iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000020226.3	ENSMMUT00000028454.3	ENSMMUP00000026628.3
ENSMMUG00000020226.3	ENSMMUT00000028455.3	ENSMMUP00000026629.2
ENSMMUG00000020226.3	ENSMMUT00000067115.1	ENSMMUP00000048376.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.60e-16	59.9	229	274
E3 adaptor/Cullin RING/DCX/DWD	3.10e-29	100.8	23	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           +++w ++++++SLqhLCR++Irr +++q++   ++LP P++L ++L+y+
   Q: 229  VYFWATPRQVPSLQHLCRMSIRRVMPTQEV---QELPVPSKLLEFLSYR 274
           689************************999...**************97 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Ht+ v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 23   HTEVVRDLTFaPDgsLILVSASRDKTLRVWDLKDD 57
           9**********8865668*************9987 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MASFPPRVNE KEIGKLLLNL VDHTEVVRDL TFAPDGSLIL VSASRDKTLR VWDLKDDGNM 60
MKVLRGHQNW VYSCAFSPDS SMLCSVGASK AVFLWNMDKY TMIRKLEGHH HDVVACDFSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTATCTCC CGCGCCGCCC GCCATTTTGA TTTCAGTGTC TCGTTTGCGG TCGGCAGCGT 60
TGGGGGAACT GACTTGTTCC GCAGGCGCGA GGCTGGGTAC AGGGTCTATT GTCTGTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	97.33	2.00e-153	535.00
IUUC-Apl-003903	Anas platyrhynchos	89.69	1.00e-142	499.00
IUUC-Aca-005214	Anolis carolinensis	73.58	1.00e-117	416.00
IUUC-Ame-011740	Astyanax mexicanus	75.00	7.00e-124	437.00
IUUC-Bta-013475	Bos taurus	98.09	8.00e-154	536.00
IUUC-Cja-019053	Callithrix jacchus	99.62	4.00e-155	540.00
IUUC-Cfa-020103	Canis familiaris	98.85	1.00e-155	542.00
IUUC-Cpo-022438	Cavia porcellus	96.56	3.00e-152	531.00
IUUC-Csa-024062	Chlorocebus sabaeus	100.00	2.00e-156	545.00
IUUC-Cho-024334	Choloepus hoffmanni	79.01	4.00e-116	411.00
IUUC-Cin-025590	Ciona intestinalis	42.59	6.00e-63	234.00
IUUC-Csv-026023	Ciona savignyi	45.19	5.00e-65	241.00
IUUC-Dre-028089	Danio rerio	77.01	2.00e-125	442.00
IUUC-Dno-029436	Dasypus novemcinctus	94.66	2.00e-149	522.00
IUUC-Dor-031107	Dipodomys ordii	94.58	2.00e-133	468.00
IUUC-Ete-032326	Echinops telfairi	94.23	7.00e-149	520.00
IUUC-Eca-033401	Equus caballus	97.33	2.00e-153	535.00
IUUC-Eeu-034520	Erinaceus europaeus	93.31	1.00e-151	529.00
IUUC-Fca-036386	Felis catus	98.47	2.00e-154	538.00
IUUC-Fal-036616	Ficedula albicollis	88.17	2.00e-140	492.00
IUUC-Gmo-039335	Gadus morhua	74.81	2.00e-120	425.00
IUUC-Gga-040856	Gallus gallus	89.31	1.00e-141	496.00
IUUC-Gac-042140	Gasterosteus aculeatus	75.95	4.00e-121	428.00
IUUC-Ggo-044619	Gorilla gorilla	98.47	3.00e-155	541.00
IUUC-Hsa-046300	Homo sapiens	99.24	5.00e-156	543.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	97.71	1.00e-153	536.00
IUUC-Lch-049550	Latimeria chalumnae	80.53	6.00e-130	456.00
IUUC-Loc-051769	Lepisosteus oculatus	77.78	1.00e-126	446.00
IUUC-Laf-054576	Loxodonta africana	96.56	3.00e-152	531.00
IUUC-Meu-055989	Macropus eugenii	91.09	3.00e-141	494.00
IUUC-Mga-059722	Meleagris gallopavo	89.31	4.00e-143	501.00
IUUC-Mmr-060970	Microcebus murinus	97.33	3.00e-153	534.00
IUUC-Mdo-062249	Monodelphis domestica	71.76	6.00e-104	370.00
IUUC-Mmu-063742	Mus musculus	93.49	2.00e-147	515.00
IUUC-Mpu-066518	Mustela putorius furo	96.56	7.00e-153	533.00
IUUC-Mlu-068063	Myotis lucifugus	96.95	3.00e-153	534.00
IUUC-Nle-069561	Nomascus leucogenys	98.85	1.00e-155	542.00
IUUC-Opr-071158	Ochotona princeps	91.57	7.00e-143	500.00
IUUC-Ont-072542	Oreochromis niloticus	75.19	2.00e-120	425.00
IUUC-Oan-073217	Ornithorhynchus anatinus	92.34	2.00e-146	511.00
IUUC-Ocu-074251	Oryctolagus cuniculus	96.95	6.00e-152	530.00
IUUC-Ola-086549	Oryzias latipes	76.34	3.00e-123	435.00
IUUC-Oga-088382	Otolemur garnettii	98.47	9.00e-155	539.00
IUUC-Oar-090263	Ovis aries	96.18	6.00e-149	520.00
IUUC-Ptr-090922	Pan troglodytes	98.47	2.00e-155	541.00
IUUC-Pan-092518	Papio anubis	100.00	2.00e-156	545.00
IUUC-Psi-093512	Pelodiscus sinensis	88.85	1.00e-143	502.00
IUUC-Pma-094324	Petromyzon marinus	62.82	2.00e-98	352.00
IUUC-Pfo-096264	Poecilia formosa	74.43	1.00e-120	426.00
IUUC-Pab-098018	Pongo abelii	99.24	1.00e-155	542.00
IUUC-Pca-101034	Procavia capensis	93.13	3.00e-143	501.00
IUUC-Pva-102862	Pteropus vampyrus	93.89	7.00e-144	503.00
IUUC-Rno-106116	Rattus norvegicus	93.13	6.00e-147	513.00
IUUC-Sha-106952	Sarcophilus harrisii	91.22	7.00e-143	500.00
IUUC-Sar-113211	Sorex araneus	75.00	7.00e-73	267.00
IUUC-Ssc-116440	Sus scrofa	98.09	3.00e-154	538.00
IUUC-Tgu-116675	Taeniopygia guttata	84.39	6.00e-137	480.00
IUUC-Tru-118295	Takifugu rubripes	76.34	4.00e-118	417.00
IUUC-Tsy-118916	Tarsius syrichta	77.10	1.00e-115	409.00
IUUC-Tni-120302	Tetraodon nigroviridis	74.81	1.00e-117	416.00
IUUC-Tbe-127416	Tupaia belangeri	82.44	3.00e-120	424.00
IUUC-Ttr-128185	Tursiops truncatus	98.09	1.00e-154	539.00
IUUC-Xtr-132465	Xenopus tropicalis	84.67	9.00e-136	476.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence