iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053650

Ensembl Protein ID

ENSLAFP00000028461.1

UniProt Accession

G3UKV2; G3UKV2_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TNIP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000027379.1	ENSLAFT00000028967.1	ENSLAFP00000028461.1
ENSLAFG00000027379.1	ENSLAFT00000026073.1	ENSLAFP00000027954.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	3.10e-18	65.8	214	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvskln 54
           ++++le+v++L+qQ+ +Yk+DF +ERadREr++++ +eL   v+ lq+qv + +
   Q: 214  RDAALERVQMLEQQILVYKDDFSSERADRERAQSRFQELWDMVACLQRQVPRTQ 267
           6899*********************************************98765 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

EIKRLNERLE EKERKTQALR EPLCAREEER ALQARAWATS DVLCRSLASE AHQLRRTLAA 60
TAHMCQQLAQ CLEERQREGR GAETPKEVVS LLCTKTTTVD TPVCKQLWPE HTSRDAAIQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGATCAAGA GGCTGAATGA GCGGCTGGAG GAGAAGGAGA GGAAGACGCA GGCGCTGAGG 60
GAGCCACTGT GCGCCAGGGA GGAGGAGCGA GCTCTGCAGG CGCGTGCCTG GGCCACCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR022008--EABR
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF12180--EABR

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0023035--P:CD40 signaling pathway
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:0050871--P:positive regulation of B cell activation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043032--P:positive regulation of macrophage activation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0050821--P:protein stabilization
GO:0034134--P:toll-like receptor 2 signaling pathway
GO:0034138--P:toll-like receptor 3 signaling pathway
GO:0034162--P:toll-like receptor 9 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001697	Ailuropoda melanoleuca	56.45	1.00e-90	326.00
IUUC-Apl-003896	Anas platyrhynchos	42.06	1.00e-69	256.00
IUUC-Ame-011223	Astyanax mexicanus	33.33	1.00e-35	144.00
IUUC-Bta-012996	Bos taurus	55.62	8.00e-83	300.00
IUUC-Cja-019376	Callithrix jacchus	52.29	4.00e-79	288.00
IUUC-Cfa-021027	Canis familiaris	54.75	1.00e-86	313.00
IUUC-Cpo-021372	Cavia porcellus	54.18	1.00e-69	256.00
IUUC-Csa-023221	Chlorocebus sabaeus	57.23	2.00e-89	322.00
IUUC-Dre-028604	Danio rerio	36.34	1.00e-42	167.00
IUUC-Dno-029976	Dasypus novemcinctus	61.19	1.00e-45	176.00
IUUC-Dor-030364	Dipodomys ordii	51.84	2.00e-49	189.00
IUUC-Eca-033582	Equus caballus	55.53	4.00e-84	304.00
IUUC-Eeu-034751	Erinaceus europaeus	56.40	2.00e-48	185.00
IUUC-Fca-036086	Felis catus	54.26	4.00e-87	314.00
IUUC-Fal-036828	Ficedula albicollis	43.16	7.00e-73	267.00
IUUC-Gmo-038838	Gadus morhua	35.91	1.00e-30	127.00
IUUC-Gga-041179	Gallus gallus	41.78	1.00e-68	253.00
IUUC-Gac-042266	Gasterosteus aculeatus	33.33	2.00e-33	136.00
IUUC-Ggo-044971	Gorilla gorilla	58.59	3.00e-89	322.00
IUUC-Hsa-045772	Homo sapiens	56.00	7.00e-83	300.00
IUUC-Itr-048993	Ictidomys tridecemlineatus	53.58	4.00e-82	298.00
IUUC-Lch-049851	Latimeria chalumnae	38.83	1.00e-44	174.00
IUUC-Loc-052551	Lepisosteus oculatus	36.34	8.00e-36	144.00
IUUC-Mcc-054744	Macaca mulatta	57.85	2.00e-89	322.00
IUUC-Meu-056799	Macropus eugenii	43.14	8.00e-26	110.00
IUUC-Mga-060124	Meleagris gallopavo	41.58	6.00e-69	254.00
IUUC-Mmr-061466	Microcebus murinus	59.01	4.00e-89	321.00
IUUC-Mdo-062389	Monodelphis domestica	46.09	5.00e-76	278.00
IUUC-Mmu-064000	Mus musculus	55.01	6.00e-90	324.00
IUUC-Mpu-066109	Mustela putorius furo	52.99	3.00e-85	308.00
IUUC-Mlu-067666	Myotis lucifugus	55.42	2.00e-54	205.00
IUUC-Nle-069689	Nomascus leucogenys	54.15	1.00e-89	323.00
IUUC-Opr-070774	Ochotona princeps	43.83	1.00e-37	149.00
IUUC-Ont-072439	Oreochromis niloticus	37.95	5.00e-47	181.00
IUUC-Oan-072817	Ornithorhynchus anatinus	46.61	2.00e-48	184.00
IUUC-Ocu-074621	Oryctolagus cuniculus	50.69	1.00e-52	200.00
IUUC-Ola-087305	Oryzias latipes	35.04	4.00e-42	165.00
IUUC-Oga-087920	Otolemur garnettii	55.32	5.00e-86	311.00
IUUC-Oar-090351	Ovis aries	57.50	3.00e-13	66.20
IUUC-Ptr-090879	Pan troglodytes	58.87	4.00e-67	248.00
IUUC-Pan-092022	Papio anubis	57.23	2.00e-89	322.00
IUUC-Psi-093302	Pelodiscus sinensis	41.53	1.00e-66	246.00
IUUC-Pfo-097250	Poecilia formosa	41.45	5.00e-39	155.00
IUUC-Pab-097929	Pongo abelii	55.34	2.00e-90	325.00
IUUC-Pca-100271	Procavia capensis	82.39	5.00e-55	207.00
IUUC-Pva-102234	Pteropus vampyrus	52.07	1.00e-65	243.00
IUUC-Rno-105850	Rattus norvegicus	54.77	6.00e-91	327.00
IUUC-Sha-107375	Sarcophilus harrisii	45.33	5.00e-73	268.00
IUUC-Ssc-116269	Sus scrofa	56.27	1.00e-82	300.00
IUUC-Tgu-116960	Taeniopygia guttata	42.43	3.00e-72	265.00
IUUC-Tru-118002	Takifugu rubripes	31.48	4.00e-33	135.00
IUUC-Tni-120023	Tetraodon nigroviridis	34.97	4.00e-41	162.00
IUUC-Tbe-127592	Tupaia belangeri	52.81	8.00e-81	293.00
IUUC-Ttr-128362	Tursiops truncatus	50.96	2.00e-68	252.00
IUUC-Vpa-130399	Vicugna pacos	55.65	4.00e-83	301.00
IUUC-Xtr-132677	Xenopus tropicalis	38.56	1.00e-54	207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence