iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055286

UUCD1 version

UUC-MaM-01110

Ensembl Protein ID

ENSMMUP00000001120.2

UniProt Accession

F6Q231; F6Q231_MACMU

Genbank Protein ID

AFE80512.1; AFH34327.1; EHH26211.1

Protein Name

Putative uncharacterized protein; Ubiquitin carboxyl-terminal hydrolase 38

Genbank Nucleotide ID

JSUE03034659; JU477523; CM001257

Gene Name

USP38; EGK_16123

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000827.3	ENSMMUT00000001193.3	ENSMMUP00000001120.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.20e-83	280.8	445	948

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e  e ++++l++         +  +++ ++k+li+++F+g+l+++i cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlkvQSSHKPSEILECSETSLQEVaskaavltETPRTTDSEKTLIEKMFGGKLRTHICCLNCRSTSQKVE 611
           *****************9557777788888888888888888789999999999999999***************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  ++ ++++                                                                       
   Q: 612  AFTDLSLAFCPSSLENMSfqdpasspstqdgglmqaaipspseepvvynpttaaficdsvvnertigsppnefycsentsvpnesnril 700
           *************98888*********************************************************************** PP
   S: 186  ...............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
                          s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl L
   Q: 701  vnkdvpqkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVL 789
           ****************************************************************************************9 PP
   S: 260  dlspfcts...............................peekqkekkkYeLiavvvHsG.slssGHYvayvkn............... 301
           +l    t+                               +e + ++ + Y L++vvvHsG s++sGHY++y++n               
   Q: 790  ELPVKRTTsfsslseswsvdvdftdlsenlakklkpsgtDEASCTKLVPYLLSSVVVHSGiSSESGHYYSYARNitgtessyqiyhqse 878
           99964444466677777777777777777777776666644444559****************************************** PP
   S: 302  .............................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                         +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 879  alalassqshllgrespsavfeqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 948
           *****9999999999999999988865544555*******************999************986 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRKVVESAE HWLDEAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLH QGYHSLDRKD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGG CCTTGTGAGT TCTTCGCATC CCCTGCCCCT CAAGCGGGTG 60
ATTGTGCGGA AGGTGGTGGA ATCGGCGGAG CACTGGCTAG ACGAGGCGCA GTGCGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mcc:700235

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	93.31	0.00e+00	1862.00
IUUC-Apl-003435	Anas platyrhynchos	76.65	0.00e+00	1272.00
IUUC-Aca-004556	Anolis carolinensis	71.08	0.00e+00	1308.00
IUUC-Ame-010616	Astyanax mexicanus	62.21	0.00e+00	1229.00
IUUC-Bta-013544	Bos taurus	92.90	0.00e+00	1826.00
IUUC-Cja-018745	Callithrix jacchus	94.55	0.00e+00	1921.00
IUUC-Cfa-020434	Canis familiaris	89.73	0.00e+00	1792.00
IUUC-Cpo-021666	Cavia porcellus	92.23	0.00e+00	1790.00
IUUC-Csa-023965	Chlorocebus sabaeus	99.71	0.00e+00	2062.00
IUUC-Cho-024809	Choloepus hoffmanni	84.23	0.00e+00	1284.00
IUUC-Cin-025604	Ciona intestinalis	37.39	5.00e-41	161.00
IUUC-Csv-026333	Ciona savignyi	44.25	8.00e-32	130.00
IUUC-Dre-028338	Danio rerio	62.87	0.00e+00	1248.00
IUUC-Dno-029372	Dasypus novemcinctus	92.13	0.00e+00	1858.00
IUUC-Dor-030752	Dipodomys ordii	89.73	0.00e+00	1248.00
IUUC-Dme-031871	Drosophila melanogaster	25.96	5.00e-56	213.00
IUUC-Ete-032588	Echinops telfairi	79.74	0.00e+00	1134.00
IUUC-Eca-034416	Equus caballus	94.43	0.00e+00	1955.00
IUUC-Eeu-035132	Erinaceus europaeus	74.15	0.00e+00	1407.00
IUUC-Fca-036137	Felis catus	93.86	0.00e+00	1903.00
IUUC-Fal-037297	Ficedula albicollis	76.07	0.00e+00	1450.00
IUUC-Gmo-038727	Gadus morhua	65.87	0.00e+00	1016.00
IUUC-Gga-041091	Gallus gallus	74.12	0.00e+00	1399.00
IUUC-Gac-042082	Gasterosteus aculeatus	62.78	0.00e+00	1132.00
IUUC-Ggo-045376	Gorilla gorilla	93.21	0.00e+00	1857.00
IUUC-Hsa-046444	Homo sapiens	98.18	0.00e+00	1998.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	93.47	0.00e+00	1915.00
IUUC-Lch-050500	Latimeria chalumnae	72.06	0.00e+00	1442.00
IUUC-Loc-052625	Lepisosteus oculatus	64.83	0.00e+00	1302.00
IUUC-Laf-053689	Loxodonta africana	92.88	0.00e+00	1881.00
IUUC-Mga-059905	Meleagris gallopavo	74.45	0.00e+00	1232.00
IUUC-Mmr-061397	Microcebus murinus	95.11	0.00e+00	1910.00
IUUC-Mdo-062833	Monodelphis domestica	86.32	0.00e+00	1797.00
IUUC-Mmu-063157	Mus musculus	90.69	0.00e+00	1834.00
IUUC-Mpu-066434	Mustela putorius furo	94.24	0.00e+00	1924.00
IUUC-Mlu-068178	Myotis lucifugus	91.88	0.00e+00	1810.00
IUUC-Nle-070153	Nomascus leucogenys	97.79	0.00e+00	1934.00
IUUC-Ont-072330	Oreochromis niloticus	63.62	0.00e+00	1251.00
IUUC-Oan-072709	Ornithorhynchus anatinus	81.03	0.00e+00	1291.00
IUUC-Ocu-074832	Oryctolagus cuniculus	94.24	0.00e+00	1894.00
IUUC-Ola-087003	Oryzias latipes	56.16	6.00e-50	189.00
IUUC-Oga-088517	Otolemur garnettii	90.35	0.00e+00	1804.00
IUUC-Oar-089472	Ovis aries	89.16	0.00e+00	1753.00
IUUC-Ptr-090996	Pan troglodytes	97.79	0.00e+00	1991.00
IUUC-Pan-091837	Papio anubis	97.62	0.00e+00	2008.00
IUUC-Psi-093236	Pelodiscus sinensis	76.81	0.00e+00	1165.00
IUUC-Pma-094349	Petromyzon marinus	53.14	0.00e+00	982.00
IUUC-Pfo-097193	Poecilia formosa	62.21	0.00e+00	1157.00
IUUC-Pab-098710	Pongo abelii	97.89	0.00e+00	2010.00
IUUC-Pca-100794	Procavia capensis	81.88	0.00e+00	1640.00
IUUC-Pva-102722	Pteropus vampyrus	92.81	0.00e+00	1890.00
IUUC-Rno-105743	Rattus norvegicus	89.92	0.00e+00	1798.00
IUUC-Sha-106563	Sarcophilus harrisii	85.25	0.00e+00	1447.00
IUUC-Sar-113533	Sorex araneus	77.74	0.00e+00	1561.00
IUUC-Ssc-116259	Sus scrofa	83.84	0.00e+00	1586.00
IUUC-Tgu-117475	Taeniopygia guttata	75.89	0.00e+00	1316.00
IUUC-Tru-118623	Takifugu rubripes	63.08	0.00e+00	1156.00
IUUC-Tsy-119250	Tarsius syrichta	93.49	0.00e+00	1498.00
IUUC-Tni-120441	Tetraodon nigroviridis	58.44	0.00e+00	1068.00
IUUC-Tbe-127936	Tupaia belangeri	81.57	0.00e+00	1546.00
IUUC-Ttr-128483	Tursiops truncatus	80.82	0.00e+00	1418.00
IUUC-Vpa-130303	Vicugna pacos	97.94	0.00e+00	1077.00
IUUC-Xtr-132773	Xenopus tropicalis	73.10	0.00e+00	1426.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence