iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049830

Ensembl Protein ID

ENSLACP00000001033.2

UniProt Accession

H2ZUG2; H2ZUG2_LATCH

Genbank Protein ID

ENSLACP00000001033

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01242559

Gene Name

PLRG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000000924.2	ENSLACT00000001043.2	ENSLACP00000001033.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-43	143.2	202	238
UBD/Beta-Prp	1.80e-65	221.3	203	444

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++++c+a  ++   +v+Gs D tik+WDl +g+l
   Q: 202  GHLGWIRCIAVePGnQWFVTGSADRTIKIWDLASGKL 238
           8***********77799***************99987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h + i+c+++ p++++++tgs+d+tik+wd+ +gkl  sl gh ++v+ v+ s ++++l +++eD+ +k wdl+ +k +++++gh + v
   Q: 203  HLGWIRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVTVSARSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAV 291
           556799*********************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
           ++l+++p+ d+lv+ s+d+t+rvwd++t+  ++ tl+gh+ +v +v+ +  +  +++Gs D+t+rlWdl  gk   tlt  h++sv+ l
   Q: 292  YDLDLHPTIDVLVTCSRDSTARVWDIRTKASVH-TLTGHTNAVATVKCQAAEPQVITGSHDTTIRLWDLVAGKTRVTLTN-HKKSVRAL 378
           *********************************.********************************************97.******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
            +++ +  ++sgs d+ +k w +  g+ ++ l gh++ ++ +++   d  lvsg++ g+  +Wd r+g
   Q: 379  VLHPRQYTFASGSPDN-IKQWKFPDGSFIQNLSGHSAIINTLAVN-SDGVLVSGADNGTMHLWDWRTG 444
           **************96.***************************9.999****************998 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MVEEVQKHSV HTLVFRSLKR THDMFVADHA KSISADETSY KLKMAVKLKT EYSRVLHMPV 60
LKEVREKGSH NAVDHYGHEQ YSMAHGQESD YMITGTHPYP SGPGVALTAD TQLQKLPSEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTCCTCCT GGCGGAGAGG GGAGCGCTGT GGGCTTCTAA TCAACCAGCT CTTATTTCCG 60
GTGCTTCCAT CTACACCCCC CCCCCCGATA AAACTCCAGA CTGCTTGGTG CCTGGAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0043066--P:negative regulation of apoptotic process
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator

KEGG

lcm:102363822

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	53.85	3.00e-130	458.00
IUUC-Aml-001605	Ailuropoda melanoleuca	83.85	0.00e+00	902.00
IUUC-Atr-002757	Amborella trichopoda	46.64	2.00e-127	449.00
IUUC-Apl-003198	Anas platyrhynchos	86.43	0.00e+00	935.00
IUUC-Aca-004683	Anolis carolinensis	86.63	0.00e+00	945.00
IUUC-Aly-005775	Arabidopsis lyrata	54.57	3.00e-126	445.00
IUUC-Ath-007460	Arabidopsis thaliana	57.06	1.00e-124	439.00
IUUC-Ago-007884	Ashbya gossypii	51.36	2.00e-107	382.00
IUUC-Acl-008153	Aspergillus clavatus	64.33	7.00e-130	456.00
IUUC-Afl-008384	Aspergillus flavus	58.04	2.00e-132	465.00
IUUC-Afu-009045	Aspergillus fumigatus	64.94	1.00e-130	459.00
IUUC-Ani-009229	Aspergillus nidulans	65.14	4.00e-130	457.00
IUUC-Ang-009812	Aspergillus niger	65.62	9.00e-125	439.00
IUUC-Aor-010059	Aspergillus oryzae	58.04	2.00e-132	465.00
IUUC-Ate-010351	Aspergillus terreus	64.94	8.00e-136	476.00
IUUC-Ame-011613	Astyanax mexicanus	62.55	3.00e-166	577.00
IUUC-Bgr-012042	Blumeria graminis	55.33	6.00e-136	477.00
IUUC-Bta-012406	Bos taurus	83.53	0.00e+00	897.00
IUUC-Bci-013760	Botrytis cinerea	61.86	3.00e-134	471.00
IUUC-Bdi-014776	Brachypodium distachyon	57.32	7.00e-134	470.00
IUUC-Bol-016189	Brassica oleracea	54.50	1.00e-126	446.00
IUUC-Bra-018044	Brassica rapa	48.16	1.00e-126	446.00
IUUC-Cel-018651	Caenorhabditis elegans	53.23	6.00e-155	540.00
IUUC-Cja-019974	Callithrix jacchus	83.91	0.00e+00	902.00
IUUC-Cfa-021085	Canis familiaris	83.91	0.00e+00	905.00
IUUC-Cpo-021458	Cavia porcellus	83.72	0.00e+00	905.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	61.68	7.00e-125	439.00
IUUC-Csa-023883	Chlorocebus sabaeus	83.53	0.00e+00	897.00
IUUC-Cho-024623	Choloepus hoffmanni	82.75	0.00e+00	881.00
IUUC-Cin-025190	Ciona intestinalis	61.43	0.00e+00	644.00
IUUC-Csv-026367	Ciona savignyi	59.73	0.00e+00	641.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	66.26	2.00e-140	492.00
IUUC-Cne-027069	Cryptococcus neoformans	51.43	1.00e-128	452.00
IUUC-Cme-027233	Cyanidioschyzon merolae	29.83	3.00e-35	142.00
IUUC-Dre-028260	Danio rerio	84.05	0.00e+00	914.00
IUUC-Dno-029112	Dasypus novemcinctus	84.11	0.00e+00	903.00
IUUC-Dor-031118	Dipodomys ordii	87.59	0.00e+00	749.00
IUUC-Dse-031493	Dothistroma septosporum	55.12	6.00e-126	444.00
IUUC-Dme-032138	Drosophila melanogaster	76.00	2.00e-160	558.00
IUUC-Ete-032411	Echinops telfairi	73.78	0.00e+00	724.00
IUUC-Eca-033521	Equus caballus	84.50	0.00e+00	914.00
IUUC-Eeu-035249	Erinaceus europaeus	76.40	0.00e+00	627.00
IUUC-Fca-036358	Felis catus	83.33	0.00e+00	899.00
IUUC-Fal-036933	Ficedula albicollis	86.82	0.00e+00	933.00
IUUC-Fox-037713	Fusarium oxysporum	65.34	5.00e-139	487.00
IUUC-Fso-038380	Fusarium solani	65.75	3.00e-139	488.00
IUUC-Gmo-039133	Gadus morhua	81.02	0.00e+00	875.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.97	4.00e-133	468.00
IUUC-Gga-041176	Gallus gallus	85.27	0.00e+00	926.00
IUUC-Gac-042344	Gasterosteus aculeatus	82.30	0.00e+00	900.00
IUUC-Gma-043328	Glycine max	50.20	4.00e-131	461.00
IUUC-Ggo-044478	Gorilla gorilla	83.33	0.00e+00	894.00
IUUC-Hsa-046037	Homo sapiens	83.53	0.00e+00	896.00
IUUC-Hvu-047349	Hordeum vulgare	58.54	2.00e-134	472.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	84.11	0.00e+00	907.00
IUUC-Kpa-049343	Komagataella pastoris	59.08	2.00e-119	422.00
IUUC-Lpe-051442	Leersia perrieri	49.09	7.00e-132	464.00
IUUC-Loc-051794	Lepisosteus oculatus	86.49	0.00e+00	902.00
IUUC-Lma-053137	Leptosphaeria maculans	44.83	4.00e-127	448.00
IUUC-Laf-053471	Loxodonta africana	83.66	0.00e+00	902.00
IUUC-Mcc-055627	Macaca mulatta	83.72	0.00e+00	899.00
IUUC-Meu-056148	Macropus eugenii	76.61	0.00e+00	815.00
IUUC-Mor-056960	Magnaporthe oryzae	66.56	4.00e-138	484.00
IUUC-Mtr-057816	Medicago truncatula	60.18	5.00e-127	447.00
IUUC-Mla-059031	Melampsora laricipopulina	62.22	3.00e-130	457.00
IUUC-Mga-059337	Meleagris gallopavo	85.60	0.00e+00	927.00
IUUC-Mvi-060217	Microbotryum violaceum	66.25	5.00e-131	461.00
IUUC-Mmr-061018	Microcebus murinus	84.50	0.00e+00	911.00
IUUC-Mdo-062863	Monodelphis domestica	85.85	0.00e+00	922.00
IUUC-Mmu-063988	Mus musculus	83.14	0.00e+00	894.00
IUUC-Mac-064459	Musa acuminata	48.58	6.00e-124	437.00
IUUC-Mpu-066559	Mustela putorius furo	84.11	0.00e+00	908.00
IUUC-Mlu-067361	Myotis lucifugus	84.60	0.00e+00	888.00
IUUC-Nfi-068492	Neosartorya fischeri	65.24	9.00e-131	459.00
IUUC-Ncr-068808	Neurospora crassa	65.44	8.00e-138	483.00
IUUC-Nle-069875	Nomascus leucogenys	83.72	0.00e+00	899.00
IUUC-Opr-070462	Ochotona princeps	93.98	6.00e-153	533.00
IUUC-Ont-071365	Oreochromis niloticus	82.10	0.00e+00	909.00
IUUC-Oan-072708	Ornithorhynchus anatinus	87.55	0.00e+00	947.00
IUUC-Ocu-074594	Oryctolagus cuniculus	83.95	0.00e+00	899.00
IUUC-Oba-075570	Oryza barthii	61.02	9.00e-129	453.00
IUUC-Obr-076366	Oryza brachyantha	63.27	8.00e-93	332.00
IUUC-Ogl-077153	Oryza glaberrima	60.73	9.00e-128	449.00
IUUC-Ogu-078540	Oryza glumaepatula	60.73	2.00e-128	452.00
IUUC-Oin-079612	Oryza indica	59.89	1.00e-126	446.00
IUUC-Olo-081077	Oryza longistaminata	59.89	1.00e-126	446.00
IUUC-Ome-081236	Oryza meridionalis	61.83	8.00e-126	443.00
IUUC-Oni-082499	Oryza nivara	60.73	2.00e-128	452.00
IUUC-Opu-083499	Oryza punctata	59.89	2.00e-126	445.00
IUUC-Oru-084276	Oryza rufipogon	60.73	2.00e-128	452.00
IUUC-Osa-085849	Oryza sativa	60.73	2.00e-128	452.00
IUUC-Ola-086655	Oryzias latipes	79.61	0.00e+00	871.00
IUUC-Olu-087637	Ostreococcus lucimarinus	58.61	2.00e-119	422.00
IUUC-Oga-087934	Otolemur garnettii	84.53	0.00e+00	909.00
IUUC-Oar-090185	Ovis aries	82.79	0.00e+00	889.00
IUUC-Ptr-091198	Pan troglodytes	83.72	0.00e+00	899.00
IUUC-Pan-092622	Papio anubis	83.53	0.00e+00	897.00
IUUC-Psi-093320	Pelodiscus sinensis	85.30	0.00e+00	928.00
IUUC-Pma-094638	Petromyzon marinus	79.18	0.00e+00	867.00
IUUC-Pno-094826	Phaeosphaeria nodorum	46.53	1.00e-104	373.00
IUUC-Ppa-095576	Physcomitrella patens	64.63	2.00e-125	442.00
IUUC-Pfo-096894	Poecilia formosa	81.98	0.00e+00	895.00
IUUC-Pab-098020	Pongo abelii	83.72	0.00e+00	898.00
IUUC-Pop-099180	Populus trichocarpa	47.17	9.00e-127	446.00
IUUC-Pca-100909	Procavia capensis	77.20	0.00e+00	696.00
IUUC-Ppe-101346	Prunus persica	46.84	5.00e-126	444.00
IUUC-Pva-102167	Pteropus vampyrus	69.96	0.00e+00	706.00
IUUC-Pgr-103516	Puccinia graminis	51.04	2.00e-131	462.00
IUUC-Ptt-103738	Puccinia triticina	51.05	3.00e-132	465.00
IUUC-Pte-104352	Pyrenophora teres	56.79	6.00e-132	464.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	57.34	5.00e-133	467.00
IUUC-Rno-105291	Rattus norvegicus	82.95	0.00e+00	891.00
IUUC-Sce-106204	Saccharomyces cerevisiae	50.45	4.00e-105	374.00
IUUC-Sha-106943	Sarcophilus harrisii	85.49	0.00e+00	914.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	65.71	2.00e-130	459.00
IUUC-Spo-108049	Schizosaccharomyces pombe	64.24	4.00e-136	477.00
IUUC-Smo-109043	Selaginella moellendorffii	61.63	1.00e-126	445.00
IUUC-Sit-110431	Setaria italica	57.56	4.00e-134	471.00
IUUC-Sly-111391	Solanum lycopersicum	62.94	1.00e-120	426.00
IUUC-Stu-112364	Solanum tuberosum	56.25	1.00e-97	348.00
IUUC-Sar-113450	Sorex araneus	93.98	0.00e+00	696.00
IUUC-Sbi-113829	Sorghum bicolor	50.51	5.00e-133	467.00
IUUC-Sre-115153	Sporisorium reilianum	61.19	2.00e-124	439.00
IUUC-Ssc-115798	Sus scrofa	83.75	0.00e+00	905.00
IUUC-Tgu-117417	Taeniopygia guttata	86.94	0.00e+00	936.00
IUUC-Tru-117615	Takifugu rubripes	78.75	0.00e+00	832.00
IUUC-Tsy-119480	Tarsius syrichta	84.21	0.00e+00	897.00
IUUC-Tni-119847	Tetraodon nigroviridis	79.77	0.00e+00	870.00
IUUC-Tca-121287	Theobroma cacao	47.55	7.00e-130	457.00
IUUC-Tre-122010	Trichoderma reesei	66.08	7.00e-144	503.00
IUUC-Tvi-122475	Trichoderma virens	65.19	5.00e-143	500.00
IUUC-Tae-124397	Triticum aestivum	50.61	3.00e-134	471.00
IUUC-Tur-126116	Triticum urartu	50.24	1.00e-102	366.00
IUUC-Tme-126992	Tuber melanosporum	65.85	7.00e-138	483.00
IUUC-Tbe-127803	Tupaia belangeri	74.59	0.00e+00	648.00
IUUC-Ttr-128933	Tursiops truncatus	84.11	0.00e+00	905.00
IUUC-Uma-129447	Ustilago maydis	61.24	8.00e-119	420.00
IUUC-Vda-129780	Verticillium dahliae	65.64	3.00e-138	484.00
IUUC-Vpa-130557	Vicugna pacos	68.40	9.00e-88	317.00
IUUC-Vvi-130918	Vitis vinifera	46.17	9.00e-122	430.00
IUUC-Xtr-132409	Xenopus tropicalis	86.05	0.00e+00	898.00
IUUC-Xma-133420	Xiphophorus maculatus	81.52	0.00e+00	892.00
IUUC-Yli-134362	Yarrowia lipolytica	52.36	5.00e-123	434.00
IUUC-Zma-135804	Zea mays	60.17	1.00e-126	446.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence