iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004480

Ensembl Protein ID

ENSACAP00000006688.3

UniProt Accession

G1KFT1; G1KFT1_ANOCA

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006771.3	ENSACAT00000006834.3	ENSACAP00000006688.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	47.24	7.00e-124	441.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	40.35	2.00e-106	380.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAEKPPPPQK HDGRVKIGHY VLGDTLGVGT FGKVKIGEHQ LTGHKVAVKI LNRQKIRSLD 60
VVGKIKREIQ NLKLFRHPHI IKLYQVISTP TDFFMVMEYV SGGELFDYIC KHGRVEETEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAGA AGCCTCCTCC GCCGCAGAAG CACGACGGGC GCGTCAAGAT CGGCCACTAC 60
GTCTTGGGAG ACACGCTGGG CGTCGGCACC TTCGGCAAAG TCAAGAGCTG AGTATCTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0035404--P:histone-serine phosphorylation
GO:0035556--P:intracellular signal transduction
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	45.18	7.00e-121	427.00
IUUC-Aml-001907	Ailuropoda melanoleuca	79.51	0.00e+00	759.00
IUUC-Atr-002770	Amborella trichopoda	47.85	1.00e-124	439.00
IUUC-Apl-003395	Anas platyrhynchos	94.31	0.00e+00	971.00
IUUC-Aly-006289	Arabidopsis lyrata	47.13	5.00e-125	441.00
IUUC-Ath-007014	Arabidopsis thaliana	47.24	3.00e-125	442.00
IUUC-Ago-007957	Ashbya gossypii	42.46	4.00e-116	411.00
IUUC-Acl-008103	Aspergillus clavatus	60.07	8.00e-101	361.00
IUUC-Afl-008555	Aspergillus flavus	59.71	2.00e-101	363.00
IUUC-Afu-008949	Aspergillus fumigatus	60.07	5.00e-101	362.00
IUUC-Ani-009408	Aspergillus nidulans	62.17	1.00e-101	363.00
IUUC-Ang-009551	Aspergillus niger	60.07	7.00e-101	361.00
IUUC-Aor-010176	Aspergillus oryzae	59.71	2.00e-101	363.00
IUUC-Ate-010287	Aspergillus terreus	60.07	1.00e-100	360.00
IUUC-Ame-011019	Astyanax mexicanus	90.98	0.00e+00	979.00
IUUC-Bgr-012045	Blumeria graminis	59.93	1.00e-101	363.00
IUUC-Bta-012786	Bos taurus	79.71	0.00e+00	760.00
IUUC-Bci-013774	Botrytis cinerea	47.41	1.00e-103	370.00
IUUC-Bdi-015012	Brachypodium distachyon	47.24	1.00e-122	433.00
IUUC-Bol-016242	Brassica oleracea	47.52	1.00e-127	449.00
IUUC-Bra-016750	Brassica rapa	47.52	5.00e-128	451.00
IUUC-Cel-018518	Caenorhabditis elegans	64.48	2.00e-177	615.00
IUUC-Cja-019386	Callithrix jacchus	94.53	0.00e+00	1006.00
IUUC-Cfa-020177	Canis familiaris	78.57	0.00e+00	732.00
IUUC-Cpo-021805	Cavia porcellus	94.53	0.00e+00	1008.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	53.89	2.00e-94	338.00
IUUC-Csa-024267	Chlorocebus sabaeus	95.27	0.00e+00	1004.00
IUUC-Cho-024859	Choloepus hoffmanni	76.42	0.00e+00	719.00
IUUC-Cin-025550	Ciona intestinalis	64.73	0.00e+00	654.00
IUUC-Csv-026139	Ciona savignyi	64.51	0.00e+00	655.00
IUUC-Cne-027044	Cryptococcus neoformans	50.90	6.00e-108	384.00
IUUC-Cme-027289	Cyanidioschyzon merolae	44.86	2.00e-112	399.00
IUUC-Dre-027749	Danio rerio	76.28	0.00e+00	764.00
IUUC-Dno-030006	Dasypus novemcinctus	79.51	0.00e+00	758.00
IUUC-Dor-030578	Dipodomys ordii	93.95	0.00e+00	1003.00
IUUC-Dse-031507	Dothistroma septosporum	60.71	3.00e-104	372.00
IUUC-Dme-031704	Drosophila melanogaster	64.11	0.00e+00	641.00
IUUC-Ete-033055	Echinops telfairi	77.18	0.00e+00	776.00
IUUC-Eca-034016	Equus caballus	94.34	0.00e+00	944.00
IUUC-Fca-035754	Felis catus	77.34	0.00e+00	750.00
IUUC-Fal-037363	Ficedula albicollis	79.35	0.00e+00	749.00
IUUC-Fox-038073	Fusarium oxysporum	51.97	1.00e-103	370.00
IUUC-Fso-038236	Fusarium solani	51.55	2.00e-100	359.00
IUUC-Gmo-039633	Gadus morhua	75.59	0.00e+00	790.00
IUUC-Ggr-039987	Gaeumannomyces graminis	49.04	8.00e-102	364.00
IUUC-Gga-040546	Gallus gallus	94.90	0.00e+00	1018.00
IUUC-Gac-041822	Gasterosteus aculeatus	87.23	0.00e+00	919.00
IUUC-Gma-042712	Glycine max	46.94	1.00e-124	440.00
IUUC-Ggo-045303	Gorilla gorilla	94.73	0.00e+00	1009.00
IUUC-Hsa-045746	Homo sapiens	94.73	0.00e+00	1009.00
IUUC-Hvu-047406	Hordeum vulgare	45.13	8.00e-124	436.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	94.53	0.00e+00	1009.00
IUUC-Kpa-049190	Komagataella pastoris	45.27	7.00e-121	427.00
IUUC-Lch-049623	Latimeria chalumnae	78.48	0.00e+00	748.00
IUUC-Lpe-051392	Leersia perrieri	46.42	9.00e-124	436.00
IUUC-Loc-052928	Lepisosteus oculatus	92.93	0.00e+00	986.00
IUUC-Lma-053054	Leptosphaeria maculans	62.55	5.00e-105	375.00
IUUC-Laf-053459	Loxodonta africana	94.73	0.00e+00	1011.00
IUUC-Mcc-055862	Macaca mulatta	94.73	0.00e+00	1009.00
IUUC-Mor-057170	Magnaporthe oryzae	57.75	2.00e-100	360.00
IUUC-Mpo-057302	Magnaporthe poae	49.45	3.00e-102	365.00
IUUC-Mtr-058309	Medicago truncatula	46.54	2.00e-122	432.00
IUUC-Mla-059058	Melampsora laricipopulina	60.23	4.00e-94	338.00
IUUC-Mga-059206	Meleagris gallopavo	95.58	0.00e+00	960.00
IUUC-Mvi-060337	Microbotryum violaceum	47.06	8.00e-103	367.00
IUUC-Mmr-061619	Microcebus murinus	95.07	0.00e+00	1004.00
IUUC-Mdo-062160	Monodelphis domestica	93.95	0.00e+00	999.00
IUUC-Mmu-063406	Mus musculus	93.55	0.00e+00	995.00
IUUC-Mac-064518	Musa acuminata	45.03	3.00e-120	425.00
IUUC-Mpu-066326	Mustela putorius furo	94.97	0.00e+00	951.00
IUUC-Mlu-067968	Myotis lucifugus	93.39	0.00e+00	914.00
IUUC-Nfi-068493	Neosartorya fischeri	60.07	4.00e-101	362.00
IUUC-Ncr-068665	Neurospora crassa	41.96	9.00e-107	380.00
IUUC-Nle-070158	Nomascus leucogenys	94.53	0.00e+00	1008.00
IUUC-Opr-070272	Ochotona princeps	77.14	0.00e+00	748.00
IUUC-Ont-071395	Oreochromis niloticus	89.45	0.00e+00	957.00
IUUC-Oan-073322	Ornithorhynchus anatinus	72.82	0.00e+00	719.00
IUUC-Ocu-074188	Oryctolagus cuniculus	76.61	0.00e+00	751.00
IUUC-Oba-075436	Oryza barthii	45.98	5.00e-124	437.00
IUUC-Obr-076507	Oryza brachyantha	45.88	1.00e-124	439.00
IUUC-Ogl-077718	Oryza glaberrima	46.22	3.00e-123	434.00
IUUC-Ogu-078349	Oryza glumaepatula	45.11	1.00e-124	439.00
IUUC-Oin-079889	Oryza indica	46.00	3.00e-124	438.00
IUUC-Olo-080521	Oryza longistaminata	45.98	5.00e-124	437.00
IUUC-Ome-081630	Oryza meridionalis	45.78	1.00e-123	436.00
IUUC-Oni-082211	Oryza nivara	45.98	2.00e-124	439.00
IUUC-Opu-083617	Oryza punctata	45.89	5.00e-124	437.00
IUUC-Oru-084252	Oryza rufipogon	45.98	5.00e-124	437.00
IUUC-Osa-085548	Oryza sativa	45.98	5.00e-124	437.00
IUUC-Ola-087169	Oryzias latipes	87.50	0.00e+00	939.00
IUUC-Olu-087861	Ostreococcus lucimarinus	42.41	2.00e-115	409.00
IUUC-Oga-088003	Otolemur garnettii	79.71	0.00e+00	759.00
IUUC-Oar-089933	Ovis aries	79.71	0.00e+00	760.00
IUUC-Ptr-090741	Pan troglodytes	94.73	0.00e+00	1009.00
IUUC-Pan-092526	Papio anubis	78.09	0.00e+00	759.00
IUUC-Psi-094034	Pelodiscus sinensis	78.94	0.00e+00	748.00
IUUC-Pno-095030	Phaeosphaeria nodorum	62.17	4.00e-103	368.00
IUUC-Ppa-095615	Physcomitrella patens	43.94	5.00e-122	431.00
IUUC-Pfo-096295	Poecilia formosa	89.06	0.00e+00	953.00
IUUC-Pab-098023	Pongo abelii	94.73	0.00e+00	1009.00
IUUC-Pop-100042	Populus trichocarpa	47.18	2.00e-126	445.00
IUUC-Pca-101104	Procavia capensis	78.91	6.00e-173	600.00
IUUC-Ppe-101642	Prunus persica	46.25	1.00e-123	436.00
IUUC-Pva-102470	Pteropus vampyrus	94.31	0.00e+00	995.00
IUUC-Pgr-103406	Puccinia graminis	61.36	8.00e-92	331.00
IUUC-Ptt-103713	Puccinia triticina	37.36	6.00e-79	288.00
IUUC-Pte-104259	Pyrenophora teres	62.17	2.00e-104	373.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	62.55	6.00e-105	375.00
IUUC-Rno-104960	Rattus norvegicus	93.95	0.00e+00	1003.00
IUUC-Sce-106290	Saccharomyces cerevisiae	42.10	2.00e-116	412.00
IUUC-Sha-107603	Sarcophilus harrisii	79.51	0.00e+00	756.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	40.19	4.00e-108	385.00
IUUC-Spo-108202	Schizosaccharomyces pombe	40.35	6.00e-107	380.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	47.02	2.00e-102	366.00
IUUC-Smo-109309	Selaginella moellendorffii	45.38	6.00e-122	431.00
IUUC-Sit-109745	Setaria italica	47.03	1.00e-125	442.00
IUUC-Sly-110890	Solanum lycopersicum	47.29	5.00e-125	441.00
IUUC-Stu-112144	Solanum tuberosum	44.69	2.00e-116	412.00
IUUC-Sar-113521	Sorex araneus	68.70	1.00e-174	605.00
IUUC-Sbi-114764	Sorghum bicolor	46.86	3.00e-126	445.00
IUUC-Sre-115141	Sporisorium reilianum	66.18	1.00e-113	403.00
IUUC-Ssc-115732	Sus scrofa	78.74	0.00e+00	729.00
IUUC-Tgu-117190	Taeniopygia guttata	79.35	0.00e+00	748.00
IUUC-Tru-118735	Takifugu rubripes	88.48	0.00e+00	950.00
IUUC-Tsy-119503	Tarsius syrichta	91.60	0.00e+00	895.00
IUUC-Tni-119880	Tetraodon nigroviridis	87.31	0.00e+00	952.00
IUUC-Tca-121386	Theobroma cacao	47.36	5.00e-126	444.00
IUUC-Tre-122070	Trichoderma reesei	48.43	6.00e-102	364.00
IUUC-Tvi-122305	Trichoderma virens	50.00	3.00e-101	362.00
IUUC-Tae-123515	Triticum aestivum	47.43	1.00e-124	439.00
IUUC-Tur-126416	Triticum urartu	44.84	1.00e-122	432.00
IUUC-Tme-127174	Tuber melanosporum	53.15	9.00e-67	247.00
IUUC-Tbe-127791	Tupaia belangeri	85.22	8.00e-112	396.00
IUUC-Ttr-129224	Tursiops truncatus	77.53	0.00e+00	751.00
IUUC-Uma-129372	Ustilago maydis	66.18	6.00e-113	401.00
IUUC-Vda-129819	Verticillium dahliae	52.63	2.00e-84	306.00
IUUC-Vpa-130220	Vicugna pacos	94.75	0.00e+00	947.00
IUUC-Vvi-131649	Vitis vinifera	47.57	2.00e-124	439.00
IUUC-Xtr-132954	Xenopus tropicalis	93.00	0.00e+00	1001.00
IUUC-Xma-134119	Xiphophorus maculatus	88.87	0.00e+00	953.00
IUUC-Yli-134422	Yarrowia lipolytica	44.81	2.00e-118	419.00
IUUC-Zma-135621	Zea mays	61.37	7.00e-119	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence