iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003199

Ensembl Protein ID

ENSAPLP00000014587.1

UniProt Accession

U3J510; U3J510_ANAPL

Genbank Protein ID

ENSAPLP00000014587

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01007733

Gene Name

UBE2D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000014740.1	ENSAPLT00000015366.1	ENSAPLP00000014587.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.90e-55	184.8	1	131
UBD/UBC-like/UBD_UBC	2.80e-83	276.6	1	134

Active Site

Position(s)	Description	Evidence
77	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 5    elkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWs 93
           el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Ws
   Q: 1    ELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWS 86
           799*****************.9************************************************************9..**** PP
   S: 94   palsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           pal++++vllsi+sll++pnp++pl  e+a+++k++re+y++++r
   Q: 87   PALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAR 131
           *****************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 5    elkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaal 93
           el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+al
   Q: 1    ELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPAL 89
           89*************************************************************************************** PP
   S: 94   tlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           t+skvlls+csll+d++pddplv+eiariyktd+eky+riarewt
   Q: 90   TISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWT 134
           ********************************************8 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

ELNDLARDPP AQCSAGPVGD DMFHWQATIM GPNDSPYQGG VFFLTIHFPT DYPFKPPKVA 60
FTTRIYHPNI NSNGSICLDI LRSQWSPALT ISKVLLSICS LLCDPNPDDP LVPEIARIYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTTGAATG ATCTGGCACG TGATCCTCCA GCACAGTGTT CAGCAGGGCC GGTTGGTGAT 60
GACAGTAAGT ATGCTGCTGT TTGGCAAACA CTCGCAGTCT CTACCTTTTT TTTGCTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0043234--C:protein complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001778	Ailuropoda melanoleuca	100.00	6.00e-81	291.00
IUUC-Aca-005236	Anolis carolinensis	100.00	3.00e-81	293.00
IUUC-Bta-013158	Bos taurus	100.00	3.00e-81	293.00
IUUC-Cja-019886	Callithrix jacchus	100.00	3.00e-81	293.00
IUUC-Cfa-020436	Canis familiaris	100.00	3.00e-81	293.00
IUUC-Dno-028952	Dasypus novemcinctus	100.00	4.00e-81	292.00
IUUC-Ete-032295	Echinops telfairi	100.00	4.00e-81	292.00
IUUC-Eca-033293	Equus caballus	100.00	2.00e-81	293.00
IUUC-Gga-040758	Gallus gallus	100.00	3.00e-81	293.00
IUUC-Ggo-045375	Gorilla gorilla	100.00	3.00e-81	293.00
IUUC-Hsa-045885	Homo sapiens	100.00	3.00e-81	293.00
IUUC-Hvu-047546	Hordeum vulgare	78.42	3.00e-66	243.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	100.00	2.00e-81	293.00
IUUC-Lch-050583	Latimeria chalumnae	92.03	3.00e-73	266.00
IUUC-Laf-053580	Loxodonta africana	100.00	5.00e-81	292.00
IUUC-Mcc-054673	Macaca mulatta	100.00	3.00e-81	293.00
IUUC-Mmr-061474	Microcebus murinus	100.00	4.00e-81	292.00
IUUC-Mdo-062962	Monodelphis domestica	100.00	3.00e-81	293.00
IUUC-Mmu-063518	Mus musculus	100.00	3.00e-81	293.00
IUUC-Mpu-066604	Mustela putorius furo	100.00	2.00e-81	293.00
IUUC-Nle-069800	Nomascus leucogenys	98.56	3.00e-78	283.00
IUUC-Ont-071766	Oreochromis niloticus	98.56	3.00e-80	290.00
IUUC-Ocu-074315	Oryctolagus cuniculus	100.00	3.00e-81	293.00
IUUC-Ola-086331	Oryzias latipes	98.56	3.00e-80	290.00
IUUC-Ptr-090707	Pan troglodytes	100.00	3.00e-81	293.00
IUUC-Pan-092143	Papio anubis	100.00	3.00e-81	293.00
IUUC-Pfo-096753	Poecilia formosa	98.56	3.00e-80	290.00
IUUC-Pab-097764	Pongo abelii	100.00	3.00e-81	293.00
IUUC-Ptt-103723	Puccinia triticina	78.42	3.00e-61	226.00
IUUC-Sar-113302	Sorex araneus	100.00	4.00e-81	292.00
IUUC-Tru-118272	Takifugu rubripes	98.56	6.00e-80	288.00
IUUC-Tsy-119491	Tarsius syrichta	97.12	2.00e-76	278.00
IUUC-Tni-120056	Tetraodon nigroviridis	98.56	6.00e-80	288.00
IUUC-Tbe-127609	Tupaia belangeri	100.00	2.00e-67	246.00
IUUC-Vpa-130446	Vicugna pacos	99.28	1.00e-79	289.00
IUUC-Xtr-132329	Xenopus tropicalis	100.00	3.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence