iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004424

UUCD1 version

UUC-AnC-00327

Ensembl Protein ID

ENSACAP00000000582.2

UniProt Accession

H9G408; H9G408_ANOCA

Protein Name

Uncharacterized protein

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000000378.3	ENSACAT00000000601.3	ENSACAP00000000582.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-12	45.3	1107	1137

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
            + +t++   d t+ l+sG+ Dg i +WD+ tg
   Q: 1107 GA-ITAVYI-DqTMaLASGGQDGAICLWDVLTG 1137
           55.889977.446659*************9887 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MTLTDRLREK ISGAFHKHGL LCASFPIPII LFTGLCVLAC CYPLLKLPLP GTGPVEYTTP 60
AKDYVPPPAF STHQQGEPNE RPDWYTGAPV AYIQQVLVKA TVSPWPTTFL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTGTGTCC TGCTGCGAAG TGCCCCTGAT GCTGGACTCT GCTGCAGCCC TGCTGAGGCT 60
TCCCGGGATG GCAGCAAGTT GATGGGTGGC TGAGGATGAC ATTGACTGAC AGGCTGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	76.50	0.00e+00	867.00
IUUC-Apl-003294	Anas platyrhynchos	76.13	0.00e+00	1726.00
IUUC-Bta-013478	Bos taurus	69.71	0.00e+00	1494.00
IUUC-Cel-018160	Caenorhabditis elegans	25.00	8.00e-71	262.00
IUUC-Cja-019123	Callithrix jacchus	67.95	0.00e+00	1460.00
IUUC-Cfa-021082	Canis familiaris	69.64	0.00e+00	1462.00
IUUC-Cpo-022477	Cavia porcellus	66.98	0.00e+00	1435.00
IUUC-Csa-023176	Chlorocebus sabaeus	68.64	0.00e+00	1484.00
IUUC-Cin-025490	Ciona intestinalis	31.15	6.00e-120	425.00
IUUC-Csv-026115	Ciona savignyi	37.24	2.00e-130	460.00
IUUC-Dre-028008	Danio rerio	63.95	0.00e+00	1407.00
IUUC-Dno-028887	Dasypus novemcinctus	73.19	0.00e+00	944.00
IUUC-Dor-030467	Dipodomys ordii	78.16	0.00e+00	725.00
IUUC-Dme-032087	Drosophila melanogaster	30.88	1.00e-104	374.00
IUUC-Ete-032372	Echinops telfairi	58.86	0.00e+00	843.00
IUUC-Eca-033896	Equus caballus	70.26	0.00e+00	1584.00
IUUC-Eeu-035099	Erinaceus europaeus	68.27	0.00e+00	923.00
IUUC-Fca-035616	Felis catus	66.10	0.00e+00	1407.00
IUUC-Fal-037231	Ficedula albicollis	72.37	0.00e+00	1618.00
IUUC-Gmo-039439	Gadus morhua	63.28	0.00e+00	868.00
IUUC-Gac-041516	Gasterosteus aculeatus	63.21	0.00e+00	1383.00
IUUC-Hsa-046674	Homo sapiens	70.39	0.00e+00	1546.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	69.74	0.00e+00	1545.00
IUUC-Lch-049689	Latimeria chalumnae	67.64	0.00e+00	1570.00
IUUC-Loc-052417	Lepisosteus oculatus	52.99	4.00e-134	471.00
IUUC-Laf-053795	Loxodonta africana	68.26	0.00e+00	1498.00
IUUC-Mcc-055502	Macaca mulatta	69.79	0.00e+00	1539.00
IUUC-Mga-059805	Meleagris gallopavo	76.50	0.00e+00	1731.00
IUUC-Mmr-060997	Microcebus murinus	69.74	0.00e+00	1562.00
IUUC-Mdo-062940	Monodelphis domestica	69.05	0.00e+00	1521.00
IUUC-Mmu-063255	Mus musculus	69.51	0.00e+00	1528.00
IUUC-Mpu-066158	Mustela putorius furo	69.82	0.00e+00	1529.00
IUUC-Mlu-067201	Myotis lucifugus	67.92	0.00e+00	1477.00
IUUC-Nle-069145	Nomascus leucogenys	69.84	0.00e+00	1028.00
IUUC-Opr-070797	Ochotona princeps	65.33	0.00e+00	1382.00
IUUC-Ont-071553	Oreochromis niloticus	63.22	0.00e+00	1404.00
IUUC-Ocu-074598	Oryctolagus cuniculus	69.61	0.00e+00	1502.00
IUUC-Ola-086650	Oryzias latipes	79.73	2.00e-100	357.00
IUUC-Oar-089287	Ovis aries	68.27	0.00e+00	868.00
IUUC-Pan-092004	Papio anubis	70.19	0.00e+00	1525.00
IUUC-Psi-093028	Pelodiscus sinensis	71.81	0.00e+00	1539.00
IUUC-Pma-094145	Petromyzon marinus	47.35	0.00e+00	993.00
IUUC-Pfo-096320	Poecilia formosa	62.90	0.00e+00	1408.00
IUUC-Pab-097862	Pongo abelii	70.39	0.00e+00	1545.00
IUUC-Pca-100862	Procavia capensis	58.46	0.00e+00	1130.00
IUUC-Pva-103050	Pteropus vampyrus	74.30	0.00e+00	1024.00
IUUC-Rno-105852	Rattus norvegicus	69.84	0.00e+00	1535.00
IUUC-Sha-107312	Sarcophilus harrisii	69.18	0.00e+00	1536.00
IUUC-Sar-113311	Sorex araneus	60.95	2.00e-155	543.00
IUUC-Ssc-116356	Sus scrofa	69.84	0.00e+00	1551.00
IUUC-Tgu-116896	Taeniopygia guttata	61.34	3.00e-165	575.00
IUUC-Tru-118197	Takifugu rubripes	61.92	0.00e+00	1382.00
IUUC-Tni-119823	Tetraodon nigroviridis	61.88	0.00e+00	1367.00
IUUC-Ttr-129164	Tursiops truncatus	69.64	0.00e+00	1506.00
IUUC-Xtr-132819	Xenopus tropicalis	65.50	0.00e+00	1528.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence