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Tag Content
iUUCD ID IUUC-Cfa-020132
Ensembl Protein ID ENSCAFP00000021613.3
UniProt Accession F1P8Q1; F1P8Q1_CANLF
Genbank Protein ID ENSCAFP00000021613
Protein Name Protein HIRA
Genbank Nucleotide ID AAEX03014866
Gene Name HIRA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000014619.4 ENSCAFT00000043980.2 ENSCAFP00000036285.1
ENSCAFG00000014619.4 ENSCAFT00000023274.3 ENSCAFP00000021613.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.80e-20 70.7 69 98
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ i+vW 
   Q: 69   HLACVNCVRWsNSgMYLASGGDDKLIMVWK 98
           8899******955699*************7 PP
   
Organism Canis familiaris
Functional Description
(View)

Functional Description


     Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
 Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Protein Sequence
(Fasta)
LKLLDHCSFK FPGKPIFSVD IHPDGTKFAT GGQGQDSGKV VIWNMSPVLQ EDDEKDENIP 60
KMLCQMDNHL ACVNCVRWSN SGMYLASGGD DKLIMVWKRA TYIGPSTVFG SSGKLANVEQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020132|E3,WD_repeat|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAAGCTCC TGAAGCCGAC CTGGGTCAAC CACAATGGTG AGTGCGCGCA GGGGTCGCGG 60
GTGGCCGAGC CCGGAGTCGG GTCGGGGTCT GCGGGAAGGT CCGAGCGGCG CGCAGGCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020132|E3,WD_repeat|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001039 Aegilops tauschii 39.57 1.00e-85 311.00
IUUC-Aml-001723 Ailuropoda melanoleuca 99.21 0.00e+00 1833.00
IUUC-Atr-003132 Amborella trichopoda 36.18 1.00e-84 308.00
IUUC-Apl-003197 Anas platyrhynchos 84.28 0.00e+00 1621.00
IUUC-Aca-004733 Anolis carolinensis 81.68 0.00e+00 1564.00
IUUC-Aly-005446 Arabidopsis lyrata 35.16 9.00e-79 288.00
IUUC-Ath-007627 Arabidopsis thaliana 36.36 3.00e-82 300.00
IUUC-Ago-007766 Ashbya gossypii 31.30 6.00e-57 216.00
IUUC-Acl-008104 Aspergillus clavatus 32.80 6.00e-60 226.00
IUUC-Afl-008591 Aspergillus flavus 29.96 1.00e-60 228.00
IUUC-Afu-008781 Aspergillus fumigatus 33.33 3.00e-58 220.00
IUUC-Ani-009272 Aspergillus nidulans 28.57 3.00e-53 204.00
IUUC-Ang-009655 Aspergillus niger 33.51 3.00e-61 230.00
IUUC-Aor-010119 Aspergillus oryzae 29.96 3.00e-61 230.00
IUUC-Ate-010530 Aspergillus terreus 27.66 4.00e-54 206.00
IUUC-Ame-011147 Astyanax mexicanus 78.00 4.00e-46 175.00
IUUC-Bgr-012237 Blumeria graminis 33.33 1.00e-58 221.00
IUUC-Bta-013320 Bos taurus 92.09 0.00e+00 1785.00
IUUC-Bci-013795 Botrytis cinerea 33.77 2.00e-63 238.00
IUUC-Bdi-014075 Brachypodium distachyon 42.01 3.00e-88 320.00
IUUC-Bol-016440 Brassica oleracea 34.97 1.00e-85 311.00
IUUC-Bra-016651 Brassica rapa 40.31 1.00e-83 305.00
IUUC-Cel-018692 Caenorhabditis elegans 38.04 2.00e-73 270.00
IUUC-Cja-018987 Callithrix jacchus 96.72 0.00e+00 1704.00
IUUC-Cpo-021484 Cavia porcellus 95.28 0.00e+00 1774.00
IUUC-Cre-022846 Chlamydomonas reinhardtii 36.00 2.00e-59 224.00
IUUC-Csa-023081 Chlorocebus sabaeus 96.07 0.00e+00 1777.00
IUUC-Cin-025182 Ciona intestinalis 51.42 6.00e-151 528.00
IUUC-Csv-026154 Ciona savignyi 55.70 7.00e-147 514.00
IUUC-Cgl-026655 Colletotrichum gloeosporioides 33.76 3.00e-61 230.00
IUUC-Cne-026891 Cryptococcus neoformans 41.55 3.00e-80 293.00
IUUC-Cme-027349 Cyanidioschyzon merolae 29.37 6.00e-53 202.00
IUUC-Dre-027655 Danio rerio 68.52 0.00e+00 1328.00
IUUC-Dno-029557 Dasypus novemcinctus 85.28 0.00e+00 1110.00
IUUC-Dor-030687 Dipodomys ordii 85.65 0.00e+00 725.00
IUUC-Dse-031334 Dothistroma septosporum 30.69 1.00e-59 225.00
IUUC-Dme-031746 Drosophila melanogaster 54.24 2.00e-152 533.00
IUUC-Ete-032384 Echinops telfairi 89.54 0.00e+00 1639.00
IUUC-Eca-033430 Equus caballus 97.91 0.00e+00 1786.00
IUUC-Fca-036121 Felis catus 98.71 0.00e+00 1811.00
IUUC-Fal-036817 Ficedula albicollis 84.27 0.00e+00 1619.00
IUUC-Fox-037906 Fusarium oxysporum 35.09 1.00e-65 244.00
IUUC-Fso-038409 Fusarium solani 33.83 9.00e-64 238.00
IUUC-Gmo-039151 Gadus morhua 84.37 0.00e+00 680.00
IUUC-Ggr-040016 Gaeumannomyces graminis 31.98 2.00e-66 248.00
IUUC-Gga-040936 Gallus gallus 84.86 0.00e+00 1686.00
IUUC-Gac-041405 Gasterosteus aculeatus 62.08 0.00e+00 1173.00
IUUC-Gma-044252 Glycine max 36.35 3.00e-87 316.00
IUUC-Ggo-045430 Gorilla gorilla 95.58 0.00e+00 1765.00
IUUC-Hsa-046442 Homo sapiens 95.67 0.00e+00 1769.00
IUUC-Hvu-047587 Hordeum vulgare 37.34 1.00e-80 295.00
IUUC-Itr-048910 Ictidomys tridecemlineatus 100.00 1.00e-175 608.00
IUUC-Kpa-049145 Komagataella pastoris 31.36 4.00e-59 223.00
IUUC-Lch-050474 Latimeria chalumnae 75.70 0.00e+00 1400.00
IUUC-Lpe-051209 Leersia perrieri 35.06 3.00e-80 293.00
IUUC-Loc-052119 Lepisosteus oculatus 71.86 0.00e+00 1350.00
IUUC-Lma-053237 Leptosphaeria maculans 33.33 7.00e-65 242.00
IUUC-Laf-053718 Loxodonta africana 94.40 0.00e+00 1755.00
IUUC-Mcc-055621 Macaca mulatta 96.61 0.00e+00 1705.00
IUUC-Meu-055914 Macropus eugenii 79.39 0.00e+00 1429.00
IUUC-Mor-057090 Magnaporthe oryzae 34.09 7.00e-64 239.00
IUUC-Mpo-057364 Magnaporthe poae 32.43 6.00e-69 256.00
IUUC-Mtr-057744 Medicago truncatula 37.65 5.00e-88 319.00
IUUC-Mla-058914 Melampsora laricipopulina 41.74 1.00e-80 294.00
IUUC-Mga-060181 Meleagris gallopavo 83.81 0.00e+00 1650.00
IUUC-Mvi-060432 Microbotryum violaceum 38.50 9.00e-73 268.00
IUUC-Mmr-060871 Microcebus murinus 95.58 0.00e+00 1826.00
IUUC-Mdo-062301 Monodelphis domestica 85.32 0.00e+00 1596.00
IUUC-Mmu-063888 Mus musculus 94.10 0.00e+00 1738.00
IUUC-Mac-065137 Musa acuminata 38.65 1.00e-86 315.00
IUUC-Mpu-066732 Mustela putorius furo 98.72 0.00e+00 1859.00
IUUC-Mlu-067542 Myotis lucifugus 97.51 0.00e+00 1753.00
IUUC-Nfi-068396 Neosartorya fischeri 33.99 3.00e-58 220.00
IUUC-Ncr-068842 Neurospora crassa 32.25 2.00e-64 240.00
IUUC-Nle-070156 Nomascus leucogenys 95.97 0.00e+00 1787.00
IUUC-Opr-070808 Ochotona princeps 95.39 0.00e+00 1434.00
IUUC-Ont-072105 Oreochromis niloticus 67.19 0.00e+00 1303.00
IUUC-Ocu-074962 Oryctolagus cuniculus 96.72 0.00e+00 1787.00
IUUC-Oba-075178 Oryza barthii 41.49 6.00e-87 315.00
IUUC-Obr-076399 Oryza brachyantha 36.50 1.00e-88 321.00
IUUC-Ogu-078797 Oryza glumaepatula 41.49 6.00e-87 315.00
IUUC-Oin-080085 Oryza indica 40.80 7.00e-78 285.00
IUUC-Olo-081048 Oryza longistaminata 41.04 4.00e-66 246.00
IUUC-Ome-081324 Oryza meridionalis 41.49 5.00e-87 316.00
IUUC-Oni-082548 Oryza nivara 41.49 5.00e-87 316.00
IUUC-Opu-084008 Oryza punctata 41.49 5.00e-87 316.00
IUUC-Oru-084339 Oryza rufipogon 41.24 2.00e-86 314.00
IUUC-Osa-085782 Oryza sativa 41.24 2.00e-86 314.00
IUUC-Ola-087302 Oryzias latipes 67.39 0.00e+00 787.00
IUUC-Olu-087611 Ostreococcus lucimarinus 36.20 5.00e-87 315.00
IUUC-Oga-087935 Otolemur garnettii 95.17 0.00e+00 1752.00
IUUC-Oar-089229 Ovis aries 70.87 0.00e+00 1064.00
IUUC-Ptr-090715 Pan troglodytes 95.77 0.00e+00 1772.00
IUUC-Pan-092318 Papio anubis 96.83 0.00e+00 1778.00
IUUC-Psi-094053 Pelodiscus sinensis 84.40 0.00e+00 1624.00
IUUC-Pno-094985 Phaeosphaeria nodorum 33.51 1.00e-56 215.00
IUUC-Ppa-095819 Physcomitrella patens 34.99 1.00e-85 311.00
IUUC-Pfo-096857 Poecilia formosa 65.74 0.00e+00 1255.00
IUUC-Pab-098047 Pongo abelii 95.97 0.00e+00 1775.00
IUUC-Pop-099865 Populus trichocarpa 36.99 1.00e-85 311.00
IUUC-Pca-100558 Procavia capensis 95.06 0.00e+00 746.00
IUUC-Ppe-101261 Prunus persica 37.29 3.00e-87 317.00
IUUC-Pva-102683 Pteropus vampyrus 97.61 0.00e+00 1805.00
IUUC-Pgr-103660 Puccinia graminis 41.21 4.00e-74 273.00
IUUC-Ptt-103900 Puccinia triticina 42.53 1.00e-75 277.00
IUUC-Pte-104209 Pyrenophora teres 34.15 1.00e-61 231.00
IUUC-Pyt-104802 Pyrenophora triticirepentis 32.30 5.00e-61 229.00
IUUC-Rno-105137 Rattus norvegicus 94.36 0.00e+00 1767.00
IUUC-Sce-106291 Saccharomyces cerevisiae 29.94 3.00e-60 226.00
IUUC-Sha-107514 Sarcophilus harrisii 81.05 0.00e+00 1487.00
IUUC-Sja-107833 Schizosaccharomyces japonicus 35.02 3.00e-78 286.00
IUUC-Spo-108162 Schizosaccharomyces pombe 36.93 2.00e-76 281.00
IUUC-Smo-109186 Selaginella moellendorffii 40.41 5.00e-86 312.00
IUUC-Sit-109980 Setaria italica 37.02 4.00e-89 323.00
IUUC-Sly-111547 Solanum lycopersicum 37.99 1.00e-89 325.00
IUUC-Stu-112705 Solanum tuberosum 37.99 7.00e-90 325.00
IUUC-Sar-113222 Sorex araneus 90.99 0.00e+00 1563.00
IUUC-Sbi-114272 Sorghum bicolor 37.58 4.00e-90 326.00
IUUC-Sre-115061 Sporisorium reilianum 27.54 6.00e-94 338.00
IUUC-Ssc-116364 Sus scrofa 95.74 0.00e+00 1867.00
IUUC-Tgu-116645 Taeniopygia guttata 84.67 0.00e+00 1642.00
IUUC-Tru-117590 Takifugu rubripes 65.49 0.00e+00 1267.00
IUUC-Tsy-119212 Tarsius syrichta 91.35 0.00e+00 996.00
IUUC-Tni-119915 Tetraodon nigroviridis 66.23 0.00e+00 1248.00
IUUC-Tca-121765 Theobroma cacao 37.10 5.00e-87 316.00
IUUC-Tre-121887 Trichoderma reesei 29.73 5.00e-57 216.00
IUUC-Tvi-122262 Trichoderma virens 34.02 2.00e-56 214.00
IUUC-Tae-124148 Triticum aestivum 43.82 1.00e-34 142.00
IUUC-Tur-126483 Triticum urartu 42.89 2.00e-89 324.00
IUUC-Tme-127202 Tuber melanosporum 31.11 1.00e-54 208.00
IUUC-Tbe-127350 Tupaia belangeri 83.41 0.00e+00 645.00
IUUC-Ttr-129077 Tursiops truncatus 92.23 0.00e+00 1802.00
IUUC-Uma-129465 Ustilago maydis 35.89 2.00e-77 284.00
IUUC-Vda-129844 Verticillium dahliae 34.70 4.00e-63 236.00
IUUC-Vvi-131397 Vitis vinifera 37.05 1.00e-88 321.00
IUUC-Xtr-132057 Xenopus tropicalis 75.20 0.00e+00 1415.00
IUUC-Xma-134139 Xiphophorus maculatus 67.86 0.00e+00 799.00
IUUC-Yli-134424 Yarrowia lipolytica 32.20 7.00e-64 239.00
IUUC-Zma-135839 Zea mays 37.02 1.00e-88 321.00
Created Date 25-Jun-2017

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