iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012339

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

VPS18 protein

Genbank Nucleotide ID

DAAA02028555

Gene Name

VPS18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000011567.4	ENSBTAT00000015368.4	ENSBTAP00000015368.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.80e-06	26.5	853	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp......CgHvfhadCl.qkw.pglknssskefr........................................ 41
           Ca+C  df   pl+++      CgH+fhadCl q++ pgl+  ++k++r                                        
   Q: 853  CATC--DF---PLLNRpfylflCGHMFHADCLlQAVrPGLP--AYKQARleelqrklgaapppakgsarakeaeggtaaggpsreqlka 934
           9***..99...66555666668*********9788887777..8888877777777777777777777788888888888888888888 PP
   S: 42   .........CPlC 45
                    C++C
   Q: 935  dldelvaaeCVYC 947
           8888888888887 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MASILDEYED SLSRSTVLQP GCPSVGIPHS GYVNAQLEKE APIFTKQRID FTPSERITSL 60
VVSCNQLCMS LGKDTLLRID LGKANEPNHM ELGRKDDAKV HKMFLDPTGS HLLIALSSTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCACCTGA GATCGGCTAA GGGGAACCGG TGCTCTCTTG GGGGCGTGAG TTGGGTGCAG 60
GACTGCGTCA AATAAAGGAG GCGAGCTCTC TGATCTTCTC GCTCTATAAG GCGAGAGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000547--Clathrin_H-chain/VPS_repeat
IPR007810--Pep3_Vps18
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50236--CHCR

Pfam

PF00637--Clathrin
PF05131--Pep3_Vps18

Gene Ontology

GO:0005884--C:actin filament
GO:0030123--C:AP-3 adaptor complex
GO:0033263--C:CORVET complex
GO:0005769--C:early endosome
GO:0005768--C:endosome
GO:0030897--C:HOPS complex
GO:0005770--C:late endosome
GO:0005765--C:lysosomal membrane
GO:0030674--F:protein binding, bridging
GO:0007032--P:endosome organization
GO:0008333--P:endosome to lysosome transport
GO:0006886--P:intracellular protein transport
GO:0007040--P:lysosome organization
GO:0035542--P:regulation of SNARE complex assembly
GO:0006904--P:vesicle docking involved in exocytosis
GO:0046718--P:viral entry into host cell

KEGG

bta:518781

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000419	Aegilops tauschii	31.90	7.00e-117	415.00
IUUC-Aml-001240	Ailuropoda melanoleuca	97.84	0.00e+00	1895.00
IUUC-Atr-003125	Amborella trichopoda	32.80	3.00e-132	466.00
IUUC-Apl-004181	Anas platyrhynchos	72.69	0.00e+00	1492.00
IUUC-Aca-004437	Anolis carolinensis	72.38	0.00e+00	1470.00
IUUC-Aly-006046	Arabidopsis lyrata	33.23	3.00e-142	499.00
IUUC-Ath-006932	Arabidopsis thaliana	33.30	1.00e-141	497.00
IUUC-Ago-007800	Ashbya gossypii	23.61	9.00e-62	231.00
IUUC-Acl-008035	Aspergillus clavatus	31.64	1.00e-117	417.00
IUUC-Afl-008714	Aspergillus flavus	31.42	4.00e-115	409.00
IUUC-Afu-009063	Aspergillus fumigatus	32.49	8.00e-120	424.00
IUUC-Ani-009384	Aspergillus nidulans	32.70	4.00e-122	432.00
IUUC-Ang-009507	Aspergillus niger	32.49	3.00e-118	419.00
IUUC-Aor-010094	Aspergillus oryzae	31.42	8.00e-115	408.00
IUUC-Ate-010421	Aspergillus terreus	31.48	6.00e-103	369.00
IUUC-Ame-011797	Astyanax mexicanus	65.75	0.00e+00	1342.00
IUUC-Bgr-012107	Blumeria graminis	31.54	6.00e-117	415.00
IUUC-Bci-013895	Botrytis cinerea	33.85	1.00e-126	447.00
IUUC-Bdi-014554	Brachypodium distachyon	34.42	1.00e-135	477.00
IUUC-Bol-015270	Brassica oleracea	33.61	1.00e-143	504.00
IUUC-Bra-017424	Brassica rapa	33.37	6.00e-140	491.00
IUUC-Cel-018455	Caenorhabditis elegans	26.25	5.00e-90	325.00
IUUC-Cja-019629	Callithrix jacchus	96.20	0.00e+00	1886.00
IUUC-Cfa-020425	Canis familiaris	97.74	0.00e+00	1888.00
IUUC-Cpo-021349	Cavia porcellus	96.00	0.00e+00	1853.00
IUUC-Cre-022799	Chlamydomonas reinhardtii	25.70	3.00e-31	130.00
IUUC-Csa-023559	Chlorocebus sabaeus	96.92	0.00e+00	1887.00
IUUC-Cho-024862	Choloepus hoffmanni	88.86	0.00e+00	1392.00
IUUC-Cin-025599	Ciona intestinalis	41.25	0.00e+00	628.00
IUUC-Csv-026152	Ciona savignyi	42.34	0.00e+00	788.00
IUUC-Cgl-026551	Colletotrichum gloeosporioides	32.90	3.00e-119	423.00
IUUC-Cne-026907	Cryptococcus neoformans	31.24	2.00e-120	427.00
IUUC-Dre-027747	Danio rerio	65.81	0.00e+00	1385.00
IUUC-Dno-029668	Dasypus novemcinctus	97.02	0.00e+00	1874.00
IUUC-Dor-030404	Dipodomys ordii	91.26	0.00e+00	1775.00
IUUC-Dse-031345	Dothistroma septosporum	33.70	1.00e-129	457.00
IUUC-Dme-031711	Drosophila melanogaster	34.65	1.00e-151	530.00
IUUC-Ete-032308	Echinops telfairi	92.66	0.00e+00	955.00
IUUC-Eca-033637	Equus caballus	98.05	0.00e+00	1911.00
IUUC-Eeu-035151	Erinaceus europaeus	96.63	0.00e+00	1404.00
IUUC-Fca-035585	Felis catus	97.74	0.00e+00	1883.00
IUUC-Fal-037122	Ficedula albicollis	72.10	0.00e+00	1482.00
IUUC-Fox-038030	Fusarium oxysporum	33.74	2.00e-128	453.00
IUUC-Fso-038426	Fusarium solani	33.84	6.00e-134	471.00
IUUC-Gmo-038784	Gadus morhua	66.63	0.00e+00	1349.00
IUUC-Ggr-039973	Gaeumannomyces graminis	34.12	1.00e-128	454.00
IUUC-Gga-040692	Gallus gallus	74.02	0.00e+00	1513.00
IUUC-Gac-041868	Gasterosteus aculeatus	65.82	0.00e+00	1343.00
IUUC-Gma-044274	Glycine max	34.39	7.00e-145	508.00
IUUC-Ggo-045053	Gorilla gorilla	96.92	0.00e+00	1875.00
IUUC-Hsa-046635	Homo sapiens	97.12	0.00e+00	1877.00
IUUC-Hvu-047361	Hordeum vulgare	33.91	1.00e-134	474.00
IUUC-Itr-048868	Ictidomys tridecemlineatus	97.33	0.00e+00	1874.00
IUUC-Kpa-049270	Komagataella pastoris	24.58	2.00e-77	283.00
IUUC-Lch-050188	Latimeria chalumnae	68.31	0.00e+00	1257.00
IUUC-Lpe-051026	Leersia perrieri	34.34	6.00e-138	484.00
IUUC-Loc-051821	Lepisosteus oculatus	67.31	0.00e+00	1376.00
IUUC-Lma-053178	Leptosphaeria maculans	35.74	3.00e-105	375.00
IUUC-Laf-053552	Loxodonta africana	96.71	0.00e+00	1872.00
IUUC-Mcc-054667	Macaca mulatta	96.81	0.00e+00	1871.00
IUUC-Meu-056422	Macropus eugenii	93.90	0.00e+00	882.00
IUUC-Mor-056981	Magnaporthe oryzae	33.40	2.00e-126	446.00
IUUC-Mtr-058703	Medicago truncatula	34.11	2.00e-140	493.00
IUUC-Mla-059088	Melampsora laricipopulina	34.82	2.00e-101	362.00
IUUC-Mga-059798	Meleagris gallopavo	73.72	0.00e+00	1508.00
IUUC-Mvi-060404	Microbotryum violaceum	33.70	1.00e-130	461.00
IUUC-Mmr-061630	Microcebus murinus	97.74	0.00e+00	1888.00
IUUC-Mdo-062354	Monodelphis domestica	93.83	0.00e+00	1885.00
IUUC-Mmu-063199	Mus musculus	95.68	0.00e+00	1871.00
IUUC-Mac-065595	Musa acuminata	35.57	2.00e-120	426.00
IUUC-Mpu-066596	Mustela putorius furo	97.23	0.00e+00	1902.00
IUUC-Mlu-067455	Myotis lucifugus	97.23	0.00e+00	1879.00
IUUC-Nfi-068565	Neosartorya fischeri	32.86	3.00e-121	429.00
IUUC-Ncr-068748	Neurospora crassa	33.86	9.00e-132	464.00
IUUC-Nle-068979	Nomascus leucogenys	96.74	0.00e+00	1679.00
IUUC-Opr-070711	Ochotona princeps	95.38	0.00e+00	1859.00
IUUC-Ont-072603	Oreochromis niloticus	65.92	0.00e+00	1365.00
IUUC-Oan-073136	Ornithorhynchus anatinus	84.93	0.00e+00	850.00
IUUC-Ocu-074496	Oryctolagus cuniculus	96.92	0.00e+00	1881.00
IUUC-Oba-075933	Oryza barthii	33.26	2.00e-119	423.00
IUUC-Obr-076290	Oryza brachyantha	33.78	4.00e-140	492.00
IUUC-Ogu-078728	Oryza glumaepatula	33.26	1.00e-119	424.00
IUUC-Oin-079954	Oryza indica	33.26	3.00e-131	462.00
IUUC-Olo-081033	Oryza longistaminata	32.03	2.00e-113	403.00
IUUC-Ome-081797	Oryza meridionalis	32.89	4.00e-126	446.00
IUUC-Oni-082802	Oryza nivara	33.26	1.00e-119	424.00
IUUC-Opu-083595	Oryza punctata	34.81	2.00e-139	489.00
IUUC-Oru-084199	Oryza rufipogon	33.26	1.00e-119	424.00
IUUC-Osa-085349	Oryza sativa	33.78	3.00e-139	489.00
IUUC-Ola-087482	Oryzias latipes	65.92	0.00e+00	1351.00
IUUC-Olu-087797	Ostreococcus lucimarinus	25.52	2.00e-68	254.00
IUUC-Oga-088817	Otolemur garnettii	96.81	0.00e+00	1910.00
IUUC-Oar-090350	Ovis aries	97.64	0.00e+00	1523.00
IUUC-Ptr-090999	Pan troglodytes	96.81	0.00e+00	1873.00
IUUC-Pan-092704	Papio anubis	96.81	0.00e+00	1871.00
IUUC-Psi-093529	Pelodiscus sinensis	73.41	0.00e+00	1481.00
IUUC-Pma-094400	Petromyzon marinus	56.73	0.00e+00	1129.00
IUUC-Pno-094875	Phaeosphaeria nodorum	33.30	1.00e-125	444.00
IUUC-Ppa-095231	Physcomitrella patens	33.88	2.00e-139	490.00
IUUC-Pfo-096967	Poecilia formosa	65.31	0.00e+00	1358.00
IUUC-Pab-098300	Pongo abelii	96.81	0.00e+00	1871.00
IUUC-Pop-098966	Populus trichocarpa	34.38	2.00e-149	523.00
IUUC-Pca-100643	Procavia capensis	95.11	0.00e+00	1779.00
IUUC-Ppe-101589	Prunus persica	33.64	8.00e-144	504.00
IUUC-Pva-102766	Pteropus vampyrus	96.81	0.00e+00	1837.00
IUUC-Pgr-103330	Puccinia graminis	30.79	6.00e-117	416.00
IUUC-Ptt-103809	Puccinia triticina	32.00	5.00e-99	356.00
IUUC-Pte-104319	Pyrenophora teres	32.39	1.00e-124	441.00
IUUC-Pyt-104798	Pyrenophora triticirepentis	30.95	2.00e-112	400.00
IUUC-Rno-105817	Rattus norvegicus	95.27	0.00e+00	1866.00
IUUC-Sce-106255	Saccharomyces cerevisiae	23.59	4.00e-47	183.00
IUUC-Sha-107479	Sarcophilus harrisii	94.20	0.00e+00	1879.00
IUUC-Sja-107976	Schizosaccharomyces japonicus	24.80	1.00e-74	275.00
IUUC-Spo-108146	Schizosaccharomyces pombe	26.46	3.00e-79	290.00
IUUC-Ssl-108663	Sclerotinia sclerotiorum	34.01	9.00e-118	418.00
IUUC-Smo-109585	Selaginella moellendorffii	34.64	2.00e-132	466.00
IUUC-Sit-110275	Setaria italica	34.39	2.00e-138	486.00
IUUC-Sly-111073	Solanum lycopersicum	34.60	3.00e-144	506.00
IUUC-Stu-112392	Solanum tuberosum	29.89	5.00e-16	77.40
IUUC-Sar-113718	Sorex araneus	93.33	0.00e+00	1800.00
IUUC-Sbi-114080	Sorghum bicolor	34.56	6.00e-143	501.00
IUUC-Sre-115160	Sporisorium reilianum	32.36	3.00e-129	456.00
IUUC-Ssc-115997	Sus scrofa	97.94	0.00e+00	1902.00
IUUC-Tgu-116904	Taeniopygia guttata	73.33	0.00e+00	1345.00
IUUC-Tru-117946	Takifugu rubripes	64.80	0.00e+00	1352.00
IUUC-Tni-119692	Tetraodon nigroviridis	65.11	0.00e+00	1348.00
IUUC-Tca-121455	Theobroma cacao	33.44	3.00e-145	509.00
IUUC-Tre-122128	Trichoderma reesei	32.69	2.00e-128	453.00
IUUC-Tvi-122657	Trichoderma virens	33.03	6.00e-131	461.00
IUUC-Tae-125953	Triticum aestivum	33.81	3.00e-135	476.00
IUUC-Tur-126110	Triticum urartu	31.04	9.00e-104	371.00
IUUC-Tme-127173	Tuber melanosporum	30.76	5.00e-109	389.00
IUUC-Ttr-128420	Tursiops truncatus	98.36	0.00e+00	1934.00
IUUC-Uma-129580	Ustilago maydis	32.03	2.00e-128	453.00
IUUC-Vda-129790	Verticillium dahliae	32.19	5.00e-117	415.00
IUUC-Vvi-131095	Vitis vinifera	33.13	7.00e-140	491.00
IUUC-Xtr-131906	Xenopus tropicalis	68.86	0.00e+00	1379.00
IUUC-Xma-134197	Xiphophorus maculatus	65.92	0.00e+00	1361.00
IUUC-Yli-134617	Yarrowia lipolytica	28.30	3.00e-105	376.00
IUUC-Zma-134979	Zea mays	32.09	6.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence