iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008258

Ensembl Protein ID

CADACLAP00008825

UniProt Accession

A1CMT0; A1CMT0_ASPCL

Genbank Protein ID

EAW08867.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

DS027058

Gene Name

ACLA_098090

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00009049	CADACLAT00009049	CADACLAP00008825

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-57	194.1	110	564
ULD/UDP/UBQ/UBQ_Other	1.40e-09	36.7	11	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp.............kepkgellkslqklfeelwkskkkavsprellkalkkea 81
           Gl+NlgNtCY+NS+LQ+L ++pel++ ll+ ++ +   +++              + + ++++sl++lf+++ +++++ + p  +l+al+++ 
   Q: 110  GLQNLGNTCYLNSTLQTLRSVPELQQELLR-YRPSAGSSASsrlsdlsslglggLGASMDIVSSLRDLFKQM-SETQEGFPPLLFLNALRSVF 200
           9*****************************.3333333333345566666666666777*************.99999*************** PP
   S: 82   eefs.......gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikc.....lecdnv 162
           ++f        gy+qqDa+E +++++ ql+++l                     ++ e +   + s+ ++ + g+++s + c     +e +++
   Q: 201  PQFAqkdrnghGYAQQDAEEAWSQIVTQLRSKLMI-------------------KEGEADSAAEVSFADKYLAGRFESVTECddpaaKEAGEQ 274
           ***999***************************11...................12356778899****************955444333333 PP
   S: 163  s.sreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
             ++ + f++l +++ ++++     l+d + +   ee++e+     +++ +++   +k+ ++ +lP++L++h+ Rf +++e++++ ki +kv+
   Q: 275  PtESSDIFYKLDCHIGKETN----HLHDGILAG-LEEKIEK----RSPTLDRDAVYTKRSRIARLPKYLTVHFVRFFWKRETQKKAKIMRKVT 358
           33778889999999999986....577766333.3567774....7899999999************************************** PP
   S: 255  fpleLdlspfcts...........................................................peekqke.............. 274
           fp eLd+  fct+                                                           +     e              
   Q: 359  FPAELDVVDFCTEelkkqlvpirdkvrdirkeevdverarkrqkaahqreeelkraaesdaslepmqkkqatE-----Ekkeatkggekdgdt 446
           *************777777777777777777777777776666666666666666666666666655555550.....055555666666666 PP
   S: 275  ...........................................kkkYeLiavvvHsG.slssGHYvayvkn.......ekgkWllfdDskVte 316
                                                      +  YeL +v+ H+G s++sGHY+ayvk+       ++gkW+ f+D+kVte
   Q: 447  amtdvfktdadyeaeknasilvakkelsalvspeiaadtgsnkSGLYELRGVITHQGaSADSGHYTAYVKKqpnskgeDDGKWWWFNDEKVTE 539
           6666666666666666666666666666666666667777666****************************88777766888*********** PP
   S: 317  vkeeevleetg....staYvlfYkr 337
           v+ e++++  g    ++a +l+Y+ 
   Q: 540  VEGEKIETLAGggesHSALILLYRA 564
           ********8889***********85 PP

ULD/UDP/UBQ/UBQ_Other

   S: 9    dgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekksg 75
           +g++++++++p+++  +LK ++++++g+ pe+q++++kG  L+d  +L+++++k g+t++++ + sg
   Q: 11   QGKRHEVELDPAANGETLKYQMYSLTGVEPERQKILVKGGQLKDEAPLSSLNAKAGQTFMMMGTPSG 77
           7899**********************************************************99876 PP

Organism

Aspergillus clavatus

Protein Sequence
(Fasta)

MATIPIIVKH QGKRHEVELD PAANGETLKY QMYSLTGVEP ERQKILVKGG QLKDEAPLSS 60
LNAKAGQTFM MMGTPSGGQA AVERPKEQVK FLEDMTEAEA AGIEGATPAG LQNLGNTCYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAACCA TACCAAGTAT GAAAACCTGC TCTCTTGAAC CGTCTTCTTG ACTTTCTGAA 60
GCTCCTACTG ATGTCAGGTC CTTAGTTATC GTGAAGCACC AGGGCAAACG TCACGAAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00240--ubiquitin
PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005838--C:proteasome regulatory particle
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

act:ACLA_098090

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	28.61	3.00e-30	124.00
IUUC-Aml-002053	Ailuropoda melanoleuca	37.03	3.00e-67	247.00
IUUC-Atr-002725	Amborella trichopoda	34.31	4.00e-76	276.00
IUUC-Apl-004031	Anas platyrhynchos	37.72	5.00e-66	243.00
IUUC-Aca-004361	Anolis carolinensis	35.93	3.00e-84	303.00
IUUC-Aly-006176	Arabidopsis lyrata	35.70	5.00e-83	299.00
IUUC-Ath-007658	Arabidopsis thaliana	35.41	7.00e-88	316.00
IUUC-Ago-007796	Ashbya gossypii	33.51	9.00e-80	288.00
IUUC-Afl-008732	Aspergillus flavus	84.44	0.00e+00	949.00
IUUC-Afu-008755	Aspergillus fumigatus	89.96	0.00e+00	961.00
IUUC-Ani-009148	Aspergillus nidulans	79.27	0.00e+00	871.00
IUUC-Ang-009878	Aspergillus niger	83.57	0.00e+00	915.00
IUUC-Aor-010239	Aspergillus oryzae	84.27	0.00e+00	946.00
IUUC-Ate-010243	Aspergillus terreus	83.22	0.00e+00	909.00
IUUC-Ame-011327	Astyanax mexicanus	30.59	1.00e-17	82.80
IUUC-Bgr-012231	Blumeria graminis	62.74	0.00e+00	711.00
IUUC-Bta-012553	Bos taurus	37.20	2.00e-68	251.00
IUUC-Bci-013606	Botrytis cinerea	64.54	0.00e+00	713.00
IUUC-Bdi-014567	Brachypodium distachyon	37.34	9.00e-80	288.00
IUUC-Bol-015565	Brassica oleracea	38.01	2.00e-90	324.00
IUUC-Bra-017297	Brassica rapa	37.81	8.00e-89	318.00
IUUC-Cel-018140	Caenorhabditis elegans	31.04	1.00e-63	235.00
IUUC-Cja-019516	Callithrix jacchus	37.41	4.00e-67	246.00
IUUC-Cfa-020808	Canis familiaris	37.68	1.00e-69	255.00
IUUC-Cpo-021688	Cavia porcellus	37.65	3.00e-67	247.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	33.50	3.00e-48	184.00
IUUC-Csa-023429	Chlorocebus sabaeus	36.56	6.00e-66	243.00
IUUC-Cho-024347	Choloepus hoffmanni	37.44	4.00e-68	250.00
IUUC-Cin-025198	Ciona intestinalis	36.53	1.00e-53	202.00
IUUC-Csv-026007	Ciona savignyi	36.15	4.00e-59	220.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	59.62	2.00e-175	606.00
IUUC-Cne-026963	Cryptococcus neoformans	35.29	5.00e-81	293.00
IUUC-Cme-027240	Cyanidioschyzon merolae	36.34	9.00e-48	182.00
IUUC-Dre-027647	Danio rerio	36.36	7.00e-84	302.00
IUUC-Dno-029967	Dasypus novemcinctus	37.35	5.00e-66	243.00
IUUC-Dor-030886	Dipodomys ordii	32.69	1.00e-43	169.00
IUUC-Dse-031466	Dothistroma septosporum	54.30	1.00e-158	551.00
IUUC-Dme-032079	Drosophila melanogaster	37.27	9.00e-64	235.00
IUUC-Ete-032351	Echinops telfairi	35.61	2.00e-61	228.00
IUUC-Eca-033461	Equus caballus	37.20	4.00e-73	266.00
IUUC-Eeu-035220	Erinaceus europaeus	32.84	5.00e-40	157.00
IUUC-Fca-036210	Felis catus	37.44	2.00e-69	254.00
IUUC-Fal-037528	Ficedula albicollis	37.72	6.00e-65	239.00
IUUC-Fox-037805	Fusarium oxysporum	60.86	0.00e+00	677.00
IUUC-Fso-038177	Fusarium solani	60.34	0.00e+00	660.00
IUUC-Gmo-038953	Gadus morhua	34.41	9.00e-70	255.00
IUUC-Ggr-039972	Gaeumannomyces graminis	59.10	0.00e+00	637.00
IUUC-Gga-040462	Gallus gallus	37.22	2.00e-64	238.00
IUUC-Gac-041312	Gasterosteus aculeatus	35.66	3.00e-79	286.00
IUUC-Gma-042648	Glycine max	37.60	7.00e-79	286.00
IUUC-Ggo-045458	Gorilla gorilla	32.56	1.00e-42	166.00
IUUC-Hsa-045706	Homo sapiens	36.79	2.00e-66	244.00
IUUC-Hvu-047821	Hordeum vulgare	41.08	9.00e-39	151.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	36.02	2.00e-68	251.00
IUUC-Lch-050464	Latimeria chalumnae	35.61	2.00e-81	294.00
IUUC-Lpe-051419	Leersia perrieri	37.96	8.00e-85	305.00
IUUC-Loc-052732	Lepisosteus oculatus	37.44	2.00e-70	258.00
IUUC-Lma-053177	Leptosphaeria maculans	64.71	0.00e+00	687.00
IUUC-Laf-053822	Loxodonta africana	37.20	6.00e-69	253.00
IUUC-Mcc-055893	Macaca mulatta	36.79	2.00e-66	244.00
IUUC-Meu-056307	Macropus eugenii	36.29	1.00e-61	228.00
IUUC-Mor-057171	Magnaporthe oryzae	57.79	0.00e+00	639.00
IUUC-Mpo-057415	Magnaporthe poae	58.03	0.00e+00	645.00
IUUC-Mtr-057901	Medicago truncatula	36.79	6.00e-85	306.00
IUUC-Mla-058897	Melampsora laricipopulina	37.48	6.00e-94	336.00
IUUC-Mga-060016	Meleagris gallopavo	36.23	9.00e-65	239.00
IUUC-Mvi-060562	Microbotryum violaceum	39.36	2.00e-93	334.00
IUUC-Mmr-060624	Microcebus murinus	37.68	6.00e-73	266.00
IUUC-Mdo-061809	Monodelphis domestica	37.41	2.00e-66	244.00
IUUC-Mmu-063869	Mus musculus	38.08	4.00e-67	246.00
IUUC-Mac-064876	Musa acuminata	39.62	7.00e-64	236.00
IUUC-Mpu-066480	Mustela putorius furo	37.91	4.00e-70	256.00
IUUC-Mlu-067866	Myotis lucifugus	37.20	2.00e-69	254.00
IUUC-Nfi-068393	Neosartorya fischeri	90.32	0.00e+00	988.00
IUUC-Ncr-068815	Neurospora crassa	59.76	0.00e+00	638.00
IUUC-Nle-070121	Nomascus leucogenys	40.85	1.00e-39	154.00
IUUC-Opr-070712	Ochotona princeps	33.20	1.00e-31	129.00
IUUC-Ont-071544	Oreochromis niloticus	39.53	9.00e-68	249.00
IUUC-Oan-073635	Ornithorhynchus anatinus	36.26	3.00e-52	197.00
IUUC-Ocu-074926	Oryctolagus cuniculus	37.68	1.00e-66	245.00
IUUC-Oba-075633	Oryza barthii	40.76	1.00e-71	261.00
IUUC-Obr-076423	Oryza brachyantha	44.20	6.00e-76	276.00
IUUC-Ogl-077913	Oryza glaberrima	37.04	2.00e-79	288.00
IUUC-Ogu-078435	Oryza glumaepatula	40.76	1.00e-71	261.00
IUUC-Oin-080072	Oryza indica	40.76	2.00e-71	261.00
IUUC-Olo-080535	Oryza longistaminata	32.31	2.00e-60	224.00
IUUC-Ome-081309	Oryza meridionalis	40.76	1.00e-71	261.00
IUUC-Oni-083113	Oryza nivara	40.76	1.00e-71	261.00
IUUC-Opu-083168	Oryza punctata	39.49	1.00e-66	244.00
IUUC-Oru-084253	Oryza rufipogon	40.76	1.00e-71	261.00
IUUC-Osa-085554	Oryza sativa	37.23	3.00e-79	287.00
IUUC-Ola-086998	Oryzias latipes	39.31	7.00e-68	249.00
IUUC-Olu-087818	Ostreococcus lucimarinus	32.46	2.00e-59	221.00
IUUC-Oga-088571	Otolemur garnettii	37.53	2.00e-68	251.00
IUUC-Oar-089526	Ovis aries	37.41	2.00e-68	251.00
IUUC-Ptr-091433	Pan troglodytes	36.79	2.00e-66	244.00
IUUC-Pan-091966	Papio anubis	36.56	6.00e-66	243.00
IUUC-Psi-093458	Pelodiscus sinensis	34.61	7.00e-79	286.00
IUUC-Pma-094343	Petromyzon marinus	35.64	8.00e-42	162.00
IUUC-Pno-095109	Phaeosphaeria nodorum	64.54	0.00e+00	704.00
IUUC-Ppa-095756	Physcomitrella patens	38.02	6.00e-92	329.00
IUUC-Pfo-096514	Poecilia formosa	39.31	1.00e-67	248.00
IUUC-Pab-098477	Pongo abelii	33.50	2.00e-51	194.00
IUUC-Pop-099221	Populus trichocarpa	35.97	5.00e-82	296.00
IUUC-Pca-100791	Procavia capensis	29.18	2.00e-28	118.00
IUUC-Ppe-101812	Prunus persica	35.69	4.00e-84	303.00
IUUC-Pva-102462	Pteropus vampyrus	35.67	2.00e-55	207.00
IUUC-Pgr-103623	Puccinia graminis	42.34	1.00e-75	275.00
IUUC-Ptt-103767	Puccinia triticina	36.55	2.00e-87	314.00
IUUC-Pte-104109	Pyrenophora teres	66.72	0.00e+00	720.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	65.41	0.00e+00	702.00
IUUC-Rno-105351	Rattus norvegicus	36.61	2.00e-64	238.00
IUUC-Sce-106168	Saccharomyces cerevisiae	33.27	1.00e-76	278.00
IUUC-Sha-107491	Sarcophilus harrisii	38.18	1.00e-67	248.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	38.15	2.00e-97	347.00
IUUC-Spo-108174	Schizosaccharomyces pombe	40.43	3.00e-107	380.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	67.18	0.00e+00	712.00
IUUC-Smo-108805	Selaginella moellendorffii	41.75	3.00e-79	287.00
IUUC-Sit-110361	Setaria italica	44.20	1.00e-78	285.00
IUUC-Sly-110965	Solanum lycopersicum	37.25	3.00e-84	303.00
IUUC-Sar-113355	Sorex araneus	37.54	2.00e-54	204.00
IUUC-Sbi-114778	Sorghum bicolor	44.20	2.00e-76	278.00
IUUC-Sre-115011	Sporisorium reilianum	44.97	3.00e-83	300.00
IUUC-Ssc-116273	Sus scrofa	37.41	2.00e-66	244.00
IUUC-Tgu-117063	Taeniopygia guttata	37.47	5.00e-65	239.00
IUUC-Tru-118381	Takifugu rubripes	37.68	2.00e-68	251.00
IUUC-Tsy-119076	Tarsius syrichta	45.12	3.00e-16	77.80
IUUC-Tni-119941	Tetraodon nigroviridis	38.97	4.00e-69	253.00
IUUC-Tca-121246	Theobroma cacao	36.36	2.00e-84	304.00
IUUC-Tre-121969	Trichoderma reesei	57.98	2.00e-175	606.00
IUUC-Tvi-122543	Trichoderma virens	57.44	1.00e-180	624.00
IUUC-Tae-125744	Triticum aestivum	38.98	5.00e-88	316.00
IUUC-Tur-126128	Triticum urartu	41.83	2.00e-21	95.50
IUUC-Tbe-128030	Tupaia belangeri	36.51	2.00e-41	162.00
IUUC-Ttr-128701	Tursiops truncatus	36.90	1.00e-50	191.00
IUUC-Uma-129657	Ustilago maydis	40.72	2.00e-101	361.00
IUUC-Vda-129723	Verticillium dahliae	58.53	0.00e+00	650.00
IUUC-Vpa-130284	Vicugna pacos	33.17	2.00e-25	108.00
IUUC-Vvi-131037	Vitis vinifera	37.25	7.00e-88	315.00
IUUC-Xtr-132235	Xenopus tropicalis	39.39	2.00e-71	261.00
IUUC-Xma-133840	Xiphophorus maculatus	39.31	1.00e-67	248.00
IUUC-Yli-134453	Yarrowia lipolytica	42.91	6.00e-113	399.00
IUUC-Zma-135791	Zea mays	37.32	2.00e-82	297.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence