iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003918

Ensembl Protein ID

ENSAPLP00000002414.1

UniProt Accession

U3I593; U3I593_ANAPL

Genbank Protein ID

ENSAPLP00000002414

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01064216

Gene Name

RACK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000002910.1	ENSAPLT00000003003.1	ENSAPLP00000002414.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-37	124.0	67	97
UBD/Beta-Prp	8.30e-50	169.3	1	235

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt +v ++af sd + +vsGs+D+tik+W+
   Q: 67   GHTKDVLSVAFsSDnRQIVSGSRDKTIKLWN 97
           8***********88899*************9 PP

UBD/Beta-Prp

   S: 31   dgtikvwdvttgkl.....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGsh 114
           d+ti+ w++t+  +      r l gh+ +v++v +s+dg++ ++gs D+t+++wdl tg++++ + gh+++vls++fs ++  +vsGs+
   Q: 1    DKTIIMWKLTRDETnygipQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSR 89
           89*********999*************************************************************************** PP
   S: 115  drtirvwdletgqclee.tlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsl 200
           d+ti++w++  g c ++  ++ h+++v+cv+++p++   ++vs++ D+ v++W+l++ kl +   g ht++ + ++++++g  ++sg++
   Q: 90   DKTIKLWNTL-GVCKYTvQDESHSEWVSCVRFSPNSsnPIIVSCGWDKLVKVWNLANCKLKTNHIG-HTGYLNTVTVSPDGSLCASGGK 176
           *******765.45555447899************998569***************77777766676.********************** PP
   S: 201  dgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
           dg+  lwdl +g+ ++tl g  d ++ + fs  + + ++++  +si+iWdl+ + ++  l+
   Q: 177  DGQAMLWDLNEGKHLYTLDGG-DIINALCFS-PNRYWLCAATGPSIKIWDLEGKIIVDELK 235
           ******************996.577878888.7888899999********99776666555 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

DKTIIMWKLT RDETNYGIPQ RALRGHSHFV SDVVISSDGQ FALSGSWDGT LRLWDLTTGT 60
TTRRFVGHTK DVLSVAFSSD NRQIVSGSRD KTIKLWNTLG VCKYTVQDES HSEWVSCVRF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACAAAACCA TCATCATGTG GAAGCTGACC CGCGATGAGA CCAACTACGG GATCCCGCAG 60
CGAGCCCTGC GCGGCCACTC GCACTTTGTC AGCGACGTGG TCATCTCCTC CGACGGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0070062--C:extracellular exosome
GO:1990630--C:IRE1-RACK1-PP2A complex
GO:0030496--C:midbody
GO:0005739--C:mitochondrion
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0001891--C:phagocytic cup
GO:0008656--F:cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0008200--F:ion channel inhibitor activity
GO:0030292--F:protein tyrosine kinase inhibitor activity
GO:0003723--F:RNA binding
GO:0035591--F:signaling adaptor activity
GO:0071333--P:cellular response to glucose stimulus
GO:0071363--P:cellular response to growth factor stimulus
GO:0030308--P:negative regulation of cell growth
GO:0010629--P:negative regulation of gene expression
GO:1903208--P:negative regulation of hydrogen peroxide-induced neuron death
GO:0033137--P:negative regulation of peptidyl-serine phosphorylation
GO:0050765--P:negative regulation of phagocytosis
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0043473--P:pigmentation
GO:0030822--P:positive regulation of cAMP catabolic process
GO:0030335--P:positive regulation of cell migration
GO:0051343--P:positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0042998--P:positive regulation of Golgi to plasma membrane protein transport
GO:0043547--P:positive regulation of GTPase activity
GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway
GO:0051901--P:positive regulation of mitochondrial depolarization
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032464--P:positive regulation of protein homooligomerization
GO:0001934--P:positive regulation of protein phosphorylation
GO:0051726--P:regulation of cell cycle
GO:0006412--P:translation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000096	Aegilops tauschii	67.76	3.00e-93	335.00
IUUC-Aml-001935	Ailuropoda melanoleuca	100.00	2.00e-166	577.00
IUUC-Atr-002694	Amborella trichopoda	69.68	2.00e-114	404.00
IUUC-Aca-004869	Anolis carolinensis	100.00	2.00e-166	577.00
IUUC-Aly-005671	Arabidopsis lyrata	68.06	3.00e-115	407.00
IUUC-Ath-007105	Arabidopsis thaliana	69.34	2.00e-116	411.00
IUUC-Ago-007720	Ashbya gossypii	55.56	2.00e-88	318.00
IUUC-Acl-008156	Aspergillus clavatus	73.19	7.00e-123	432.00
IUUC-Afl-008684	Aspergillus flavus	72.46	1.00e-121	428.00
IUUC-Afu-008867	Aspergillus fumigatus	74.28	5.00e-124	436.00
IUUC-Ani-009221	Aspergillus nidulans	73.55	5.00e-123	433.00
IUUC-Ang-009843	Aspergillus niger	72.46	2.00e-121	428.00
IUUC-Aor-010193	Aspergillus oryzae	72.46	1.00e-121	428.00
IUUC-Ate-010420	Aspergillus terreus	72.46	3.00e-121	427.00
IUUC-Ame-010884	Astyanax mexicanus	96.44	8.00e-164	568.00
IUUC-Bgr-012064	Blumeria graminis	70.65	3.00e-119	421.00
IUUC-Bta-013357	Bos taurus	100.00	2.00e-166	577.00
IUUC-Bci-013862	Botrytis cinerea	72.83	4.00e-123	433.00
IUUC-Bdi-014690	Brachypodium distachyon	64.51	7.00e-106	376.00
IUUC-Bol-016231	Brassica oleracea	69.69	2.00e-117	414.00
IUUC-Bra-016879	Brassica rapa	69.23	6.00e-116	409.00
IUUC-Cel-018335	Caenorhabditis elegans	70.32	4.00e-112	397.00
IUUC-Cja-019914	Callithrix jacchus	100.00	2.00e-166	577.00
IUUC-Cfa-020755	Canis familiaris	100.00	2.00e-166	577.00
IUUC-Cpo-022377	Cavia porcellus	100.00	6.00e-167	579.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	76.53	7.00e-126	442.00
IUUC-Csa-023025	Chlorocebus sabaeus	100.00	2.00e-166	578.00
IUUC-Cin-025647	Ciona intestinalis	75.99	9.00e-128	449.00
IUUC-Csv-026027	Ciona savignyi	76.34	3.00e-128	450.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	74.64	3.00e-125	440.00
IUUC-Cne-026930	Cryptococcus neoformans	72.46	4.00e-122	430.00
IUUC-Cme-027251	Cyanidioschyzon merolae	65.22	8.00e-111	392.00
IUUC-Dre-028669	Danio rerio	95.73	6.00e-163	566.00
IUUC-Dno-029470	Dasypus novemcinctus	97.83	1.00e-132	466.00
IUUC-Dor-031098	Dipodomys ordii	91.18	1.00e-129	455.00
IUUC-Dse-031255	Dothistroma septosporum	72.46	4.00e-122	430.00
IUUC-Dme-032118	Drosophila melanogaster	77.78	3.00e-131	460.00
IUUC-Ete-033182	Echinops telfairi	83.41	2.00e-105	374.00
IUUC-Eca-033296	Equus caballus	100.00	6.00e-87	311.00
IUUC-Eeu-034771	Erinaceus europaeus	93.95	2.00e-154	537.00
IUUC-Fca-036315	Felis catus	100.00	2.00e-166	577.00
IUUC-Fal-036990	Ficedula albicollis	97.22	5.00e-103	367.00
IUUC-Fox-037702	Fusarium oxysporum	73.55	6.00e-124	436.00
IUUC-Fso-038384	Fusarium solani	74.64	7.00e-125	439.00
IUUC-Gmo-039630	Gadus morhua	94.12	5.00e-155	539.00
IUUC-Ggr-039985	Gaeumannomyces graminis	74.28	1.00e-124	438.00
IUUC-Gga-040540	Gallus gallus	100.00	2.00e-166	577.00
IUUC-Gac-041316	Gasterosteus aculeatus	91.27	5.00e-153	533.00
IUUC-Gma-042872	Glycine max	68.53	3.00e-115	407.00
IUUC-Ggo-045253	Gorilla gorilla	100.00	2.00e-166	577.00
IUUC-Hsa-046809	Homo sapiens	100.00	2.00e-166	577.00
IUUC-Hvu-047683	Hordeum vulgare	65.19	1.00e-106	379.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	100.00	2.00e-166	577.00
IUUC-Kpa-049214	Komagataella pastoris	57.61	4.00e-86	310.00
IUUC-Lch-049634	Latimeria chalumnae	93.59	2.00e-159	554.00
IUUC-Lpe-050762	Leersia perrieri	65.07	1.00e-106	379.00
IUUC-Loc-052163	Lepisosteus oculatus	97.15	2.00e-164	570.00
IUUC-Lma-053113	Leptosphaeria maculans	74.28	2.00e-124	437.00
IUUC-Laf-054422	Loxodonta africana	100.00	2.00e-166	577.00
IUUC-Mcc-055348	Macaca mulatta	100.00	2.00e-166	577.00
IUUC-Meu-056543	Macropus eugenii	100.00	8.00e-167	578.00
IUUC-Mor-057107	Magnaporthe oryzae	74.28	4.00e-125	440.00
IUUC-Mpo-057487	Magnaporthe poae	74.64	4.00e-125	440.00
IUUC-Mtr-058808	Medicago truncatula	68.88	8.00e-116	409.00
IUUC-Mla-058909	Melampsora laricipopulina	75.09	8.00e-125	439.00
IUUC-Mga-059387	Meleagris gallopavo	100.00	2.00e-166	577.00
IUUC-Mvi-060392	Microbotryum violaceum	71.38	6.00e-122	429.00
IUUC-Mmr-061141	Microcebus murinus	89.32	4.00e-135	473.00
IUUC-Mdo-062932	Monodelphis domestica	100.00	2.00e-166	577.00
IUUC-Mmu-064132	Mus musculus	100.00	2.00e-166	577.00
IUUC-Mac-064447	Musa acuminata	62.85	6.00e-99	353.00
IUUC-Mpu-066721	Mustela putorius furo	98.93	4.00e-163	566.00
IUUC-Mlu-068221	Myotis lucifugus	99.29	2.00e-154	537.00
IUUC-Nfi-068344	Neosartorya fischeri	74.28	5.00e-124	436.00
IUUC-Ncr-068722	Neurospora crassa	72.83	1.00e-122	431.00
IUUC-Nle-069865	Nomascus leucogenys	100.00	1.00e-166	578.00
IUUC-Opr-071100	Ochotona princeps	84.73	4.00e-130	457.00
IUUC-Ont-072287	Oreochromis niloticus	94.66	2.00e-161	561.00
IUUC-Oan-072788	Ornithorhynchus anatinus	100.00	2.00e-166	577.00
IUUC-Ocu-073844	Oryctolagus cuniculus	97.15	8.00e-160	555.00
IUUC-Oba-075652	Oryza barthii	63.19	6.00e-101	360.00
IUUC-Obr-076099	Oryza brachyantha	63.48	2.00e-105	375.00
IUUC-Ogl-077804	Oryza glaberrima	64.51	5.00e-107	380.00
IUUC-Ogu-078035	Oryza glumaepatula	65.64	4.00e-107	380.00
IUUC-Oin-079327	Oryza indica	65.64	4.00e-107	380.00
IUUC-Olo-081084	Oryza longistaminata	65.64	4.00e-107	380.00
IUUC-Ome-081366	Oryza meridionalis	64.85	2.00e-107	381.00
IUUC-Oni-082682	Oryza nivara	64.85	2.00e-107	381.00
IUUC-Opu-084010	Oryza punctata	64.85	1.00e-107	382.00
IUUC-Oru-084358	Oryza rufipogon	64.85	2.00e-107	381.00
IUUC-Osa-085296	Oryza sativa	64.85	2.00e-107	381.00
IUUC-Ola-086400	Oryzias latipes	94.31	4.00e-161	560.00
IUUC-Olu-087817	Ostreococcus lucimarinus	78.01	5.00e-130	456.00
IUUC-Oga-088811	Otolemur garnettii	100.00	2.00e-166	577.00
IUUC-Oar-089962	Ovis aries	100.00	2.00e-166	577.00
IUUC-Ptr-091340	Pan troglodytes	100.00	2.00e-166	577.00
IUUC-Pan-091946	Papio anubis	100.00	2.00e-166	577.00
IUUC-Pma-094535	Petromyzon marinus	93.24	7.00e-159	552.00
IUUC-Pno-095100	Phaeosphaeria nodorum	77.84	3.00e-82	297.00
IUUC-Ppa-095588	Physcomitrella patens	76.90	3.00e-126	444.00
IUUC-Pfo-097311	Poecilia formosa	94.31	4.00e-161	560.00
IUUC-Pab-097863	Pongo abelii	100.00	1.00e-166	578.00
IUUC-Pop-099345	Populus trichocarpa	69.44	3.00e-118	417.00
IUUC-Pca-100594	Procavia capensis	98.93	1.00e-164	572.00
IUUC-Ppe-101743	Prunus persica	67.71	5.00e-114	403.00
IUUC-Pva-102746	Pteropus vampyrus	81.85	5.00e-128	449.00
IUUC-Pgr-103375	Puccinia graminis	57.40	4.00e-83	300.00
IUUC-Ptt-103839	Puccinia triticina	74.73	3.00e-123	434.00
IUUC-Pte-104026	Pyrenophora teres	74.28	2.00e-124	437.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	74.28	2.00e-124	437.00
IUUC-Rno-104964	Rattus norvegicus	100.00	2.00e-166	577.00
IUUC-Sce-106224	Saccharomyces cerevisiae	52.86	1.00e-83	302.00
IUUC-Sha-107409	Sarcophilus harrisii	100.00	2.00e-166	577.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	66.79	2.00e-111	395.00
IUUC-Spo-108297	Schizosaccharomyces pombe	64.98	3.00e-108	384.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	72.83	4.00e-123	433.00
IUUC-Smo-109017	Selaginella moellendorffii	72.14	6.00e-118	416.00
IUUC-Sit-110060	Setaria italica	65.98	9.00e-109	385.00
IUUC-Sly-111496	Solanum lycopersicum	70.28	1.00e-115	409.00
IUUC-Stu-112757	Solanum tuberosum	68.53	1.00e-111	395.00
IUUC-Sar-113173	Sorex araneus	100.00	2.00e-166	577.00
IUUC-Sbi-114681	Sorghum bicolor	64.60	4.00e-106	377.00
IUUC-Sre-115107	Sporisorium reilianum	74.28	4.00e-126	443.00
IUUC-Ssc-116218	Sus scrofa	99.64	6.00e-166	575.00
IUUC-Tru-118202	Takifugu rubripes	92.53	3.00e-158	550.00
IUUC-Tni-120260	Tetraodon nigroviridis	92.17	1.00e-157	548.00
IUUC-Tca-120951	Theobroma cacao	68.88	4.00e-117	413.00
IUUC-Tre-121961	Trichoderma reesei	75.00	9.00e-126	442.00
IUUC-Tvi-122447	Trichoderma virens	74.64	1.00e-124	439.00
IUUC-Tae-123560	Triticum aestivum	64.85	3.00e-106	377.00
IUUC-Tur-126335	Triticum urartu	67.78	3.00e-104	370.00
IUUC-Tme-127105	Tuber melanosporum	68.59	6.00e-113	399.00
IUUC-Tbe-128021	Tupaia belangeri	79.70	3.00e-86	310.00
IUUC-Ttr-128637	Tursiops truncatus	86.83	9.00e-140	489.00
IUUC-Uma-129634	Ustilago maydis	74.64	3.00e-126	443.00
IUUC-Vda-129923	Verticillium dahliae	73.91	4.00e-124	437.00
IUUC-Vpa-130410	Vicugna pacos	100.00	1.00e-96	345.00
IUUC-Vvi-131115	Vitis vinifera	69.10	6.00e-117	413.00
IUUC-Xtr-132105	Xenopus tropicalis	96.09	1.00e-163	568.00
IUUC-Xma-133875	Xiphophorus maculatus	94.66	3.00e-161	560.00
IUUC-Yli-134624	Yarrowia lipolytica	60.56	8.00e-106	376.00
IUUC-Zma-134711	Zea mays	64.60	1.00e-105	375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence