iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089257

Ensembl Protein ID

ENSOARP00000010949.1

UniProt Accession

W5PKH7; W5PKH7_SHEEP

Genbank Protein ID

ENSOARP00000010949

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01093654

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010195.1	ENSOART00000011107.1	ENSOARP00000010949.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.80e-42	139.5	636	671
UBD/Beta-Prp	1.20e-65	221.8	57	266

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           gHt+++t+la+   +d++lvs+s+Dgt +vWD+ + 
   Q: 636  GHTAKITSLAWsphHDGRLVSASYDGTAQVWDTLQE 671
           8***********8766****************7665 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh+++v+  +f ++     + +t+s+D+t+k+w++++ + v     h++++ +l++sp  +d +vsG++  ++ ++ l+ +   
   Q: 57   IGELVGHTEKVSGFTFCHHPGqynLCATSSDDGTVKIWEVEAKTVVTEHALHQHTISALHWSPrVKDLIVSGDEKGVVFCYWLNRNDSQ 145
           78999*********9988754577***************************************666**************966666666 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfdsng........................ 192
           +  l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s+++ + +                        
   Q: 146  H--LFIEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVMHRLRG-HDDEIHSIAWCPLSgedclsinqeenseepeipngkvt 231
           5..899999999999999999*****************999********9.*********66666666777777888999999999999 PP
   S: 193  ........kelvsgsldgtvklwdlqtgecvrtln 219
                    +l++gs+d+t+++w++++g+ v+tl+
   Q: 232  aqtpltkgCYLATGSKDQTIRIWSCSRGRGVMTLK 266
           999***99********************9999875 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCSRCS DAVPGGLFGF AARTSVFLVR VGPGADTIPG TPPFRVIGEL 60
VGHTEKVSGF TFCHHPGQYN LCATSSDDGT VKIWEVEAKT VVTEHALHQH TISALHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGACAGG AACCGCGCAC GTTGCCGCCC TCCCCTAACT GGTACTGCTC CCGATGCAGC 60
GATGCCGTGC CCGGGGGCCT CTTCGGCTTC GCGGCGCGGA CTTCGGTCTT CCTTGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	89.49	0.00e+00	2645.00
IUUC-Apl-003586	Anas platyrhynchos	63.10	0.00e+00	1647.00
IUUC-Aca-004956	Anolis carolinensis	61.88	0.00e+00	1868.00
IUUC-Ame-010753	Astyanax mexicanus	62.79	0.00e+00	1002.00
IUUC-Bta-012315	Bos taurus	96.83	0.00e+00	2888.00
IUUC-Cja-019334	Callithrix jacchus	86.98	0.00e+00	2654.00
IUUC-Cfa-021254	Canis familiaris	89.29	0.00e+00	2708.00
IUUC-Cpo-021984	Cavia porcellus	80.68	0.00e+00	2323.00
IUUC-Csa-023650	Chlorocebus sabaeus	87.20	0.00e+00	2618.00
IUUC-Cho-024860	Choloepus hoffmanni	82.00	0.00e+00	2401.00
IUUC-Cin-025778	Ciona intestinalis	41.17	2.00e-158	553.00
IUUC-Csv-026313	Ciona savignyi	40.66	4.00e-164	571.00
IUUC-Dre-028096	Danio rerio	63.59	0.00e+00	1013.00
IUUC-Dno-029799	Dasypus novemcinctus	88.24	0.00e+00	2223.00
IUUC-Dor-030885	Dipodomys ordii	75.00	0.00e+00	1095.00
IUUC-Ete-032918	Echinops telfairi	80.35	0.00e+00	2399.00
IUUC-Eca-034144	Equus caballus	88.73	0.00e+00	2584.00
IUUC-Eeu-034843	Erinaceus europaeus	78.49	0.00e+00	1789.00
IUUC-Fca-035948	Felis catus	88.90	0.00e+00	2645.00
IUUC-Fal-037303	Ficedula albicollis	61.85	0.00e+00	1819.00
IUUC-Gmo-039591	Gadus morhua	53.85	0.00e+00	850.00
IUUC-Gga-040570	Gallus gallus	62.97	0.00e+00	1644.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.39	0.00e+00	1353.00
IUUC-Ggo-045605	Gorilla gorilla	80.78	0.00e+00	1833.00
IUUC-Hsa-046122	Homo sapiens	87.88	0.00e+00	2605.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	89.66	0.00e+00	2283.00
IUUC-Lch-050489	Latimeria chalumnae	49.11	0.00e+00	867.00
IUUC-Loc-052259	Lepisosteus oculatus	60.88	0.00e+00	978.00
IUUC-Laf-053338	Loxodonta africana	87.28	0.00e+00	2592.00
IUUC-Mcc-055442	Macaca mulatta	87.34	0.00e+00	2619.00
IUUC-Meu-056245	Macropus eugenii	83.37	0.00e+00	872.00
IUUC-Mga-060202	Meleagris gallopavo	63.30	0.00e+00	1712.00
IUUC-Mmr-061730	Microcebus murinus	87.10	0.00e+00	2608.00
IUUC-Mdo-062880	Monodelphis domestica	73.73	0.00e+00	2211.00
IUUC-Mmu-063930	Mus musculus	80.54	0.00e+00	2303.00
IUUC-Mpu-066605	Mustela putorius furo	88.38	0.00e+00	2649.00
IUUC-Mlu-067765	Myotis lucifugus	88.93	0.00e+00	2694.00
IUUC-Nle-069183	Nomascus leucogenys	87.43	0.00e+00	2576.00
IUUC-Opr-070659	Ochotona princeps	76.37	0.00e+00	1182.00
IUUC-Ont-072356	Oreochromis niloticus	62.07	0.00e+00	1014.00
IUUC-Oan-073056	Ornithorhynchus anatinus	71.81	0.00e+00	2005.00
IUUC-Ocu-073881	Oryctolagus cuniculus	86.88	0.00e+00	2640.00
IUUC-Ola-087120	Oryzias latipes	58.94	4.00e-69	253.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.80	2.00e-31	131.00
IUUC-Oga-088343	Otolemur garnettii	87.43	0.00e+00	2625.00
IUUC-Ptr-090497	Pan troglodytes	87.75	0.00e+00	2579.00
IUUC-Pan-092638	Papio anubis	87.15	0.00e+00	2609.00
IUUC-Psi-093096	Pelodiscus sinensis	65.62	0.00e+00	1650.00
IUUC-Pma-094571	Petromyzon marinus	43.28	4.00e-85	308.00
IUUC-Pfo-096742	Poecilia formosa	48.94	0.00e+00	1389.00
IUUC-Pab-098153	Pongo abelii	87.22	0.00e+00	2643.00
IUUC-Pca-100957	Procavia capensis	80.65	0.00e+00	2390.00
IUUC-Pva-102439	Pteropus vampyrus	90.34	0.00e+00	2712.00
IUUC-Rno-105891	Rattus norvegicus	80.77	0.00e+00	2292.00
IUUC-Sha-107181	Sarcophilus harrisii	73.87	0.00e+00	2090.00
IUUC-Ssc-115413	Sus scrofa	91.61	0.00e+00	2784.00
IUUC-Tgu-117082	Taeniopygia guttata	62.90	0.00e+00	1786.00
IUUC-Tru-118491	Takifugu rubripes	60.00	0.00e+00	958.00
IUUC-Tsy-119629	Tarsius syrichta	93.77	5.00e-168	585.00
IUUC-Tni-120240	Tetraodon nigroviridis	60.22	0.00e+00	966.00
IUUC-Tbe-127673	Tupaia belangeri	76.69	0.00e+00	2108.00
IUUC-Ttr-128562	Tursiops truncatus	90.22	0.00e+00	2702.00
IUUC-Vpa-130596	Vicugna pacos	86.67	0.00e+00	1896.00
IUUC-Xtr-132469	Xenopus tropicalis	55.92	0.00e+00	1622.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence