iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132192

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

EF-hand calcium-binding domain 8

Genbank Nucleotide ID

AAMC01064855

Gene Name

efcab8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000016236.3	ENSXETT00000035453.3	ENSXETP00000035453.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-35	119.3	147	181
UBD/Beta-Prp	4.10e-64	216.8	12	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd..tllvsGsdDgtikvWDlrtg 33
           +H ++vtcl +s+  +l+v+Gs D t+ vWD+ tg
   Q: 147  THRAPVTCLLYSSfcHLIVTGSEDSTVAVWDVETG 181
           599******884444889**************998 PP

UBD/Beta-Prp

   S: 53   aevtavkfspdgkilvtgseDrtikvw.dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee......... 131
           ++v++ ++ +  ++lvtg+ D+ +++w  + t+ ++ +l +h+  +l++ +++    + s s+d++++vwd+++++cl++         
   Q: 12   KGVQCFDYCRALNLLVTGGFDHKVRLWnQYVTCRPIAVLPEHSMAILDVMIYQPLGQIFSFSKDSVLKVWDIPSQTCLHTlvlkfpciq 100
           7899***********************8899********************************************************** PP
   S: 132  ...........................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
                                                      t+  h++ v+c+ +++++ l+v+Gs D+tv +Wd++tg     l  
   Q: 101  pgriqeqgsfpfllvptnpsrllvcysdyigilrlaraeptegTFFTHRAPVTCLLYSSFCHLIVTGSEDSTVAVWDVETGAKSLLLGN 189
           ******************************************************************************99877666644 PP
   S: 178  gh.tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng.htdnvksvrfspnderlvsgssDgsiriWdlrsg 254
           +h ++ v+++++d+ +++l++g+++gt+k+w++q+g+ +++l+   ++ ++++ +s +++ +++++  + i  +d+ + 
   Q: 190  AHgQEEVTCMALDKAQRRLITGARNGTIKIWNIQNGHNLHQLEPvEDAEITCIVAS-QENVFLTVGWNRKIVTYDIPKT 267
           441678************************************99455889999999.8889999999999999988665 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

QKGKVYTWKI NKGVQCFDYC RALNLLVTGG FDHKVRLWNQ YVTCRPIAVL PEHSMAILDV 60
MIYQPLGQIF SFSKDSVLKV WDIPSQTCLH TLVLKFPCIQ PGRIQEQGSF PFLLVPTNPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAAGGGAA AGGTTTATAC GTGGAAGATT AACAAGGTGG GACGCACATA TTAACCCCAT 60
TACATACAGT CATTCCCCAG GTTACAATAG TATACAAAGT ATCAGGTATC AGGGGCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cin-025187	Ciona intestinalis	43.70	3.00e-124	439.00
IUUC-Dre-027920	Danio rerio	44.38	3.00e-111	396.00
IUUC-Dme-031984	Drosophila melanogaster	25.26	5.00e-43	169.00
IUUC-Fal-037351	Ficedula albicollis	33.91	2.00e-28	120.00
IUUC-Gmo-039225	Gadus morhua	40.04	5.00e-101	361.00
IUUC-Gga-041212	Gallus gallus	29.24	3.00e-24	107.00
IUUC-Lch-050151	Latimeria chalumnae	55.81	4.00e-156	545.00
IUUC-Loc-052558	Lepisosteus oculatus	56.44	7.00e-166	577.00
IUUC-Mcc-054635	Macaca mulatta	33.02	2.00e-40	161.00
IUUC-Mmr-061370	Microcebus murinus	32.70	5.00e-40	160.00
IUUC-Mdo-062601	Monodelphis domestica	50.48	9.00e-136	477.00
IUUC-Ont-072106	Oreochromis niloticus	43.47	2.00e-117	416.00
IUUC-Ocu-074664	Oryctolagus cuniculus	30.31	2.00e-38	154.00
IUUC-Ppa-095538	Physcomitrella patens	27.95	2.00e-14	74.30
IUUC-Pca-100863	Procavia capensis	25.70	7.00e-20	92.80
IUUC-Tru-117878	Takifugu rubripes	40.39	1.00e-100	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence