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Tag Content
UUCD2 ID IUUC-Dre-028662
UUCD1 version UUC-DaR-00428
Ensembl Protein ID ENSDARP00000079663.5
UniProt Accession E7FAU9; E7FAU9_DANRE
Genbank Protein ID ENSDARP00000079663
Protein Name Phosphoinositide-3-kinase, regulatory subunit 4
Genbank Nucleotide ID CR942305
Gene Name pik3r4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000060469.6 ENSDART00000133310.2 ENSDARP00000115670.1
ENSDARG00000060469.6 ENSDART00000085228.5 ENSDARP00000079663.5
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-20 73.5 977 1006
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclafsd..tllvsGsdDgtikvWD 29
           H++ v+ ++ sd   +++++s+Dgt+k+WD
   Q: 977  HKSAVNRIRVSDehSIFATCSNDGTVKIWD 1006
           99999999995546779************* PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MGNQLAGIAP SQILSVDSYF SDIHDYEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60
SLPLTSYKQE VEELKIRLHS CQNCLPFQKA TLTEKAAILF RQYVRDNLYD RISTRPFLNN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028662|E3,WD_repeat|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GACCTCAGTT CAGGCAGTAT AGACGCAAAA CACAGTTTCA CCGCTTATAC AGTAACAACA 60
CGCGAAACAG CTCATTTGTG TAAATATCTG TTTATTGTAT TGTTCGTGTG ATTTGATATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028662|E3,WD_repeat|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00069--Pkinase
PF00400--WD40
SMART

SM00220--S_TKc
SM00320--WD40
Gene Ontology

GO:0005770--C:late endosome
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000213 Aegilops tauschii 32.82 6.00e-47 183.00
IUUC-Aml-001659 Ailuropoda melanoleuca 82.07 0.00e+00 2285.00
IUUC-Atr-002968 Amborella trichopoda 47.08 5.00e-48 187.00
IUUC-Apl-003418 Anas platyrhynchos 82.70 0.00e+00 2370.00
IUUC-Aca-004344 Anolis carolinensis 82.62 0.00e+00 2134.00
IUUC-Aly-006107 Arabidopsis lyrata 47.69 1.00e-71 265.00
IUUC-Ath-007260 Arabidopsis thaliana 48.00 3.00e-72 268.00
IUUC-Ago-007721 Ashbya gossypii 28.43 3.00e-96 347.00
IUUC-Acl-008378 Aspergillus clavatus 37.09 1.00e-152 534.00
IUUC-Afl-008632 Aspergillus flavus 35.54 6.00e-144 506.00
IUUC-Afu-009020 Aspergillus fumigatus 36.00 2.00e-145 511.00
IUUC-Ani-009204 Aspergillus nidulans 36.00 7.00e-136 479.00
IUUC-Ang-009811 Aspergillus niger 34.54 3.00e-140 493.00
IUUC-Aor-010168 Aspergillus oryzae 35.54 6.00e-144 506.00
IUUC-Ate-010556 Aspergillus terreus 36.36 5.00e-146 513.00
IUUC-Ame-011955 Astyanax mexicanus 90.16 0.00e+00 2059.00
IUUC-Bgr-012050 Blumeria graminis 36.04 1.00e-139 491.00
IUUC-Bta-012432 Bos taurus 81.34 0.00e+00 2313.00
IUUC-Bci-013846 Botrytis cinerea 35.27 2.00e-142 501.00
IUUC-Bdi-015072 Brachypodium distachyon 41.82 1.00e-69 258.00
IUUC-Bol-015314 Brassica oleracea 48.92 3.00e-73 271.00
IUUC-Bra-017476 Brassica rapa 48.92 3.00e-73 271.00
IUUC-Cel-018550 Caenorhabditis elegans 32.26 5.00e-87 316.00
IUUC-Cja-019538 Callithrix jacchus 81.07 0.00e+00 2299.00
IUUC-Cfa-020483 Canis familiaris 81.92 0.00e+00 2291.00
IUUC-Cpo-021392 Cavia porcellus 81.65 0.00e+00 2309.00
IUUC-Csa-024112 Chlorocebus sabaeus 81.73 0.00e+00 2316.00
IUUC-Cho-025015 Choloepus hoffmanni 76.54 0.00e+00 814.00
IUUC-Cin-025209 Ciona intestinalis 41.97 0.00e+00 1083.00
IUUC-Csv-026334 Ciona savignyi 41.98 0.00e+00 896.00
IUUC-Cgl-026447 Colletotrichum gloeosporioides 35.54 9.00e-145 509.00
IUUC-Cne-026999 Cryptococcus neoformans 38.87 5.00e-122 432.00
IUUC-Dno-029545 Dasypus novemcinctus 80.25 0.00e+00 2259.00
IUUC-Dor-030941 Dipodomys ordii 59.89 0.00e+00 660.00
IUUC-Dse-031455 Dothistroma septosporum 38.16 9.00e-139 488.00
IUUC-Dme-031726 Drosophila melanogaster 46.69 0.00e+00 750.00
IUUC-Ete-033147 Echinops telfairi 81.38 0.00e+00 886.00
IUUC-Eca-034025 Equus caballus 81.78 0.00e+00 2315.00
IUUC-Eeu-034480 Erinaceus europaeus 76.81 0.00e+00 1308.00
IUUC-Fca-035741 Felis catus 81.78 0.00e+00 2298.00
IUUC-Fal-037666 Ficedula albicollis 81.66 0.00e+00 2340.00
IUUC-Fox-037818 Fusarium oxysporum 34.37 2.00e-130 461.00
IUUC-Fso-038086 Fusarium solani 34.51 2.00e-133 471.00
IUUC-Gmo-038804 Gadus morhua 90.59 0.00e+00 823.00
IUUC-Ggr-039800 Gaeumannomyces graminis 35.55 1.00e-136 481.00
IUUC-Gga-041251 Gallus gallus 81.08 0.00e+00 1829.00
IUUC-Gac-042376 Gasterosteus aculeatus 85.68 0.00e+00 2442.00
IUUC-Gma-044095 Glycine max 45.38 1.00e-73 272.00
IUUC-Ggo-044506 Gorilla gorilla 81.21 0.00e+00 2299.00
IUUC-Hsa-045871 Homo sapiens 81.71 0.00e+00 2316.00
IUUC-Hvu-047648 Hordeum vulgare 32.19 5.00e-48 186.00
IUUC-Itr-048082 Ictidomys tridecemlineatus 84.64 0.00e+00 1047.00
IUUC-Kpa-049390 Komagataella pastoris 27.16 4.00e-146 513.00
IUUC-Lch-050284 Latimeria chalumnae 82.96 0.00e+00 2310.00
IUUC-Lpe-050880 Leersia perrieri 42.64 5.00e-65 243.00
IUUC-Loc-052815 Lepisosteus oculatus 87.17 0.00e+00 2491.00
IUUC-Lma-053324 Leptosphaeria maculans 36.75 3.00e-144 507.00
IUUC-Laf-054204 Loxodonta africana 71.78 0.00e+00 1954.00
IUUC-Mcc-054612 Macaca mulatta 81.58 0.00e+00 2309.00
IUUC-Meu-056227 Macropus eugenii 73.90 0.00e+00 734.00
IUUC-Mor-057094 Magnaporthe oryzae 36.41 1.00e-136 481.00
IUUC-Mtr-058550 Medicago truncatula 45.68 2.00e-73 271.00
IUUC-Mla-058893 Melampsora laricipopulina 36.30 4.00e-134 473.00
IUUC-Mga-059474 Meleagris gallopavo 81.67 0.00e+00 2221.00
IUUC-Mvi-060227 Microbotryum violaceum 46.65 9.00e-84 306.00
IUUC-Mmr-061543 Microcebus murinus 78.04 0.00e+00 2102.00
IUUC-Mdo-062129 Monodelphis domestica 82.16 0.00e+00 2246.00
IUUC-Mmu-064381 Mus musculus 80.49 0.00e+00 2278.00
IUUC-Mac-064455 Musa acuminata 38.64 6.00e-126 446.00
IUUC-Mpu-066151 Mustela putorius furo 84.79 0.00e+00 849.00
IUUC-Mlu-067824 Myotis lucifugus 81.63 0.00e+00 2314.00
IUUC-Nfi-068241 Neosartorya fischeri 36.29 1.00e-147 518.00
IUUC-Ncr-068964 Neurospora crassa 36.40 1.00e-141 498.00
IUUC-Nle-069152 Nomascus leucogenys 81.58 0.00e+00 2310.00
IUUC-Opr-070870 Ochotona princeps 76.35 0.00e+00 1298.00
IUUC-Ont-071293 Oreochromis niloticus 86.84 0.00e+00 2488.00
IUUC-Oan-072852 Ornithorhynchus anatinus 77.80 0.00e+00 2174.00
IUUC-Ocu-074727 Oryctolagus cuniculus 81.58 0.00e+00 2284.00
IUUC-Oba-075932 Oryza barthii 37.99 2.00e-64 241.00
IUUC-Obr-076424 Oryza brachyantha 46.44 4.00e-65 244.00
IUUC-Ogl-077491 Oryza glaberrima 37.99 2.00e-64 241.00
IUUC-Ogu-078933 Oryza glumaepatula 34.71 3.00e-114 407.00
IUUC-Oin-079604 Oryza indica 42.01 5.00e-70 259.00
IUUC-Olo-080850 Oryza longistaminata 35.91 9.00e-118 418.00
IUUC-Ome-081860 Oryza meridionalis 42.01 5.00e-70 260.00
IUUC-Oni-082895 Oryza nivara 37.99 3.00e-64 241.00
IUUC-Opu-083741 Oryza punctata 41.19 1.00e-69 259.00
IUUC-Oru-084616 Oryza rufipogon 37.71 7.00e-64 239.00
IUUC-Osa-085941 Oryza sativa 30.61 1.00e-38 154.00
IUUC-Ola-087357 Oryzias latipes 93.79 2.00e-175 608.00
IUUC-Olu-087659 Ostreococcus lucimarinus 30.39 7.00e-92 332.00
IUUC-Oga-088555 Otolemur garnettii 81.51 0.00e+00 2291.00
IUUC-Oar-089304 Ovis aries 83.60 0.00e+00 1167.00
IUUC-Ptr-091140 Pan troglodytes 81.63 0.00e+00 2315.00
IUUC-Pan-092413 Papio anubis 81.33 0.00e+00 2208.00
IUUC-Psi-093210 Pelodiscus sinensis 82.81 0.00e+00 2357.00
IUUC-Pma-094674 Petromyzon marinus 56.27 0.00e+00 731.00
IUUC-Pno-094969 Phaeosphaeria nodorum 30.29 1.00e-146 514.00
IUUC-Ppa-096017 Physcomitrella patens 46.97 9.00e-78 286.00
IUUC-Pfo-096077 Poecilia formosa 87.31 0.00e+00 2434.00
IUUC-Pab-098269 Pongo abelii 80.93 0.00e+00 2296.00
IUUC-Pop-100052 Populus trichocarpa 44.66 5.00e-64 240.00
IUUC-Pca-100377 Procavia capensis 78.25 0.00e+00 2093.00
IUUC-Ppe-101445 Prunus persica 28.78 1.00e-97 352.00
IUUC-Pva-102198 Pteropus vampyrus 82.53 0.00e+00 1514.00
IUUC-Pgr-103544 Puccinia graminis 50.16 5.00e-86 313.00
IUUC-Ptt-103964 Puccinia triticina 49.20 3.00e-82 301.00
IUUC-Pte-104196 Pyrenophora teres 36.58 6.00e-140 492.00
IUUC-Pyt-104544 Pyrenophora triticirepentis 36.46 2.00e-137 484.00
IUUC-Rno-105256 Rattus norvegicus 80.49 0.00e+00 2280.00
IUUC-Sce-106295 Saccharomyces cerevisiae 41.62 2.00e-74 275.00
IUUC-Sha-107597 Sarcophilus harrisii 82.26 0.00e+00 2308.00
IUUC-Sja-107781 Schizosaccharomyces japonicus 32.68 6.00e-110 392.00
IUUC-Spo-108031 Schizosaccharomyces pombe 46.04 2.00e-77 285.00
IUUC-Ssl-108579 Sclerotinia sclerotiorum 35.69 2.00e-136 481.00
IUUC-Smo-108679 Selaginella moellendorffii 27.97 5.00e-88 320.00
IUUC-Sit-110765 Setaria italica 41.57 6.00e-66 246.00
IUUC-Sly-111527 Solanum lycopersicum 44.88 6.00e-74 273.00
IUUC-Stu-112899 Solanum tuberosum 44.88 1.00e-73 272.00
IUUC-Sar-112986 Sorex araneus 81.27 0.00e+00 2290.00
IUUC-Sbi-114604 Sorghum bicolor 41.89 2.00e-68 255.00
IUUC-Sre-115191 Sporisorium reilianum 45.62 1.00e-70 263.00
IUUC-Ssc-115440 Sus scrofa 81.01 0.00e+00 2273.00
IUUC-Tgu-116633 Taeniopygia guttata 82.17 0.00e+00 2362.00
IUUC-Tru-118439 Takifugu rubripes 86.17 0.00e+00 2467.00
IUUC-Tsy-119472 Tarsius syrichta 73.23 0.00e+00 1153.00
IUUC-Tni-119808 Tetraodon nigroviridis 80.19 0.00e+00 2228.00
IUUC-Tca-121648 Theobroma cacao 48.94 6.00e-75 276.00
IUUC-Tre-122161 Trichoderma reesei 32.37 2.00e-126 447.00
IUUC-Tvi-122575 Trichoderma virens 32.84 4.00e-118 420.00
IUUC-Tae-123381 Triticum aestivum 46.60 3.00e-70 260.00
IUUC-Tur-126291 Triticum urartu 43.37 7.00e-70 259.00
IUUC-Tme-126979 Tuber melanosporum 37.18 2.00e-151 531.00
IUUC-Tbe-127576 Tupaia belangeri 73.12 0.00e+00 832.00
IUUC-Ttr-129106 Tursiops truncatus 85.22 0.00e+00 1155.00
IUUC-Uma-129633 Ustilago maydis 44.69 7.00e-79 290.00
IUUC-Vda-130001 Verticillium dahliae 34.51 6.00e-129 456.00
IUUC-Vpa-130733 Vicugna pacos 71.79 0.00e+00 1036.00
IUUC-Vvi-131318 Vitis vinifera 46.83 6.00e-72 266.00
IUUC-Xtr-131908 Xenopus tropicalis 80.56 0.00e+00 2309.00
IUUC-Xma-133331 Xiphophorus maculatus 87.68 0.00e+00 2456.00
IUUC-Yli-134651 Yarrowia lipolytica 36.94 8.00e-124 438.00
IUUC-Zma-135850 Zea mays 40.41 1.00e-67 252.00
Created Date 25-Jun-2017

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