iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000011018.3	ENSMMUT00000067288.1	ENSMMUP00000049301.1
ENSMMUG00000011018.3	ENSMMUT00000015400.3	ENSMMUP00000014425.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.82	0.00e+00	933.00	IUUC-Hsa-045784
E3 activity/RING/RING	34.10	2.00e-28	121.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKN SEPAQQPHRP LDPLTMHSTY DRAGAVPRTP LAGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCCGCG CGCGCCTGCG CAGGACGCAA CAGCGCGCAC GGGCGGCGGG AGGAGCGCGC 60
GCGGGTGCTA ATTGGCTCGG GTGGCGGCCC CGCCCGCGAG TGGTGGGCGG TCACGTGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0016874--F:ligase activity
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	91.75	0.00e+00	886.00
IUUC-Apl-003765	Anas platyrhynchos	82.18	0.00e+00	812.00
IUUC-Ame-010763	Astyanax mexicanus	59.78	2.00e-146	512.00
IUUC-Bta-012369	Bos taurus	93.76	0.00e+00	906.00
IUUC-Cja-019450	Callithrix jacchus	96.47	0.00e+00	927.00
IUUC-Cfa-020933	Canis familiaris	93.20	0.00e+00	897.00
IUUC-Cpo-022112	Cavia porcellus	91.98	0.00e+00	865.00
IUUC-Csa-023913	Chlorocebus sabaeus	87.94	0.00e+00	770.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.72	3.00e-34	139.00
IUUC-Dre-027609	Danio rerio	59.01	8.00e-142	497.00
IUUC-Dno-029664	Dasypus novemcinctus	74.38	1.00e-153	536.00
IUUC-Ete-032988	Echinops telfairi	92.74	6.00e-173	600.00
IUUC-Eca-034430	Equus caballus	91.37	0.00e+00	868.00
IUUC-Fca-035968	Felis catus	97.26	2.00e-168	584.00
IUUC-Fal-037449	Ficedula albicollis	83.53	0.00e+00	800.00
IUUC-Fso-038103	Fusarium solani	34.72	1.00e-26	114.00
IUUC-Gmo-038925	Gadus morhua	60.78	3.00e-139	488.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.48	1.00e-29	124.00
IUUC-Gga-040362	Gallus gallus	85.91	0.00e+00	848.00
IUUC-Gac-042353	Gasterosteus aculeatus	59.05	3.00e-133	468.00
IUUC-Ggo-044810	Gorilla gorilla	96.27	0.00e+00	897.00
IUUC-Hsa-045784	Homo sapiens	98.82	0.00e+00	947.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	90.10	0.00e+00	881.00
IUUC-Lch-049727	Latimeria chalumnae	72.22	2.00e-152	531.00
IUUC-Loc-052354	Lepisosteus oculatus	51.88	1.00e-122	433.00
IUUC-Laf-054261	Loxodonta africana	92.82	0.00e+00	902.00
IUUC-Meu-056468	Macropus eugenii	87.48	0.00e+00	867.00
IUUC-Mpo-057405	Magnaporthe poae	33.06	1.00e-28	121.00
IUUC-Mga-059981	Meleagris gallopavo	88.83	0.00e+00	706.00
IUUC-Mvi-060421	Microbotryum violaceum	29.22	2.00e-27	117.00
IUUC-Mmr-061181	Microcebus murinus	92.03	0.00e+00	867.00
IUUC-Mdo-062345	Monodelphis domestica	87.28	0.00e+00	869.00
IUUC-Mmu-063197	Mus musculus	86.60	0.00e+00	850.00
IUUC-Mpu-066275	Mustela putorius furo	91.83	0.00e+00	896.00
IUUC-Mlu-067194	Myotis lucifugus	93.01	0.00e+00	904.00
IUUC-Ncr-068929	Neurospora crassa	27.70	2.00e-27	117.00
IUUC-Ont-072227	Oreochromis niloticus	59.05	7.00e-139	487.00
IUUC-Obr-076179	Oryza brachyantha	32.58	2.00e-20	95.10
IUUC-Ola-086865	Oryzias latipes	58.78	4.00e-138	484.00
IUUC-Oga-088945	Otolemur garnettii	96.09	0.00e+00	931.00
IUUC-Oar-089412	Ovis aries	91.21	0.00e+00	866.00
IUUC-Ptr-091550	Pan troglodytes	86.84	0.00e+00	649.00
IUUC-Pan-092183	Papio anubis	99.80	0.00e+00	950.00
IUUC-Psi-093003	Pelodiscus sinensis	83.95	0.00e+00	829.00
IUUC-Pfo-096704	Poecilia formosa	59.10	1.00e-141	496.00
IUUC-Pab-097923	Pongo abelii	99.48	0.00e+00	780.00
IUUC-Pca-100249	Procavia capensis	77.41	3.00e-143	501.00
IUUC-Pva-102562	Pteropus vampyrus	89.09	0.00e+00	833.00
IUUC-Rno-105762	Rattus norvegicus	87.57	0.00e+00	853.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	9.00e-29	122.00
IUUC-Sha-107253	Sarcophilus harrisii	86.50	0.00e+00	860.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	30.42	6.00e-29	122.00
IUUC-Sar-113149	Sorex araneus	85.45	1.00e-126	446.00
IUUC-Ssc-115241	Sus scrofa	93.76	0.00e+00	911.00
IUUC-Tgu-116884	Taeniopygia guttata	84.16	0.00e+00	801.00
IUUC-Tru-118031	Takifugu rubripes	59.50	6.00e-145	507.00
IUUC-Tni-119766	Tetraodon nigroviridis	59.46	3.00e-140	491.00
IUUC-Ttr-128556	Tursiops truncatus	84.14	0.00e+00	734.00
IUUC-Xtr-131866	Xenopus tropicalis	76.83	0.00e+00	760.00
IUUC-Xma-133963	Xiphophorus maculatus	59.37	2.00e-135	475.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence