iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048504

Ensembl Protein ID

ENSSTOP00000021905.1

UniProt Accession

I3NC08; I3NC08_ICTTR

Genbank Protein ID

ENSSTOP00000021905

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01044196

Gene Name

ATG16L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000027288.1	ENSSTOT00000026451.1	ENSSTOP00000021905.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-30	104.3	389	428
UBD/Beta-Prp	2.40e-63	214.1	298	588

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           gH+++v + +f  ++ ++vsGs+D t+k+WDlr+ v++k+
   Q: 389  GHSGKVLSAKFllDNARIVSGSHDRTLKLWDLRSKVCIKT 428
           8***********64489********************985 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvht 89
            +++++h++ +++v+fsp+++llatg++d+++k+w+++  k+    slsg +a++t+++f++ g +l+ +s+D + ++w ++++   ht
   Q: 298  LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCefKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHT 386
           57899************************************9989******************************************** PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           l+gh+ +vls +f  ++ ++vsGshdrt+++wdl+++ c++++++g +    c  + +++++++sG+ D+++r+Wd+++++++r+++  
   Q: 387  LTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSS----CNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREME-- 469
           *****************************************9999988....888888889*************************6.. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
             ++++ l+++++++el+s+s+d  +k+ dl+t+ + +t+ +      +  ++v fsp++ +++ gs++gs+++W + +g++ k+l+++
   Q: 470  LLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGfkcgSDWTRVVFSPDGSYVAAGSAEGSLYVWSVLTGKVEKVLSKQ 558
           69**********************************99999988888877777************************************ PP
   S: 264  nssvisvavlsfgdnvlvlgsedskvniwk 293
           +ss+i   ++s+++ ++v++++ sk+ +w+
   Q: 559  HSSSINAVAWSPSGVHVVSVDKSSKAVLWA 588
           *****************************7 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSSGLRAADF PRWKRHIAEE LRRRDRLQRQ SFEEIILQYN KLLEKSDLHS VLAQKLQAEK 60
HDIPNRHEIS PGHDGTWNDS QLQEMAELRI KHQEELTELH KKRGELAQLV IDLNNQMQQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCGGGCTG CGGCCGCCTG CCTCCGCTGG GATCGGCGGC GCTGAAGCGC CGGGGCAGCG 60
TGCGACATGT CTTCGGGCCT CCGCGCTGCC GACTTTCCCC GCTGGAAGCG CCACATTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005930--C:axoneme
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000090	Aegilops tauschii	25.00	2.00e-36	147.00
IUUC-Aml-002242	Ailuropoda melanoleuca	82.87	0.00e+00	982.00
IUUC-Atr-003073	Amborella trichopoda	26.02	9.00e-32	131.00
IUUC-Apl-003384	Anas platyrhynchos	83.22	0.00e+00	994.00
IUUC-Aca-004962	Anolis carolinensis	80.61	0.00e+00	969.00
IUUC-Aly-005435	Arabidopsis lyrata	30.53	2.00e-49	189.00
IUUC-Ath-006948	Arabidopsis thaliana	28.99	2.00e-51	196.00
IUUC-Ame-010915	Astyanax mexicanus	77.47	5.00e-150	523.00
IUUC-Bta-012388	Bos taurus	86.86	0.00e+00	1083.00
IUUC-Bdi-014231	Brachypodium distachyon	25.49	1.00e-39	157.00
IUUC-Bol-016174	Brassica oleracea	31.01	3.00e-49	189.00
IUUC-Bra-017165	Brassica rapa	29.43	9.00e-50	191.00
IUUC-Cel-018131	Caenorhabditis elegans	32.24	1.00e-64	240.00
IUUC-Cja-018898	Callithrix jacchus	82.57	0.00e+00	946.00
IUUC-Cfa-020484	Canis familiaris	91.28	0.00e+00	1093.00
IUUC-Cpo-022156	Cavia porcellus	92.11	0.00e+00	1093.00
IUUC-Csa-024019	Chlorocebus sabaeus	96.10	0.00e+00	1119.00
IUUC-Cho-024311	Choloepus hoffmanni	77.92	0.00e+00	934.00
IUUC-Cin-025260	Ciona intestinalis	37.63	7.00e-97	347.00
IUUC-Csv-025836	Ciona savignyi	43.96	9.00e-48	182.00
IUUC-Dre-027702	Danio rerio	69.98	0.00e+00	844.00
IUUC-Dno-029728	Dasypus novemcinctus	86.72	0.00e+00	1083.00
IUUC-Dor-030587	Dipodomys ordii	80.67	1.00e-102	367.00
IUUC-Dme-031595	Drosophila melanogaster	38.85	5.00e-109	388.00
IUUC-Ete-032969	Echinops telfairi	71.57	0.00e+00	720.00
IUUC-Eca-034214	Equus caballus	91.70	0.00e+00	898.00
IUUC-Eeu-034537	Erinaceus europaeus	83.94	0.00e+00	835.00
IUUC-Fca-036005	Felis catus	86.99	0.00e+00	1018.00
IUUC-Fal-037593	Ficedula albicollis	80.28	0.00e+00	932.00
IUUC-Gmo-039042	Gadus morhua	62.85	0.00e+00	650.00
IUUC-Gga-040986	Gallus gallus	80.29	0.00e+00	1006.00
IUUC-Gac-041351	Gasterosteus aculeatus	68.80	0.00e+00	853.00
IUUC-Gma-043452	Glycine max	29.77	2.00e-53	203.00
IUUC-Ggo-045427	Gorilla gorilla	89.76	0.00e+00	1092.00
IUUC-Hsa-046632	Homo sapiens	92.76	0.00e+00	1107.00
IUUC-Hvu-047655	Hordeum vulgare	24.46	3.00e-26	112.00
IUUC-Lpe-051254	Leersia perrieri	25.81	6.00e-41	161.00
IUUC-Loc-052610	Lepisosteus oculatus	70.90	0.00e+00	852.00
IUUC-Laf-053936	Loxodonta africana	86.54	0.00e+00	1060.00
IUUC-Mcc-055504	Macaca mulatta	86.62	0.00e+00	1104.00
IUUC-Meu-056516	Macropus eugenii	77.92	0.00e+00	940.00
IUUC-Mtr-058062	Medicago truncatula	27.35	7.00e-47	181.00
IUUC-Mga-059777	Meleagris gallopavo	80.53	0.00e+00	981.00
IUUC-Mmr-061298	Microcebus murinus	90.71	0.00e+00	1102.00
IUUC-Mdo-062969	Monodelphis domestica	82.69	0.00e+00	1018.00
IUUC-Mmu-064076	Mus musculus	89.60	0.00e+00	1083.00
IUUC-Mac-065161	Musa acuminata	27.25	1.00e-43	170.00
IUUC-Mpu-066196	Mustela putorius furo	88.62	0.00e+00	1077.00
IUUC-Mlu-067651	Myotis lucifugus	89.66	0.00e+00	1070.00
IUUC-Nle-069853	Nomascus leucogenys	91.28	0.00e+00	1085.00
IUUC-Opr-070350	Ochotona princeps	94.51	3.00e-121	429.00
IUUC-Ont-072489	Oreochromis niloticus	69.61	0.00e+00	849.00
IUUC-Oan-072703	Ornithorhynchus anatinus	78.49	0.00e+00	924.00
IUUC-Ocu-074205	Oryctolagus cuniculus	87.54	0.00e+00	1099.00
IUUC-Oba-075619	Oryza barthii	26.88	6.00e-40	158.00
IUUC-Obr-076632	Oryza brachyantha	24.70	2.00e-39	156.00
IUUC-Ogl-077671	Oryza glaberrima	26.88	5.00e-40	158.00
IUUC-Ogu-078052	Oryza glumaepatula	26.44	5.00e-40	158.00
IUUC-Oin-079611	Oryza indica	26.68	6.00e-38	151.00
IUUC-Olo-080408	Oryza longistaminata	26.76	5.00e-38	151.00
IUUC-Ome-081560	Oryza meridionalis	26.44	5.00e-40	158.00
IUUC-Oni-082145	Oryza nivara	26.88	6.00e-40	158.00
IUUC-Opu-083918	Oryza punctata	27.53	1.00e-37	151.00
IUUC-Oru-084858	Oryza rufipogon	26.68	1.00e-37	150.00
IUUC-Osa-086277	Oryza sativa	26.68	7.00e-38	151.00
IUUC-Ola-086816	Oryzias latipes	67.42	2.00e-90	324.00
IUUC-Olu-087622	Ostreococcus lucimarinus	33.44	1.00e-44	173.00
IUUC-Oga-088765	Otolemur garnettii	95.59	0.00e+00	1065.00
IUUC-Oar-090196	Ovis aries	83.57	0.00e+00	947.00
IUUC-Ptr-091676	Pan troglodytes	92.93	0.00e+00	1108.00
IUUC-Pan-092068	Papio anubis	90.08	0.00e+00	1094.00
IUUC-Psi-093367	Pelodiscus sinensis	82.73	0.00e+00	979.00
IUUC-Ppa-095699	Physcomitrella patens	27.94	4.00e-44	172.00
IUUC-Pfo-096067	Poecilia formosa	69.95	0.00e+00	826.00
IUUC-Pab-098111	Pongo abelii	89.92	0.00e+00	1094.00
IUUC-Pop-099116	Populus trichocarpa	27.25	3.00e-48	186.00
IUUC-Pca-100680	Procavia capensis	78.15	0.00e+00	884.00
IUUC-Ppe-101790	Prunus persica	27.22	5.00e-50	191.00
IUUC-Pva-102871	Pteropus vampyrus	85.69	0.00e+00	994.00
IUUC-Rno-106088	Rattus norvegicus	89.28	0.00e+00	1082.00
IUUC-Sha-106984	Sarcophilus harrisii	85.47	0.00e+00	1010.00
IUUC-Smo-109404	Selaginella moellendorffii	28.34	2.00e-47	183.00
IUUC-Sit-110828	Setaria italica	27.14	2.00e-45	176.00
IUUC-Sly-111009	Solanum lycopersicum	28.14	4.00e-50	192.00
IUUC-Stu-112370	Solanum tuberosum	28.34	2.00e-51	196.00
IUUC-Sar-113659	Sorex araneus	56.38	8.00e-77	280.00
IUUC-Sbi-114819	Sorghum bicolor	28.90	3.00e-43	169.00
IUUC-Ssc-116241	Sus scrofa	88.13	0.00e+00	1049.00
IUUC-Tgu-116576	Taeniopygia guttata	83.55	0.00e+00	1025.00
IUUC-Tru-118336	Takifugu rubripes	61.70	0.00e+00	693.00
IUUC-Tsy-119006	Tarsius syrichta	85.58	0.00e+00	1034.00
IUUC-Tni-120300	Tetraodon nigroviridis	70.18	0.00e+00	828.00
IUUC-Tca-121002	Theobroma cacao	29.37	4.00e-52	198.00
IUUC-Tae-124868	Triticum aestivum	25.41	3.00e-37	149.00
IUUC-Tur-126463	Triticum urartu	25.00	7.00e-37	148.00
IUUC-Tbe-127631	Tupaia belangeri	92.47	0.00e+00	875.00
IUUC-Ttr-129005	Tursiops truncatus	82.92	4.00e-161	561.00
IUUC-Vpa-130246	Vicugna pacos	78.12	0.00e+00	786.00
IUUC-Vvi-130878	Vitis vinifera	27.71	1.00e-48	187.00
IUUC-Xtr-132798	Xenopus tropicalis	70.87	0.00e+00	817.00
IUUC-Xma-133264	Xiphophorus maculatus	69.63	0.00e+00	827.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence