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Tag Content
UUCD2 ID IUUC-Itr-048737
UUCD1 version UUC-SpT-00717
Ensembl Protein ID ENSSTOP00000017009.1
UniProt Accession I3MY14; I3MY14_ICTTR
Genbank Protein ID ENSSTOP00000017009
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AGTP01034852
Gene Name USP44
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000023944.1 ENSSTOT00000022338.1 ENSSTOP00000017009.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 8.00e-97 324.4 271 675
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..........kkkeklneenp..................................... 42
           tGl+NlgNtCYmNSvLQ+Ls++  +r+++l+                    +                                     
   Q: 271  TGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKldlnqwltvtA---------Sdktrsykhppitdtvvyqmnecqekdtglvcsrhpsl 350
           7******************************87765554431.........12344555667888889899999888889999999999 PP
   S: 43   ......................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk 109
                                 +++  +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ lld+++ el  
   Q: 351  ssglsggasksrnmeliqprepSSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRVIPAFRGYAQQDAQEFLCELLDKIQHEL-- 437
           999999998888888888877777777************************************************************.. PP
   S: 110  eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.......slqdcL 191
                  e+++++  +l   +++k  k+  ++++++F+gql sq++cl+cdn+s++ epf+dlsl++p++ + + +        ++++L
   Q: 438  -------ETTGTRLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQFSGKdiasqpcLVTEML 519
           .......7788888999999************************************************8776655577777779***** PP
   S: 192  esftkeeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspe 269
           ++ft++e leg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s   ++reki  +v f ++L+++p+c++++
   Q: 520  AKFTETEVLEGKI-YVCDQCNSKRRrfsskpvvlteAQKQLMICHLPQVLRLHLKRFRWSGC-NNREKIGVHVGFEETLNMEPYCCRET 606
           **********965.*******999999999999999***********************998.7778********************99 PP
   S: 270  ekqke..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
            k+ +  + +Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk + ++++ev++   ++aY+lfY++
   Q: 607  LKSLRpeCFIYDLSAVVMHHGkGFGSGHYTAYCYNSEGGfWVHCNDSKLSMCTMDEVCK---AQAYILFYTQ 675
           88876779***************************9999********************...********98 PP
   
Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MLTMDKCKHV GQLQLAPDHS ILNPQKWYCV DCNTTESIWA CLSCSHVACG RYIEEHALKH 60
FQESSHPVAL EVNEMYVFCY LCDDYVLNDN ATGDLKLLRS TLSAIKSQNY HSTTRSGRVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-048737|DUB,USP|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCTAACAA TGGATAAGTG CAAACACGTT GGGCAGTTGC AGCTTGCTCC AGACCATTCC 60
ATCCTCAATC CTCAGAAATG GTATTGTGTG GACTGCAATA CAACTGAATC TATTTGGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-048737|DUB,USP|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:1904667--P:negative regulation of ubiquitin protein ligase activity
GO:0016579--P:protein deubiquitination
GO:0090231--P:regulation of spindle checkpoint
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001220 Ailuropoda melanoleuca 91.57 0.00e+00 1289.00
IUUC-Apl-003673 Anas platyrhynchos 75.87 0.00e+00 1035.00
IUUC-Aca-004434 Anolis carolinensis 73.18 0.00e+00 1014.00
IUUC-Ame-010986 Astyanax mexicanus 64.71 0.00e+00 868.00
IUUC-Bta-012774 Bos taurus 89.47 0.00e+00 1242.00
IUUC-Cja-019619 Callithrix jacchus 89.47 0.00e+00 1252.00
IUUC-Cfa-020957 Canis familiaris 91.01 0.00e+00 1300.00
IUUC-Csa-023177 Chlorocebus sabaeus 88.78 0.00e+00 1243.00
IUUC-Cho-024877 Choloepus hoffmanni 89.68 0.00e+00 857.00
IUUC-Csv-025814 Ciona savignyi 44.54 2.00e-153 536.00
IUUC-Dre-027878 Danio rerio 64.92 0.00e+00 840.00
IUUC-Dno-029832 Dasypus novemcinctus 91.42 0.00e+00 1296.00
IUUC-Ete-032627 Echinops telfairi 86.80 0.00e+00 1216.00
IUUC-Eca-033863 Equus caballus 84.08 0.00e+00 1178.00
IUUC-Eeu-035225 Erinaceus europaeus 83.03 0.00e+00 1156.00
IUUC-Fca-036288 Felis catus 91.01 0.00e+00 1288.00
IUUC-Fal-037207 Ficedula albicollis 74.26 0.00e+00 999.00
IUUC-Gga-040457 Gallus gallus 73.34 0.00e+00 1002.00
IUUC-Ggo-044926 Gorilla gorilla 89.89 0.00e+00 1252.00
IUUC-Hsa-046079 Homo sapiens 89.75 0.00e+00 1254.00
IUUC-Lch-050260 Latimeria chalumnae 67.77 0.00e+00 910.00
IUUC-Laf-054491 Loxodonta africana 88.86 0.00e+00 1187.00
IUUC-Mcc-055694 Macaca mulatta 89.48 0.00e+00 1253.00
IUUC-Mga-059523 Meleagris gallopavo 73.31 0.00e+00 1023.00
IUUC-Mmr-060885 Microcebus murinus 92.43 0.00e+00 1282.00
IUUC-Mdo-063018 Monodelphis domestica 79.10 0.00e+00 1083.00
IUUC-Mmu-064012 Mus musculus 80.59 0.00e+00 1083.00
IUUC-Mpu-066207 Mustela putorius furo 90.17 0.00e+00 1303.00
IUUC-Mlu-066929 Myotis lucifugus 86.92 0.00e+00 1175.00
IUUC-Nle-069313 Nomascus leucogenys 80.31 0.00e+00 1075.00
IUUC-Opr-070375 Ochotona princeps 80.06 0.00e+00 1113.00
IUUC-Ont-071637 Oreochromis niloticus 61.66 0.00e+00 847.00
IUUC-Oan-073030 Ornithorhynchus anatinus 77.49 0.00e+00 833.00
IUUC-Ocu-074836 Oryctolagus cuniculus 86.88 0.00e+00 1206.00
IUUC-Oga-088367 Otolemur garnettii 91.44 0.00e+00 1251.00
IUUC-Oar-089953 Ovis aries 90.17 0.00e+00 1286.00
IUUC-Ptr-090980 Pan troglodytes 89.75 0.00e+00 1253.00
IUUC-Pan-092748 Papio anubis 89.48 0.00e+00 1248.00
IUUC-Psi-094078 Pelodiscus sinensis 75.78 0.00e+00 833.00
IUUC-Pab-098514 Pongo abelii 89.76 0.00e+00 1247.00
IUUC-Pva-102984 Pteropus vampyrus 89.33 0.00e+00 1258.00
IUUC-Rno-106019 Rattus norvegicus 79.83 0.00e+00 1125.00
IUUC-Sha-106965 Sarcophilus harrisii 77.97 0.00e+00 1080.00
IUUC-Ssc-115299 Sus scrofa 91.15 0.00e+00 1300.00
IUUC-Tgu-117160 Taeniopygia guttata 74.01 0.00e+00 1001.00
IUUC-Tru-118156 Takifugu rubripes 60.70 0.00e+00 826.00
IUUC-Tni-119733 Tetraodon nigroviridis 61.44 0.00e+00 840.00
IUUC-Tbe-128084 Tupaia belangeri 83.99 0.00e+00 1186.00
IUUC-Ttr-128928 Tursiops truncatus 92.41 0.00e+00 1308.00
IUUC-Vpa-130706 Vicugna pacos 90.87 0.00e+00 1276.00
IUUC-Xtr-132061 Xenopus tropicalis 71.08 0.00e+00 935.00
Created Date 25-Jun-2017

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