iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010815.1	ENSSHAT00000012740.1	ENSSHAP00000012636.1
ENSSHAG00000010815.1	ENSSHAT00000012741.1	ENSSHAP00000012637.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-11	43.1	506	557

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++lydy+++ +de ++   d+++ i  e  degW++g  + +g+ GlfP+n+v+ l
   Q: 506  IALYDYQGEGNDEISFDPDDTITDI--EMIDEGWWRG--HCRGRFGLFPANYVQLL 557
           79**********************9..9*********..9*************976 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MWKSVVGHDV SVSVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRKE HINIHQLRNK 60
VSEEHDVLKK KEMEAGPKAS HGYGGKFGVE RDRMDKSALG HEYVADVEKH SSQTDAAKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAATGAA AATGATCTGA AACAGGAACT TACTAAGGGG TAAGCACTTT CTTACTCCGG 60
ATCAGCAGCA GCAGCAGTCA GAGAAGGAGC AGAATCTCCA GGAAGACTCA GATTGTGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

KEGG

shr:100925593

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011504	Astyanax mexicanus	53.99	4.00e-142	498.00
IUUC-Bta-012591	Bos taurus	62.30	2.00e-132	465.00
IUUC-Cja-019982	Callithrix jacchus	92.63	8.00e-116	410.00
IUUC-Cin-025677	Ciona intestinalis	52.57	6.00e-95	341.00
IUUC-Csv-026140	Ciona savignyi	58.33	3.00e-89	322.00
IUUC-Dre-028127	Danio rerio	64.43	2.00e-135	476.00
IUUC-Dor-030437	Dipodomys ordii	54.21	2.00e-95	342.00
IUUC-Dme-031931	Drosophila melanogaster	57.83	2.00e-70	259.00
IUUC-Ete-033160	Echinops telfairi	56.32	7.00e-102	363.00
IUUC-Eeu-035032	Erinaceus europaeus	51.95	7.00e-90	323.00
IUUC-Fca-035999	Felis catus	61.01	4.00e-123	434.00
IUUC-Gac-042253	Gasterosteus aculeatus	65.33	2.00e-132	465.00
IUUC-Ggo-044505	Gorilla gorilla	59.66	1.00e-155	542.00
IUUC-Lch-050221	Latimeria chalumnae	68.42	4.00e-138	484.00
IUUC-Loc-052855	Lepisosteus oculatus	64.58	9.00e-126	443.00
IUUC-Mdo-062515	Monodelphis domestica	68.46	5.00e-164	570.00
IUUC-Mmu-064341	Mus musculus	61.77	4.00e-118	417.00
IUUC-Nle-069436	Nomascus leucogenys	63.22	4.00e-134	471.00
IUUC-Opr-070288	Ochotona princeps	54.56	5.00e-128	451.00
IUUC-Ont-071712	Oreochromis niloticus	73.75	3.00e-131	461.00
IUUC-Ocu-074686	Oryctolagus cuniculus	59.24	8.00e-150	523.00
IUUC-Ola-086894	Oryzias latipes	60.37	4.00e-101	361.00
IUUC-Oar-089686	Ovis aries	61.83	2.00e-118	419.00
IUUC-Ptr-090461	Pan troglodytes	63.22	2.00e-134	472.00
IUUC-Psi-093785	Pelodiscus sinensis	52.88	3.00e-157	548.00
IUUC-Pma-094161	Petromyzon marinus	48.60	7.00e-88	317.00
IUUC-Pfo-097391	Poecilia formosa	70.72	6.00e-139	487.00
IUUC-Pca-100668	Procavia capensis	58.22	1.00e-114	406.00
IUUC-Pva-102767	Pteropus vampyrus	55.47	2.00e-97	349.00
IUUC-Sar-113338	Sorex araneus	53.51	1.00e-136	479.00
IUUC-Ssc-116027	Sus scrofa	60.96	5.00e-166	577.00
IUUC-Tru-118637	Takifugu rubripes	64.37	2.00e-129	456.00
IUUC-Tni-119931	Tetraodon nigroviridis	63.12	4.00e-115	408.00
IUUC-Xtr-131797	Xenopus tropicalis	48.91	1.00e-140	493.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence