iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003399

Ensembl Protein ID

ENSAPLP00000004493.1

UniProt Accession

U3IB71; U3IB71_ANAPL

Genbank Protein ID

ENSAPLP00000004493

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01144808

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004949.1	ENSAPLT00000005109.1	ENSAPLP00000004493.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-40	134.9	156	197
UBD/Beta-Prp	4.40e-53	180.1	109	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllks 38
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++s
   Q: 156  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCIQS 197
           8***********9644499********************986 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee 131
            +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++ 
   Q: 109  KKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCIQ- 196
           4677889999*********99***************************************9778************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++ hd+ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l 
   Q: 197  SFETHDSDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILF 285
           *******************************************95333556778999******************************** PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsir 247
           gh++ v+ +r+sp+++ + sgs D ++r
   Q: 286  GHENRVSTLRVSPDGTAFCSGSWDHTLR 313
           **********************999976 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

VHQVAERVEA LGQFVMKTRR TLKGHGNKVL CMDWCKDKRR IVSSSQDGKV IVWDSFTTNK 60
EHAVTMPCTW VMACAYAPSG CAIACGGLDN KCSVYPLTFD KNENMAAKKK SVAMHTNYLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCACCAGG TGGCAGAGCG TGTGGAGGCA CTGGGCCAGT TTGTGATGAA GACCAGGAGG 60
ACGCTGAAGG GCCATGGAAA TAAAGTTCTC TGTATGGACT GGTGCAAAGA CAAAAGAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	98.72	0.00e+00	650.00
IUUC-Aca-004861	Anolis carolinensis	98.08	0.00e+00	646.00
IUUC-Ame-011851	Astyanax mexicanus	95.21	0.00e+00	635.00
IUUC-Bta-012438	Bos taurus	98.40	0.00e+00	650.00
IUUC-Cel-018408	Caenorhabditis elegans	66.13	3.00e-128	451.00
IUUC-Cja-019086	Callithrix jacchus	98.72	0.00e+00	651.00
IUUC-Cfa-021255	Canis familiaris	98.72	0.00e+00	649.00
IUUC-Cpo-021398	Cavia porcellus	97.45	0.00e+00	639.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.72	0.00e+00	652.00
IUUC-Cin-025305	Ciona intestinalis	61.88	7.00e-122	429.00
IUUC-Csv-026058	Ciona savignyi	62.19	2.00e-122	431.00
IUUC-Dre-028572	Danio rerio	94.25	0.00e+00	630.00
IUUC-Dno-029958	Dasypus novemcinctus	88.63	1.00e-109	389.00
IUUC-Dor-031013	Dipodomys ordii	98.02	2.00e-149	521.00
IUUC-Dme-031889	Drosophila melanogaster	68.71	1.00e-135	475.00
IUUC-Eca-033977	Equus caballus	98.72	0.00e+00	649.00
IUUC-Eeu-035079	Erinaceus europaeus	98.40	0.00e+00	649.00
IUUC-Fca-035693	Felis catus	98.72	0.00e+00	647.00
IUUC-Fal-037345	Ficedula albicollis	98.72	0.00e+00	651.00
IUUC-Gmo-039222	Gadus morhua	94.57	0.00e+00	629.00
IUUC-Gga-040320	Gallus gallus	99.68	0.00e+00	654.00
IUUC-Gac-042644	Gasterosteus aculeatus	94.25	0.00e+00	629.00
IUUC-Ggo-044489	Gorilla gorilla	99.04	0.00e+00	650.00
IUUC-Hsa-046434	Homo sapiens	98.72	0.00e+00	650.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.61	6.00e-175	605.00
IUUC-Loc-052790	Lepisosteus oculatus	96.81	0.00e+00	640.00
IUUC-Laf-054255	Loxodonta africana	97.44	0.00e+00	642.00
IUUC-Mcc-055610	Macaca mulatta	98.72	0.00e+00	650.00
IUUC-Meu-056819	Macropus eugenii	97.12	3.00e-180	623.00
IUUC-Mga-059740	Meleagris gallopavo	100.00	0.00e+00	653.00
IUUC-Mmr-061221	Microcebus murinus	98.40	0.00e+00	649.00
IUUC-Mdo-062619	Monodelphis domestica	99.36	0.00e+00	653.00
IUUC-Mmu-064266	Mus musculus	98.40	0.00e+00	649.00
IUUC-Mpu-065766	Mustela putorius furo	98.32	1.00e-177	614.00
IUUC-Mlu-067221	Myotis lucifugus	97.13	0.00e+00	639.00
IUUC-Nle-069515	Nomascus leucogenys	99.04	0.00e+00	649.00
IUUC-Opr-070195	Ochotona princeps	88.82	6.00e-163	566.00
IUUC-Ont-071535	Oreochromis niloticus	84.35	5.00e-154	536.00
IUUC-Oan-072899	Ornithorhynchus anatinus	98.37	3.00e-106	376.00
IUUC-Ocu-074666	Oryctolagus cuniculus	98.66	4.00e-178	616.00
IUUC-Ola-086578	Oryzias latipes	94.89	0.00e+00	629.00
IUUC-Oga-089090	Otolemur garnettii	98.10	0.00e+00	645.00
IUUC-Oar-090017	Ovis aries	98.09	0.00e+00	642.00
IUUC-Ptr-091280	Pan troglodytes	98.72	0.00e+00	648.00
IUUC-Pan-092198	Papio anubis	99.04	0.00e+00	648.00
IUUC-Psi-093030	Pelodiscus sinensis	98.72	0.00e+00	647.00
IUUC-Pfo-097182	Poecilia formosa	94.89	0.00e+00	630.00
IUUC-Pab-098157	Pongo abelii	98.72	0.00e+00	653.00
IUUC-Pca-100988	Procavia capensis	72.82	4.00e-122	430.00
IUUC-Pva-102232	Pteropus vampyrus	98.88	4.00e-160	556.00
IUUC-Rno-105526	Rattus norvegicus	94.32	1.00e-178	618.00
IUUC-Sha-106754	Sarcophilus harrisii	99.36	0.00e+00	649.00
IUUC-Ssc-115390	Sus scrofa	98.73	0.00e+00	646.00
IUUC-Tgu-117377	Taeniopygia guttata	99.36	0.00e+00	651.00
IUUC-Tru-117938	Takifugu rubripes	94.89	0.00e+00	629.00
IUUC-Tsy-119392	Tarsius syrichta	84.35	7.00e-151	526.00
IUUC-Tni-119834	Tetraodon nigroviridis	77.96	2.00e-146	511.00
IUUC-Tbe-127469	Tupaia belangeri	96.17	7.00e-178	615.00
IUUC-Ttr-128252	Tursiops truncatus	97.76	0.00e+00	639.00
IUUC-Vpa-130173	Vicugna pacos	90.23	2.00e-136	478.00
IUUC-Xtr-131803	Xenopus tropicalis	97.76	0.00e+00	644.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence