iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059652

UUCD1 version

UUC-MeG-00590

Ensembl Protein ID

ENSMGAP00000013654.2

UniProt Accession

G1NJV3; G1NJV3_MELGA

Protein Name

Uncharacterized protein

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000012950.2	ENSMGAT00000014566.2	ENSMGAP00000013654.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.10e-26	91.0	405	476
E3 adaptor/Cullin RING/DCX/DWD	8.60e-38	126.5	52	88
UBD/Beta-Prp	1.20e-54	185.2	141	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           vp+eflCpI+ elM+dPv++++G++y++++Ie w++++++++P+t+ pl +  l+Pn tl+  i++w+e+++
   Q: 405  VPDEFLCPITRELMKDPVIAADGYSYEKEAIENWISNKRRSSPMTNLPLPSLVLTPNRTLKMAISRWLETQQ 476
           8*******************************************************************9986 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt  v+c++f ++ ++l+s+s Dg   vWD r+g+ 
   Q: 52   GHTYAVHCCCFsPSgHTLASCSTDGATIVWDARDGRM 88
           8***********66699***************99986 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk..........ilvtgseDrtikvw.....dlstgk 85
            + + +fsp +++++tgs  g ++vwd ++  +l   + h+ +vt++++s++             ++++++D+ ikvw     d+  g+
   Q: 141  SLVACAFSPCGNFFVTGSSCGDLTVWDDKM-RCLCNEKAHDLGVTCCDISSHPVsdgehasgyfQMASCGQDNKIKVWfilfaDFLGGE 228
           5556799********************887.888999************98854667899999999************98888777776 PP
   S: 86   cvh..tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...... 166
             +  tl+gh++ vl+++fs +g+ lvsGs d+++ +++++tg  l+ tls+h++ v++ ++ p + ll++Gs D++v +W+l      
   Q: 229  LRYkcTLSGHSAPVLACAFSYDGQMLVSGSVDKYVIIYETNTGNILH-TLSQHTRYVTTCAFAPHSLLLATGSMDKAVHVWQLdnrqpc 316
           55511677***************************************.**********************************9766666 PP
   S: 167  .....ktgkllrt 174
                ++++ +rt
   Q: 317  agnaiESNSKIRT 329
           6666655555555 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MATLIHTLRD HSDDVNCCAF SSSCLATCSL DKSIRIYSLN DFTELPYSPL KGHTYAVHCC 60
CFSPSGHTLA SCSTDGATIV WDARDGRMLA VLEQPTGSPV RVCRFSPESS YLVSGAADGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACAC TAATTCACAC TTTAAGAGAT CATAGTGATG ATGTCAACTG CTGTGCCTTC 60
TCATCGTCGT GCTTGGCTAC TTGTTCCTTG GACAAATCAA TTCGTATTTA CTCCTTAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000476	Aegilops tauschii	50.57	2.00e-19	90.90
IUUC-Aml-001614	Ailuropoda melanoleuca	74.84	0.00e+00	759.00
IUUC-Apl-003529	Anas platyrhynchos	84.28	0.00e+00	845.00
IUUC-Aca-004257	Anolis carolinensis	68.24	0.00e+00	684.00
IUUC-Ame-011357	Astyanax mexicanus	50.10	2.00e-114	405.00
IUUC-Bta-013032	Bos taurus	72.80	0.00e+00	733.00
IUUC-Cja-018743	Callithrix jacchus	73.38	0.00e+00	748.00
IUUC-Cfa-021197	Canis familiaris	74.21	0.00e+00	753.00
IUUC-Cpo-022279	Cavia porcellus	73.38	0.00e+00	741.00
IUUC-Csa-023954	Chlorocebus sabaeus	74.84	0.00e+00	755.00
IUUC-Cho-025083	Choloepus hoffmanni	61.21	5.00e-128	450.00
IUUC-Cin-025786	Ciona intestinalis	37.42	1.00e-85	310.00
IUUC-Dre-028087	Danio rerio	55.51	3.00e-140	491.00
IUUC-Dno-028919	Dasypus novemcinctus	74.00	0.00e+00	745.00
IUUC-Dor-031112	Dipodomys ordii	71.70	0.00e+00	715.00
IUUC-Ete-032405	Echinops telfairi	72.59	9.00e-149	518.00
IUUC-Eca-033254	Equus caballus	72.54	0.00e+00	737.00
IUUC-Eeu-034545	Erinaceus europaeus	69.60	0.00e+00	684.00
IUUC-Fca-035482	Felis catus	75.05	0.00e+00	759.00
IUUC-Fal-036976	Ficedula albicollis	68.38	0.00e+00	636.00
IUUC-Gmo-039213	Gadus morhua	54.53	3.00e-134	471.00
IUUC-Gga-040561	Gallus gallus	93.50	0.00e+00	934.00
IUUC-Gac-041471	Gasterosteus aculeatus	56.24	3.00e-133	468.00
IUUC-Ggo-045503	Gorilla gorilla	74.21	0.00e+00	750.00
IUUC-Hsa-045910	Homo sapiens	74.21	0.00e+00	749.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	71.96	2.00e-163	568.00
IUUC-Loc-052307	Lepisosteus oculatus	57.82	7.00e-169	586.00
IUUC-Laf-053587	Loxodonta africana	72.96	0.00e+00	740.00
IUUC-Mcc-055679	Macaca mulatta	74.63	0.00e+00	753.00
IUUC-Meu-055962	Macropus eugenii	64.36	3.00e-172	597.00
IUUC-Mmr-060943	Microcebus murinus	70.98	0.00e+00	719.00
IUUC-Mdo-062592	Monodelphis domestica	73.07	0.00e+00	745.00
IUUC-Mmu-063577	Mus musculus	69.46	0.00e+00	692.00
IUUC-Mac-064539	Musa acuminata	56.16	2.00e-21	97.40
IUUC-Mpu-066422	Mustela putorius furo	74.00	0.00e+00	756.00
IUUC-Mlu-067250	Myotis lucifugus	72.54	0.00e+00	729.00
IUUC-Nle-069517	Nomascus leucogenys	74.00	0.00e+00	749.00
IUUC-Opr-070776	Ochotona princeps	72.96	0.00e+00	727.00
IUUC-Ont-071821	Oreochromis niloticus	57.11	1.00e-146	512.00
IUUC-Oan-073706	Ornithorhynchus anatinus	74.58	0.00e+00	758.00
IUUC-Ocu-074766	Oryctolagus cuniculus	66.11	0.00e+00	648.00
IUUC-Ola-086531	Oryzias latipes	56.33	1.00e-139	489.00
IUUC-Oga-088388	Otolemur garnettii	72.33	0.00e+00	737.00
IUUC-Oar-089748	Ovis aries	72.80	0.00e+00	737.00
IUUC-Ptr-090616	Pan troglodytes	74.05	0.00e+00	744.00
IUUC-Pan-091769	Papio anubis	73.84	2.00e-152	531.00
IUUC-Psi-093334	Pelodiscus sinensis	77.15	0.00e+00	738.00
IUUC-Pma-094383	Petromyzon marinus	50.29	8.00e-135	473.00
IUUC-Pfo-096801	Poecilia formosa	54.75	5.00e-143	500.00
IUUC-Pab-098139	Pongo abelii	72.82	1.00e-172	598.00
IUUC-Pop-099101	Populus trichocarpa	52.44	1.00e-20	95.10
IUUC-Pca-100523	Procavia capensis	72.47	2.00e-139	488.00
IUUC-Pva-102286	Pteropus vampyrus	74.00	0.00e+00	723.00
IUUC-Rno-104831	Rattus norvegicus	70.23	0.00e+00	704.00
IUUC-Sha-107499	Sarcophilus harrisii	74.42	0.00e+00	758.00
IUUC-Sar-113389	Sorex araneus	72.12	0.00e+00	712.00
IUUC-Tgu-116769	Taeniopygia guttata	81.55	0.00e+00	812.00
IUUC-Tru-118774	Takifugu rubripes	53.28	4.00e-137	480.00
IUUC-Tsy-119595	Tarsius syrichta	62.86	4.00e-144	503.00
IUUC-Tni-119850	Tetraodon nigroviridis	55.49	2.00e-141	494.00
IUUC-Tbe-127938	Tupaia belangeri	68.20	3.00e-119	421.00
IUUC-Ttr-128193	Tursiops truncatus	72.94	9.00e-179	619.00
IUUC-Vpa-130275	Vicugna pacos	74.42	0.00e+00	750.00
IUUC-Xtr-131982	Xenopus tropicalis	61.19	1.00e-170	592.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence