iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037303

Ensembl Protein ID

ENSFALP00000008710.1

UniProt Accession

U3K106; U3K106_FICAL

Genbank Protein ID

ENSFALP00000008710

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010809

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008360.1	ENSFALT00000008748.1	ENSFALP00000008710.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-36	121.6	634	671
UBD/Beta-Prp	1.40e-62	211.3	48	261

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvl 35
           gHt+++t+l++  +  ++lvs+++Dgt +vWD+ +  +
   Q: 634  GHTAKITSLSWspHHeGRLVSACYDGTAQVWDVMKEEP 671
           8***********733699**************977665 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqc 128
           +  +l gh++ ++  +f +      + +++s+D+ +k+wd  t + v  ++ h++ + +l++sp  +d +vsG++  +i ++ +++++ 
   Q: 48   FYGELIGHTDRISGFTFCHCPGqsgLCASSSDDGSVKIWDSGTLSAVLEYSLHQNPISALHWSPlVKDLIVSGDEKGVIVCY-WHNRSD 135
           4678889999988888766433345***************************************888**************8.788888 PP
   S: 129  leetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...............fdsng........ 192
           ++  + ++ ++v c++ +p + nl++ G +D++v + d+ +  +++++l+g h+d +++l+                            
   Q: 136  SQ-QFFPEPRTVFCLTCSPHNeNLVAIGYKDGMVVIIDIsRKREVVHRLRG-HEDEIHCLAwcpvpgeerlpawqdE---Lqapseegk 219
           87.7888888999999999999*****************78889******9.*********8877777777774440...255555556 PP
   S: 193  ...............kelvsgsldgtvklwdlqtgecvrtln 219
                           +l+sgs+d+t+++w++ +g+ v+tl+
   Q: 220  vpngeltqdtatkkgCYLASGSKDQTIRIWSCTRGRSVMTLK 261
           666666666677777999999999999999999999999986 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGVRALPASP NWYSSRCSDA SSDGRLFGFA ARHRVCLLDV AAAAAPTFYG ELIGHTDRIS 60
GFTFCHCPGQ SGLCASSSDD GSVKIWDSGT LSAVLEYSLH QNPISALHWS PLVKDLIVSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGGGACG GGTTCGGGGA TGGGGGTGCG GGCGCTGCCC GCCTCCCCCA ACTGGTACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

KEGG

fab:101820085

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	61.69	0.00e+00	1803.00
IUUC-Apl-003586	Anas platyrhynchos	84.23	0.00e+00	2306.00
IUUC-Aca-004956	Anolis carolinensis	65.14	0.00e+00	1974.00
IUUC-Ame-010753	Astyanax mexicanus	64.25	0.00e+00	1007.00
IUUC-Bta-012315	Bos taurus	61.98	0.00e+00	1820.00
IUUC-Cja-019334	Callithrix jacchus	61.55	0.00e+00	1808.00
IUUC-Cfa-021254	Canis familiaris	61.77	0.00e+00	1846.00
IUUC-Cpo-021984	Cavia porcellus	59.39	0.00e+00	1707.00
IUUC-Csa-023650	Chlorocebus sabaeus	62.09	0.00e+00	1801.00
IUUC-Cho-024860	Choloepus hoffmanni	57.88	0.00e+00	1632.00
IUUC-Cin-025778	Ciona intestinalis	40.91	2.00e-152	533.00
IUUC-Csv-026313	Ciona savignyi	40.61	1.00e-158	553.00
IUUC-Dre-028096	Danio rerio	56.13	0.00e+00	1413.00
IUUC-Dno-029799	Dasypus novemcinctus	65.45	0.00e+00	1642.00
IUUC-Dor-030885	Dipodomys ordii	55.30	2.00e-125	444.00
IUUC-Ete-032918	Echinops telfairi	58.79	0.00e+00	1701.00
IUUC-Eca-034144	Equus caballus	60.97	0.00e+00	1792.00
IUUC-Eeu-034843	Erinaceus europaeus	59.67	0.00e+00	1326.00
IUUC-Fca-035948	Felis catus	61.28	0.00e+00	1801.00
IUUC-Gmo-039591	Gadus morhua	54.15	0.00e+00	828.00
IUUC-Gga-040570	Gallus gallus	84.45	0.00e+00	2312.00
IUUC-Gac-042646	Gasterosteus aculeatus	51.82	0.00e+00	1305.00
IUUC-Ggo-045605	Gorilla gorilla	59.32	0.00e+00	1336.00
IUUC-Hsa-046122	Homo sapiens	60.97	0.00e+00	1804.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	65.75	0.00e+00	1642.00
IUUC-Lch-050489	Latimeria chalumnae	57.01	0.00e+00	650.00
IUUC-Loc-052259	Lepisosteus oculatus	63.06	0.00e+00	966.00
IUUC-Laf-053338	Loxodonta africana	61.83	0.00e+00	1799.00
IUUC-Mcc-055442	Macaca mulatta	61.99	0.00e+00	1800.00
IUUC-Meu-056245	Macropus eugenii	70.62	0.00e+00	717.00
IUUC-Mga-060202	Meleagris gallopavo	82.52	0.00e+00	2352.00
IUUC-Mmr-061730	Microcebus murinus	60.49	0.00e+00	1773.00
IUUC-Mdo-062880	Monodelphis domestica	64.05	0.00e+00	1905.00
IUUC-Mmu-063930	Mus musculus	60.63	0.00e+00	1720.00
IUUC-Mpu-066605	Mustela putorius furo	61.04	0.00e+00	1813.00
IUUC-Mlu-067765	Myotis lucifugus	61.32	0.00e+00	1828.00
IUUC-Nle-069183	Nomascus leucogenys	61.14	0.00e+00	1751.00
IUUC-Opr-070659	Ochotona princeps	51.58	0.00e+00	746.00
IUUC-Ont-072356	Oreochromis niloticus	48.89	0.00e+00	1411.00
IUUC-Oan-073056	Ornithorhynchus anatinus	64.73	0.00e+00	1842.00
IUUC-Ocu-073881	Oryctolagus cuniculus	61.87	0.00e+00	1867.00
IUUC-Ola-087120	Oryzias latipes	60.78	9.00e-69	252.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.28	8.00e-33	135.00
IUUC-Oga-088343	Otolemur garnettii	61.95	0.00e+00	1823.00
IUUC-Oar-089257	Ovis aries	62.25	0.00e+00	1843.00
IUUC-Ptr-090497	Pan troglodytes	60.71	0.00e+00	1795.00
IUUC-Pan-092638	Papio anubis	61.18	0.00e+00	1793.00
IUUC-Psi-093096	Pelodiscus sinensis	72.96	0.00e+00	1888.00
IUUC-Pma-094571	Petromyzon marinus	54.69	1.00e-65	243.00
IUUC-Pfo-096348	Poecilia formosa	49.03	0.00e+00	1344.00
IUUC-Pab-098153	Pongo abelii	61.04	0.00e+00	1804.00
IUUC-Pca-100957	Procavia capensis	59.32	0.00e+00	1687.00
IUUC-Pva-102439	Pteropus vampyrus	61.44	0.00e+00	1847.00
IUUC-Rno-105891	Rattus norvegicus	60.10	0.00e+00	1689.00
IUUC-Sha-107181	Sarcophilus harrisii	65.52	0.00e+00	1865.00
IUUC-Ssc-115413	Sus scrofa	61.42	0.00e+00	1827.00
IUUC-Tgu-117082	Taeniopygia guttata	92.53	0.00e+00	2700.00
IUUC-Tru-118491	Takifugu rubripes	60.25	0.00e+00	939.00
IUUC-Tsy-119629	Tarsius syrichta	69.18	3.00e-121	430.00
IUUC-Tni-120240	Tetraodon nigroviridis	61.04	0.00e+00	941.00
IUUC-Tbe-127673	Tupaia belangeri	54.74	0.00e+00	1469.00
IUUC-Ttr-128562	Tursiops truncatus	60.14	0.00e+00	1737.00
IUUC-Vpa-130596	Vicugna pacos	63.84	0.00e+00	1385.00
IUUC-Xtr-132469	Xenopus tropicalis	55.93	0.00e+00	1642.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence