-Cja-018960	Callithrix jacchus	88.95	2.00e-73	268.00
IUUC-Cfa-020869	Canis familiaris	80.93	3.00e-82	297.00
IUUC-Cpo-021414	Cavia porcellus	79.24	4.00e-80	290.00
IUUC-Csa-023304	Chlorocebus sabaeus	90.00	8.00e-75	273.00
IUUC-Dno-029945	Dasypus novemcinctus	81.36	1.00e-83	302.00
IUUC-Dor-030141	Dipodomys ordii	79.66	8.00e-79	286.00
IUUC-Ete-032709	Echinops telfairi	87.00	5.00e-89	320.00
IUUC-Eca-033432	Equus caballus	80.93	1.00e-81	295.00
IUUC-Eeu-035285	Erinaceus europaeus	91.13	1.00e-82	298.00
IUUC-Fca-036467	Felis catus	80.93	8.00e-82	296.00
IUUC-Fal-036700	Ficedula albicollis	97.35	2.00e-103	367.00
IUUC-Gga-040175	Gallus gallus	99.10	9.00e-104	369.00
IUUC-Hsa-045837	Homo sapiens	90.00	8.00e-75	273.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	80.51	9.00e-82	296.00
IUUC-Lch-049965	Latimeria chalumnae	84.30	6.00e-86	310.00
IUUC-Laf-053353	Loxodonta africana	87.50	1.00e-89	321.00
IUUC-Mcc-055155	Macaca mulatta	89.08	5.00e-65	239.00
IUUC-Meu-056470	Macropus eugenii	89.69	3.00e-90	324.00
IUUC-Mga-059570	Meleagris gallopavo	99.10	4.00e-103	366.00
IUUC-Mmr-061385	Microcebus murinus	89.47	3.00e-74	271.00
IUUC-Mdo-062144	Monodelphis domestica	90.13	2.00e-90	325.00
IUUC-Mmu-063215	Mus musculus	80.93	1.00e-81	295.00
IUUC-Mpu-065749	Mustela putorius furo	80.93	2.00e-82	297.00
IUUC-Mlu-067245	Myotis lucifugus	69.46	2.00e-73	267.00
IUUC-Nle-069968	Nomascus leucogenys	90.00	5.00e-74	270.00
IUUC-Ocu-074870	Oryctolagus cuniculus	81.78	8.00e-83	299.00
IUUC-Oga-088336	Otolemur garnettii	90.00	1.00e-74	272.00
IUUC-Oar-090136	Ovis aries	80.08	1.00e-81	295.00
IUUC-Ptr-091348	Pan troglodytes	90.00	2.00e-74	271.00
IUUC-Pan-092819	Papio anubis	90.00	8.00e-75	273.00
IUUC-Psi-093854	Pelodiscus sinensis	93.10	2.00e-68	250.00
IUUC-Pab-098346	Pongo abelii	90.53	2.00e-75	275.00
IUUC-Pca-100278	Procavia capensis	86.55	2.00e-88	318.00
IUUC-Pva-103190	Pteropus vampyrus	80.93	5.00e-82	296.00
IUUC-Rno-104940	Rattus norvegicus	79.24	1.00e-80	291.00
IUUC-Sha-107533	Sarcophilus harrisii	89.69	6.00e-90	323.00
IUUC-Sar-113630	Sorex araneus	89.66	5.00e-81	293.00
IUUC-Ssc-115734	Sus scrofa	80.93	6.00e-82	296.00
IUUC-Tgu-117034	Taeniopygia guttata	99.11	7.00e-104	369.00
IUUC-Tsy-119494	Tarsius syrichta	89.47	9.00e-74	269.00
IUUC-Ttr-128442	Tursiops truncatus	89.66	5.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence