iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000023571.2	ENSGALT00000039192.1	ENSGALP00000038403.1
ENSGALG00000023571.2	ENSGALT00000078299.1	ENSGALP00000056956.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.7	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+ +     + s +f+          CP Cr
   Q: 10   CSICYSLFED-PRVLPCSHTFCRSCLEGV----IQLSSNFSiwrplrvplkCPNCR 60
           **********.**************9877....334444434666677777**998 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MHQFEEELTC SICYSLFEDP RVLPCSHTFC RSCLEGVIQL SSNFSIWRPL RVPLKCPNCR 60
SIVEIPASGT ESLPINFALK AIIEKYRQED HSDVATCSEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCGCGTG CCGACCGTTT ACTTTCGAAC GGCGCGGCCG TTGGCGCTGT GGCGCATGCG 60
CGGCTCGGCG CGCTGAGGAG AGCGGCGGGG CCGTGAGGGG CGGCCGGCGC GGTGAGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	57.88	6.00e-135	473.00
IUUC-Apl-003996	Anas platyrhynchos	79.66	2.00e-175	607.00
IUUC-Aca-005141	Anolis carolinensis	63.21	2.00e-150	525.00
IUUC-Ame-011353	Astyanax mexicanus	53.27	2.00e-102	365.00
IUUC-Bta-013440	Bos taurus	62.43	1.00e-131	462.00
IUUC-Cfa-021168	Canis familiaris	57.88	2.00e-137	481.00
IUUC-Cpo-021702	Cavia porcellus	54.98	7.00e-123	433.00
IUUC-Csa-024141	Chlorocebus sabaeus	57.14	1.00e-119	422.00
IUUC-Dre-028408	Danio rerio	46.25	6.00e-84	304.00
IUUC-Dno-029180	Dasypus novemcinctus	58.37	1.00e-134	472.00
IUUC-Eca-034357	Equus caballus	56.90	2.00e-131	461.00
IUUC-Fca-036287	Felis catus	58.52	6.00e-136	476.00
IUUC-Ggo-045307	Gorilla gorilla	57.88	6.00e-129	453.00
IUUC-Hsa-045690	Homo sapiens	58.13	8.00e-130	456.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	57.11	2.00e-135	474.00
IUUC-Laf-054522	Loxodonta africana	57.39	2.00e-135	474.00
IUUC-Mcc-055145	Macaca mulatta	57.88	1.00e-129	456.00
IUUC-Mmr-061197	Microcebus murinus	58.37	1.00e-136	479.00
IUUC-Mmu-064217	Mus musculus	57.84	1.00e-131	462.00
IUUC-Mpu-065691	Mustela putorius furo	58.13	1.00e-136	479.00
IUUC-Mlu-067742	Myotis lucifugus	56.90	4.00e-129	454.00
IUUC-Nle-069722	Nomascus leucogenys	58.13	2.00e-136	478.00
IUUC-Oan-073382	Ornithorhynchus anatinus	57.21	1.00e-130	459.00
IUUC-Oar-089206	Ovis aries	57.88	2.00e-135	475.00
IUUC-Pan-092189	Papio anubis	58.13	3.00e-130	458.00
IUUC-Psi-093523	Pelodiscus sinensis	73.04	5.00e-165	573.00
IUUC-Pma-094162	Petromyzon marinus	34.06	1.00e-49	190.00
IUUC-Pfo-096032	Poecilia formosa	47.56	5.00e-90	324.00
IUUC-Pva-103089	Pteropus vampyrus	57.64	2.00e-129	455.00
IUUC-Rno-105440	Rattus norvegicus	56.40	7.00e-132	463.00
IUUC-Ssc-115809	Sus scrofa	55.67	6.00e-124	436.00
IUUC-Tru-118402	Takifugu rubripes	46.50	3.00e-90	324.00
IUUC-Tni-119737	Tetraodon nigroviridis	42.86	1.00e-84	305.00
IUUC-Ttr-128921	Tursiops truncatus	57.88	1.00e-129	455.00
IUUC-Vpa-130397	Vicugna pacos	57.74	2.00e-135	475.00
IUUC-Xtr-132752	Xenopus tropicalis	56.17	5.00e-93	334.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence