iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053484

UUCD1 version

UUC-LoA-00392

Ensembl Protein ID

ENSLAFP00000009616.2

UniProt Accession

G3T7M1; G3T7M1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000011512.2	ENSLAFT00000011510.2	ENSLAFP00000009616.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	5.70e-17	61.7	376	423

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l+r+ p+SLqh+CR +I++c++++++   d+LP+P+s+k YL++++y+
   Q: 376  STPLIRTFPFSLQHICRTVICNCTTYDGI---DALPIPSSMKLYLKEYHYK 423
           678899***********************...****************985 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

SIENNSKNVD VRPKTSRSRS ADRKDGYVWS GKKLSWLKKS ESCSDAETVD TVEKTEVPLR 60
SQERKHSCSS IELDLDHSCG HRFLGRSLKQ KLQDAVGQCF PIKNCSSRHS SGLPSKRKIH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTATTGAAA ATAATAGTAA AAATGTAGAT GTAAGGCCCA AAACTAGTCG AAGTAGAAGT 60
GCTGACAGAA AGGATGGTTA TGTATGGAGT GGAAAGAAGT TATCTTGGTT AAAAAAAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	95.16	0.00e+00	793.00
IUUC-Apl-003839	Anas platyrhynchos	80.23	0.00e+00	639.00
IUUC-Aca-004840	Anolis carolinensis	79.31	0.00e+00	692.00
IUUC-Bta-012503	Bos taurus	94.48	0.00e+00	787.00
IUUC-Bol-016597	Brassica oleracea	30.38	6.90e-02	32.30
IUUC-Cja-019284	Callithrix jacchus	94.48	0.00e+00	786.00
IUUC-Cfa-020890	Canis familiaris	94.25	0.00e+00	790.00
IUUC-Cpo-022081	Cavia porcellus	78.15	0.00e+00	669.00
IUUC-Csa-023076	Chlorocebus sabaeus	94.71	0.00e+00	793.00
IUUC-Cho-024700	Choloepus hoffmanni	94.25	0.00e+00	832.00
IUUC-Dno-029961	Dasypus novemcinctus	95.40	0.00e+00	833.00
IUUC-Dor-030273	Dipodomys ordii	94.74	0.00e+00	803.00
IUUC-Ete-032972	Echinops telfairi	94.55	5.00e-172	596.00
IUUC-Eca-034289	Equus caballus	94.94	0.00e+00	796.00
IUUC-Eeu-035208	Erinaceus europaeus	91.24	0.00e+00	758.00
IUUC-Fal-036829	Ficedula albicollis	80.23	0.00e+00	639.00
IUUC-Gga-040725	Gallus gallus	79.08	0.00e+00	659.00
IUUC-Ggo-044886	Gorilla gorilla	94.71	0.00e+00	791.00
IUUC-Hsa-046322	Homo sapiens	94.48	0.00e+00	790.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	95.17	0.00e+00	799.00
IUUC-Lch-049459	Latimeria chalumnae	57.83	2.00e-137	481.00
IUUC-Mcc-054890	Macaca mulatta	94.48	0.00e+00	791.00
IUUC-Meu-056532	Macropus eugenii	84.36	0.00e+00	646.00
IUUC-Mtr-057670	Medicago truncatula	36.67	2.00e+00	26.60
IUUC-Mvi-060418	Microbotryum violaceum	32.10	1.40e-02	32.70
IUUC-Mmr-061714	Microcebus murinus	96.32	0.00e+00	803.00
IUUC-Mmu-063161	Mus musculus	89.20	0.00e+00	752.00
IUUC-Mac-064598	Musa acuminata	24.53	7.50e-01	26.90
IUUC-Mpu-066499	Mustela putorius furo	95.17	0.00e+00	823.00
IUUC-Mlu-066945	Myotis lucifugus	93.56	0.00e+00	784.00
IUUC-Nle-069976	Nomascus leucogenys	94.48	0.00e+00	788.00
IUUC-Opr-070255	Ochotona princeps	89.02	0.00e+00	758.00
IUUC-Ocu-074764	Oryctolagus cuniculus	95.19	0.00e+00	802.00
IUUC-Oga-088910	Otolemur garnettii	89.04	0.00e+00	769.00
IUUC-Oar-090330	Ovis aries	94.25	0.00e+00	784.00
IUUC-Ptr-090709	Pan troglodytes	94.71	0.00e+00	791.00
IUUC-Pan-092540	Papio anubis	94.71	0.00e+00	793.00
IUUC-Psi-093678	Pelodiscus sinensis	82.76	0.00e+00	722.00
IUUC-Pfo-097139	Poecilia formosa	80.81	5.00e-87	315.00
IUUC-Pab-097970	Pongo abelii	92.68	0.00e+00	649.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.40e-01	30.80
IUUC-Pca-100211	Procavia capensis	85.13	0.00e+00	683.00
IUUC-Rno-106014	Rattus norvegicus	86.67	0.00e+00	739.00
IUUC-Sha-106822	Sarcophilus harrisii	84.33	0.00e+00	719.00
IUUC-Ssc-115821	Sus scrofa	95.40	0.00e+00	798.00
IUUC-Tgu-117117	Taeniopygia guttata	80.69	0.00e+00	642.00
IUUC-Tsy-118979	Tarsius syrichta	97.45	3.00e-127	447.00
IUUC-Tca-121131	Theobroma cacao	30.77	2.00e-03	36.60
IUUC-Vpa-130626	Vicugna pacos	94.46	0.00e+00	798.00
IUUC-Vvi-131327	Vitis vinifera	43.75	1.00e-01	31.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence