iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047227

Ensembl Protein ID

MLOC_11046.1

UniProt Accession

M0UHT4; M0UHT4_HORVV

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_11046	MLOC_11046.1	MLOC_11046.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	5.30e-123	411.2	127	435
E3 adaptor/Cullin RING/DCX/DWD	1.40e-23	83.0	262	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltg.hs 96
           e+ ldap++ dd+ylnLldW+s nvl++aLg++vylw+a++g+ s+l  + e++  vtsvsw ++g+++a+G ++++v+i+D ++++ +rtl+g h 
   Q: 127  ERTLDAPDIVDDYYLNLLDWGSANVLSIALGNTVYLWDAASGSTSELVTIgEDDGPVTSVSWAPDGNHIAIGLNSSAVQIWDSSSSQLLRTLQGvHE 223
           689***********************************************666778************************************76478 PP
   S: 97   arvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.........Plkkfkehkaavka 184
            rvg+L+Wn+++l++G+ dg+i+ +d+r++++ ++t+++h+qevCGlkw+ ++++LasGGnDn +++wd s  +          l+++++h+aavka
   Q: 224  LRVGSLAWNKNILTAGGMDGKIVNNDLRIRNHAVQTYRGHEQEVCGLKWSGSGQQLASGGNDNLLHIWDVSMAStaqsagrtqWLHRMEDHSAAVKA 320
           8********************************************************************9877667788887788999********* PP
   S: 185  iawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgea 281
           +aw+P+q++lLasGGG++Drcikfwnt tga+l+++dtgsqvc llw k+ +el+s+hGf++n++tlwkyps++k+ael+gh++Rvl +a spdg +
   Q: 321  LAWCPFQSNLLASGGGANDRCIKFWNTHTGACLNSVDTGSQVCALLWNKNDRELLSSHGFTQNQLTLWKYPSMTKMAELNGHTSRVLFMAQSPDGCT 417
           ************************************************************************************************* PP
   S: 282  ivtaagDetlrfwklfdk 299
           +++aa+Detlrfw++f +
   Q: 418  VASAAADETLRFWNVFGT 435
           ****************76 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           gH+ +v++l++  s+  l+sG++D+ +++WD++
   Q: 262  GHEQEVCGLKWsgSGQQLASGGNDNLLHIWDVS 294
           8**********976699**************85 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MPPMLQEPGS RPRPYMPSLC STPRNPAVKC YGDRFIPDRS AMDMDMAHYL LTEPRKDSKN 60
AVTPSPAKEA YRKLLAEKLL NNRTRILAFR NKPPEPENSM LMELHADAAS IQARPVKKRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGGAGGCC GGCTCGACGC CCTCGATGCC GCCGATGCTC CAGGAGCCCG GGTCGAGGCC 60
TAGGCCCTAC ATGCCGTCCC TCTGCTCCAC GCCCCGCAAC CCTGCCGTCA AGTGCTATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000194	Aegilops tauschii	89.43	0.00e+00	848.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	51.53	2.00e-116	411.00
IUUC-Loc-052638	Lepisosteus oculatus	42.49	1.00e-90	325.00
IUUC-Spo-108075	Schizosaccharomyces pombe	42.15	2.00e-91	328.00
IUUC-Smo-108922	Selaginella moellendorffii	58.57	4.00e-152	529.00
IUUC-Tae-125122	Triticum aestivum	92.17	0.00e+00	855.00
IUUC-Tur-126018	Triticum urartu	92.83	0.00e+00	857.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence