iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115555

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

CU464004

Gene Name

DCUN1D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000007854.2	ENSSSCT00000008604.2	ENSSSCP00000008383.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.10e-84	283.5	87	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s ++leelf+rYkd++ed+i++eg+e+fc+dl+vdp++++vL+lawk++aat+c+f+r+ef+dg++a+++dsi+++++++++l +e+k+
   Q: 87   SLQRLEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEFFDGCKAISADSIDGICARFPSLLTEAKQ 175
           679************************************************************************************** PP
   S: 91   eqkfkdiYrfafnfakd..kgqksldldtaialwkLllaerefklldawlkfLeee..kkksiskDtWnllLefskviakdlsnYdeeg 175
           e+kfkd+Yrf+f+f++d  +gq+sl++++aialwkL+++++++++ld+wl+fL+e+  ++k+is+DtWn++L+f++vi +dlsnY+e++
   Q: 176  EDKFKDLYRFTFQFGLDseEGQRSLHREIAIALWKLVFTQNNPPVLDQWLNFLTENpsGIKGISRDTWNMFLNFTQVIGPDLSNYSEDE 264
           ***************998899**********************************9889****************************** PP
   S: 176  aWPvliDefveylk 189
           aWP+l+D+fve+++
   Q: 265  AWPSLFDTFVEWEM 278
           ************85 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MGQCVTKCKN PSSTLGSKNG DRDPSSKSYS RRGAGHREEQ LPACGKPGGD ILVNGTKKAE 60
AAAEACQLPT SSGDAGREPK SNAEESSLQR LEELFRRYKD EREDAILEEG MERFCNDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGGAATTT TCCTTAATGC TTCTCCATAT GTGCTCTAGC CTTTGCATTT CCAAGGCGAA 60
AGTGTAAGCT TGCAAGAGGG GATAGTGATG AACTTGGGGC ATCTCCCCTG ATTCATGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005737--C:cytoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0030308--P:negative regulation of cell growth
GO:0043065--P:positive regulation of apoptotic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
GO:0010332--P:response to gamma radiation
GO:0009314--P:response to radiation
GO:0010225--P:response to UV-C

KEGG

ssc:100525983

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	97.70	5.00e-163	566.00
IUUC-Apl-003497	Anas platyrhynchos	81.91	3.00e-138	484.00
IUUC-Aca-004961	Anolis carolinensis	80.59	3.00e-143	500.00
IUUC-Aor-009902	Aspergillus oryzae	33.83	2.00e-11	60.80
IUUC-Ame-011413	Astyanax mexicanus	64.31	2.00e-99	354.00
IUUC-Bta-013338	Bos taurus	97.70	6.00e-163	565.00
IUUC-Cja-019458	Callithrix jacchus	97.37	1.00e-162	565.00
IUUC-Cfa-020160	Canis familiaris	98.03	9.00e-164	568.00
IUUC-Cpo-021835	Cavia porcellus	96.71	3.00e-152	530.00
IUUC-Csa-023328	Chlorocebus sabaeus	97.70	3.00e-163	566.00
IUUC-Cho-024888	Choloepus hoffmanni	95.70	3.00e-161	560.00
IUUC-Cin-025134	Ciona intestinalis	52.24	6.00e-60	224.00
IUUC-Csv-025904	Ciona savignyi	50.41	2.00e-32	130.00
IUUC-Dre-027780	Danio rerio	64.75	1.00e-94	338.00
IUUC-Dno-028866	Dasypus novemcinctus	97.37	7.00e-162	562.00
IUUC-Dor-030387	Dipodomys ordii	96.38	4.00e-160	556.00
IUUC-Dme-032081	Drosophila melanogaster	47.17	4.00e-48	184.00
IUUC-Eca-033857	Equus caballus	97.37	7.00e-163	565.00
IUUC-Eeu-034825	Erinaceus europaeus	89.80	6.00e-147	513.00
IUUC-Fca-036130	Felis catus	98.03	3.00e-164	570.00
IUUC-Fal-037296	Ficedula albicollis	82.24	6.00e-138	483.00
IUUC-Gmo-039626	Gadus morhua	64.41	6.00e-96	343.00
IUUC-Ggr-039959	Gaeumannomyces graminis	26.64	3.00e-15	76.60
IUUC-Gga-040741	Gallus gallus	81.25	2.00e-134	471.00
IUUC-Gac-042271	Gasterosteus aculeatus	66.91	1.00e-89	322.00
IUUC-Ggo-044727	Gorilla gorilla	97.70	3.00e-163	566.00
IUUC-Hsa-046288	Homo sapiens	97.37	1.00e-162	565.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	97.04	4.00e-171	593.00
IUUC-Lch-050289	Latimeria chalumnae	78.03	6.00e-129	452.00
IUUC-Loc-052455	Lepisosteus oculatus	72.30	1.00e-105	375.00
IUUC-Laf-054369	Loxodonta africana	96.05	2.00e-154	537.00
IUUC-Mcc-055413	Macaca mulatta	77.92	8.00e-116	409.00
IUUC-Meu-056535	Macropus eugenii	86.51	2.00e-148	517.00
IUUC-Mga-059290	Meleagris gallopavo	81.91	2.00e-136	478.00
IUUC-Mmr-060689	Microcebus murinus	97.37	2.00e-162	564.00
IUUC-Mdo-062128	Monodelphis domestica	86.84	9.00e-144	502.00
IUUC-Mmu-064396	Mus musculus	95.72	9.00e-169	585.00
IUUC-Mpu-065926	Mustela putorius furo	97.70	5.00e-163	566.00
IUUC-Mlu-067044	Myotis lucifugus	95.72	2.00e-168	584.00
IUUC-Nle-069346	Nomascus leucogenys	97.70	3.00e-163	566.00
IUUC-Opr-070682	Ochotona princeps	97.37	1.00e-150	525.00
IUUC-Ont-071772	Oreochromis niloticus	67.74	2.00e-98	351.00
IUUC-Oan-072765	Ornithorhynchus anatinus	83.88	2.00e-140	491.00
IUUC-Ocu-074272	Oryctolagus cuniculus	92.31	1.00e-118	418.00
IUUC-Ola-087561	Oryzias latipes	69.10	7.00e-104	369.00
IUUC-Oga-088440	Otolemur garnettii	77.03	1.00e-120	425.00
IUUC-Oar-089403	Ovis aries	98.03	1.00e-163	568.00
IUUC-Ptr-091384	Pan troglodytes	97.70	3.00e-163	566.00
IUUC-Pan-092650	Papio anubis	97.70	3.00e-163	566.00
IUUC-Psi-093806	Pelodiscus sinensis	82.89	2.00e-132	464.00
IUUC-Pma-094196	Petromyzon marinus	52.06	2.00e-88	318.00
IUUC-Pfo-096584	Poecilia formosa	70.11	5.00e-102	363.00
IUUC-Pab-098605	Pongo abelii	97.70	3.00e-163	566.00
IUUC-Pca-100933	Procavia capensis	79.28	5.00e-112	396.00
IUUC-Pva-102172	Pteropus vampyrus	93.16	2.00e-157	548.00
IUUC-Rno-105406	Rattus norvegicus	96.71	1.00e-170	591.00
IUUC-Sha-106531	Sarcophilus harrisii	86.18	2.00e-149	520.00
IUUC-Sar-113051	Sorex araneus	76.64	2.00e-114	404.00
IUUC-Tgu-117178	Taeniopygia guttata	82.57	4.00e-139	486.00
IUUC-Tru-117876	Takifugu rubripes	67.48	5.00e-103	367.00
IUUC-Tsy-118790	Tarsius syrichta	95.36	2.00e-129	454.00
IUUC-Tni-119673	Tetraodon nigroviridis	67.94	3.00e-103	367.00
IUUC-Tbe-127429	Tupaia belangeri	97.37	1.00e-162	565.00
IUUC-Ttr-128467	Tursiops truncatus	98.36	8.00e-165	572.00
IUUC-Vpa-130376	Vicugna pacos	68.73	2.00e-93	334.00
IUUC-Xtr-132134	Xenopus tropicalis	79.64	1.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence