iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048833

Ensembl Protein ID

ENSSTOP00000018506.1

UniProt Accession

I3N2B0; I3N2B0_ICTTR

Genbank Protein ID

ENSSTOP00000018506

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01072138

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000019535.1	ENSSTOT00000025179.1	ENSSTOP00000018506.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.40e-13	47.9	497	546

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 497  TALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 546
           69***********************..9*********..7************97 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MWKASAGHTV ALTQDTGAAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE 60
NVSQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAGG CCTCTGCAGG CCACACCGTG GCCCTCACGC AGGACACCGG GGCAGCTGAC 60
GACTGGGAGA CCGACCCTGA CTTTGTGGTG GGTTCAGCCT GCCGCGCTGC CCTGTCCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	87.27	0.00e+00	882.00
IUUC-Apl-003745	Anas platyrhynchos	81.01	0.00e+00	747.00
IUUC-Aca-004438	Anolis carolinensis	77.76	0.00e+00	791.00
IUUC-Ame-011504	Astyanax mexicanus	55.12	1.00e-95	343.00
IUUC-Bgr-012041	Blumeria graminis	60.71	2.00e-16	80.90
IUUC-Bta-013563	Bos taurus	85.43	0.00e+00	841.00
IUUC-Cfa-020718	Canis familiaris	84.06	0.00e+00	871.00
IUUC-Cpo-022303	Cavia porcellus	85.43	0.00e+00	912.00
IUUC-Csa-023431	Chlorocebus sabaeus	87.61	0.00e+00	884.00
IUUC-Cin-025677	Ciona intestinalis	59.67	1.00e-116	413.00
IUUC-Csv-026140	Ciona savignyi	61.33	1.00e-105	376.00
IUUC-Dre-028012	Danio rerio	74.30	7.00e-149	520.00
IUUC-Dno-029332	Dasypus novemcinctus	80.51	0.00e+00	753.00
IUUC-Dme-031931	Drosophila melanogaster	63.48	8.00e-75	274.00
IUUC-Eca-033801	Equus caballus	87.80	0.00e+00	874.00
IUUC-Fca-035633	Felis catus	86.09	0.00e+00	732.00
IUUC-Fal-036775	Ficedula albicollis	80.51	0.00e+00	747.00
IUUC-Gmo-038507	Gadus morhua	61.64	2.00e-21	97.10
IUUC-Gga-040568	Gallus gallus	81.56	0.00e+00	775.00
IUUC-Gac-042253	Gasterosteus aculeatus	55.86	2.00e-115	409.00
IUUC-Hsa-046818	Homo sapiens	87.98	0.00e+00	885.00
IUUC-Lch-050199	Latimeria chalumnae	68.06	4.00e-136	478.00
IUUC-Loc-052855	Lepisosteus oculatus	75.28	2.00e-153	535.00
IUUC-Laf-053866	Loxodonta africana	86.08	0.00e+00	884.00
IUUC-Mcc-055515	Macaca mulatta	87.98	0.00e+00	885.00
IUUC-Mga-059791	Meleagris gallopavo	77.60	0.00e+00	771.00
IUUC-Mmr-061147	Microcebus murinus	87.84	0.00e+00	839.00
IUUC-Mdo-062660	Monodelphis domestica	60.29	4.00e-169	588.00
IUUC-Mmu-064023	Mus musculus	87.25	0.00e+00	868.00
IUUC-Mpu-065867	Mustela putorius furo	84.55	2.00e-174	604.00
IUUC-Mlu-067704	Myotis lucifugus	82.18	0.00e+00	777.00
IUUC-Ont-071873	Oreochromis niloticus	79.27	2.00e-163	568.00
IUUC-Oan-073528	Ornithorhynchus anatinus	79.05	4.00e-152	530.00
IUUC-Oga-088028	Otolemur garnettii	86.89	0.00e+00	871.00
IUUC-Oar-090203	Ovis aries	85.63	0.00e+00	768.00
IUUC-Pan-092594	Papio anubis	85.09	0.00e+00	841.00
IUUC-Psi-093389	Pelodiscus sinensis	79.26	0.00e+00	773.00
IUUC-Pma-094161	Petromyzon marinus	46.28	1.00e-80	293.00
IUUC-Pno-095096	Phaeosphaeria nodorum	60.00	2.00e-14	74.30
IUUC-Pfo-097391	Poecilia formosa	55.03	1.00e-111	396.00
IUUC-Pab-097913	Pongo abelii	82.12	0.00e+00	797.00
IUUC-Rno-105489	Rattus norvegicus	87.61	0.00e+00	846.00
IUUC-Sce-106228	Saccharomyces cerevisiae	50.00	6.00e-07	48.90
IUUC-Sha-107308	Sarcophilus harrisii	68.29	3.00e-179	621.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	7.00e-15	75.50
IUUC-Tgu-117049	Taeniopygia guttata	75.73	0.00e+00	695.00
IUUC-Tru-118718	Takifugu rubripes	75.70	1.00e-156	545.00
IUUC-Tni-120535	Tetraodon nigroviridis	72.35	2.00e-145	508.00
IUUC-Vda-129766	Verticillium dahliae	60.00	4.00e-14	73.20
IUUC-Xtr-131797	Xenopus tropicalis	72.91	2.00e-148	519.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence