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Tag Content
iUUCD ID IUUC-Mpu-066630
Ensembl Protein ID ENSMPUP00000016999.1
UniProt Accession M3Z088; M3Z088_MUSPF
Genbank Protein ID ENSMPUP00000016999
Protein Name Protein kinase C
Genbank Nucleotide ID AEYP01041506
Gene Name PRKCI
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMPUG00000017108.1 ENSMPUT00000017253.1 ENSMPUP00000016999.1
Status Unreviewed
Classification
Family E-Value Score Start End
ULD/UDP/UFD/PB1 8.80e-22 77.1 67 148
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelkn.sevalkYeDedGDlvtlksDedldkavslla.skksllrlliq 82
    +vrvk++y+g+i + +++e++++fe L+++vr++++++n + +++k+ De+GD +t++s+ +l++a++l++ +k+s l ++++
   Q: 67 QVRVKAYYRGDI--MITHFEPSISFEGLCSEVRDMCSFDNeQLFTMKWIDEEGDPCTVSSQLELEEAFRLYElNKDSELLIHVF 148
    69**********..88******************************************************************98 PP
   

Organism Mustela putorius furo
Protein Sequence
(Fasta)
MDRWLRPPSP GMWAFGASEV GGTRAGRRAG PGRREEPRGS GCPGEATLGS APRAEWTGGG 60
SGDHSHQVRV KAYYRGDIMI THFEPSISFE GLCSEVRDMC SFDNEQLFTM KWIDEEGDPC 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mpu-066630|ULD,PB1|Mustela putorius furo
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGATCGAT GGTTGCGCCC GCCCTCCCCC GGAATGTGGG CCTTTGGAGC GAGCGAGGTG 60
GGAGGGACCC GAGCGGGGAG GCGTGCTGGG CCCGGGCGGC GGGAGGAGCC GCGCGGTTCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mpu-066630|ULD,PB1|Mustela putorius furo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR034661--aPKC_iota
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR012233--PKC
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045171--C:intercellular bridge
GO:0015630--C:microtubule cytoskeleton
GO:0005634--C:nucleus
GO:0043220--C:Schmidt-Lanterman incisure
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0005543--F:phospholipid binding
GO:0004697--F:protein kinase C activity
GO:0007015--P:actin filament organization
GO:0045216--P:cell-cell junction organization
GO:0032869--P:cellular response to insulin stimulus
GO:0035089--P:establishment of apical/basal cell polarity
GO:0042462--P:eye photoreceptor cell development
GO:0035556--P:intracellular signal transduction
GO:0034351--P:negative regulation of glial cell apoptotic process
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0018105--P:peptidyl-serine phosphorylation
GO:2000353--P:positive regulation of endothelial cell apoptotic process
GO:0090004--P:positive regulation of establishment of protein localization to plasma membrane
GO:0060252--P:positive regulation of glial cell proliferation
GO:0046326--P:positive regulation of glucose import
GO:0010976--P:positive regulation of neuron projection development
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001764 Ailuropoda melanoleuca 99.62 0.00e+00 1025.00
IUUC-Apl-003711 Anas platyrhynchos 95.92 0.00e+00 1076.00
IUUC-Aca-005142 Anolis carolinensis 94.77 0.00e+00 1095.00
IUUC-Ame-010977 Astyanax mexicanus 88.66 0.00e+00 1003.00
IUUC-Bta-013414 Bos taurus 99.31 0.00e+00 1154.00
IUUC-Bol-015169 Brassica oleracea 35.29 8.00e-51 195.00
IUUC-Cel-018340 Caenorhabditis elegans 56.55 0.00e+00 696.00
IUUC-Cja-019802 Callithrix jacchus 99.47 0.00e+00 1111.00
IUUC-Cfa-021236 Canis familiaris 98.30 0.00e+00 1135.00
IUUC-Cpo-022127 Cavia porcellus 97.35 0.00e+00 1070.00
IUUC-Csa-023332 Chlorocebus sabaeus 99.59 0.00e+00 952.00
IUUC-Cho-025054 Choloepus hoffmanni 66.58 3.00e-119 422.00
IUUC-Cin-025740 Ciona intestinalis 59.33 0.00e+00 699.00
IUUC-Csv-026145 Ciona savignyi 78.57 1.00e-175 609.00
IUUC-Dre-028444 Danio rerio 89.43 0.00e+00 1018.00
IUUC-Dno-029228 Dasypus novemcinctus 100.00 0.00e+00 647.00
IUUC-Dme-031630 Drosophila melanogaster 66.56 0.00e+00 792.00
IUUC-Ete-032633 Echinops telfairi 73.73 0.00e+00 652.00
IUUC-Eca-033572 Equus caballus 99.82 0.00e+00 1117.00
IUUC-Eeu-035110 Erinaceus europaeus 97.95 0.00e+00 1148.00
IUUC-Fca-035559 Felis catus 99.83 0.00e+00 1159.00
IUUC-Fal-036953 Ficedula albicollis 96.62 0.00e+00 1086.00
IUUC-Gmo-039334 Gadus morhua 88.39 0.00e+00 1031.00
IUUC-Gga-040223 Gallus gallus 95.49 0.00e+00 1105.00
IUUC-Gac-042113 Gasterosteus aculeatus 88.73 0.00e+00 1036.00
IUUC-Ggo-044520 Gorilla gorilla 92.29 0.00e+00 1043.00
IUUC-Hsa-046991 Homo sapiens 99.14 0.00e+00 1159.00
IUUC-Lch-050263 Latimeria chalumnae 89.77 0.00e+00 1052.00
IUUC-Loc-052221 Lepisosteus oculatus 89.95 0.00e+00 1020.00
IUUC-Laf-053591 Loxodonta africana 99.14 0.00e+00 1155.00
IUUC-Mcc-055118 Macaca mulatta 96.22 0.00e+00 1124.00
IUUC-Mga-059886 Meleagris gallopavo 95.74 0.00e+00 1074.00
IUUC-Mmr-060926 Microcebus murinus 99.31 0.00e+00 1157.00
IUUC-Mdo-062698 Monodelphis domestica 95.83 0.00e+00 1097.00
IUUC-Mmu-063689 Mus musculus 98.79 0.00e+00 1140.00
IUUC-Mlu-067416 Myotis lucifugus 94.29 0.00e+00 1087.00
IUUC-Nle-069811 Nomascus leucogenys 99.31 0.00e+00 1158.00
IUUC-Opr-070466 Ochotona princeps 86.55 0.00e+00 742.00
IUUC-Ont-072278 Oreochromis niloticus 86.36 0.00e+00 977.00
IUUC-Oan-073651 Ornithorhynchus anatinus 98.62 0.00e+00 744.00
IUUC-Ocu-074383 Oryctolagus cuniculus 99.31 0.00e+00 1156.00
IUUC-Ola-087283 Oryzias latipes 82.85 0.00e+00 784.00
IUUC-Oga-088337 Otolemur garnettii 90.69 0.00e+00 1030.00
IUUC-Oar-089954 Ovis aries 99.47 0.00e+00 1121.00
IUUC-Ptr-091673 Pan troglodytes 99.14 0.00e+00 1159.00
IUUC-Pan-092494 Papio anubis 88.70 0.00e+00 1168.00
IUUC-Psi-094044 Pelodiscus sinensis 96.01 0.00e+00 1105.00
IUUC-Pfo-096661 Poecilia formosa 87.09 0.00e+00 990.00
IUUC-Pab-097659 Pongo abelii 88.55 0.00e+00 1163.00
IUUC-Pca-101107 Procavia capensis 98.73 0.00e+00 795.00
IUUC-Rno-105790 Rattus norvegicus 99.14 0.00e+00 1148.00
IUUC-Sha-106895 Sarcophilus harrisii 97.17 0.00e+00 1075.00
IUUC-Sar-113513 Sorex araneus 99.07 2.00e-176 612.00
IUUC-Ssc-115835 Sus scrofa 99.23 0.00e+00 1027.00
IUUC-Tgu-116874 Taeniopygia guttata 96.17 0.00e+00 1109.00
IUUC-Tru-117823 Takifugu rubripes 88.03 0.00e+00 1010.00
IUUC-Tsy-119154 Tarsius syrichta 99.47 0.00e+00 1116.00
IUUC-Tni-119968 Tetraodon nigroviridis 86.73 0.00e+00 987.00
IUUC-Tbe-127238 Tupaia belangeri 79.39 0.00e+00 736.00
IUUC-Ttr-129208 Tursiops truncatus 99.48 0.00e+00 1154.00
IUUC-Vpa-130363 Vicugna pacos 88.53 0.00e+00 985.00
IUUC-Xtr-132652 Xenopus tropicalis 87.31 0.00e+00 1034.00
Created Date 25-Jun-2017

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