iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019334

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01115411

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000007336.1	ENSCJAT00000014521.1	ENSCJAP00000013783.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-39	132.0	639	671
UBD/Beta-Prp	6.10e-65	220.3	57	261

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt+++t++a+   +d++lvs+s+Dgt +vWD+
   Q: 639  GHTAKITSVAWsphHDGRLVSASYDGTAQVWDT 671
           8***********8766****************7 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t + v     h++++ +l++sp  +d +vsG++  ++ ++ l+ +   
   Q: 57   IGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPrVKDLIVSGDEKGVVFCYWLNRNDSQ 145
           7899**************965677***************************************666**************966666666 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls.........fdsng............... 192
           +  l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s++         +   +               
   Q: 146  H--LFIEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVIHRLRG-HDDEIHSIAwcplpgedcL---Sinqeetsedpeitng 228
           5..899999999999999999*****************999********9.*********6666666662...0444668888999999 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgec 214
                       +l++gs+d+tv++w++++g+ 
   Q: 229  nalaqvpvtigCYLATGSKDQTVRIWSCSRGRA 261
           99***************************9976 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCARCS DAVPGGLFGF AARTSVFLVR VGPDAGESPG TPPFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKT VVTEHALHQH TISTLHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCTGCTTC TCTTGGCTCC GACGACCTGT AATTATGGGG CAGGAGCCGC GGACGCTGCC 60
GCCCTCTCCC AACTGGTACT GCGCCCGCTG CAGCGATGCT GTGCCCGGGG GCCTCTTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	87.99	0.00e+00	2597.00
IUUC-Apl-003586	Anas platyrhynchos	60.95	0.00e+00	1591.00
IUUC-Aca-004956	Anolis carolinensis	61.85	0.00e+00	1847.00
IUUC-Ame-010753	Astyanax mexicanus	50.33	0.00e+00	1481.00
IUUC-Bta-012315	Bos taurus	86.34	0.00e+00	2590.00
IUUC-Cfa-021254	Canis familiaris	87.70	0.00e+00	2660.00
IUUC-Cpo-021984	Cavia porcellus	81.50	0.00e+00	2345.00
IUUC-Csa-023650	Chlorocebus sabaeus	94.39	0.00e+00	2827.00
IUUC-Cho-024860	Choloepus hoffmanni	81.72	0.00e+00	2378.00
IUUC-Cin-025778	Ciona intestinalis	40.99	2.00e-160	560.00
IUUC-Csv-026313	Ciona savignyi	40.37	3.00e-162	565.00
IUUC-Dre-028096	Danio rerio	62.72	0.00e+00	1004.00
IUUC-Dno-029799	Dasypus novemcinctus	88.78	0.00e+00	2238.00
IUUC-Dor-030885	Dipodomys ordii	74.04	0.00e+00	1089.00
IUUC-Ete-032918	Echinops telfairi	79.95	0.00e+00	2389.00
IUUC-Eca-034144	Equus caballus	86.86	0.00e+00	2536.00
IUUC-Eeu-034843	Erinaceus europaeus	78.30	0.00e+00	1767.00
IUUC-Fca-035948	Felis catus	87.91	0.00e+00	2608.00
IUUC-Fal-037303	Ficedula albicollis	61.61	0.00e+00	1762.00
IUUC-Gmo-039591	Gadus morhua	52.19	0.00e+00	830.00
IUUC-Gga-040570	Gallus gallus	61.20	0.00e+00	1621.00
IUUC-Gac-042646	Gasterosteus aculeatus	47.86	0.00e+00	1348.00
IUUC-Ggo-045605	Gorilla gorilla	84.21	0.00e+00	1958.00
IUUC-Hsa-046122	Homo sapiens	95.49	0.00e+00	2832.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	90.73	0.00e+00	2312.00
IUUC-Lch-050489	Latimeria chalumnae	55.05	0.00e+00	635.00
IUUC-Loc-052259	Lepisosteus oculatus	60.22	0.00e+00	970.00
IUUC-Laf-053338	Loxodonta africana	86.52	0.00e+00	2593.00
IUUC-Mcc-055442	Macaca mulatta	94.59	0.00e+00	2833.00
IUUC-Meu-056245	Macropus eugenii	80.41	0.00e+00	848.00
IUUC-Mga-060202	Meleagris gallopavo	61.95	0.00e+00	1674.00
IUUC-Mmr-061730	Microcebus murinus	88.88	0.00e+00	2642.00
IUUC-Mdo-062880	Monodelphis domestica	73.07	0.00e+00	2179.00
IUUC-Mmu-063930	Mus musculus	81.12	0.00e+00	2301.00
IUUC-Mpu-066605	Mustela putorius furo	87.19	0.00e+00	2609.00
IUUC-Mlu-067765	Myotis lucifugus	87.41	0.00e+00	2628.00
IUUC-Nle-069183	Nomascus leucogenys	94.77	0.00e+00	2794.00
IUUC-Opr-070659	Ochotona princeps	76.63	0.00e+00	1177.00
IUUC-Ont-072356	Oreochromis niloticus	61.87	0.00e+00	1001.00
IUUC-Oan-073056	Ornithorhynchus anatinus	70.72	0.00e+00	1983.00
IUUC-Ocu-073881	Oryctolagus cuniculus	87.54	0.00e+00	2646.00
IUUC-Ola-087120	Oryzias latipes	57.00	1.00e-66	245.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.52	4.00e-30	127.00
IUUC-Oga-088343	Otolemur garnettii	88.95	0.00e+00	2650.00
IUUC-Oar-089257	Ovis aries	86.98	0.00e+00	2620.00
IUUC-Ptr-090497	Pan troglodytes	95.23	0.00e+00	2801.00
IUUC-Pan-092638	Papio anubis	94.33	0.00e+00	2816.00
IUUC-Psi-093096	Pelodiscus sinensis	63.76	0.00e+00	1607.00
IUUC-Pma-094571	Petromyzon marinus	41.65	4.00e-83	301.00
IUUC-Pfo-096742	Poecilia formosa	48.68	0.00e+00	1372.00
IUUC-Pab-098153	Pongo abelii	94.83	0.00e+00	2860.00
IUUC-Pca-100957	Procavia capensis	80.15	0.00e+00	2370.00
IUUC-Pva-102439	Pteropus vampyrus	88.49	0.00e+00	2654.00
IUUC-Rno-105891	Rattus norvegicus	80.82	0.00e+00	2288.00
IUUC-Sha-107181	Sarcophilus harrisii	73.15	0.00e+00	2067.00
IUUC-Ssc-115413	Sus scrofa	86.81	0.00e+00	2647.00
IUUC-Tgu-117082	Taeniopygia guttata	62.31	0.00e+00	1759.00
IUUC-Tru-118491	Takifugu rubripes	58.80	0.00e+00	942.00
IUUC-Tsy-119629	Tarsius syrichta	92.44	8.00e-164	572.00
IUUC-Tni-120240	Tetraodon nigroviridis	59.73	0.00e+00	953.00
IUUC-Tbe-127673	Tupaia belangeri	78.23	0.00e+00	2159.00
IUUC-Ttr-128562	Tursiops truncatus	84.33	0.00e+00	2525.00
IUUC-Vpa-130596	Vicugna pacos	84.15	0.00e+00	1855.00
IUUC-Xtr-132469	Xenopus tropicalis	55.76	0.00e+00	1631.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence