iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073149

UUCD1 version

UUC-OrA-00758

Ensembl Protein ID

ENSOANP00000007311.2

UniProt Accession

F7G1C1; F7G1C1_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE2D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000004612.3	ENSOANT00000007313.3	ENSOANP00000007311.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.10e-54	184.2	7	139
UBD/UBC-like/UBD_UBC	3.30e-82	273.7	6	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
             el++l++dpp+++sa+pv + dl++w+++i+Gp+d+ Y+ggvF l+++fp+dYPfkPPk+ f+tki+hPn+++nG++Cl+il+  ++
   Q: 7    VYELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILR--SQ 92
           5699******************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           Wspal+v++vllsi+sll++pnp++pl  ++a+++k+++e+y++++r
   Q: 93   WSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAR 139
           *******************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 2    ikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqws 90
           i  el+dl+rd++a++sa++v+ddlf+++ati+gppds+y+ggvfflt+++ptdypfkppk+af+tkiyhpninsngsicldilrsqws
   Q: 6    IVYELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWS 94
           6679************************************************************************************* PP
   S: 91   aaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           +alt+skvlls+csll+d++pddplv++ia+iyk+dkeky+r+arewt
   Q: 95   PALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWT 142
           ***********************************************8 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MVVVQIVYEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY 60
PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGTAG TTCAGATAGT TTATTATTAT GGTATTTATT AAGTGCTTAC TGTGTGCCAG 60
GCACTGTCTG ATAGCACCAT GCTAAGCACT GGGATAAATA TGATCAAATC AGGTAAAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001563	Ailuropoda melanoleuca	95.92	2.00e-82	296.00
IUUC-Apl-003639	Anas platyrhynchos	100.00	4.00e-81	292.00
IUUC-Aca-005254	Anolis carolinensis	95.92	2.00e-82	296.00
IUUC-Bta-013467	Bos taurus	95.92	2.00e-82	296.00
IUUC-Cja-019302	Callithrix jacchus	95.92	2.00e-82	296.00
IUUC-Cfa-021087	Canis familiaris	95.92	2.00e-82	296.00
IUUC-Csa-023668	Chlorocebus sabaeus	95.92	2.00e-82	296.00
IUUC-Cho-024987	Choloepus hoffmanni	95.92	2.00e-82	296.00
IUUC-Csv-026311	Ciona savignyi	80.82	2.00e-70	256.00
IUUC-Dno-030067	Dasypus novemcinctus	95.92	2.00e-82	296.00
IUUC-Dor-030474	Dipodomys ordii	95.92	2.00e-82	296.00
IUUC-Ete-032540	Echinops telfairi	95.92	2.00e-82	296.00
IUUC-Eca-034167	Equus caballus	95.92	2.00e-82	296.00
IUUC-Gga-040873	Gallus gallus	95.92	2.00e-82	296.00
IUUC-Hsa-045951	Homo sapiens	95.92	2.00e-82	296.00
IUUC-Itr-048743	Ictidomys tridecemlineatus	95.92	2.00e-82	296.00
IUUC-Laf-053673	Loxodonta africana	94.56	1.00e-81	293.00
IUUC-Mcc-055719	Macaca mulatta	95.92	2.00e-82	296.00
IUUC-Mga-060138	Meleagris gallopavo	100.00	4.00e-81	292.00
IUUC-Mmr-061212	Microcebus murinus	95.92	2.00e-82	296.00
IUUC-Mdo-062402	Monodelphis domestica	95.86	4.00e-81	292.00
IUUC-Mmu-063779	Mus musculus	95.92	2.00e-82	296.00
IUUC-Mpu-065724	Mustela putorius furo	95.92	2.00e-82	296.00
IUUC-Mlu-067573	Myotis lucifugus	100.00	4.00e-81	292.00
IUUC-Nle-069950	Nomascus leucogenys	95.92	2.00e-82	296.00
IUUC-Oga-088915	Otolemur garnettii	95.92	2.00e-82	296.00
IUUC-Oar-090418	Ovis aries	100.00	2.00e-81	293.00
IUUC-Ptr-091575	Pan troglodytes	95.92	2.00e-82	296.00
IUUC-Pan-092922	Papio anubis	95.92	2.00e-82	296.00
IUUC-Pab-098137	Pongo abelii	95.92	2.00e-82	296.00
IUUC-Pca-100678	Procavia capensis	95.92	2.00e-82	296.00
IUUC-Pva-102770	Pteropus vampyrus	95.92	2.00e-82	296.00
IUUC-Rno-106124	Rattus norvegicus	95.92	2.00e-82	296.00
IUUC-Sha-106489	Sarcophilus harrisii	95.86	2.00e-81	293.00
IUUC-Sar-113557	Sorex araneus	100.00	4.00e-81	292.00
IUUC-Tgu-117399	Taeniopygia guttata	97.90	2.00e-81	293.00
IUUC-Ttr-128363	Tursiops truncatus	95.92	2.00e-82	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence