iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017255

Ensembl Protein ID

Bra034734.1-P

UniProt Accession

M4F0Y9; M4F0Y9_BRARP

Protein Name

Defective in cullin neddylation protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra034734	Bra034734.1	Bra034734.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	3.70e-81	272.7	56	231
UBD/Alpha-Helix/UBA	2.80e-07	31.5	12	50

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 13   YkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdiYrfafnfakdk 108
             dp++d+i++eg++ +c dl+v+p+di++Lvl+w+++aat+cefs+eef+ gl+alg+dsi klqekl +++selkdeqkf++iY+faf +ak+k
   Q: 56   SNDPYSDMILAEGISVLCSDLQVEPQDIVTLVLSWHMNAATACEFSKEEFFGGLQALGVDSIGKLQEKLSFMRSELKDEQKFHEIYNFAFGWAKEK 151
           5799******************************************************************************************** PP
   S: 109  gqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
           gqksl+ldtai +w+Ll+aere++l+++w++fL+++++k+iskDtW++lLef++++++ lsnYd+egaWP+liDefveyl
   Q: 152  GQKSLALDTAIGMWQLLFAEREWPLVNHWCDFLQDRHNKAISKDTWAQLLEFARTVDPALSNYDAEGAWPYLIDEFVEYL 231
           ******************************************************************************97 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlve.MGFdreealqaLraannnleaAveyLld 40
           + dkl+q+v+ +G +++ alqaL a++++leaA +++++
   Q: 12   NRDKLQQFVAiTGASDKNALQALKASDWQLEAAFDMFYS 50
           569*********************************997 PP

Organism

Brassica rapa

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MILCQHKLSR SNRDKLQQFV AITGASDKNA LQALKASDWQ LEAAFDMFYS QPQPRSNDPY 60
SDMILAEGIS VLCSDLQVEP QDIVTLVLSW HMNAATACEF SKEEFFGGLQ ALGVDSIGKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATCTTGT GCCAGCATAA GTTGAGTAGA AGCAACCGGG ATAAACTTCA GCAGTTCGTG 60
GCTATCACTG GAGCTAGGTA ACTGGATCTA TCTTTACCTT ATCGCTAGTT TACTGTAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006285	Arabidopsis lyrata	85.47	1.00e-115	408.00
IUUC-Csv-025976	Ciona savignyi	41.28	4.00e-35	140.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence