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Tag Content
iUUCD ID IUUC-Mcc-054776
Ensembl Protein ID ENSMMUP00000053308.1
UniProt Accession I0FRT6; I0FRT6_MACMU
Genbank Protein ID AFI34718.1; AFI37162.1
Protein Name Mitogen-activated protein kinase kinase kinase 5
Genbank Nucleotide ID JSUE03032149; JV047091
Gene Name MAP3K5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000016376.3 ENSMMUT00000057151.1 ENSMMUP00000053308.1
ENSMMUG00000016376.3 ENSMMUT00000022996.3 ENSMMUP00000021508.3
ENSMMUG00000016376.3 ENSMMUT00000022994.3 ENSMMUP00000021506.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 99.27 0.00e+00 2617.00 IUUC-Hsa-046906
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Macaca mulatta
Protein Sequence
(Fasta)
MSTEAGEGIT FSVPPFAPSG FCTIPEGGIC RRGGAAAVGE SEEHQLPPPP PGSFWNVESA 60
AAPGIGCPAA TSASSATRGR GSSVGGGSRR TTVAYVINEA SQGQLVVAES EALQSLREAC 120
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Protein Fasta Sequence



>IUUC-Mcc-054776|ULD,UBQ_Other|Macaca mulatta
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Nucleotide Sequence
(Fasta)
GCTGGCCAGG CGGTGCGGCT GGGCGGGGGA CGCCGCCGCC GTTGCTGCCC GGCCCGGAGA 60
GATGAGCACG GAGGCGGGCG AGGGCATCAC TTTCTCCGTG CCACCCTTCG CCCCCTCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mcc-054776|ULD,UBQ_Other|Macaca mulatta
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Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

KEGG mcc:711382
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002318 Ailuropoda melanoleuca 96.96 0.00e+00 2362.00
IUUC-Apl-003713 Anas platyrhynchos 89.16 0.00e+00 2076.00
IUUC-Aca-005331 Anolis carolinensis 87.87 0.00e+00 2092.00
IUUC-Ame-011158 Astyanax mexicanus 74.14 0.00e+00 1854.00
IUUC-Bta-012770 Bos taurus 95.12 0.00e+00 2468.00
IUUC-Cja-019656 Callithrix jacchus 98.54 0.00e+00 2569.00
IUUC-Cfa-020488 Canis familiaris 96.14 0.00e+00 2462.00
IUUC-Cpo-022516 Cavia porcellus 94.72 0.00e+00 2334.00
IUUC-Csa-023104 Chlorocebus sabaeus 99.92 0.00e+00 2365.00
IUUC-Cho-024379 Choloepus hoffmanni 90.25 0.00e+00 1236.00
IUUC-Dre-028836 Danio rerio 75.50 0.00e+00 1888.00
IUUC-Dno-029842 Dasypus novemcinctus 94.46 0.00e+00 2212.00
IUUC-Dor-030990 Dipodomys ordii 95.50 0.00e+00 1939.00
IUUC-Ete-032693 Echinops telfairi 85.19 0.00e+00 1999.00
IUUC-Eca-033337 Equus caballus 95.77 0.00e+00 2325.00
IUUC-Eeu-034602 Erinaceus europaeus 80.35 0.00e+00 2063.00
IUUC-Fca-035954 Felis catus 96.38 0.00e+00 1937.00
IUUC-Fal-037358 Ficedula albicollis 88.65 0.00e+00 2106.00
IUUC-Gmo-038836 Gadus morhua 78.62 0.00e+00 1766.00
IUUC-Gga-040443 Gallus gallus 86.65 0.00e+00 2237.00
IUUC-Gac-041634 Gasterosteus aculeatus 75.13 0.00e+00 1942.00
IUUC-Ggo-045263 Gorilla gorilla 97.31 0.00e+00 2511.00
IUUC-Hsa-046906 Homo sapiens 99.27 0.00e+00 2592.00
IUUC-Itr-048449 Ictidomys tridecemlineatus 95.66 0.00e+00 1105.00
IUUC-Lch-050213 Latimeria chalumnae 78.61 0.00e+00 1808.00
IUUC-Loc-051829 Lepisosteus oculatus 72.01 0.00e+00 1879.00
IUUC-Laf-053538 Loxodonta africana 95.34 0.00e+00 2499.00
IUUC-Mga-059636 Meleagris gallopavo 88.61 0.00e+00 2135.00
IUUC-Mmr-061323 Microcebus murinus 96.95 0.00e+00 2492.00
IUUC-Mdo-062146 Monodelphis domestica 91.01 0.00e+00 2338.00
IUUC-Mmu-064022 Mus musculus 94.27 0.00e+00 2437.00
IUUC-Mpu-066531 Mustela putorius furo 93.18 0.00e+00 2476.00
IUUC-Mlu-068181 Myotis lucifugus 90.90 0.00e+00 2401.00
IUUC-Nle-069758 Nomascus leucogenys 99.43 0.00e+00 2357.00
IUUC-Opr-070531 Ochotona princeps 88.25 0.00e+00 1472.00
IUUC-Ont-072014 Oreochromis niloticus 77.57 0.00e+00 1913.00
IUUC-Oan-073169 Ornithorhynchus anatinus 93.40 0.00e+00 2245.00
IUUC-Ocu-074050 Oryctolagus cuniculus 92.57 0.00e+00 2172.00
IUUC-Ola-086941 Oryzias latipes 80.34 0.00e+00 1555.00
IUUC-Oga-088796 Otolemur garnettii 96.00 0.00e+00 2477.00
IUUC-Oar-090445 Ovis aries 96.81 0.00e+00 2302.00
IUUC-Ptr-090846 Pan troglodytes 98.98 0.00e+00 2607.00
IUUC-Pan-091986 Papio anubis 99.93 0.00e+00 2633.00
IUUC-Psi-093805 Pelodiscus sinensis 89.01 0.00e+00 2237.00
IUUC-Pfo-097301 Poecilia formosa 73.99 0.00e+00 1932.00
IUUC-Pab-097662 Pongo abelii 99.25 0.00e+00 2511.00
IUUC-Pca-100755 Procavia capensis 95.16 0.00e+00 728.00
IUUC-Pva-102280 Pteropus vampyrus 86.67 0.00e+00 2266.00
IUUC-Rno-105547 Rattus norvegicus 93.26 0.00e+00 2427.00
IUUC-Sha-106859 Sarcophilus harrisii 90.90 0.00e+00 2288.00
IUUC-Sar-113714 Sorex araneus 84.22 0.00e+00 1946.00
IUUC-Tgu-117116 Taeniopygia guttata 87.39 0.00e+00 2176.00
IUUC-Tru-118088 Takifugu rubripes 74.96 0.00e+00 1953.00
IUUC-Tsy-119616 Tarsius syrichta 91.79 0.00e+00 2013.00
IUUC-Tni-120284 Tetraodon nigroviridis 75.54 0.00e+00 1904.00
IUUC-Tbe-127900 Tupaia belangeri 95.12 0.00e+00 852.00
IUUC-Ttr-128294 Tursiops truncatus 85.31 0.00e+00 2147.00
IUUC-Vpa-130470 Vicugna pacos 87.52 0.00e+00 2068.00
IUUC-Xtr-132396 Xenopus tropicalis 75.67 0.00e+00 1979.00
Created Date 25-Jun-2017

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